Developing fourth-generation biofuels secreting microbial cell factories for enhanced productivity and efficient product recovery; a review.
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Overexpression of transporters is challenging as it modifies membrane composition, creating a metabolic burden and potentially overloading cellular import/export, thereby disabling homeostasis.
“However, the overexpression of transporters is challenging as it modifies the membrane composition, creating a metabolic burden as well as potentially overloading the cellular import and export, thereby disabling the cells ability to regulate its internal environment/homeostasis [71].”
From The potential of biofuels from first to fourth generation (2023) · cites this paper as [71]
In E. coli, membrane transporters have been used successfully to excrete n-alkanes, such as n-octane.
“In E. coli, membrane transporters have been used successfully to excrete n-alkanes, such as n-octane [71,72].”
From The potential of biofuels from first to fourth generation (2023) · cites this paper as [71]
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- Authors
- Malik, S., Shahid, A., Liu, C.-G., Zafar Khan, A., Nawaz, M. Z., Zhu, H., & Mehmood, M. A.
- Affiliations
- Government College University, Faisalabad (PK)
- Shanghai Jiao Tong University (CN)
- Xiamen University (CN)
- Sichuan University of Science and Engineering (CN)
- Corresponding author
- Mehmood, Muhammad Aamer
- Venue
- Fuel
- Publisher
- Elsevier BV
- Published
- 2021-08
- Volume
- 298
- Pages
- 120858
- ISSN
- 0016-2361 (ISSN-L)
- OpenAlex
- W3155978285
- Cited by
- 35
- References
- 85
- Citations by year
- 2026: 3 · 2025: 12 · 2024: 9 · 2023: 3 · 2022: 5 · 2021: 3
- FWCI
- 0.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Fuel (publishedVersion)
- Funders
- Higher Education Commission, Pakistan (NRPU-7300)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Biochemical and biochemical processes
- Keywords
- fourth-generation biofuels, microbial cell factories, long-chain hydrocarbons, terpenoids, Escherichia coli, Saccharomyces cerevisiae, Pichia pastoris, Yarrowia lipolytica, Zymomonas mobilis, product recovery, heat shock proteins, redox homeostasis, membrane engineering, membrane transporters, efflux pumps, genetic engineering
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