Mechanistic diversity in ATP-binding cassette (ABC) transporters.

Multidrug resistance in cancer: role of ATP–dependent transporters

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ABC transporters: the power to change

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Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems

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Lipid A Modification Systems in Gram-Negative Bacteria

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The Resolution Revolution

Kühlbrandt, W. (2014) · Science · doi:10.1126/science.1251652 · Cited by 1,325 · see citing works

Structure of a bacterial multidrug ABC transporter

Dawson, R. J. P., & Locher, K. P. (2006) · Nature · doi:10.1038/nature05155 · Cited by 1,280 · see citing works

The E. coli BtuCD Structure: A Framework for ABC Transporter Architecture and Mechanism

Locher, K. P., Lee, A. T., & Rees, D. C. (2002) · Science · doi:10.1126/science.1071142 · Cited by 1,025 · see citing works

Flexibility in the ABC transporter MsbA: Alternating access with a twist

Ward, A. B., Reyes, C. L., Yu, J., Roth, C., & Chang, G. A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0709388104 · Cited by 774 · see citing works

Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System

Sarkadi, B., Homolya, L., Szakács, G., & Váradi, A. (2006) · Physiological Reviews · doi:10.1152/physrev.00037.2005 · Cited by 726 · see citing works

CFTR Function and Prospects for Therapy

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Structure and mechanism of ABC transporters

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A structural classification of substrate‐binding proteins

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Plant ATP-Binding Cassette Transporters

Rea, P. A. (2007) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105406 · Cited by 513 · see citing works

The P-glycoprotein multidrug transporter

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Crystal structure of a catalytic intermediate of the maltose transporter

Oldham, M. L., Khare, D., Quiocho, F. A., Davidson, A. L., & Chen, J. (2007) · Nature · doi:10.1038/nature06264 · Cited by 508 · see citing works

Structure of an ABC transporter in complex with its binding protein

Hollenstein, K., Frei, D. C., & Locher, K. P. (2007) · Nature · doi:10.1038/nature05626 · Cited by 506 · see citing works

Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans

Jin, M. S., Oldham, M. L., Zhang, Q., & Chen, J. (2012) · Nature · doi:10.1038/nature11448 · Cited by 467 · see citing works

Multifunctionality of plant ABC transporters – more than just detoxifiers

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Structure and mechanism of ATP-binding cassette transporters

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Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP‐PNP

Dawson, R. J. P., & Locher, K. P. (2007) · FEBS Letters · doi:10.1016/j.febslet.2007.01.073 · Cited by 408 · see citing works

Structural diversity of ABC transporters

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Refined structures of mouse P‐glycoprotein

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In Vitro Inhibition of the Bile Salt Export Pump Correlates with Risk of Cholestatic Drug-Induced Liver Injury in Humans

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Asymmetry in the Structure of the ABC Transporter-Binding Protein Complex BtuCD-BtuF

Hvorup, R. N., Goetz, B. A., Niederer, M., Hollenstein, K., Perozo, E., & Locher, K. P. (2007) · Science · doi:10.1126/science.1145950 · Cited by 280 · see citing works

ABC transporter-mediated uptake of iron, siderophores, heme and vitamin B12

Köster, W. L. (2001) · Research in Microbiology · doi:10.1016/s0923-2508(01)01200-1 · Cited by 277 · see citing works

Structural insights into ABC transporter mechanism

Oldham, M. L., Davidson, A. L., & Chen, J. (2008) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2008.09.007 · Cited by 272 · see citing works

Type 1 protein secretion in bacteria, the ABC-transporter dependent pathway (Review)

Holland, I. B., Schmitt, L., & Young, J. P. (2005) · Molecular Membrane Biology · doi:10.1080/09687860500042013 · Cited by 269 · see citing works

Recent insights into iron import by bacteria

Braun, V., & Hantke, K. (2011) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2011.01.005 · Cited by 264 · see citing works

Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli

Ruiz, N., Gronenberg, L. S., Kahne, D. E., & Silhavy, T. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801196105 · Cited by 262 · see citing works

Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

Ward, A. B., Szewczyk, P., Grimard, V., Lee, C., Martinez, L., Doshi, R., Caya, A., Villaluz, M., Pardon, E., Cregger, C., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1309275110 · Cited by 257 · see citing works

Prediction of drug–ABC-transporter interaction — Recent advances and future challenges

Montanari, F., & Ecker, G. F. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.03.001 · Cited by 256 · see citing works

Human P-Glycoprotein Exhibits Reduced Affinity for Substrates during a Catalytic Transition State

