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Cited by 158

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

NEDD4: The founding member of a family of ubiquitin-protein ligases

Open access
Boase, Natasha Anne, Kumar, Sharad·2015·Gene

Abstract

Ubiquitination plays a crucial role in regulating proteins post-translationally. The focus of this review is on NEDD4, the founding member of the NEDD4 family of ubiquitin ligases that is evolutionarily conserved in eukaryotes. Many potential substrates of NEDD4 have been identified and NEDD4 has been shown to play a critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumour suppressor PTEN. In this review we will discuss the diverse pathways in which NEDD4 is involved, and the patho-physiological significance of this important ubiquitin ligase.

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Metadata

Authors
Boase, N. A., & Kumar, S.
Venue
Gene
Publisher
Elsevier BV
Published
2015-02
Volume
557
Issue
2
Pages
113-122
ISSN
0378-1119 (ISSN-L)
OpenAlex
W2029439166
Cited by
158
References
6
FWCI
3.65
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: NEDD4: The founding member of a family of ubiquitin-protein ligases. https://app.cochat.ai/papers/10.1016/j.gene.2014.12.020
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Boase, N. A., & Kumar, S. (2015). NEDD4: The founding member of a family of ubiquitin-protein ligases. Gene. https://doi.org/10.1016/j.gene.2014.12.020

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.