Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 45

The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.

The evolution of MDM2 family genes

Momand, Jamil, Villegas, Alberto, Belyi, Vladimir A.·2011·Gene
DOI 10.1016/j.gene.2011.06.030
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.gene.2011.06.030

Cites

16 of 16 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 16 references

Research works printed but not linked: 52

  1. Altschul, 1997, Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Res., 25, 3389, 10.1093/nar/25.17.3389 · DOI · Paper page
  2. Balint, 1996, Increased rate of transcription contributes to elevated expression of the mutant p53 gene in Burkitt's lymphoma cells, Cancer Res., 56, 1648
  3. Belyi, 2010, The origins and evolution of the p53 family of genes, Cold Spring Harb. Perspect. Biol., 2, a001198, 10.1101/cshperspect.a001198 · DOI · Paper page
  4. Bergamaschi, 2003, iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human, Nat. Genet., 33, 162, 10.1038/ng1070 · DOI · Paper page
  5. Brandt, 2009, Conservation of DNA-binding specificity and oligomerisation properties within the p53 family, BMC Genomics, 10, 628, 10.1186/1471-2164-10-628 · DOI · Paper page
  6. Cahilly-Snyder, 1987, Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line, Somat. Cell Mol. Genet., 13, 235, 10.1007/BF01535205 · DOI · Paper page
  7. Calabro, 2002, The human MDM2 oncoprotein increases the transcriptional activity and the protein level of the p53 homolog p63, J. Biol. Chem., 277, 2674, 10.1074/jbc.M107173200 · DOI
  8. Derry, 2001, Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance, Science, 294, 591, 10.1126/science.1065486 · DOI · Paper page
  9. Eitel, 2011, New insights into placozoan sexual reproduction and development, PLoS One, 6, e19639, 10.1371/journal.pone.0019639 · DOI
  10. el-Deiry, 1993, WAF1, a potential mediator of p53 tumor suppression, Cell, 75, 817, 10.1016/0092-8674(93)90500-P · DOI · Paper page
  11. Fakharzadeh, 1991, Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line, EMBO J., 10, 1565, 10.1002/j.1460-2075.1991.tb07676.x · DOI · Paper page
  12. Fang, 2000, MDM2 is a RING finger-dependent ubiquitin protein ligase for itself and p53, J. Biol. Chem., 275, 8945, 10.1074/jbc.275.12.8945 · DOI · Paper page
  13. Flicek, 2011, Ensembl 2011, Nucleic Acids Res., 39, D800, 10.1093/nar/gkq1064 · DOI · Paper page
  14. Glazko, 2003, Estimation of divergence times for major lineages of primate species, Mol. Biol. Evol., 20, 424, 10.1093/molbev/msg050 · DOI · Paper page
  15. Haupt, 1997, MDM2 promotes the rapid degradation of p53, Nature, 387, 296, 10.1038/387296a0 · DOI · Paper page
  16. Hock, 2010, Regulation of the p53 pathway by ubiquitin and related proteins, Int. J. Biochem. Cell Biol., 42, 1618, 10.1016/j.biocel.2010.06.011 · DOI
  17. Hubbard, 2009, Ensembl 2009, Nucleic Acids Res., 37, D690, 10.1093/nar/gkn828 · DOI · Paper page
  18. Hunter, 2009, InterPro: the integrative protein signature database, Nucleic Acids Res., 37, D211, 10.1093/nar/gkn785 · DOI · Paper page
  19. Jin, 2000, Identification and characterization of a p53 homologue in Drosophila melanogaster, Proc. Natl. Acad. Sci. U.S.A., 97, 7301, 10.1073/pnas.97.13.7301 · DOI · Paper page
  20. Kadakia, 2001, Regulation of p63 function by MDM2 and MdmX, DNA Cell Biol., 20, 321, 10.1089/10445490152122433 · DOI
  21. Kallen, 2009, Crystal structures of human MdmX (HdmX) in complex with p53 peptide analogues reveal surprising conformational changes, J. Biol. Chem., 284, 8812, 10.1074/jbc.M809096200 · DOI
  22. Kojima, 2001, Analysis of molecular interactions of the p53-family p51(p63) gene products in a yeast two-hybrid system: homotypic and heterotypic interactions and association with p53-regulatory factors, Biochem. Biophys. Res. Commun., 281, 1170, 10.1006/bbrc.2001.4486 · DOI
  23. Kubbutat, 1997, Regulation of p53 stability by MDM2, Nature, 387, 299, 10.1038/387299a0 · DOI · Paper page
  24. Lane, 2010, MDM2 and p53 are highly conserved from placozoans to man, Cell Cycle, 9, 540, 10.4161/cc.9.3.10516 · DOI
  25. Lane, 2010, The MDM2 and p53 genes are conserved in the Arachnids, Cell Cycle, 9, 748, 10.4161/cc.9.4.10616 · DOI
  26. Larkin, 2007, Clustal W and Clustal X version 2.0, Bioinformatics, 23, 2947, 10.1093/bioinformatics/btm404 · DOI · Paper page
  27. Laurie, 2006, Inactivation of the p53 pathway in retinoblastoma, Nature, 444, 61, 10.1038/nature05194 · DOI · Paper page
