The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.
Antioxidant and free radical scavenging potential of Achillea santolina extracts
Open accessAbstract
Abstract The antioxidative activities of hydroalcoholic extract of Achillea santolina were investigated employing various established in vitro systems including total antioxidant activity in linoleic acid emulsion system, 1,1-diphenyl-2-picrylhydrazyl (DPPH), superoxide and hydroxyl radicals scavenging, reducing power, and inhibitory effect on protein oxidation as well as the inhibition of Fe 2+ /ascorbate induced lipid peroxidation in rat liver homogenate. Total phenolic and flavonoid content of A. santolina extract (ASE) was also determined by a colorimetric method. The results revealed that ASE has notable inhibitory activity on peroxides formation in linoleic acid emulsion system along with concentration-dependent quenching of DPPH and superoxide radicals. Furthermore, the extract showed both nonsite-specific (Fe 2+ + H 2 O 2 + EDTA) and site-specific (Fe 2+ + H 2 O 2 ) hydroxyl radical scavenging suggesting potent hydroxyl radical scavenging and chelating ability for iron ions in deoxyribose degradation model. A linear correlation between ASE and the reducing power was also observed ( r 2 = 0.9981). ASE prevents thiobarbituric acid reactive substances formation in Fe 2+ /ascorbate induced lipid peroxidation in rat liver tissue in a dose-dependent manner. Moreover, free radical induced protein oxidation was suppressed significantly by the addition of ASE over a range of concentration. These results clearly demonstrated that A. santolina extract possess a marked antioxidant activity.
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Cited by
Singh, B. N., Singh, B. R., Singh, R. L., Prakash, D., Dhakarey, R., Upadhyay, G., & Singh, H. B. (2009) · Food and Chemical Toxicology · doi:10.1016/j.fct.2009.01.034 · Cited by 425
Gharibi, S., Tabatabaei, B. E. S., Saeidi, G., & Goli, S. A. H. (2016) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-015-1909-3 · Cited by 272
Singh, B. N., Singh, B. R., Singh, R. L., Prakash, D., Singh, D. P., Sarma, B. K., Upadhyay, G., & Singh, H. B. (2009) · Food and Chemical Toxicology · doi:10.1016/j.fct.2009.02.004 · Cited by 268
Antioxidant Activity and Hepatoprotective Effects of Whey Protein and Spirulina in Rats
Gad, A. S., Khadrawy, Y. A., El-Nekeety, A. A., Mohamed, S. R., Hassan, N. S., & Abdel-Wahhab, M. A. (2011) · Nutrition · doi:10.1016/j.nut.2010.04.002 · Cited by 218
Song, J., Li, D., Liu, C., & Zhang, Y. (2011) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2011.03.001 · Cited by 115
Metadata
- Authors
- Ardestani, A., & Yazdanparast, R.
- Venue
- Food Chemistry
- Publisher
- Elsevier BV
- Published
- 2007-01
- Volume
- 104
- Issue
- 1
- Pages
- 21-29
- ISSN
- 0308-8146 (ISSN-L)
- OpenAlex
- W2012021375
- Cited by
- 390
- References
- 50
- FWCI
- 6.10
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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