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Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation

Hohl, M., Briand, C., Grütter, M. G., & Seeger, M. A. (2012) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2267 · Cited by 245 · see citing works

A Multifactorial Approach to Hepatobiliary Transporter Assessment Enables Improved Therapeutic Compound Development

Morgan, R. E., van Staden, C. J., Chen, Y., Kalyanaraman, N., Kalanzi, J., Dunn, R. T., Afshari, C. A., & Hamadeh, H. K. (2013) · Toxicological Sciences · doi:10.1093/toxsci/kft176 · Cited by 243 · see citing works

Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states

Shintre, C. A., Pike, A. C. W., Li, Q., Kim, J.-I., Barr, A., Goubin, S., Shrestha, L., Yang, J., Berridge, G., Ross, J. E., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1217042110 · Cited by 240 · see citing works

The controversial role of ABC transporters in clinical oncology

Tamaki, A., Ieranò, C., Szakács, G., Robey, R. W., & Bates, S. E. (2011) · Essays in Biochemistry · doi:10.1042/bse0500209 · Cited by 235 · see citing works

Structure, biosynthesis, and function of bacterial capsular polysaccharides synthesized by ABC transporter-dependent pathways

Willis, L. M., & Whitfield, C. (2013) · Carbohydrate Research · doi:10.1016/j.carres.2013.05.007 · Cited by 231 · see citing works

The High-Affinity E. coli Methionine ABC Transporter: Structure and Allosteric Regulation

Kadaba, N. S., Kaiser, J. T., Johnson, E., Lee, A. T., & Rees, D. C. (2008) · Science · doi:10.1126/science.1157987 · Cited by 218 · see citing works

Crystal Structures of Nucleotide-Free and Glutathione-Bound Mitochondrial ABC Transporter Atm1

Srinivasan, V., Pierik, A. J., & Lill, R. (2014) · Science · doi:10.1126/science.1246729 · Cited by 212 · see citing works

Structure and mechanism of an active lipid-linked oligosaccharide flippase

Pérez, C., Gerber, S., Boilevin, J., Bucher, M., Darbre, T., Aebi, M., Reymond, J., & Locher, K. P. (2015) · Nature · doi:10.1038/nature14953 · Cited by 209 · see citing works

ABC Transporters Involved in Export of Cell Surface Glycoconjugates

Cuthbertson, L., Kos, V. N., & Whitfield, C. (2010) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00009-10 · Cited by 206 · see citing works

Trapping the transition state of an ATP-binding cassette transporter: Evidence for a concerted mechanism of maltose transport

Chen, J., Sharma, S., Quiocho, F. A., & Davidson, A. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.4.1525 · Cited by 197 · see citing works

Structure of an antibacterial peptide ATP-binding cassette transporter in a novel outward occluded state

Choudhury, H. G., Tong, Z., Mathavan, I., Li, Y., Iwata, S., Zirah, S., Rebuffat, S., van Veen, H. W., & Beis, K. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1320506111 · Cited by 196 · see citing works

Structural Basis of Trans-Inhibition in a Molybdate/Tungstate ABC Transporter

Gerber, S., Comellas-Bigler, M., Goetz, B. A., & Locher, K. P. (2008) · Science · doi:10.1126/science.1156213 · Cited by 188 · see citing works

Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog

Kodan, A., Yamaguchi, T., Nakatsu, T., Sakiyama, K., Hipolito, C. J., Fujioka, A., Hirokane, R., Ikeguchi, K., Watanabe, B., Hiratake, J., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1321562111 · Cited by 177 · see citing works

Structure of AMP-PNP-bound vitamin B12 transporter BtuCD–F

Korkhov, V. M., Mireku, S. A., & Locher, K. P. (2012) · Nature · doi:10.1038/nature11442 · Cited by 174 · see citing works

Molecular basis of multidrug transport by ABC transporters

Seeger, M. A., & van Veen, H. W. (2008) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2008.12.004 · Cited by 171 · see citing works

Structural Basis for Heavy Metal Detoxification by an Atm1-Type ABC Exporter

Lee, J. Y., Yang, J. G., Zhitnitsky, D., Lewinson, O., & Rees, D. C. (2014) · Science · doi:10.1126/science.1246489 · Cited by 170 · see citing works

ABCC8 and ABCC9: ABC transporters that regulate K+ channels

Bryan, J., Muñoz, A., Zhang, X., Düfer, M., Drews, G., Krippeit‐Drews, P., & Aguilar‐Bryan, L. (2006) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-006-0116-z · Cited by 163 · see citing works

