RPE lipofuscin and its role in retinal pathobiology

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Mutation of the Stargardt Disease Gene ( ABCR ) in Age-Related Macular Degeneration

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Identification of the gene responsible for Best macular dystrophy

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Degeneração macular relacionada à idade

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The Role of Oxidative Stress in the Onset and Development of Age-Related Macular Degeneration

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Degeneração macular relacionada à idade e ao sistema purinérgico

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Penta-Modal Imaging Platform with OCT- Guided Dynamic Focusing for Simultaneous Multimodal Imaging

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JoVE Video Dataset

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Autofluoreszenz-Imaging

Fleckenstein, M., Holz, F. G., Pfau, M., & Schmitz-Valckenberg, S. (2023) · Springer Reference Medizin · doi:10.1007/978-3-662-65929-8_38-1

Characterization and contribution of RPE senescence to Age-related macular degeneration in Tnfrsf10 knock out micePreprint

Wada, I., Mori, K., Sreekumar, P. G., Ji, R., Spee, C. K., Hong, E., Ishikawa, K., Sonoda, K., & Kannan, R. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.04.552052

A glance on antioxidants: The role of sulfur amino acids in retinal disorders

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Study of the cytotoxic properties of non-oxidized and oxidized bisretinoids of lipofuscin granules in retinal pigment epithelial cells

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RPE-Phagozytose

Müller, C., & Finnemann, S. C. (2024) · Springer eBooks · doi:10.1007/978-3-031-35055-9_3

Autofluorescence Imaging

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The Vertebrate Retina

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In vitro and in vivo Evaluation of Modulatory Effects of Lutein and Zeaxanthin Supplementation on Retinal Antioxidant and Lipofuscin Levels

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Autofluoreszenz-Imaging

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Multimodal imaging of dark without pressure lesions in paediatric retinal vasculitis: A cross-sectional study

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Inner Retina Changes in ABCA4 -Related Retinopathy: Structure–Function Relationship

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Bisretinoid Lipofuscin in the Retinal Pigment Epithelium: Oxidative Processes and Disease Implications

Sparrow, J. R. (2012) · Humana Press eBooks · doi:10.1007/978-1-61779-606-7_5

Oxidative stress-related damage of retinal pigment epithelial cells : possible protective properties of autophagocytosed iron-binding proteins

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Homozygous initiation codon-altering complex variant causes rapid-onset chorioretinopathy phenotype in ABCA4 disease

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In vivo lipofuscin quantification by visible-light optical coherence tomography-based fundus autofluorescence imaging

Zhou, R., Li, Y., Wen, R., & Jiao, S. (2026) · iScience · doi:10.1016/j.isci.2026.114903

Adaptive Optics Fluorescence Lifetime Imaging Ophthalmoscopy for Single-Cell–Resolved In Vivo Metabolic and Structural Imaging of the Human Retinal Pigment EpitheliumPreprint

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The potential of DNA methylation as a biomarker for age-related macular degeneration: A systematic review

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Genetic Evidence for Causal Effects of Blood Metabolites on Age-Related Macular Degeneration and its Subtypes

Zhang, K., Jia, L., Zhao, C., Wang, Y., Wei, P., & Han, G. (2026) · Translational Vision Science & Technology · doi:10.1167/tvst.15.3.31

Analyse du phénotype visuel d'un modèle de souris déficiente pour la protéine FATP1

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Étude des mécanismes extracellulaires régulant la fonction du récepteur MerTK au cours de la phagocytose rétinienne

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Dégénérescence maculaire liée à l'âge (DMLA) et voie du complément : rôle de la voie alterne du complément dans la pathologie

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Développement d'un modèle cellulaire de la DMLA à partir de cellules de patients pour étudier la physiopathologie de la maladie

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Rôle du facteur H du complément et du récepteur CD47 dans l’inflammation sous-rétinienne

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Questions émergentes dans l'évaluation du risque rétinien des nouvelles technologies d'éclairement domestique : étude expérimentale

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Microenvironment-Driven Modulation of A2E Photoreactivity and Fluorescence Under Blue Light

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From BEST1 mutations to retinal regeneration: integrating stem cell–derived RPE models and gene correction strategies

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Stargardt macular dystrophy

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Update on the Management of ABCA4 Retinopathy (Stargardt Disease)

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Multiphoton Excitation in Retinal Imaging and Functional Measurements

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DGAT1-associated lipid-retinoid dysregulation correlates with metabolic impairment in the RPE of Stargardt disease

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Cellular senescence in posterior segment neovascular diseases: A proposed feed-forward amplification model

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Loss of ABCA4 from photoreceptor discs is associated with glial transcriptomic changes in retinal organoids

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Association Between PS-OCT Derived Polarimetric Entropy and RPE Cellular Metrics Measured With Adaptive Optics Imaging in Retinitis Pigmentosa

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Enhancing lysosome function via TFEB activation reduces lipofuscin-like granules in the retinal pigment epithelium

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Age-Related Changes in bis-Retinoids of Lipofuscin Granules in Human Retinal Pigment Epithelium Cells

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BindingDB Entry 50011319: Development of chiral fluorinated alkyl derivatives of emixustat as drug candidates for the treatment of retinal degenerative diseases.

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Hydroxychloroquine retinopathy: new evidence and recommendations

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Aging human retinal pigment epithelial (RPE) cells accumulate lipofuscin and live on: histological basis of quantitative autofluorescence (AF)

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RPE Lipofuscin

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