The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Toxic effects of lead exposure on bioaccumulation, oxidative stress, neurotoxicity, and immune responses in fish: A review
Abstract
Lead (Pb) is a highly toxic metal in aquatic environments. Fish are at the top of the food chain in most aquatic environments, and are the most susceptible to the toxic effects of Pb exposure. In addition, fish are one of the most abundant vertebrates, and they can directly affect humans through food intake; therefore, fish can be used to assess the extent of environmental pollution in an aquatic environment. Pb-induced toxicity in fish exposed to toxicants is primarily induced by bioaccumulation in specific tissues, and the accumulation mechanisms vary depending on water habitat (freshwater or seawater) and pathway (waterborne or dietary exposure). Pb accumulation in fish tissues causes oxidative stress due to excessive ROS production. Oxidative stress by Pb exposure induces synaptic damage and neurotransmitter malfunction in fish as neurotoxicity. Moreover, Pb exposure influences immune responses in fish as an immune-toxicant. Therefore, the purpose of this review was to examine the various toxic effects of Pb exposure, including bioaccumulation, oxidative stress, neurotoxicity, and immune responses, and to identify indicators to evaluate the extent of Pb toxicity by based on the level of Pb exposure.
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Cites
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Cited by
Institute of Biology, P. U. I. S., Tkaczenko, H., Lukash, O., Kamiński, P., & Kurhaluk, N. (2024) · Cellular Physiology and Biochemistry · doi:10.33594/000000716 · Cited by 7
Metadata
- Authors
- Lee, J.-W., Choi, H., Hwang, U.-K., Kang, J.-C., Kang, Y. J., Kim, K. I., & Kim, J.-H.
- Venue
- Environmental Toxicology and Pharmacology
- Publisher
- Elsevier BV
- Published
- 2019-05
- Volume
- 68
- Pages
- 101-108
- ISSN
- 1382-6689 (ISSN-L)
- OpenAlex
- W2922389778
- Cited by
- 523
- References
- 53
- FWCI
- 16.15
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lee, J.-W., Choi, H., Hwang, U.-K., Kang, J.-C., Kang, Y. J., Kim, K. I., & Kim, J.-H. (2019). Toxic effects of lead exposure on bioaccumulation, oxidative stress, neurotoxicity, and immune responses in fish: A review. Environmental Toxicology and Pharmacology. https://doi.org/10.1016/j.etap.2019.03.010
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
