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Overexpression of AtHMA4 enhances root‐to‐shoot translocation of zinc and cadmium and plant metal tolerance

Open access
Verret, Frédéric, Gravot, Antoine, Auroy, Pascaline, Leonhardt, Nathalie, David, Pascale, Nussaume, Laurent, Vavasseur, Alain, Richaud, Pierre·2004·FEBS Letters

Abstract

AtHMA4 is an Arabidopsis thaliana P 1B‐ATPase which transports Zn and Cd. Here, we demonstrate that AtHMA4 is localized at the plasma membrane and expressed in tissues surrounding the root vascular vessels. The ectopic overexpression of AtHMA4 improved the root growth in the presence of toxic concentrations of Zn, Cd and Co. A null mutant exhibited a lower translocation of Zn and Cd from the roots to shoot. In contrast, the AtHMA4 overexpressing lines displayed an increase in the zinc and cadmium shoot content. Altogether, these results strongly indicate that AtHMA4 plays a role in metal loading in the xylem.

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Metadata

Authors
Verret, F., Gravot, A., Auroy, P., Leonhardt, N., David, P., Nussaume, L., Vavasseur, A., & Richaud, P.
Venue
FEBS Letters
Publisher
Wiley
Published
2004-09-25
Volume
576
Issue
3
Pages
306-312
ISSN
  • 0014-5793 (ISSN-L)
  • 1873-3468
OpenAlex
W2003009756
Cited by
556
References
2
FWCI
15.74
Type
journal article
Language
en
Open access
bronze

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Verret, F., Gravot, A., Auroy, P., Leonhardt, N., David, P., Nussaume, L., Vavasseur, A., & Richaud, P. (2004). Overexpression of AtHMA4 enhances root‐to‐shoot translocation of zinc and cadmium and plant metal tolerance. FEBS Letters. https://doi.org/10.1016/j.febslet.2004.09.023

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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