  28. Liang, 2010, HDM4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis, Mod. Pathol., 23, 381, 10.1038/modpathol.2009.170 · DOI
  29. Little, 2001, Hdmx and MDM2 can repress transcription activation by p53 but not by p63, Oncogene, 20, 4576, 10.1038/sj.onc.1204615 · DOI
  30. Margoliash, 1963, Primary structure and evolution of Cytochrome C, Proc. Natl. Acad. Sci. U.S.A., 50, 672, 10.1073/pnas.50.4.672 · DOI · Paper page
  31. Mavinahalli, 2010, Differences in the transactivation domains of p53 family members: a computational study, BMC Genomics, 11, S5, 10.1186/1471-2164-11-S1-S5 · DOI
  32. Miller, 2005, Animal evolution: the enigmatic phylum placozoa revisited, Curr. Biol., 15, R26, 10.1016/j.cub.2004.12.016 · DOI
  33. Miller, 2007, 28-way vertebrate alignment and conservation track in the UCSC Genome Browser, Genome Res., 17, 1797, 10.1101/gr.6761107 · DOI · Paper page
  34. Momand, 1992, The MDM-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation, Cell, 69, 1237, 10.1016/0092-8674(92)90644-R · DOI · Paper page
  35. Momand, 1998, The MDM2 gene amplification database, Nucleic Acids Res., 26, 3453, 10.1093/nar/26.15.3453 · DOI · Paper page
  36. Murphy, 2007, Using genomic data to unravel the root of the placental mammal phylogeny, Genome Res., 17, 413, 10.1101/gr.5918807 · DOI · Paper page
  37. Muttray, 2010, An invertebrate mdm homolog interacts with p53 and is differentially expressed together with p53 and ras in neoplastic Mytilus trossulus haemocytes, Comp. Biochem. Physiol. B Biochem. Mol. Biol., 156, 298, 10.1016/j.cbpb.2010.04.008 · DOI
  38. Nedelcu, 2007, Early diversification and complex evolutionary history of the p53 tumor suppressor gene family, Dev. Genes Evol., 217, 801, 10.1007/s00427-007-0185-9 · DOI
  39. Needleman, 1970, A general method applicable to the search for similarities in amino acid sequence of two proteins, J. Mol. Biol., 48, 443, 10.1016/0022-2836(70)90057-4 · DOI · Paper page
  40. Pazos, 2008, Protein co-evolution, co-adaptation and interactions, EMBO J., 27, 2648, 10.1038/emboj.2008.189 · DOI · Paper page
  41. Popowicz, 2007, Molecular basis for the inhibition of p53 by Mdmx, Cell Cycle, 6, 2386, 10.4161/cc.6.19.4740 · DOI
  42. Prasad, 2008, Confirming the phylogeny of mammals by use of large comparative sequence data sets, Mol. Biol. Evol., 25, 1795, 10.1093/molbev/msn104 · DOI · Paper page
  43. Putnam, 2008, The amphioxus genome and the evolution of the chordate karyotype, Nature, 453, 1064, 10.1038/nature06967 · DOI · Paper page
  44. Rice, 2000, EMBOSS: the European Molecular Biology Open Software Suite, Trends Genet., 16, 276, 10.1016/S0168-9525(00)02024-2 · DOI · Paper page
  45. Rutkowski, 2010, Phylogeny and function of the invertebrate p53 superfamily, Cold Spring Harb. Perspect. Biol., 2, a001131, 10.1101/cshperspect.a001131 · DOI
  46. Singh, 2007, Hetero-oligomerization with MdmX rescues the ubiquitin/Nedd8 ligase activity of RING finger mutants of MDM2, J. Biol. Chem., 282, 10901, 10.1074/jbc.M610879200 · DOI
  47. Srivastava, 2008, The Trichoplax genome and the nature of placozoans, Nature, 454, 955, 10.1038/nature07191 · DOI · Paper page
  48. Tanimura, 1999, MDM2 interacts with MDMX through their RING finger domains, FEBS Lett., 447, 5, 10.1016/S0014-5793(99)00254-9 · DOI · Paper page
  49. Uldrijan, 2007, An essential function of the extreme C-terminus of MDM2 can be provided by MDMX, EMBO J., 26, 102, 10.1038/sj.emboj.7601469 · DOI · Paper page
  50. Weber, 1999, Nucleolar Arf sequesters MDM2 and activates p53, Nat. Cell Biol., 1, 20, 10.1038/8991 · DOI · Paper page
  51. Yu, 2006, Solution structure of the C4 zinc finger domain of HDM2, Protein Sci., 15, 384, 10.1110/ps.051927306 · DOI
  52. Zdzalik, 2010, Interaction of regulators MDM2 and Mdmx with transcription factors p53, p63 and p73, Cell Cycle, 9, 4584, 10.4161/cc.9.22.13871 · DOI

Cited by

See all 45

Metadata

Authors
Momand, J., Villegas, A., & Belyi, V. A.
Venue
Gene
Publisher
Elsevier BV
Published
2011-10
Volume
486
Issue
1-2
Pages
23-30
ISSN
0378-1119
DOI
10.1016/j.gene.2011.06.030
Cited by
45
References
16
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: The evolution of MDM2 family genes. https://app.cochat.ai/papers/10.1016/j.gene.2011.06.030
The paper
Momand, J., Villegas, A., & Belyi, V. A. (2011). The evolution of MDM2 family genes. Gene. https://doi.org/10.1016/j.gene.2011.06.030

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.