T helper (Th)1, Th2, and Th17 interleukin pathways in infertile patients with minimal/mild endometriosis
Open accessAbstract
In the present study, interleukin (IL)-10, IL-12, IL-17, and IL-23 levels were measured in serum and peritoneal fluid of women with minimal or mild endometriosis and compared with levels in controls without endometriosis. Higher IL-23 levels were encountered in the peritoneal fluid of women with endometriosis, suggesting a possible role of this cytokine in these women's infertility.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Values of T-helper pathway related interleukins IL-10, IL-12, IL-17, and IL-23 levels were comparable between infertile controls and endometriosis patients with infertility.
“Values of T-helper pathway related interleukins IL-10, IL-12, IL-17, and IL-23 levels were comparable between infertile controls and endometriosis patients with infertility [49].”
From Update on biomarkers for the detection of endometriosis (2015) · cites this paper as [49]
Cites
1 retracted
Doreau, A., Bélot, A., Bastid, J., Riche, B., Trescol-Biémont, M.-C., Ranchin, B., Fabien, N., Cochat, P., Pouteil‐Noble, C., Trolliet, P., et al. (2009) · Nature Immunology · doi:10.1038/ni.1741 · Cited by 448 · see citing works
RetractedRevised American Society for Reproductive Medicine classification of endometriosis: 1996
American Society for Reproductive Medicine (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)81391-x · Cited by 3,018 · see citing works
McConnell, J. M. L., Shelley, P., Heales, S., John, C., Jensen, R. I., Khan, I. Y., Taylor, P. D., & Poston, L. (2005) · Cited by 1,235 · see citing works
The IL-23/IL-17 axis in inflammation
Iwakura, Y. (2006) · Journal of Clinical Investigation · doi:10.1172/jci28508 · Cited by 1,046 · see citing works
Bulletti, C., Coccia, M. E., Battistoni, S., & Borini, A. (2010) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-010-9436-1 · Cited by 776 · see citing works
Olive, D. L., & Schwartz, L. B. (1993) · New England Journal of Medicine · doi:10.1056/nejm199306173282407 · Cited by 675 · see citing works
Sinaii, N. (2002) · Human Reproduction · doi:10.1093/humrep/17.10.2715 · Cited by 620 · see citing works
Role of cytokines in endometriosis
Harada, T., Iwabe, T., & Terakawa, N. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(01)01816-7 · Cited by 567 · see citing works
Prediction of endometriosis with serum and peritoneal fluid markers: a prospective controlled trial
Bedaiwy, M. A. (2002) · Human Reproduction · doi:10.1093/humrep/17.2.426 · Cited by 485 · see citing works
Role of Th17 cells in human autoimmune arthritis
Leipe, J., Grünke, M., Dechant, C., Reindl, C., Kerzendorf, U., Schulze‐Koops, H., & Skapenko, A. (2010) · Arthritis & Rheumatism · doi:10.1002/art.27622 · Cited by 448 · see citing works
The epidemiology of endometriosis
Missmer, S. A., & Cramer, D. W. (2003) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/s0889-8545(02)00050-5 · Cited by 385 · see citing works
Endometriosis: an inflammatory disease with a Th2 immune response component
Podgaec, S., Abrão, M. S., Dias, J., Rizzo, L. V., de Oliveira, R. M., & Baracat, E. C. (2007) · Human Reproduction · doi:10.1093/humrep/del516 · Cited by 279 · see citing works
Treating endometriosis as an autoimmune disease
Nothnick, W. B. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(01)01878-7 · Cited by 270 · see citing works
Berkkanoğlu, M., & Arici, A. M. (2003) · American Journal of Reproductive Immunology · doi:10.1034/j.1600-0897.2003.00042.x · Cited by 240 · see citing works
