Spatial chromatin organization and gene regulation at the nuclear lamina

Topological domains in mammalian genomes identified by analysis of chromatin interactions

Dixon, J. R., Selvaraj, S., Yue, F., Kim, A., Li, Y., Shen, Y., Hu, M., Liu, J. S., & Ren, B. (2012) · Nature · doi:10.1038/nature11082 · Cited by 6,829 · see citing works

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

Bannister, A. J., Zegerman, P., Partridge, J. F., Miska, E. A., Thomas, J. O., Allshire, R. C., & Kouzarides, T. (2001) · Nature · doi:10.1038/35065138 · Cited by 2,903 · see citing works

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

Lachner, M., O'Carroll, D., Rea, S., Mechtler, K., & Jenuwein, T. (2001) · Nature · doi:10.1038/35065132 · Cited by 2,868 · see citing works

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

Guelen, L., Pagie, L., Brasset, É., Meuleman, W. R. A., Faza, M. B., Talhout, W., Eussen, B. H. J., de Klein, A., Wessels, L. F. A., de Laat, W. L., et al. (2008) · Nature · doi:10.1038/nature06947 · Cited by 1,959 · see citing works

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

Peric-Hupkes, D., Meuleman, W., Pagie, L., Bruggeman, S. W. M., Solovei, I., Brugman, W., Gräf, S., Flicek, P., Kerkhoven, R. M., van Lohuizen, M., et al. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.03.016 · Cited by 1,050 · see citing works

Systematic Protein Location Mapping Reveals Five Principal Chromatin Types in Drosophila Cells

Filion, G. J. P., van Bemmel, J. G., Braunschweig, U., Talhout, W., Kind, J., Ward, L. D., Brugman, W., de Castro, I. J., Kerkhoven, R. M., Bussemaker, H. J., et al. (2010) · Cell · doi:10.1016/j.cell.2010.09.009 · Cited by 963 · see citing works

Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome

Soufi, A., Donahue, G., & Zaret, K. S. (2012) · Cell · doi:10.1016/j.cell.2012.09.045 · Cited by 887 · see citing works

ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells

Ou, H. D., Phan, S., Deerinck, T. J., Thor, A., Ellisman, M. H., & O’Shea, C. C. (2017) · Science · doi:10.1126/science.aag0025 · Cited by 872 · see citing works

Comprehensive analysis of the chromatin landscape in Drosophila melanogaster

Kharchenko, P. V., Alekseyenko, A. A., Schwartz, Y. B., Minoda, A., Riddle, N. C., Ernst, J., Sabo, P. J., Larschan, E., Gorchakov, A. A., Gu, T., et al. (2010) · Nature · doi:10.1038/nature09725 · Cited by 853 · see citing works

LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation

Solovei, I., Wang, A. S., Thanisch, K., Schmidt, C. S., Krebs, S., Zwerger, M., Cohen, T. V., Devys, D., Foisner, R., Peichl, L., et al. (2013) · Cell · doi:10.1016/j.cell.2013.01.009 · Cited by 809 · see citing works

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

Solovei, I. V., Kreysing, M., Lanctôt, C., Kösem, S., Peichl, L., Cremer, T. J., Guck, J. R., & Joffe, B. I. (2009) · Cell · doi:10.1016/j.cell.2009.01.052 · Cited by 785 · see citing works

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

Reddy, K. L., Zullo, J., Bertolino, E., & Singh, H. (2008) · Nature · doi:10.1038/nature06727 · Cited by 785 · see citing works

Single-Cell Dynamics of Genome-Nuclear Lamina Interactions

Kind, J., Pagie, L., Ortabozkoyun, H., Boyle, S., de Vries, S., Janssen, H., Amendola, M., Nolen, L. D., Bickmore, W. A., & van Steensel, B. (2013) · Cell · doi:10.1016/j.cell.2013.02.028 · Cited by 716 · see citing works

Characterization of the Drosophila melanogaster genome at the nuclear lamina

Pickersgill, H., Kalverda, B., de Wit, E., Talhout, W., Fornerod, M., & van Steensel, B. (2006) · Nature Genetics · doi:10.1038/ng1852 · Cited by 656 · see citing works

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

Wen, B., Wu, H., Shinkai, Y., Irizarry, R. A., & Feinberg, A. P. (2009) · Nature Genetics · doi:10.1038/ng.297 · Cited by 615 · see citing works

Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery

Towbin, B. D., González-Aguilera, C., Sack, R., Gaidatzis, D., Kalck, V., Meister, P., Askjaer, P., & Gasser, S. M. (2012) · Cell · doi:10.1016/j.cell.2012.06.051 · Cited by 597 · see citing works

Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

Finlan, L. E., Sproul, D., Thomson, I., Boyle, S., Kerr, E. A., Perry, P., Ylstra, B., Chubb, J. R., & Bickmore, W. A. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000039 · Cited by 584 · see citing works

Genome-wide chromatin state transitions associated with developmental and environmental cues

Zhu, J., Adli, M., Zou, J., Verstappen, G., Coyne, M. J., Zhang, X.-L., Durham, T. J., Miri, M., Deshpande, V., Jager, P. D., et al. (2013) · Cell · doi:10.1016/j.cell.2012.12.033 · Cited by 553 · see citing works

Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells

Kind, J., Pagie, L., de Vries, S., Nahidiazar, L., Dey, S. S., Bienko, M., Zhan, Y., Lajoie, B. R., de Graaf, C. A., Amendola, M., et al. (2015) · Cell · doi:10.1016/j.cell.2015.08.040 · Cited by 467 · see citing works

Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

Meuleman, W., Peric-Hupkes, D., Kind, J., Beaudry, J.-B., Pagie, L., Kellis, M., Reinders, M., Wessels, L., & van Steensel, B. (2013) · Genome Research · doi:10.1101/gr.141028.112 · Cited by 462 · see citing works

DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina

Zullo, J., Demarco, I. A., Piqué-Regi, R., Gaffney, D. J., Epstein, C. B., Spooner, C. J., Luperchio, T. R., Bernstein, B., Pritchard, J. K., Reddy, K. L., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.035 · Cited by 448 · see citing works

The molecular architecture of lamins in somatic cells

Turgay, Y., Eibauer, M., Goldman, A. E., Shimi, T., Khayat, M., Ben‐Harush, K., Dubrovsky-Gaupp, A., Sapra, K. T., Goldman, R. D., & Medalia, O. (2017) · Nature · doi:10.1038/nature21382 · Cited by 428 · see citing works

A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence

Kumaran, R. I., & Spector, D. L. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200706060 · Cited by 388 · see citing works

Initial Genomics of the Human Nucleolus

Németh, A., Conesa, A., Santoyo‐López, J., Medina, I., Montaner, D. A., Péterfia, B. F., Solovei, I. V., Cremer, T. J., Dopazo, J., & Längst, G. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1000889 · Cited by 383 · see citing works

On the occurrence of a fibrous lamina on the inner aspect of the nuclear envelope in certain cells of vertebrates

Fawcett, D. W. (1966) · American Journal of Anatomy · doi:10.1002/aja.1001190108 · Cited by 374 · see citing works

Nuclear Aggregation of Olfactory Receptor Genes Governs Their Monogenic Expression

Clowney, E. J., LeGros, M., Mosley, C., Clowney, F., Markenscoff-Papadimitriou, E., Myllys, M., Barnea, G., Larabell, C. A., & Lomvardas, S. (2012) · Cell · doi:10.1016/j.cell.2012.09.043 · Cited by 362 · see citing works

Domain-specific Interactions of Human HP1-type Chromodomain Proteins and Inner Nuclear Membrane Protein LBR

Ye, Q., Callebaut, I., Pezhman, A., Courvalin, J., & Worman, H. J. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.23.14983 · Cited by 345 · see citing works

Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins

Harr, J. C., Luperchio, T. R., Wong, X., Cohen, E., Wheelan, S. J., & Reddy, K. L. (2015) · The Journal of Cell Biology · doi:10.1083/jcb.201405110 · Cited by 338 · see citing works

High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli

van Koningsbruggen, S., Gierliński, M., Schofield, P., Martin, D. M. A., Barton, G. J., Ariyürek, Y., den Dunnen, J. T., & Lamond, A. I. (2010) · Molecular Biology of the Cell · doi:10.1091/mbc.e10-06-0508 · Cited by 327 · see citing works

Chromatin Position Effects Assayed by Thousands of Reporters Integrated in Parallel

Akhtar, W., de Jong, J., Pindyurin, A. V., Pagie, L., Meuleman, W. R. A., de Ridder, J., Berns, A. J. M., Wessels, L. F. A., van Lohuizen, M., & van Steensel, B. (2013) · Cell · doi:10.1016/j.cell.2013.07.018 · Cited by 318 · see citing works

Nuclear Lamins: Thin Filaments with Major Functions

de Leeuw, R., Gruenbaum, Y., & Medalia, O. (2017) · Trends in Cell Biology · doi:10.1016/j.tcb.2017.08.004 · Cited by 300 · see citing works

Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells

Therizols, P., Illingworth, R. S., Courilleau, C., Boyle, S., Wood, A. J., & Bickmore, W. A. (2014) · Science · doi:10.1126/science.1259587 · Cited by 284 · see citing works

Global Chromatin Architecture Reflects Pluripotency and Lineage Commitment in the Early Mouse Embryo