Mechanistic picture for conformational transition of a membrane transporter at atomic resolution

Moradi, M., & Tajkhorshid, E. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1313202110 · Cited by 159 · see citing works

The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter

Procko, E., O’Mara, M. L., Bennett, W. F., Tieleman, D. P., & Gaudet, R. (2009) · The FASEB Journal · doi:10.1096/fj.08-121855 · Cited by 158 · see citing works

A structural analysis of asymmetry required for catalytic activity of an ABC‐ATPase domain dimer

Zaitseva, J., Oswald, C., Jumpertz, T., Jenewein, S., Wiedenmann, A., Holland, I. B., & Schmitt, L. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601208 · Cited by 156 · see citing works

SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator

Aittoniemi, J., Fotinou, C., Craig, T. J., de Wet, H., Proks, P., & Ashcroft, F. (2009) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0142 · Cited by 155 · see citing works

Conformational Motion of the ABC Transporter MsbA Induced by ATP Hydrolysis

Borbat, P. P., Surendhran, K., Bortolus, M., et al. (2007) · PLoS Biology · doi:10.1371/journal.pbio.0050271 · Cited by 154 · see citing works

Uptake or extrusion: crystal structures of full ABC transporters suggest a common mechanism

Dawson, R. J. P., Hollenstein, K., & Locher, K. P. (2007) · Molecular Microbiology · doi:10.1111/j.1365-2958.2007.05792.x · Cited by 149 · see citing works

The substrate-binding protein in bacterial ABC transporters: dissecting roles in the evolution of substrate specificity

Maqbool, A., Horler, R. S. P., Müller, A., Wilkinson, A. J., Wilson, K. S., & Thomas, G. H. (2015) · Biochemical Society Transactions · doi:10.1042/bst20150135 · Cited by 141 · see citing works

Role of the bile salt export pump, BSEP, in acquired forms of cholestasis

Stieger, B. (2009) · Drug Metabolism Reviews · doi:10.3109/03602530903492004 · Cited by 134 · see citing works

The ATP/Substrate Stoichiometry of the ATP-binding Cassette (ABC) Transporter OpuA

Patzlaff, J. S., van der Heide, T., & Poolman, B. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304796200 · Cited by 134 · see citing works

Canalicular ABC transporters and liver disease

Nicolaou, M., Andress, E. J., Zolnerciks, J. K., Dixon, P. H., Williamson, C., & Linton, K. J. (2011) · The Journal of Pathology · doi:10.1002/path.3019 · Cited by 128 · see citing works

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

Mishra, S., Verhalen, B., Stein, R. A., Wen, P., Tajkhorshid, E., & Mchaourab, H. S. (2014) · eLife · doi:10.7554/elife.02740 · Cited by 124 · see citing works

Perspectives on the structure–function of ABC transporters: The Switch and Constant Contact Models

George, A. M., & Jones, P. M. (2012) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2012.06.003 · Cited by 124 · see citing works

A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter

Oldham, M. L., Hite, R. K., Steffen, A. M., Damko, E., Li, Z., Walz, T., & Chen, J. (2016) · Nature · doi:10.1038/nature16506 · Cited by 124 · see citing works

Towards understanding promiscuity in multidrug efflux pumps

Wong, K., Ma, J., Rothnie, A. J., Biggin, P. C., & Kerr, I. D. (2013) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2013.11.002 · Cited by 121 · see citing works

Crystal structures of a polypeptide processing and secretion transporter

Lin, D. Y.-W., Huang, S., & Chen, J. (2015) · Nature · doi:10.1038/nature14623 · Cited by 118 · see citing works

Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter

Hohl, M., Hürlimann, L. M., Böhm, S., Schöppe, J., Grütter, M. G., Bordignon, E., & Seeger, M. A. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1400485111 · Cited by 118 · see citing works

Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter

Kim, J., Wu, S., Tomasiak, T. M., et al. (2014) · Nature · doi:10.1038/nature13872 · Cited by 118 · see citing works

Multiple Transport-Active Binding Sites Are Available for a Single Substrate on Human P-Glycoprotein (ABCB1)

Chufán, E. E., Kapoor, K., Sim, H. M., Singh, S., Talele, T. T., Durell, S. R., & Ambudkar, S. V. (2013) · PLoS ONE · doi:10.1371/journal.pone.0082463 · Cited by 117 · see citing works

Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter

Grossmann, N., Vakkasoglu, A. S., Hulpke, S., et al. (2014) · Nature Communications · doi:10.1038/ncomms6419 · Cited by 111 · see citing works

