Brandes, Ralf P.

Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

Heumüller, S., Wind, S., Barbosa-Sicard, E., Schmidt, H. H. H. W., Busse, R., Schröder, K., & Brandes, R. P. (2008) · Hypertension

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 735

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

Schröder, K., Zhang, M., Benkhoff, S., Mieth, A., Pliquett, R., Kosowski, J., Kruse, C., Luedike, P., Michaelis, U. R., Weissmann, N., et al. (2012) · Circulation Research

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 622

A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial Wall

Görlach, A., Brandes, R. P., Nguyen, K., Amidi, M., Dehghani, F., & Busse, R. (2000) · Circulation Research

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 598

Endothelial aging

BRANDES, R., FLEMING, I., & BUSSE, R. (2005) · Cardiovascular Research

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 563

Direct Interaction of the Novel Nox Proteins with p22phox Is Required for the Formation of a Functionally Active NADPH Oxidase

Ambasta, R. K., Kumar, P., Griendling, K. K., Schmidt, H. H. H. W., Busse, R., & Brandes, R. P. (2004) · Journal of Biological Chemistry

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 541

Endothelium-Derived Hyperpolarizing Factor Synthase (Cytochrome P450 2C9) Is a Functionally Significant Source of Reactive Oxygen Species in Coronary Arteries

Fleming, I., Michaelis, U. R., Bredenkötter, D., Fisslthaler, B., Dehghani, F., Brandes, R. P., & Busse, R. (2001) · Circulation Research

Eicosanoids and Hypertension PharmacologyNitric Oxide and Endothelin Effects

Cited by 440

Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo

Jiang, J. X., Chen, X., Serizawa, N., Szyndralewiez, C., Page, P., Schröder, K., Brandes, R. P., Devaraj, S., & Török, N. J. (2012) · Free Radical Biology and Medicine

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 251

Extracellular Superoxide Dismutase Is a Major Determinant of Nitric Oxide Bioavailability: In Vivo and Ex Vivo Evidence From ecSOD-Deficient Mice

Jung, O., Marklund, S. L., Geiger, H., Pedrazzini, T., Busse, R., & Brandes, R. P. (2003) · Circulation Research

Nitric Oxide and Endothelin EffectsEicosanoids and Hypertension Pharmacology

Cited by 223

Identification of Structural Elements in Nox1 and Nox4 Controlling Localization and Activity

Helmcke, I., Heumüller, S., Tikkanen, R., Schröder, K., & Brandes, R. P. (2009) · Antioxidants & Redox Signaling

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 145

Which NADPH Oxidase Isoform Is Relevant for Ischemic Stroke? The Case for Nox 2

Kahles, T., & Brandes, R. P. (2013) · Antioxidants & Redox Signaling

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 125

Role of Increased Production of Superoxide Anions by NAD(P)H Oxidase and Xanthine Oxidase in Prolonged Endotoxemia

Brandes, R. P., Koddenberg, G., Gwinner, W., Kim, D.-Y., Kruse, H.-J., Busse, R., & Mügge, A. (1999) · Hypertension

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 122

Targeting inflammation and oxidative stress in atrial fibrillation: role of 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibition with statins

Pinho-Gomes, A. C., Reilly, S., Brandes, R. P., & Casadei, B. (2014) · Antioxidants & Redox Signaling

Atrial Fibrillation Management and OutcomesCardiac electrophysiology and arrhythmias

Cited by 94

NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice

Kahles, T., Kohnen, A., Heumueller, S., Rappert, A., Bechmann, I., Liebner, S., Wittko, I. M., Neumann-Haefelin, T., Steinmetz, H., Schroeder, K., et al. (2010) · Neurobiology of Disease

Acute Ischemic Stroke ManagementNeuroprotection in Cerebral Ischemia

Cited by 91

Triggering Mitochondrial Radical Release: A New Function for NADPH Oxidases

Brandes, R. P. (2005) · Hypertension

Mitochondrial Function and PathologyNitric Oxide and Endothelin Effects

Cited by 79

Roadmap for alleviating the manifestations of ageing in the cardiovascular system

Liberale, L., Tual-Chalot, S., Sedej, S., Ministrini, S., Georgiopoulos, G., Grunewald, M., Bäck, M., Bochaton-Piallat, M.-L., Boon, R. A., Ramos, G. C., et al. (2025) · Nature Reviews Cardiology

Cardiovascular Health and Disease PreventionTelomeres, Telomerase, and Senescence

Cited by 59

The polarity protein Scrib is essential for directed endothelial cell migration

Michaelis, U. R., Chavakis, E., Kruse, C., Jungblut, B., Kaluza, D., Wandzioch, K., Manavski, Y., Heide, H., Santoni, M.-J., Potente, M., et al. (2013) · Circulation Research

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 57

Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays

Rezende, F., Prior, K.-K., Löwe, O., Wittig, I., Strecker, V., Moll, F., Helfinger, V., Schnütgen, F., Kurrle, N., Wempe, F., et al. (2017) · Free Radical Biology and Medicine

Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 46

DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells

Seredinski, S., Boos, F., Günther, S., Oo, J. A., Warwick, T., Izquierdo Ponce, J., Lillich, F. F., Proschak, E., Knapp, S., Gilsbach, R., et al. (2022) · Molecular Therapy Nucleic Acids

Cancer therapeutics and mechanismsCancer-related molecular mechanisms research

Cited by 21

Incidence of microvascular dysfunction is increased in hyperlipidemic mice, reducing cerebral blood flow and impairing remote memory

Hernandez Torres, L. D., Rezende, F., Peschke, E., Will, O., Hövener, J.-B., Spiecker, F., Özorhan, Ü., Lampe, J., Stölting, I., Aherrahrou, Z., et al. (2024) · Frontiers in Endocrinology

Neurological Disease Mechanisms and TreatmentsBarrier Structure and Function Studies

Cited by 8