Ahmed, K., Dehghani, H., Rugg‐Gunn, P. J., Fussner, E., Rossant, J., & Bazett‐Jones, D. P. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010531 · Cited by 264 · see citing works

Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy

Shimi, T., Kittisopikul, M., Tran, J. R., Goldman, A. E., Adam, S. A., Zheng, Y., Jaqaman, K., & Goldman, R. D. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-07-0461 · Cited by 247 · see citing works

Lamins Organize the Global Three-Dimensional Genome from the Nuclear Periphery

Zheng, X., Hu, J., Yue, S., Kristiani, L., Kim, M., Sauria, M. E. G., Taylor, J., Kim, Y., & Zheng, Y. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.05.017 · Cited by 238 · see citing works

Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos

Gonzalez‐Sandoval, A., Towbin, B. D., Kalck, V., Cabianca, D. S., Gaidatzis, D., Hauer, M., Geng, L., Wang, L., Yang, T., Wang, X., et al. (2015) · Cell · doi:10.1016/j.cell.2015.10.066 · Cited by 227 · see citing works

The nuclear-envelope protein and transcriptional repressor LAP2β interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation

Somech, R., Shaklai, S., Geller, O., Amariglio, N., Simon, A. J., Rechavi, G., & Gal-Yam, E. N. (2005) · Journal of Cell Science · doi:10.1242/jcs.02521 · Cited by 223 · see citing works

Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction

Poleshko, A. S., Shah, P. P., Gupta, M., Babu, A., Morley, M. P., Manderfield, L. J., Ifkovits, J. L., Calderon, D., Aghajanian, H. K., Sierra-Pagán, J. E., et al. (2017) · Cell · doi:10.1016/j.cell.2017.09.018 · Cited by 219 · see citing works

Caenorhabditis elegans chromosome arms are anchored to the nuclear membrane via discontinuous association with LEM-2

Ikegami, K., Egelhofer, T. A., Strome, S., & Lieb, J. D. (2010) · Genome biology · doi:10.1186/gb-2010-11-12-r120 · Cited by 193 · see citing works

Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis

Robson, M. I., Heras, J. I. D. L., Czapiewski, R., Thanh, P. L., Booth, D. G., Kelly, D. A., Webb, S., Kerr, A. R. W., & Schirmer, E. C. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.04.035 · Cited by 190 · see citing works

The Carboxyl-Terminal Region Common to Lamins A and C Contains a DNA Binding Domain

Stierlé, V., Couprie, J., Östlund, C., Krimm, I., Zinn‐Justin, S., Hossenlopp, P., Worman, H. J., Courvalin, J., & Duband‐Goulet, I. (2003) · Biochemistry · doi:10.1021/bi020704g · Cited by 188 · see citing works

Histones H3/H4 form a tight complex with the inner nuclear membrane protein LBR and heterochromatin protein 1

Polioudaki, H., Kourmouli, N., Drosou, V., Bakou, A., Theodoropoulos, P. A., Singh, P. B., Giannakouŕos, T., & Georgatos, S. D. (2001) · EMBO Reports · doi:10.1093/embo-reports/kve199 · Cited by 179 · see citing works

G9a selectively represses a class of late-replicating genes at the nuclear periphery

Yokochi, T., Poduch, K., Ryba, T., Lu, J., Hiratani, I., Tachibana, M., Shinkai, Y., & Gilbert, D. M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906142106 · Cited by 162 · see citing works

Developmentally Regulated Subnuclear Genome Reorganization Restricts Neural Progenitor Competence in Drosophila

Kohwi, M., Lupton, J. R., Lai, S.-L., Miller, M. R., & Doe, C. Q. (2013) · Cell · doi:10.1016/j.cell.2012.11.049 · Cited by 159 · see citing works

Lamin B1 controls oxidative stress responses via Oct-1

Malhas, A. N., Lee, C. F., & Vaux, D. J. (2009) · The Journal of Cell Biology · doi:10.1083/jcb.200804155 · Cited by 158 · see citing works

The alpha‐helical rod domain of human lamins A and C contains a chromatin binding site.

Glass, C. A., Glass, J. R., Taniura, H., Hasel, K. W., Blevitt, J. M., & Gerace, L. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06126.x · Cited by 156 · see citing works

A-type Lamins Form Distinct Filamentous Networks with Differential Nuclear Pore Complex Associations

Xie, W., Chojnowski, A., Boudier, T., Lim, J., Ahmed, S., Ser, Z., Stewart, C. L., & Burke, B. E. (2016) · Current Biology · doi:10.1016/j.cub.2016.07.049 · Cited by 147 · see citing works

The B-type lamin is required for somatic repression of testis-specific gene clusters