Crystal structure of a folate energy-coupling factor transporter from Lactobacillus brevis

Xu, K., Zhang, M., Zhao, Q., Yu, F., Guo, H., Wang, C., He, F., Ding, J., & Zhang, P. (2013) · Nature · doi:10.1038/nature12046 · Cited by 100 · see citing works

Evolution of ABC transporters by gene duplication and their role in human disease

Moitra, K., & Dean, M. C. (2011) · Biological Chemistry · doi:10.1515/bc.2011.006 · Cited by 96 · see citing works

Carbon catabolite repression of the maltose transporter revealed by X-ray crystallography

Chen, S., Oldham, M. L., Davidson, A. L., & Chen, J. (2013) · Nature · doi:10.1038/nature12232 · Cited by 95 · see citing works

The transporter associated with antigen processing: a key player in adaptive immunity

Eggensperger, S., & Tampé, R. (2015) · Biological Chemistry · doi:10.1515/hsz-2014-0320 · Cited by 93 · see citing works

Mutational analysis of ABC proteins

Loo, T. W., & Clarke, D. M. (2008) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2008.02.025 · Cited by 86 · see citing works

Membrane Porters of ATP-Binding Cassette Transport Systems Are Polyphyletic

Wang, B., Dukarevich, M., Sun, E. I., Yen, M. R., & Saier, M. H. (2009) · The Journal of Membrane Biology · doi:10.1007/s00232-009-9200-6 · Cited by 85 · see citing works

Multiple Drug Transport Pathways through Human P-Glycoprotein

McCormick, J. W., Vogel, P. D., & Wise, J. G. (2015) · Biochemistry · doi:10.1021/acs.biochem.5b00018 · Cited by 79 · see citing works

Structure of AMP-PNP–bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD–F

Korkhov, V. M., Mireku, S. A., Veprintsev, D. B., et al. (2014) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2918 · Cited by 77 · see citing works

Molecular Mechanisms for Biliary Phospholipid and Drug Efflux Mediated by ABCB4 and Bile Salts

Morita, S., & Terada, T. (2014) · BioMed Research International · doi:10.1155/2014/954781 · Cited by 77 · see citing works

ABC solute importers in bacteria

Cui, J., & Davidson, A. L. (2011) · Essays in Biochemistry · doi:10.1042/bse0500085 · Cited by 74 · see citing works

Advances in the Molecular Detection of ABC Transporters Involved in Multidrug Resistance in Cancer

Gillet, J., & Gottesman, M. M. (2011) · Current Pharmaceutical Biotechnology · doi:10.2174/138920111795163931 · Cited by 72 · see citing works

Transmembrane Gate Movements in the Type II ATP-binding Cassette (ABC) Importer BtuCD-F during Nucleotide Cycle

Joseph, B., Jeschke, G., Goetz, B. A., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.269472 · Cited by 68 · see citing works

Asymmetric ATP Hydrolysis Cycle of the Heterodimeric Multidrug ABC Transport Complex TmrAB from Thermus thermophilus

Zutz, A., Hoffmann, J., Hellmich, U. A., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.201178 · Cited by 67 · see citing works

Multidrug efflux pumps: The structures of prokaryotic ATP‐binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P‐glycoproteins and homologues

Kerr, I. D., Jones, P. M., & George, A. M. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.07486.x · Cited by 64 · see citing works

Human P-glycoprotein is active when the two halves are clamped together in the closed conformation

Loo, T. W., Bartlett, M. C., & Clarke, D. M. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.04.057 · Cited by 57 · see citing works

Conformation of peptides bound to the transporter associated with antigen processing (TAP)

Herget, M., Baldauf, C., Scholz, C. W., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1012355108 · Cited by 50 · see citing works

Asymmetry in the Homodimeric ABC Transporter MsbA Recognized by a DARPin

Mittal, A., Böhm, S., Grütter, M. G., Bordignon, E., & Seeger, M. A. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.359794 · Cited by 49 · see citing works

ATP hydrolysis-driven gating in cystic fibrosis transmembrane conductance regulator

Muallem, D. R., & Vergani, P. (2008) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2008.0191 · Cited by 46 · see citing works

Structure of a Bacterial ABC Transporter Involved in the Import of an Acidic Polysaccharide Alginate

Maruyama, Y., Itoh, T., Kaneko, A., Nishitani, Y., Mikami, B., Hashimoto, W., & Murata, K. (2015) · Structure · doi:10.1016/j.str.2015.06.021 · Cited by 45 · see citing works

