Cited by 269Seaweed-derived Bioactive CompoundsMarine and coastal plant biologyPhytochemistry and Biological Activities

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Potential pharmacological applications of polyphenolic derivatives from marine brown algae

Thomas, Noel Vinay, Kim, Se-Kwon·2011·Environmental Toxicology and Pharmacology

DOI 10.1016/j.etap.2011.09.004

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Abstract

Recently, the isolation and characterization of the biologically active components from seaweeds have gained much attention from various research groups across the world. The marine algae have been studied for biologically active components and phlorotannins are one among them. Among marine algae, brown algal species such as Ecklonia cava, Eisenia arborea, Ecklonia stolinifera and Eisenia bicyclis have been studied for their potential biological activities. Majority of the investigations on phlorotannins derived from brown algae have exhibited their potentiality as antioxidant, anti-inflammatory, antidiabetic, antitumor, antihypertensive, anti-allergic, hyaluronidase enzyme inhibition and in matrix metalloproteinases (MMPs) inhibition activity. In this review, we have made an attempt to discuss the potential biological activities of phlorotannins from marine brown algae and their possible candidature in the pharmaceutical applications.

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Seaweed Phenolics: From Extraction to Applications
Cotas, J., Leandro, A., Monteiro, P., Pacheco, D., Figueirinha, A., Gonçalves, A. M. M., Silva, G., & Pereira, L. (2020) · Marine Drugs · doi:10.3390/md18080384 · Cited by 558
Phenolic content and antioxidant capacity in algal food products
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In vitro antioxidant properties of crude extracts and compounds from brown algae
Balboa, E. M., Conde, E., Moure, A., Falqué, E., & Domínguez, H. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2012.11.026 · Cited by 436
Uncovering Potential Applications of Cyanobacteria and Algal Metabolites in Biology, Agriculture and Medicine: Current Status and Future Prospects
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See all 269

Authors: Thomas, N. V., & Kim, S.-K.
Affiliations: Pukyong National University (KR)
Corresponding author: Kim, Se-Kwon
ORCID: Thomas, Noel Vinay
Kim, Se-Kwon
Venue: Environmental Toxicology and Pharmacology
Publisher: Elsevier BV
Published: 2011-11
Volume: 32
Issue: 3
Pages: 325-335
ISSN: 1382-6689 (ISSN-L)
DOI: 10.1016/j.etap.2011.09.004
OpenAlex: W1997545426
Cited by: 269
References: 96
Citations by year: 2026: 5 · 2025: 9 · 2024: 20 · 2023: 26 · 2022: 24 · 2021: 36 · 2020: 21 · 2019: 25 · 2018: 18 · 2017: 16 · 2016: 9 · 2015: 22 · 2014: 10 · 2013: 19 · 2012: 9
FWCI: 1.19
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Environmental Toxicology and Pharmacology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
Keywords: phlorotannins, marine brown algae, polyphenols, Ecklonia cava, Eisenia arborea, Eisenia bicyclis, antioxidant activity, anti-inflammatory activity, antidiabetic activity, anticancer activity, antihypertensive effect, anti-allergic activity, hyaluronidase inhibition, matrix metalloproteinase inhibition, pharmaceutical applications
MeSH terms: Phaeophyceae, Animals, Anti-Inflammatory Agents, Antihypertensive Agents, Antineoplastic Agents, Antioxidants, Enzyme Inhibitors, Humans, Hyaluronoglucosaminidase, Hypoglycemic Agents, Seaweed, Tannins, Anti-Allergic Agents, Anti-HIV Agents, Polyphenols, Matrix Metalloproteinase Inhibitors

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Potential pharmacological applications of polyphenolic derivatives from marine brown algae

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