Shevelyov, Y. Y., Lavrov, S. A., Mikhaylova, L. M., Nurminsky, I. D., Kulathinal, R. J., Egorova, K. S., Rozovsky, Y. M., & Nurminsky, D. I. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811933106 · Cited by 133 · see citing works

Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells

Ugarte, F., Sousae, R., Cinquin, B. P., Martin, E. W., Krietsch, J., Sanchez, G., Inman, M., Tsang, H., Warr, M. R., Passegue, E. A., et al. (2015) · Stem Cell Reports · doi:10.1016/j.stemcr.2015.09.009 · Cited by 130 · see citing works

An EDMD Mutation in C. elegans Lamin Blocks Muscle-Specific Gene Relocation and Compromises Muscle Integrity

Mattout, A., Pike, B. L., Towbin, B. D., Bank, E. M., Gonzalez‐Sandoval, A., Stadler, M. B., Meister, P., Gruenbaum, Y., & Gasser, S. M. (2011) · Current Biology · doi:10.1016/j.cub.2011.08.030 · Cited by 129 · see citing works

Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery

Zuleger, N., Boyle, S., Kelly, D. A., Heras, J. I. D. L., Lazou, V., Korfali, N., Batrakou, D. G., Randles, K. N., Morris, G. E., Harrison, D. J., et al. (2013) · Genome biology · doi:10.1186/gb-2013-14-2-r14 · Cited by 123 · see citing works

β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications

Bian, Q., Khanna, N., Alvikas, J., & Belmont, A. S. (2013) · The Journal of Cell Biology · doi:10.1083/jcb.201305027 · Cited by 122 · see citing works

The Insulator Protein SU(HW) Fine-Tunes Nuclear Lamina Interactions of the Drosophila Genome

van Bemmel, J. G., Pagie, L., Braunschweig, U., Brugman, W., Meuleman, W. R. A., Kerkhoven, R. M., & van Steensel, B. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015013 · Cited by 120 · see citing works

The Human Protein PRR14 Tethers Heterochromatin to the Nuclear Lamina during Interphase and Mitotic Exit

Poleshko, A. S., Mansfield, K. M., Burlingame, C. C., Andrake, M., Shah, N. R., & Katz, R. A. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.09.024 · Cited by 118 · see citing works

Lamin B Receptor Recognizes Specific Modifications of Histone H4 in Heterochromatin Formation

Hirano, Y., Hizume, K., Kimura, H., Takeyasu, K., Haraguchi, T., & Hiraoka, Y. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.397950 · Cited by 111 · see citing works

Simultaneous quantification of protein–DNA contacts and transcriptomes in single cells

Rooijers, K., Markodimitraki, C. M., Rang, F. J., de Vries, S. S., Chialastri, A., de Luca, K. L., Mooijman, D., Dey, S. S., & Kind, J. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0150-y · Cited by 110 · see citing works

Emerin and histone deacetylase 3 (HDAC3) cooperatively regulate expression and nuclear positions of MyoD, Myf5, and Pax7 genes during myogenesis

Demmerle, J., Koch, A. J., & Holaska, J. M. (2013) · Chromosome Research · doi:10.1007/s10577-013-9381-9 · Cited by 89 · see citing works

Massive reshaping of genome-nuclear lamina interactions during oncogene-induced senescence.

Lenain, C., de Graaf, C. A., Pagie, L., Visser, N. L., de Haas, M., de Vries, S. S., Peric-Hupkes, D., van Steensel, B., & Peeper, D. S. (2017) · Genome Research · doi:10.1101/gr.225763.117 · Cited by 89 · see citing works

Loss of lamin B receptor is necessary to induce cellular senescence

Lukášová, E., Kovařı́k, A., Bačı́ková, A., Falk, M., & Kozubek, S. (2016) · Biochemical Journal · doi:10.1042/bcj20160459 · Cited by 68 · see citing works

LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription

Mirza, A., McKellar, S. A., Urman, N. M., Brown, A. S., Hollmig, T., Aasi, S. Z., & Oro, A. E. (2018) · Cell · doi:10.1016/j.cell.2018.10.054 · Cited by 68 · see citing works

Viewing Nuclear Architecture through the Eyes of Nocturnal Mammals

Feodorova, Y. N., Falk, M. J., Mirny, L. A., & Solovei, I. V. (2020) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.12.008 · Cited by 49 · see citing works

Influences of lamin A levels on induction of pluripotent stem cells

Zuo, B., Yang, J., Wang, F., Wang, L., Yin, Y., Dan, J., Liu, N., & Liu, L. (2012) · Biology Open · doi:10.1242/bio.20121586 · Cited by 48 · see citing works

Role of Histone Deacetylases in Gene Regulation at Nuclear Lamina

Milon, B. C., Cheng, H., Tselebrovsky, M. V., Lavrov, S. A., Nenasheva, V. V., Mikhaleva, E. A., Shevelyov, Y. Y., & Nurminsky, D. I. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049692 · Cited by 44 · see citing works