Nogueira, E., Hamour, S., Sawant, D., Henderson, S. R., Mansfield, N., Chavele, K.-M., Pusey, C. D., & Salama, A. D. (2010) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfp783 · Cited by 234 · see citing works
Cantab, M. D. (1972) · PubMed · Cited by 222 · see citing works
The Role of Endometrium in Endometriosis
Ulukuş, M., Çakmak, H., & Arici, A. M. (2006) · Journal of the Society for Gynecologic Investigation · doi:10.1016/j.jsgi.2006.07.005 · Cited by 171 · see citing works
Cytokines and Cytokine Profiles in Human Autoimmune Diseases and Animal Models of Autoimmunity
Kunz, M., & Ibrahim, S. M. (2009) · Mediators of Inflammation · doi:10.1155/2009/979258 · Cited by 171 · see citing works
The endometrium versus embryonic quality in endometriosis-related infertility
Garrido, N. (2002) · Human Reproduction Update · doi:10.1093/humupd/8.1.95 · Cited by 166 · see citing works
Wardle, P. G., McLaughlin, E. A., McDermott, A., Mitchell, J. D., Ray, B. D., & Hull, M. G. R. (1985) · The Lancet · doi:10.1016/s0140-6736(85)90289-2 · Cited by 165 · see citing works
The link between IL-23 and Th17 cell-mediated immune pathologies
McGeachy, M. J., & Cua, D. J. (2007) · Seminars in Immunology · doi:10.1016/j.smim.2007.10.012 · Cited by 151 · see citing works
Hirata, T., Osuga, Y., Hamasaki, K., Yoshino, O., Ito, M., Hasegawa, A., Takemura, Y., Hirota, Y., Nose, E., Morimoto, C., et al. (2007) · Endocrinology · doi:10.1210/en.2007-0749 · Cited by 144 · see citing works
Potential role of Th17 cells in the pathogenesis ofinflammatory bowel disease
Liu, Z., Yadav, P. K., Su, J., Wang, J.-S., & Fei, K. (2009) · World Journal of Gastroenterology · doi:10.3748/wjg.15.5784 · Cited by 142 · see citing works
Is endometriosis an endometrial disease?
Vinatier, D., Cosson, M., & Dufour, P. (2000) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/s0301-2115(99)00263-8 · Cited by 115 · see citing works
Lemos, N. A., Arbo, E., Scalco, R., Weiler, E., Rosa, V., & Cunha-Filho, J. S. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.04.048 · Cited by 110 · see citing works
Self-citationZhang, X., Xu, H., Lin, J., Qian, Y., & Deng, L. (2005) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2005.00639.x · Cited by 90 · see citing works
Thyroid autoimmunity and thyroid dysfunction in women with endometriosis
Petta, C. A., Arruda, M. S., Zantut‐Wittmann, D. E., & Benetti‐Pinto, C. L. (2007) · Human Reproduction · doi:10.1093/humrep/dem267 · Cited by 74 · see citing works
Doody, M. C., Gibbons, W. E., & Buttram, V. C. (1988) · Fertility and Sterility · doi:10.1016/s0015-0282(16)59646-0 · Cited by 73 · see citing works
New advances in the understanding of endometriosis related infertility
MAHUTTE, N. G., & Arici, A. M. (2002) · Journal of Reproductive Immunology · doi:10.1016/s0165-0378(01)00130-9 · Cited by 69 · see citing works
Interleukin-12 but not interleukin-18 is associated with severe endometriosis
de Oliveira, F. F. L., Abrão, M. S., Podgaec, S., Dias, J., de Oliveira, R. M., & Rizzo, L. V. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.11.060 · Cited by 63 · see citing works
Future directions in endometriosis research
D’Hooghe, T. M., Debrock, S., Meuleman, C., Hill, J. A., & Mwenda, J. M. (2003) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/s0889-8545(02)00063-3 · Cited by 59 · see citing works
Pasoto, S. G., Abrão, M. S., Viana, V. S. T., Bueno, C., Leon, E. P., & Bonfá, E. (2005) · American Journal of Reproductive Immunology · doi:10.1111/j.1600-0897.2005.00252.x · Cited by 53 · see citing works
