The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Cellular metabolic and autophagic pathways: Traffic control by redox signaling
Open accessAbstract
It has been established that the key metabolic pathways of glycolysis and oxidative phosphorylation are intimately related to redox biology through control of cell signaling. Under physiological conditions glucose metabolism is linked to control of the NADH/NAD redox couple, as well as providing the major reductant, NADPH, for thiol-dependent antioxidant defenses. Retrograde signaling from the mitochondrion to the nucleus or cytosol controls cell growth and differentiation. Under pathological conditions mitochondria are targets for reactive oxygen and nitrogen species and are critical in controlling apoptotic cell death. At the interface of these metabolic pathways, the autophagy-lysosomal pathway functions to maintain mitochondrial quality, and generally serves an important cytoprotective function. In this review we will discuss the autophagic response to reactive oxygen and nitrogen species that are generated from perturbations of cellular glucose metabolism and bioenergetic function.
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Cites
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Cited by
The basics of thiols and cysteines in redox biology and chemistry
Poole, L. B. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.11.013 · Cited by 1,031
Zhou, M., Xu, W., Wang, J., Yan, J., Shi, Y., Zhang, C., Ge, W., Wu, J., Du, P., & Chen, Y. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.08.035 · Cited by 357
Molecular chaperones and proteostasis regulation during redox imbalance
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Santos, A. L., Sinha, S., & Lindner, A. B. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/1941285 · Cited by 168
Role of Autophagy in Skin Photoaging: A Narrative Review
Zhong, X., Deng, Y., Yang, H., Du, X., Liu, P., & Du, Y. (2024) · Medicine · doi:10.1097/md.0000000000037178 · Cited by 18
Metadata
- Authors
- Dodson, M., Darley-Usmar, V., & Zhang, J.
- Venue
- Free Radical Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 2013-10
- Volume
- 63
- Pages
- 207-221
- ISSN
- 0891-5849 (ISSN-L)
- OpenAlex
- W2016985488
- Cited by
- 324
- References
- 43
- FWCI
- 26.16
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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