The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a

Pindyurin, A. V., Ilyin, A. A., Ivankin, A. V., Tselebrovsky, M. V., Nenasheva, V. V., Mikhaleva, E. A., Pagie, L., van Steensel, B., & Shevelyov, Y. Y. (2018) · Epigenetics & Chromatin · doi:10.1186/s13072-018-0235-8 · Cited by 36 · see citing works

Oct-1 recruitment to the nuclear envelope in adult-onset autosomal dominant leukodystrophy

Columbaro, M., Mattioli, E., Maraldi, N. M., Ortolani, M., Gasparini, L., D’Apice, M. R., Postorivo, D., Nardone, A. M., Avnet, S., Cortelli, P., et al. (2012) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.12.006 · Cited by 26 · see citing works

The visualization of large organized chromatin domains enriched in the H3K9me2 mark within a single chromosome in a single cell

Chen, X., Yammine, S., Shi, C., Tark‐Dame, M., Göndör, A., & OHLSSON, R. I. (2014) · Epigenetics · doi:10.4161/15592294.2014.971633 · Cited by 21 · see citing works

Simultaneous quantification of protein-DNA contacts and transcriptomes in single cellsPreprint

Rooijers, K., Markodimitraki, C. M., Rang, F. J., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/529388 · Cited by 18 · see citing works

Nuclear architecture as an intrinsic regulator of Drosophila female germline stem cell maintenance

Duan, T., Green, N. M., Tootle, T. L., & Geyer, P. (2020) · Current Opinion in Insect Science · doi:10.1016/j.cois.2019.11.007 · Cited by 16 · see citing works

Ageing and rejuvenation of tissue stem cells and their niches

Brunet, A., Goodell, M. A., & Rando, T. A. (2023) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00510-w · Cited by 407 · see citing works

The Cytoskeleton as Regulator of Cell Signaling Pathways

Moujaber, O., & Stochaj, U. (2020) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2019.11.003 · Cited by 158 · see citing works

Nuclear F-Actin Counteracts Nuclear Deformation and Promotes Fork Repair during Replication Stress

Lamm, N., Read, M. N., Nobis, M., Van Ly, D., Page, S. G., Masamsetti, V. P., Timpson, P., Biro, M., & Cesare, A. J. (2020) · Nature Cell Biology · doi:10.1038/s41556-020-00605-6 · Cited by 156 · see citing works

Nuclear envelope remodelling during mitosis

Dey, G., & Baum, B. (2021) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2020.12.004 · Cited by 78 · see citing works

Recent progress in the mechanistic understanding of NET formation in neutrophils

Liu, M., Lyu, X., & Werth, V. P. (2021) · FEBS Journal · doi:10.1111/febs.16036 · Cited by 67 · see citing works

Intramembrane proteolysis at a glance: from signalling to protein degradation

Kühnle, N., Dederer, V., & Lemberg, M. K. (2019) · Journal of Cell Science · doi:10.1242/jcs.217745 · Cited by 62 · see citing works

Structure and unique mechanical aspects of nuclear lamin filaments

Kronenberg‐Tenga, R., & Medalia, O. (2020) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2020.06.017 · Cited by 56 · see citing works

Structural and Mechanical Aberrations of the Nuclear Lamina in Disease

Stiekema, M., van Zandvoort, M. A. M. J., Ramaekers, F. C. S., & Broers, J. L. V. (2020) · Cells · doi:10.3390/cells9081884 · Cited by 54 · see citing works

Dynamic 3D genome reorganization during senescence: defining cell states through chromatin

Shaban, H. A., & Gasser, S. M. (2023) · Cell Death and Differentiation · doi:10.1038/s41418-023-01197-y · Cited by 55 · see citing works

Sinus node dysfunction: current understanding and future directions

Manoj, P., Kim, J. A., Kim, S. J., Li, T., Sewani, M. A., Chelu, M. G., & Li, N. (2022) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00618.2022 · Cited by 53 · see citing works

Viewing Nuclear Architecture through the Eyes of Nocturnal Mammals

Feodorova, Y. N., Falk, M. J., Mirny, L. A., & Solovei, I. V. (2020) · Trends in Cell Biology · doi:10.1016/j.tcb.2019.12.008 · Cited by 49 · see citing works

Polycomb-lamina antagonism partitions heterochromatin at the nuclear periphery

Siegenfeld, A. P., Roseman, S. A., Roh, H., Lue, N. Z., Wagen, C., Zhou, E., Johnstone, S. E., Aryee, M. J., & Liau, B. B. (2022) · Nature Communications · doi:10.1038/s41467-022-31857-5 · Cited by 40 · see citing works

