Cited by 42Cardiac Ischemia and ReperfusionPhytochemicals and Medicinal PlantsMedicinal Plant Research

Cardioprotective effect of ‘Marutham’a polyherbal formulation on isoproterenol induced myocardial infarction in Wistar rats

Prince, Ponnian Stanely Mainzen, Suman, Selvaraju, Devika, Periyathambi Thangappan, Vaithianathan, Muthukumarasamy·2008·Fitoterapia

Abstract

Myocardial infarction is the number one killer disease in many parts of the world. The cardioprotective effect of Marutham, a polyherbal formulation on serum and heart tissue lipids, serum lipoproteins and heart membrane bound enzymes in isoproterenol induced myocardial infarction was studied in Wistar rats. Pretreatment with Marutham at different doses of 30, 60 and 90 mg kg(-1) to isoproterenol treated rats significantly prevented the altered lipid profile and membrane bound enzymes to near normal status. The results of our study showed the cardioprotective potential of Marutham on isoproterenol induced myocardial infarction in rats.

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Crossref · 10.1016/j.fitote.2008.01.009

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Authors
Prince, P. S. M., Suman, S., Devika, P. T., & Vaithianathan, M.
Affiliations
Annamalai University (IN)
Corresponding author
Prince, Ponnian Stanely Mainzen
Venue
Fitoterapia
Publisher
Elsevier BV
Published
2008-09
Volume
79
Issue
6
Pages
433-438
ISSN
0367-326X (ISSN-L)
OpenAlex
W2002742222
Cited by
42
References
21
Citations by year
2026: 1 · 2025: 2 · 2024: 5 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 3 · 2017: 3 · 2016: 4 · 2015: 2 · 2014: 2 · 2013: 6 · 2012: 2
FWCI
1.66
Type
journal article
Language
en
Open access
closed
Locations
  • Fitoterapia (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Cardiac Ischemia and Reperfusion
  • Health Sciences › Medicine › Complementary and alternative medicine › Phytochemicals and Medicinal Plants
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
Keywords
polyherbal formulation, cardioprotection, myocardial infarction, isoproterenol-induced cardiotoxicity, serum lipids, lipoproteins, herbal medicine
MeSH terms
Animals, Cardiotonic Agents, Hyperlipidemias, Isoproterenol, Lipids, Lipoproteins, Male, Phytotherapy, Membrane Proteins, Myocardial Infarction, Myocardium, Rats, Wistar, Plant Preparations, Rats, Plant Exudates

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