The DOI matches its Crossref record; 93 of the 96 references it cites were found in a registry or an index.
Potential pharmacological applications of polyphenolic derivatives from marine brown algae
Abstract
Recently, the isolation and characterization of the biologically active components from seaweeds have gained much attention from various research groups across the world. The marine algae have been studied for biologically active components and phlorotannins are one among them. Among marine algae, brown algal species such as Ecklonia cava, Eisenia arborea, Ecklonia stolinifera and Eisenia bicyclis have been studied for their potential biological activities. Majority of the investigations on phlorotannins derived from brown algae have exhibited their potentiality as antioxidant, anti-inflammatory, antidiabetic, antitumor, antihypertensive, anti-allergic, hyaluronidase enzyme inhibition and in matrix metalloproteinases (MMPs) inhibition activity. In this review, we have made an attempt to discuss the potential biological activities of phlorotannins from marine brown algae and their possible candidature in the pharmaceutical applications.
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“Phenolic compounds are commonly classified into 5 large groups: Flavonoids (the largest subgroup and associated with different bioactivities, among which, as previously described, the antioxidant, and radical scavenging activity) [158,159], lignans, tannins, tocopherols, and phenolic acids [160].”
From The Potential of Seaweeds as a Source of Functional Ingredients of Prebiotic and Antioxidant Value (2019) · cites this paper as [160]
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Seaweed Phenolics: From Extraction to Applications
Cotas, J., Leandro, A., Monteiro, P., Pacheco, D., Figueirinha, A., Gonçalves, A. M. M., Silva, G., & Pereira, L. (2020) · Marine Drugs · doi:10.3390/md18080384 · Cited by 558
Phenolic content and antioxidant capacity in algal food products
Machu, L., Misurcova, L., Vavra Ambrozova, J., Orsavova, J., Mlcek, J., Sochor, J., & Jurikova, T. (2015) · Molecules · doi:10.3390/molecules20011118 · Cited by 437
In vitro antioxidant properties of crude extracts and compounds from brown algae
Balboa, E. M., Conde, E., Moure, A., Falqué, E., & Domínguez, H. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2012.11.026 · Cited by 436
Singh, R., Parihar, P., Singh, M., Bajguz, A., Kumar, J., Singh, S., Singh, V. P., & Prasad, S. M. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00515 · Cited by 399
Beneficial Effects of Marine Algal Compounds in Cosmeceuticals
Thomas, N. V., & Kim, S. (2013) · Marine Drugs · doi:10.3390/md11010146 · Cited by 305
Metadata
- Authors
- Thomas, N. V., & Kim, S.-K.
- Affiliations
- Pukyong National University (KR)
- Corresponding author
- Kim, Se-Kwon
- Venue
- Environmental Toxicology and Pharmacology
- Publisher
- Elsevier BV
- Published
- 2011-11
- Volume
- 32
- Issue
- 3
- Pages
- 325-335
- ISSN
- 1382-6689 (ISSN-L)
- OpenAlex
- W1997545426
- Cited by
- 269
- References
- 96
- Citations by year
- 2026: 5 · 2025: 9 · 2024: 20 · 2023: 26 · 2022: 24 · 2021: 36 · 2020: 21 · 2019: 25 · 2018: 18 · 2017: 16 · 2016: 9 · 2015: 22 · 2014: 10 · 2013: 19 · 2012: 9
- FWCI
- 1.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Environmental Toxicology and Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Keywords
- phlorotannins, marine brown algae, polyphenols, Ecklonia cava, Eisenia arborea, Eisenia bicyclis, antioxidant activity, anti-inflammatory activity, antidiabetic activity, anticancer activity, antihypertensive effect, anti-allergic activity, hyaluronidase inhibition, matrix metalloproteinase inhibition, pharmaceutical applications
- MeSH terms
- Phaeophyceae, Animals, Anti-Inflammatory Agents, Antihypertensive Agents, Antineoplastic Agents, Antioxidants, Enzyme Inhibitors, Humans, Hyaluronoglucosaminidase, Hypoglycemic Agents, Seaweed, Tannins, Anti-Allergic Agents, Anti-HIV Agents, Polyphenols, Matrix Metalloproteinase Inhibitors
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