3D spatial genome organization in the nervous system: From development and plasticity to disease

Fujita, Y., Pather, S. R., Ming, G., & Song, H. (2022) · Neuron · doi:10.1016/j.neuron.2022.06.004 · Cited by 37 · see citing works

Nuclear mechanotransduction in stem cells

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Nuclear pore complex-mediated gene expression in Arabidopsis thaliana

Tamura, K. (2020) · Journal of Plant Research · doi:10.1007/s10265-020-01177-0 · Cited by 23 · see citing works

Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference

Lobo, V., Nowak, I., Fernandez, C., Muler, A. I. C., Westholm, J. O., Huang, H., Fabrik, I., Huynh, H. T., Shcherbinina, E. Y., Poyraz, M., et al. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae589 · Cited by 22 · see citing works

Antagonism between H3K27me3 and genome–lamina association drives atypical spatial genome organization in the totipotent embryo

Guerreiro, I. M., Rang, F. J., Kawamura, Y., Kroon-Veenboer, C., Korving, J., Groenveld, F. C., van Beek, R. E., Lochs, S. J. A., Boele, E., Peters, A. H. F. M., et al. (2024) · Nature Genetics · doi:10.1038/s41588-024-01902-8 · Cited by 21 · see citing works

An Epigenetic LINE-1-Based Mechanism in Cancer

Lavia, P., Sciamanna, I., & Spadafora, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314610 · Cited by 20 · see citing works

Regulation of diverse nuclear shapes: pathways working independently, together

Deolal, P., & Mishra, K. (2021) · Communicative & Integrative Biology · doi:10.1080/19420889.2021.1939942 · Cited by 17 · see citing works

PRR14 organizes H3K9me3-modified heterochromatin at the nuclear lamina

Kiseleva, A. A., Cheng, Y.-C., Smith, C. L., Katz, R. A., & Poleshko, A. S. (2023) · Nucleus · doi:10.1080/19491034.2023.2165602 · Cited by 17 · see citing works

Nuclear architecture as an intrinsic regulator of Drosophila female germline stem cell maintenance

Duan, T., Green, N. M., Tootle, T. L., & Geyer, P. (2020) · Current Opinion in Insect Science · doi:10.1016/j.cois.2019.11.007 · Cited by 16 · see citing works

The Genomic Code: A Pervasive Encoding/Molding of Chromatin Structures and a Solution of the “Non‐Coding DNA” Mystery

Bernardi, G. (2019) · BioEssays · doi:10.1002/bies.201900106 · Cited by 15 · see citing works

Reorganization of the nuclear architecture in the Drosophila melanogaster Lamin B mutant lacking the CaaX box

Bondarenko, S. M., & Sharakhov, I. V. (2020) · Nucleus · doi:10.1080/19491034.2020.1819704 · Cited by 15 · see citing works

Chromatin protein complexes involved in gene repression in lamina-associated domains

Manzo, S. G., Mazouzi, A., Leemans, C., van Schaik, T., Neyazi, N., van Ruiten, M. S., Rowland, B. D., Brummelkamp, T. R., & van Steensel, B. (2024) · The EMBO Journal · doi:10.1038/s44318-024-00214-1 · Cited by 14 · see citing works

Drosophila Models Reveal Properties of Mutant Lamins That Give Rise to Distinct Diseases

Walker, S. G., Langland, C. J., Viles, J., Hecker, L. A., & Wallrath, L. L. (2023) · Cells · doi:10.3390/cells12081142 · Cited by 12 · see citing works

CTCF supports preferentially short lamina-associated domains

Kaczmarczyk, L. S., Levi, N., Segal, T., Salmon‐Divon, M., & Gerlitz, G. (2022) · Chromosome Research · doi:10.1007/s10577-022-09686-5 · Cited by 12 · see citing works

Liquid–liquid phase separation of lamin drives altered chromatin organization in cardiomyopathic mutations of lamin A

Nath, S., Dutta, S., Sarkar, S. D., Sengupta, D., Mitra, M. K., & Sengupta, K. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf615 · Cited by 10 · see citing works

Brain Cell Type-Specific Nuclear Proteomics Is Imperative to Resolve Neurodegenerative Disease Mechanisms

Nelson, R. S., Dammer, E. B., Santiago, J. V., Seyfried, N. T., & Rangaraju, S. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.902146 · Cited by 9 · see citing works

“Block and lock” viral integration sites in persons with drug-free control of HIV-1 infection

Bone, B., & Lichterfeld, M. D. (2024) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000845 · Cited by 8 · see citing works

A Glimpse into Chromatin Organization and Nuclear Lamina Contribution in Neuronal Differentiation

Martino, S., Carollo, P. S., & Barra, V. (2023) · Genes · doi:10.3390/genes14051046 · Cited by 7 · see citing works