A reciprocating twin-channel model for ABC transporters

Jones, P. M., & George, A. M. (2014) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583514000031 · Cited by 40 · see citing works

The central cavity of ABCB 1 undergoes alternating access during ATP hydrolysis

van Wonderen, J. H., McMahon, R. M., O’Mara, M. L., et al. (2014) · FEBS Journal · doi:10.1111/febs.12773 · Cited by 40 · see citing works

Watching conformational dynamics of ABC transporters with single-molecule tools

Husada, F., Gouridis, G., Vietrov, R., et al. (2015) · Biochemical Society Transactions · doi:10.1042/bst20150140 · Cited by 39 · see citing works

Structure and mechanism of energy-coupling factor transporters

Zhang, P. (2013) · Trends in Microbiology · doi:10.1016/j.tim.2013.09.009 · Cited by 37 · see citing works

Lipid flopping in the liver

Linton, K. J. (2015) · Biochemical Society Transactions · doi:10.1042/bst20150132 · Cited by 36 · see citing works

Evolutionary relationships of ATP-Binding Cassette (ABC) uptake porters

Zheng, W. H., Västermark, Å., Shlykov, M. A., et al. (2013) · BMC Microbiology · doi:10.1186/1471-2180-13-98 · Cited by 34 · see citing works

Distinct gate conformations of the ABC transporter BtuCD revealed by electron spin resonance spectroscopy and chemical cross‐linking

Goetz, B. A., Perozo, E., & Locher, K. P. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.12.020 · Cited by 34 · see citing works

ABC transporters involved in drug resistance in human parasites.

Leprohon, P., Légaré, D., & Ouellette, M. (2011) · Essays in Biochemistry · doi:10.1042/bse0500121 · Cited by 30 · see citing works

The Allosteric Regulatory Mechanism of the Escherichia coli MetNI Methionine ATP Binding Cassette (ABC) Transporter

Yang, J. G., & Rees, D. C. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.603365 · Cited by 29 · see citing works

Overview of Experimental Models of the Blood‐Brain Barrier in CNS Drug Discovery

Palmer, A. M., & Alavijeh, M. S. (2013) · Current Protocols in Pharmacology · doi:10.1002/0471141755.ph0715s62 · Cited by 27 · see citing works

Conformational Changes of the Antibacterial Peptide ATP Binding Cassette Transporter McjD Revealed by Molecular Dynamics Simulations

Gu, R., Corradi, V., Singh, G., Choudhury, H. G., Beis, K., & Tieleman, D. P. (2015) · Biochemistry · doi:10.1021/acs.biochem.5b00753 · Cited by 25 · see citing works

The TAP translocation machinery in adaptive immunity and viral escape mechanisms

Abele, R., & Tampé, R. (2011) · Essays in Biochemistry · doi:10.1042/bse0500249 · Cited by 20 · see citing works

Investigating the dynamic nature of the ABC transporters: ABCB1 and MsbA as examples for the potential synergies of MD theory and EPR applications

Stockner, T., Mullen, A., & MacMillan, F. (2015) · Biochemical Society Transactions · doi:10.1042/bst20150138 · Cited by 12 · see citing works

Metabolic regulatory crosstalk between tumor microenvironment and tumor-associated macrophages

Chen, D., Zhang, X., Li, Z., & Zhu, B. (2021) · Theranostics · doi:10.7150/thno.51777 · Cited by 390 · see citing works

An updated structural classification of substrate-binding proteins.

Scheepers, G. H., Lycklama a Nijeholt, J. A., & Poolman, B. (2016) · FEBS Letters · doi:10.1002/1873-3468.12445 · Cited by 260 · see citing works

Structure of a Pancreatic ATP-Sensitive Potassium Channel

Li, N., Wu, J.-X., Ding, D., Cheng, J., Gao, N., & Chen, L. (2017) · Cell · doi:10.1016/j.cell.2016.12.028 · Cited by 252 · see citing works

Not only P-glycoprotein: Amplification of the ABCB1- containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins

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Structural and molecular mechanisms for membrane protein biogenesis by the Oxa1 superfamily.

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Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1

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Bile resistance mechanisms in probiotics: From structural adaptation to metabolic regulation

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Optimizing Stability in Dynamic Small-Molecule Binding Proteins

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Trafficking of Canalicular ABC Transporters in Hepatocytes

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The ATP-Binding Cassette Transporters and Their Implication in Drug Disposition: A Special Look at the Heart

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ABC transporters. Lessons from a bacterial oligopeptide uptake system

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Multi Drug Resistance P Glycoprotein and other Transporters

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