Gallinelli, A., Chiossi, G., Giannella, L., Marsella, T., Genazzani, A. D., & Volpe, A. (2004) · Gynecological Endocrinology · doi:10.1080/09513590310001653044 · Cited by 51 · see citing works
Senturk, L. M., & Arici, A. M. (1999) · Journal of Reproductive Immunology · doi:10.1016/s0165-0378(98)00079-5 · Cited by 51 · see citing works
Cunha‐Filho, J. S., Gross, J. L., Lemos, N. A., Brandelli, A., Castillos, M., & Passos, E. P. (2001) · Hormone and Metabolic Research · doi:10.1055/s-2001-14945 · Cited by 50 · see citing works
Self-citationMinimal/mild endometriosis and infertility. A review
Bancroft, K., WILLIAMS, C. A. V., & Elstein, M. (1989) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1989.tb02422.x · Cited by 48 · see citing works
Cunha‐Filho, J. S., Gross, J. L., de Souza, C. A. B., et al. (2003) · Journal of Assisted Reproduction and Genetics · doi:10.1023/a:1022625106489 · Cited by 48 · see citing works
Self-citationCunha‐Filho, J. S. (2002) · Human Reproduction · doi:10.1093/humrep/17.4.960 · Cited by 29 · see citing works
Self-citationGlitz, C. L., de Souza, C. A. B., Rodini, G. P., et al. (2009) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2009001100007 · Cited by 21 · see citing works
Self-citationGazvani, R., Bates, M. D., Vince, G. S., Christmas, S. E., Lewis‐Jones, I., & Kingsland, C. R. (2001) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1034/j.1600-0412.2001.080002175.x · Cited by 16 · see citing works
Minimal/mild endometriosis and infertility
Mahmood, T. A., & Templeton, A. A. (1989) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.1989.tb03215.x · Cited by 15 · see citing works
Seery, J. P. (2006) · Medical Hypotheses · doi:10.1016/j.mehy.2005.11.032 · Cited by 14 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Update on biomarkers for the detection of endometriosis
Fassbender, A., Burney, R. O., F. O, D., D’Hooghe, T., & Giudice, L. (2015) · BioMed Research International · doi:10.1155/2015/130854 · Cited by 195 · see citing works
“interleukins IL-10, IL-12, IL-17, and IL-23 levels were comparable between infertile controls and endometriosis patients with infertility [49].”
Endometriosis: where are we and where are we going?
Greene, A. D., Lang, S. A., Kendziorski, J. A., Sroga-Rios, J. M., Herzog, T. J., & Burns, K. A. (2016) · Reproduction · doi:10.1530/rep-16-0052 · Cited by 187 · see citing works
- Authors
- Andreoli, C. G., Genro, V. K., Souza, C. A., Michelon, T., Bilibio, J. P., Scheffel, C., & Cunha-Filho, J. S.
- Affiliations
- Universidade Federal do Rio Grande do Sul (BR)
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2011-06
- Volume
- 95
- Issue
- 8
- Pages
- 2477-2480
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2154580647
- Cited by
- 68
- References
- 42
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 15 · 2023: 6 · 2022: 7 · 2021: 5 · 2020: 2 · 2019: 6 · 2018: 5 · 2017: 2 · 2016: 6 · 2015: 4 · 2014: 1 · 2013: 1 · 2012: 3
- FWCI
- 1.79
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
- Keywords
- endometriosis, infertility, Th1/Th2/Th17 balance, IL-10, IL-12, IL-17, IL-23, peritoneal fluid, serum cytokines
- MeSH terms
- Adult, Ascitic Fluid, Brazil, Cross-Sectional Studies, Endometriosis, Enzyme-Linked Immunosorbent Assay, Female, T-Lymphocytes, Helper-Inducer, Humans, Infertility, Female, Peritoneal Diseases, Laparoscopy, Severity of Illness Index, Biomarkers, Up-Regulation, Case-Control Studies, Interleukin-10, Th1 Cells, Th2 Cells, Interleukin-12, Interleukin-17, Interleukin-23, Th17 Cells
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review