The secret life of chromatin tethers

Kiseleva, A. A., & Poleshko, A. S. (2023) · FEBS Letters · doi:10.1002/1873-3468.14685 · Cited by 7 · see citing works

A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and germline stem cell fatePreprint

Chavan, A., Isenhart, R. L., Nguyen, S. C., Kotb, N. M., Harke, J., Sintsova, A., Ulukaya, G. B., Uliana, F., Ashiono, C., Kutay, U., et al. (2024) · Genes & Development · doi:10.1101/gad.351424.123 · Cited by 7 · see citing works

Alterations in Genome Organization in Lymphoma Cell Nuclei due to the Presence of the t(14;18) Translocation

Garimberti, E., Federico, C., Ragusa, D., Bruno, F., Saccone, S., Bridger, J. M., & Tosi, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042377 · Cited by 6 · see citing works

Genome organization in cardiomyocytes expressing mutated A-type lamins

Kervella, M., Jahier, M., Méli, A. C., & Muchir, A. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1030950 · Cited by 5 · see citing works

Enhancers on the edge — how the nuclear envelope controls gene regulatory elements

Czapiewski, R., & Schirmer, E. C. (2024) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2024.102234 · Cited by 5 · see citing works

H3K27me3 dictates atypical genome-nuclear lamina interactions and allelic asymmetry during early embryogenesisPreprint

Guerreiro, I. M., Rang, F. J., Kawamura, Y., Groenveld, F. C., van Beek, R. E., Lochs, S. J. A., Boele, E., Peters, A. H. F. M., & Kind, J. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.06.527307 · Cited by 5 · see citing works

High-Efficiency Enrichment by Saturating Nanoliters of Protein Affinity Media

Raval, S., Douglas, P., Laurent, D., Khan, M. F., Lees‐Miller, S. P., & Schriemer, D. C. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.3c01736 · Cited by 4 · see citing works

Genetic approaches to revealing the principles of nuclear architecture

Askjaer, P., & Harr, J. C. (2020) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2020.11.001 · Cited by 4 · see citing works

The probability of chromatin to be at the nuclear lamina has no systematic effect on its transcription level in fruit flies

Afanasyev, A. Y., Kim, Y., Tolokh, I. S., Sharakhov, I. V., & Onufriev, A. V. (2024) · Epigenetics & Chromatin · doi:10.1186/s13072-024-00528-8 · Cited by 4 · see citing works

Baf-mediated transcriptional regulation of teashirt is essential for the development of neural progenitor cell lineages

Ko, B. S., Han, M., Kwon, M. J., Gon, D., Ji, Y., Park, E. S., Jeon, M. J., Kim, S., Lee, K., Choi, Y. H., et al. (2024) · Experimental & Molecular Medicine · doi:10.1038/s12276-024-01169-3 · Cited by 3 · see citing works

Reorganization of H3K9me2-modified chromatin regions during mouse embryonic development

Fulmer, D. B., Shields, E. J., Poleshko, A. S., Epstein, J. A., & Smith, C. L. (2025) · Developmental Biology · doi:10.1016/j.ydbio.2025.09.005 · Cited by 2 · see citing works

Regulation and dysregulation of spatial chromatin structure in the central nervous system

Fujita, Y. (2021) · Anatomical Science International · doi:10.1007/s12565-020-00567-7 · Cited by 2 · see citing works

Distinct Classes of Lamin-Associated Domains are Defined by Differential Patterns of Repressive Histone MethylationPreprint

Martin, C. J., Nagarajan, P., Oser, E. A., Popova, L. V., & Parthun, M. R. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.20.629719 · Cited by 2 · see citing works

The Mutated p.H222P A-type Lamins Drive Loxl2-Mediated Extracellular Matrix Remodeling in Both Patient-Derived Cardiomyocytes and Mouse Models of Dilated CardiomyopathyPreprint

Kervella, M., Peccate, C., Guesmia, Z., Grandi, F. C., Mougenot, N., Forand, A., Charrabi, A., Brochier, G., Andriantsitohaina, R., Méli, A. C., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.10.632312 · Cited by 2 · see citing works

Distinct classes of lamina-associated domains are defined by differential patterns of repressive histone methylationPreprint

Martin, C. J., Oser, E. A., Nagarajan, P., Popova, L. V., Sunkel, B. D., Stanton, B. Z., & Parthun, M. R. (2025) · Genome Research · doi:10.1101/gr.280380.124 · Cited by 2 · see citing works

State‐of‐the‐art in transposable element modulation affected by drugs in malignant prostatic cancer cells

Terrazzan, A., Vanini, R., Ancona, P., Bianchi, N., Taccioli, C., & Aguiari, G. (2024) · Journal of Cellular Biochemistry · doi:10.1002/jcb.30557 · Cited by 1 · see citing works

