Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

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High-Resolution Profiling of Histone Methylations in the Human Genome

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Topological domains in mammalian genomes identified by analysis of chromatin interactions

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Spatial partitioning of the regulatory landscape of the X-inactivation centre

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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

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Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)

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Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

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Condensin-driven remodelling of X chromosome topology during dosage compensation

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Topologically associating domains are stable units of replication-timing regulation

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3D structures of individual mammalian genomes studied by single-cell Hi-C

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LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation

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Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging

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Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

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Transcriptional repression mediated by repositioning of genes to the nuclear lamina

Reddy, K. L., Zullo, J., Bertolino, E., & Singh, H. (2008) · Nature · doi:10.1038/nature06727 · Cited by 785 · see citing works

Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions

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Single-Cell Dynamics of Genome-Nuclear Lamina Interactions

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Biogenesis and function of nuclear bodies

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Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains

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Characterization of the Drosophila melanogaster genome at the nuclear lamina

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Nuclear Membrane Proteins with Potential Disease Links Found by Subtractive Proteomics

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Transcription upregulation via force-induced direct stretching of chromatin

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Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

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CTCF-mediated functional chromatin interactome in pluripotent cells

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Step-wise methylation of histone H3K9 positions heterochromatin at the nuclear periphery

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Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

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Long-Range Directional Movement of an Interphase Chromosome Site

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Lamins: Nuclear Intermediate Filament Proteins with Fundamental Functions in Nuclear Mechanics and Genome Regulation

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CTCF and Cohesin in Genome Folding and Transcriptional Gene Regulation

Merkenschlager, M., & Nora, E. P. (2016) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-083115-022339 · Cited by 505 · see citing works

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

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Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells

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Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

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DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina

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Nucleoporins Directly Stimulate Expression of Developmental and Cell-Cycle Genes Inside the Nucleoplasm

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A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence

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Initial Genomics of the Human Nucleolus

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On the occurrence of a fibrous lamina on the inner aspect of the nuclear envelope in certain cells of vertebrates

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Nuclear Aggregation of Olfactory Receptor Genes Governs Their Monogenic Expression

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Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation

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Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins

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High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli

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Chromatin Position Effects Assayed by Thousands of Reporters Integrated in Parallel

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Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells

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Accessorizing and anchoring the LINC complex for multifunctionality

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The pluripotent genome in three dimensions is shaped around pluripotency factors

de Wit, E., Bouwman, B. A. M., Zhu, Y. K., Klous, P., Splinter, E., Verstegen, M. J. A. M., Krijger, P. H. L., Festuccia, N., Nora, E. P., Welling, M., et al. (2013) · Nature · doi:10.1038/nature12420 · Cited by 263 · see citing works

Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing

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Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells

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Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy

Shimi, T., Kittisopikul, M., Tran, J. R., Goldman, A. E., Adam, S. A., Zheng, Y., Jaqaman, K., & Goldman, R. D. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e15-07-0461 · Cited by 247 · see citing works

Lamins at the crossroads of mechanosignalingPreprint

Osmanagic‐Myers, S., Dechat, T., & Foisner, R. (2015) · Genes & Development · doi:10.1101/gad.255968.114 · Cited by 230 · see citing works

Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos

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Nuclear position dictates DNA repair pathway choice

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A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alphaPreprint

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Nuclear pore proteins and the control of genome functionsPreprint

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Caenorhabditis elegans chromosome arms are anchored to the nuclear membrane via discontinuous association with LEM-2

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Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis

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The nuclear envelope LEM-domain protein emerin

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Lamin A/C-promoter interactions specify chromatin state–dependent transcription outcomesPreprint

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The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencingPreprint

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HSP70 Transgene Directed Motion to Nuclear Speckles Facilitates Heat Shock Activation

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The Nuclear Envelope Protein Emerin Binds Directly to Histone Deacetylase 3 (HDAC3) and Activates HDAC3 Activity

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Age-Associated Loss of Lamin-B Leads to Systemic Inflammation and Gut Hyperplasia

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Nucleoporin-mediated regulation of cell identity genesPreprint

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G9a selectively represses a class of late-replicating genes at the nuclear periphery

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Lamin B receptor

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Developmentally Regulated Subnuclear Genome Reorganization Restricts Neural Progenitor Competence in Drosophila

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A-type Lamins Form Distinct Filamentous Networks with Differential Nuclear Pore Complex Associations

Xie, W., Chojnowski, A., Boudier, T., Lim, J., Ahmed, S., Ser, Z., Stewart, C. L., & Burke, B. E. (2016) · Current Biology · doi:10.1016/j.cub.2016.07.049 · Cited by 147 · see citing works

PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription

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The B-type lamin is required for somatic repression of testis-specific gene clusters

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An EDMD Mutation in C. elegans Lamin Blocks Muscle-Specific Gene Relocation and Compromises Muscle Integrity

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Transcription factories: genetic programming in three dimensions

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Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery

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The role ofDrosophilaLamin C in muscle function and gene expression

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β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications

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Alterations of nuclear envelope and chromatin organization in mandibuloacral dysplasia, a rare form of laminopathy

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The Insulator Protein SU(HW) Fine-Tunes Nuclear Lamina Interactions of the Drosophila Genome

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Nongenetic functions of the genome

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The Human Protein PRR14 Tethers Heterochromatin to the Nuclear Lamina during Interphase and Mitotic Exit

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Nuclear lamins are not required for lamina‐associated domain organization in mouse embryonic stem cells

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Barrier to Autointegration Factor (BANF1): interwoven roles in nuclear structure, genome integrity, innate immunity, stress responses and progeria

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Differences in centromere positioning of cycling and postmitotic human cell types

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Stochastic genome-nuclear lamina interactions

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Distinct features of lamin A-interacting chromatin domains mapped by ChIP-sequencing from sonicated or micrococcal nuclease-digested chromatin

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Subnuclear segregation of genes and core promoter factors in myogenesisPreprint

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Lamina-associated polypeptide (LAP)2α and nucleoplasmic lamins in adult stem cell regulation and disease

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Characterization and dynamics of pericentromere-associated domains in micePreprint

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