Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo

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S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression

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Caffeic acid, a phyto polyphenol mitigates fluoride induced hepatotoxicity in rats: A possible mechanism

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A far-upstream AP-1/Smad binding box regulates human NOX4 promoter activation by transforming growth factor-β

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Increased Expression of NAPDH Oxidase 4 in Systemic Sclerosis Dermal Fibroblasts: Regulation by Transforming Growth Factor β

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Primary biliary cholangitis as a roadmap for the development of novel treatments for cholestatic liver diseases†

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Liver Fibrosis and Protection Mechanisms Action of Medicinal Plants Targeting Apoptosis of Hepatocytes and Hepatic Stellate Cells

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The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice

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Polydatin protects against carbon tetrachloride-induced liver fibrosis in mice

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Upstream Regulators and Downstream Effectors of NADPH Oxidases as Novel Therapeutic Targets for Diabetic Kidney Disease

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Plumbagin Ameliorates Diabetic Nephropathy via Interruption of Pathways that Include NOX4 Signalling

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Role of redoximiRs in fibrogenesis

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Dysregulation of redox pathways in liver fibrosis

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Novel Therapeutic Targets in Liver Fibrosis

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Novel Therapeutic Approaches to Liver Fibrosis Based on Targeting Oxidative Stress

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Current investigations for liver fibrosis treatment: between repurposing the FDA-approved drugs and the other emerging approaches

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Ursolic acid reverses liver fibrosis by inhibiting interactive NOX4/ROS and RhoA/ROCK1 signalling pathways

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Fibroblast growth factor 18 alleviates stress-induced pathological cardiac hypertrophy in male mice

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Nox4 as a potential therapeutic target for treatment of uremic toxicity associated to chronic kidney disease

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Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice

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Interaction Mechanisms Between the NOX4/ROS and RhoA/ROCK1 Signaling Pathways as New Anti- fibrosis Targets of Ursolic Acid in Hepatic Stellate Cells

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Fuzheng Huayu recipe alleviates hepatic fibrosis via inhibiting TNF-α induced hepatocyte apoptosis

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The Apelin–Apelin Receptor Axis Triggers Cholangiocyte Proliferation and Liver Fibrosis During Mouse Models of Cholestasis

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Aucubin ameliorates liver fibrosis and hepatic stellate cells activation in diabetic mice via inhibiting ER stress-mediated IRE1α/TXNIP/NLRP3 inflammasome through NOX4/ROS pathway

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Scoparone attenuates hepatic stellate cell activation through inhibiting TGF-β/Smad signaling pathway

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NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4

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Clinical Management of Primary Biliary Cholangitis—Strategies and Evolving Trends

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Decursin attenuates hepatic fibrogenesis through interrupting TGF-beta-mediated NAD(P)H oxidase activation and Smad signaling in vivo and in vitro

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Heme oxygenase-1 derived carbon monoxide suppresses Aβ1–42 toxicity in astrocytes

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When healing turns into killing – the pathophysiology of pancreatic and hepatic fibrosis

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NADPH oxidase 4 is dispensable for skin myofibroblast differentiation and wound healing

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Inhibitory Effect of Sestrin 2 on Hepatic Stellate Cell Activation and Liver Fibrosis

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The Role of Vitamin D in Autoimmune Hepatitis

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The TGF-β/NADPH Oxidases Axis in the Regulation of Liver Cell Biology in Health and Disease

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Forsythiaside A Regulates Activation of Hepatic Stellate Cells by Inhibiting NOX4‐Dependent ROS

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Long non-coding RNA H19, a negative regulator of microRNA-148b-3p, participates in hypoxia stress in human hepatic sinusoidal endothelial cells via NOX4 and eNOS/NO signaling

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CSF‐1 in Osteocytes Inhibits Nox4‐mediated Oxidative Stress and Promotes Normal Bone Homeostasis

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Protein tyrosine phosphatase 1b deficiency protects against hepatic fibrosis by modulating nadph oxidases

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NOX1 inhibition attenuates the development of a pro‐tumorigenic environment in experimental hepatocellular carcinoma

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Nature and Implications of Oxidative and Nitrosative Stresses in Autoimmune Hepatitis

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NADPH Oxidase 1 and NADPH Oxidase 4 Have Opposite Prognostic Effects for Patients with Hepatocellular Carcinoma after Hepatectomy

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Effects and potential mechanisms of IGF1/IGF1R in the liver fibrosis: A review

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Targeting Hepatic Fibrosis in Autoimmune Hepatitis

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Globular adiponectin protects hepatocytes from tunicamycin-induced cell death via modulation of the inflammasome and heme oxygenase-1 induction

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Hydrogen Sulfide: A Therapeutic Candidate for Fibrotic Disease?

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Plumbagin ameliorates liver fibrosis via a ROS-mediated NF-кB signaling pathway in vitro and in vivo

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New Therapeutic Targets in Autoimmune Cholangiopathies

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Novel insights into alcoholic liver disease: Iron overload, iron sensing and hemolysis

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Nox1 downregulators: A new class of therapeutics

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NADPH oxidase 4 (Nox4) deletion accelerates liver regeneration in mice

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Hearing vulnerability after noise exposure in a mouse model of reactive oxygen species overproduction

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Current drugs in early development for treating hepatitis C virus-related hepatic fibrosis

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Molecular Mechanism Pathways of Natural Compounds for the Treatment of Non-Alcoholic Fatty Liver Disease

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The role of endoglin in kidney fibrosis

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NOX4 Regulates CCR2 and CCL2 mRNA Stability in Alcoholic Liver Disease

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Acute Changes in NADPH Oxidase 4 in Early Post‐Traumatic Osteoarthritis

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Fibroproliferative disorders and diabetes: Understanding the pathophysiologic relationship between Peyronie’s disease, Dupuytren disease and diabetes

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Hepatoprotective effect of vitamin C on lithocholic acid-induced cholestatic liver injury in Gulo(−/−) mice

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Setanaxib mitigates oxidative damage following retinal ischemia-reperfusion via NOX1 and NOX4 inhibition in retinal ganglion cells

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Review article: next‐generation transformative advances in the pathogenesis and management of autoimmune hepatitis

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NOX4 inhibition promotes the remodeling of dystrophic muscle

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Cellular heterogeneity and plasticity during NAFLD progression

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Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population

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Redox mechanisms in pathological angiogenesis in the retina: roles for NADPH oxidase

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Pathways Linking Nicotinamide Adenine Dinucleotide Phosphate Production to Endoplasmic Reticulum Protein Oxidation and Stress

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NADPH oxidase 4 is protective and not fibrogenic in intestinal inflammation

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Bone marrow mononuclear cell transplantation improves mitochondrial bioenergetics in the liver of cholestatic rats

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Mechanism of the Regulatory Effect of Overexpression of circMTO1 on Proliferation and Apoptosis of Hepatoma Cells via miR-9-5p/NOX4 Axis

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NADPH oxidase 1 is a novel pharmacological target for the development of an antiplatelet drug without bleeding side effects

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Characterisation of Nox4 Inhibitors from Edible Plants

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Inflammasome as an Effective Platform for Fibrosis Therapy

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miR‐322 treatment rescues cell apoptosis and neural tube defect formation through silencing NADPH oxidase 4

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Primary biliary cholangitis and the narrowing gap towards optimal disease control

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