A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and germline stem cell fatePreprint

Chavan, A., Isenhart, R. L., Nguyen, S. C., Kotb, N. M., Harke, J., Sintsova, A., Ulukaya, G. B., Uliana, F., Ashiono, C., Kutay, U., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.17.567611 · Cited by 1 · see citing works

A multiscale chromatin collapse underlies vascular pathology in Hutchinson–Gilford progeria syndromePreprint

Ngubo, M., Ahuja, N., Karimpour, R., Shrestha, A., Hendzel, M. J., Perkins, T. J., & Stanford, W. L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.11.693713

Lamin A/C maintains genome topology and regulates transcriptional programs essential for virus-driven B cell activationPreprint

Caruso, L. B., Maestri, D., Kossenkov, A., Goldman, A. R., Cassel, J., Soldan, S. S., Lieberman, P., & Tempera, I. (2026) · bioRxiv · doi:10.64898/2026.01.12.699161

Simtuzumab Attenuates Loxl2-Mediated Extracellular Matrix Remodeling and Preserves Cardiac Function in LMNA Mutation-Induced Dilated Cardiomyopathy

Kervella, M., Behrens, C. S., Peccate, C., Guesmia, Z., Grandi, F. C., Mougenot, N., Forand, A., Charrabi, A., Brochier, G., Andriantsitohaina, R., et al. (2026) · Circulation Heart Failure · doi:10.1161/circheartfailure.125.013806

ECHOS enables spatial epigenome profiling at subcellular resolutionPreprint

Cao, Q., Xu, Q., Ueda, Y., Rajachandran, S., Sharma, M., Zhang, X., Mahendroo, M., Grow, E. J., & Chen, H. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.26.714421

Interaction between telomeres and the nuclear envelope in human cells : dynamics and molecular mechanism

Kychygina, G. (2019) · doi:10.70675/257216a4zfec4z40ccza35bz81fab5ab7e1e

Mécanisme de génération de forces par les cellules apoptotiques lors de la morphogenèse de la drosophile

Rayer, M. (2019) · doi:10.70675/7f91c556z596az4ca1zaa62z90ed3e225979

Régulation et rôle de la compaction de la chromatine dans des cellules pluripotentes et lors de la différentiation

Dupont, C. (2020) · doi:10.70675/8ea2b02bz2e4fz4ee2za3e9z528116d43d56

Spatiotemporal distribution of ploidy levels and ploidy specific transcriptome during Tomato fruit development

Tourdot, É. (2021) · doi:10.70675/4a52ccedza6fbz468dzbc9bz3760ade033f3

Emerging Roles of Phase Separation at Nuclear Envelope

Tang, Y. (2026) · Journal of Cellular Signaling · doi:10.33696/signaling.7.150

Ionic Exposure History Shapes Inner Nuclear Membrane Voltage and Chromatin Texture ResponsesPreprint

Sediqi, H., Mathews, J., de Nola, G., Lytton‐Jean, A. K. R., & Levin, M. G. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.23.733978

Multiscale spatial analysis implicates chromosomal metaloops in gene patterning across the Drosophila brainPreprint

Patel, A. L., Venkatesh, A. R., Borjigin, T., Li, X., Levine, M. S., & Boettiger, A. N. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.02.748911

The role of linker histone H1.2 in tumor progression, resistance, and clinical translation

Zhou, J., Shi, J., Zheng, L., Huang, K., & Li, Y. (2026) · Epigenomics · doi:10.1080/17501911.2026.2740944

Role of the Nuclear Lamina in Genome Organization and Gene ExpressionPreprint

Peric‐Hupkes, D., & van Steensel, B. (2010) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2010.75.014 · Cited by 81 · see citing works

Mechanisms and dynamics of nuclear lamina–genome interactions

Amendola, M., & van Steensel, B. (2014) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2014.03.003 · Cited by 112 · see citing works

Nuclear lamina maintains global spatial organization of chromatin in Drosophila cultured cells

Ulianov, S. V., Doronin, S. A., Khrameeva, E. E., Kos, P. I., Starikov, S. S., Galitsyna, A. A., Luzhin, A. V., Gelfand, M. S., Chertovich, A. V., Razin, S. V., et al. (2018) · IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · doi:10.1109/bibm.2018.8621123 · Cited by 1 · see citing works

Role of lamins in 3D genome organization and global gene expression

Kim, Y., Zheng, X., & Zheng, Y. (2019) · Nucleus · doi:10.1080/19491034.2019.1578601 · Cited by 32 · see citing works

Attach and stretch: Emerging roles for genome–lamina contacts in shaping the 3D genome

Rullens, P. M. J., & Kind, J. (2020) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2020.11.006 · Cited by 26 · see citing works