The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Variation in the human TP53 gene affects old age survival and cancer mortality
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Citations
Cites
Vogelstein, B., Lane, D., & Levine, A. J. (2000) · Nature · doi:10.1038/35042675 · Cited by 6,607 · cited 1×
“A variety of intracellular stress signals activate p53 to induce either transient cell cycle arrest with stimulation of repair activities, senescence or apoptosis (Vogelstein et al., 2000).”
BackgroundMice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
Donehower, L. A., Harvey, M., Slagle, B. L., McArthur, M. J., Montgomery, C. A., Butel, J. S., & Bradley, A. (1992) · Nature · doi:10.1038/356215a0 · Cited by 4,649
Kirkwood, T. B. L., & Austad, S. N. (2000) · Nature · doi:10.1038/35041682 · Cited by 1,774
p53 mutant mice that display early ageing-associated phenotypes
Tyner, S. D., Venkatachalam, S., Choi, J., Jones, S., Ghebranious, N., Igelmann, H., Lu, X., Soron, G., Cooper, B., Brayton, C., et al. (2002) · Nature · doi:10.1038/415045a · Cited by 1,459 · cited 5×
“0.05. subjects died from general exhaustion and frailty, a human phenotype reminiscent of that described for the p53C/m mice (Tyner et al., 2002).”
BackgroundInfluentialDePinho, R. A. (2000) · Nature · doi:10.1038/35041694 · Cited by 951
Cancer and ageing: rival demons?
Campisi, J. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1073 · Cited by 512 · cited 2×
“The threat posed by genome instability is guarded against by, on the one hand, ‘caretaker’ genes which include genes for DNA repair and are considered longevity assurance genes, and, on the other hand, ‘gatekeeper’ genes which include genes for cell death and cell cycle arrest and are considered tumor suppressor genes…”
BackgroundDoes p53 affect organismal aging?
Donehower, L. A. (2002) · Journal of Cellular Physiology · doi:10.1002/jcp.10104 · Cited by 155
Cited by
Vousden, K. H., & Lane, D. P. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2147 · Cited by 2,272
Stressing the role of FoxO proteins in lifespan and disease
van der Horst, A., & Burgering, B. M. T. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2190 · Cited by 759
p53 polymorphisms: cancer implications
Whibley, C., Pharoah, P. D. P., & Hollstein, M. (2009) · Nature Reviews Cancer · doi:10.1038/nrc2584 · Cited by 665
An overview on the role of dietary phenolics for the treatment of cancers
Anantharaju, P. G., Gowda, P. C., Vimalambike, M. G., & Madhunapantula, S. V. (2016) · Nutrition Journal · doi:10.1186/s12937-016-0217-2 · Cited by 517
Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study
Driver, J. A., Beiser, A., Au, R., Kreger, B. E., Splansky, G. L., Kurth, T., Kiel, D. P., Lu, K. P., Seshadri, S., & Wolf, P. A. (2012) · BMJ · doi:10.1136/bmj.e1442 · Cited by 425
Metadata
- Authors
- van Heemst, D., Mooijaart, S. P., Beekman, M., Schreuder, J., de Craen, A. J. M., Brandt, B. W., Eline Slagboom, P., & Westendorp, R. G. J.
- Venue
- Experimental Gerontology
- Publisher
- Elsevier BV
- Published
- 2005-01
- Volume
- 40
- Issue
- 1-2
- Pages
- 11-15
- ISSN
- 0531-5565 (ISSN-L)
- OpenAlex
- W2037024229
- Cited by
- 206
- References
- 7
- FWCI
- 5.43
- Type
- journal article
- Language
- en
- Open access
- closed
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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- CoChat. (2026). Citation check: Variation in the human TP53 gene affects old age survival and cancer mortality. https://app.cochat.ai/papers/10.1016/j.exger.2004.10.001
- The paper
- van Heemst, D., Mooijaart, S. P., Beekman, M., Schreuder, J., de Craen, A. J. M., Brandt, B. W., Eline Slagboom, P., & Westendorp, R. G. J. (2005). Variation in the human TP53 gene affects old age survival and cancer mortality. Experimental Gerontology. https://doi.org/10.1016/j.exger.2004.10.001
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
