The DOI matches its Crossref record; 51 of the 53 references it cites were found in a registry or an index.
HOXA10 expression is decreased in endometrium of women with adenomyosis
Open accessAbstract
HOXA10 gene expression is decreased in the secretory phase endometrium of women with adenomyosis. Diminished expression of HOXA10 is a potential mechanism explaining decreased implantation observed in women with adenomyosis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The endometrial transcriptome in women with endometriosis may have shared patterns of dysregulation with other inflammatory conditions such as hydrosalpinx [110] or other estrogen dependent diseases such as leiomyomata, endometrial polyps, or adenomyosis [111, 112].”
From Update on biomarkers for the detection of endometriosis (2015) · cites this paper as [112]
In the citing paper
“In addition to menstrual cycle phase, gynecologic conditions other than endometriosis have been shown to influence eutopic endometrial gene and protein expression.”
From Update on biomarkers for the detection of endometriosis (2015) · cites this paper as [112]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Effect of endometriosis on in vitro fertilization
Barnhart, K. T., Dunsmoor-Su, R. F., & Coutifaris, C. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(02)03112-6 · Cited by 805 · cited 1×
“Women with endometriosis have lower implantation rates (42).”
Cohabitation, marriage, divorce, and remarriage in the United States
Bramlett, M. D., & Mosher, W. D. (2002) · PsycEXTRA Dataset · doi:10.1037/e372462004-001 · Cited by 570
Taylor, H. S., Arici, A. M., Olive, D. L., & Igarashi, P. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1057 · Cited by 555
Self-citationThe elusive adenomyosis of the uterus—revisited
Bird, C. C., McElin, T. W., & Manalo-Estrella, P. (1972) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(72)90781-8 · Cited by 531 · cited 1×
“Approximately 35% of women with adenomyosis are asymptomatic (4).”
Sexually dimorphic sterility phenotypes in HoxalO-deficient mice
Satokata, I., Benson, G., & Maas, R. L. (1995) · Nature · doi:10.1038/374460a0 · Cited by 519
Aberrant integrin expression in the endometrium of women with endometriosis
Lessey, B. A., Castelbaum, A. J., Sawin, S. W., Buck, C. A., Schinnar, R., Bilker, W. B., & Strom, B. L. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.79.2.7519194 · Cited by 514 · cited 1×
“Intensity of HOXA10 nuclear staining is indicated by a value of 0, 1, 2, or 3 (none, weak, moderate, strong), and Pi is the percentage of stained nuclei for each intensity (33, 34).”
Taylor, H. S., Vanden Heuvel, G. B., & Igarashi, P. (1997) · Biology of Reproduction · doi:10.1095/biolreprod57.6.1338 · Cited by 463 · cited 1×
“In endometriosis, a condition commonly seen with adenomyosis, HOXA10 expression does not increase normally during the midsecretory phase (15).”
Self-citationTaylor, H. S., Arici, A. M., Olive, D. L., & Igarashi, P. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1597 · Cited by 420
Self-citationHOX gene expression is altered in the endometrium of women with endometriosis
Taylor, H. S. (1999) · Human Reproduction · doi:10.1093/humrep/14.5.1328 · Cited by 376 · cited 1×
“Decreased expression of HOXA10 during the midsecretory phase of themenstrual cycle is seen in other conditions associatedwith impaired implantation, such as PCOS, submucosal uterine leiomyomas, hydrosalphinx, and endometriosis (28, 29, 30, 31, 35).”
Self-citationEndocrine Regulation of HOX Genes
Daftary, G. S., & Taylor, H. S. (2006) · Endocrine Reviews · doi:10.1210/er.2005-0018 · Cited by 344
Self-citation
Research works printed but not linked: 1
- Bagot, 2000, Alteration of maternal Hoxa10 expression by in vivo gene transfection affects implantation, Gene Ther, 7, 1378, 10.1038/sj.gt.3301245 · DOI
Cited by
Sorted by citations
Physiological and molecular determinants of embryo implantation
Zhang, S., Lin, H., Kong, S., Wang, S., Wang, H., Wang, H., & Armant, D. R. (2013) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.12.011 · Cited by 598
Vannuccini, S., Clifton, V. L., Fraser, I. S., Taylor, H. S., Critchley, H., Giudice, L. C., & Petraglia, F. (2016) · Human Reproduction Update · doi:10.1093/humupd/dmv044 · Cited by 379
“The same mechanisms may affect decidual/trophoblast invasion in women with adenomyosis, who showed increased expression of MMP-2 and MMP-9, E-cadherin, HOXA-10 and leukemia inhibitory factor (Fischer et al., 2011; Benagiano et al., 2012; Galliano et al., 2015; Fig.”
BackgroundSelf-citationPathogenesis of adenomyosis, an update on molecular mechanisms
Vannuccini, S., Tosti, C., Carmona, F., Huang, S. J., Chapron, C., Guo, S.-W., & Petraglia, F. (2017) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2017.06.016 · Cited by 326
“…implantation-associated factors, such as HOXA10, LIF, MMP2, IL-6, cytochrome P450 and RCAS1, in the eutopic endometrium in women with adenomyosis leads to reduced endometrial receptivity and impaired decidualization (Campo et al., 2012b; Fischer et al., 2011; Xishi et al., 2010; Zhou et al., 2012).”
Endometriosis-associated infertility: From pathophysiology to tailored treatment
Bonavina, G., & Taylor, H. S. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1020827 · Cited by 388
Self-citationAdenomyosis: Mechanisms and Pathogenesis
Zhai, J., Vannuccini, S., Petraglia, F., & Giudice, L. C. (2020) · Seminars in Reproductive Medicine · doi:10.1055/s-0040-1716687 · Cited by 331
Metadata
- Authors
- Fischer, C. P., Kayisili, U., & Taylor, H. S.
- Affiliations
- Yale University (US)
- Corresponding author
- Taylor, Hugh S.
- ORCID
- Taylor, Hugh S.
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2011-03
- Volume
- 95
- Issue
- 3
- Pages
- 1133-1136
- ISSN
- 0015-0282 (ISSN-L)
- PMC
- PMC3053130
- OpenAlex
- W2165954066
- Cited by
- 133
- References
- 53
- Citations by year
- 2026: 8 · 2025: 8 · 2024: 18 · 2023: 6 · 2022: 17 · 2021: 11 · 2020: 8 · 2019: 9 · 2018: 6 · 2017: 8 · 2016: 8 · 2015: 6 · 2014: 8 · 2013: 5 · 2012: 4
- FWCI
- 4.55
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (U54HD052668, R01HD036887)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Keywords
- HOXA10, adenomyosis, endometrium, luteal phase, gene expression, implantation failure, endometrial receptivity
- MeSH terms
- Homeobox A10 Proteins, Adult, Biopsy, Endometriosis, Endometrium, Female, Humans, Immunohistochemistry, Infertility, Female, Middle Aged, Embryo Implantation, Case-Control Studies, Homeodomain Proteins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
