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Depression and anxiety among high-risk obstetric inpatients
Open accessAbstract
Objective To assess the following among women hospitalized antenatally due to high-risk pregnancies: (1) rates of depression symptoms and anxiety symptoms, (2) changes in depression symptoms and anxiety symptoms and, (3) rates of mental health treatment.Methods Sixty-two participants hospitalized for high-risk obstetrical complications completed the Edinburgh Postnatal Depression Scale (EPDS), Generalized Anxiety Disorder 7-item scale (GAD-7) and Short-Form 12 weekly until delivery or discharge, and once postpartum.Results Average length of total hospital stay was 8.3 ± 7.6 days for women who completed an initial admission survey (n = 62) and 16.3 ± 8.9 (n = 34), 25.4 ± 10.2 (n = 17) and 35 ± 10.9 days (n = 9) for those who completed 2, 3 and 4 surveys, respectively. EPDS was ≥ 10 in 27% (n=17) and GAD-7 was ≥ 10 in 13% (n = 8) of participants at initial survey. Mean anxiety (4.2 ± 6.5 vs. 5.2 ± 5.1, p = .011) and depression (4.4 ± 5.6 vs. 6.9 ± 4.8, p = .011) scores were lower postpartum compared to initial survey. Past mental health diagnosis predicted depression symptoms [odds ratio (OR) = 4.54; 95% confidence interval (CI) 1.91-7.17] and anxiety symptoms (OR = 5.95; 95% CI 3.04-8.86) at initial survey; however, 21% (n = 10) with no diagnostic history had EPDS ≥ 10. Five percent (n = 3) received mental health treatment during pregnancy.Conclusion Hospitalized high-risk obstetrical patients may commonly experience depression symptoms and/or anxiety symptoms and not receive treatment. A history of mental health treatment or diagnosis was associated with depression symptoms or anxiety symptoms in pregnancy. Of women with an EPDS ≥ 10, > 50% did not report a past mental health diagnosis.
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“our study (n = 4161) is the largest to date demonstrating an increased risk of depression symptoms postpartum compared to the general obstetric population.”
From Factors associated with postpartum depression symptoms following antepartum hospitalization (2026) · cites this paper as [49]
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“The high underreporting of pregnant women with prenatal depression and anxiety disorders is consistent with findings from other studies.”
From Acceptance, experiences, and needs of hospitalized pregnant women toward an electronic mindfulness-based intervention: A pilot mixed-methods study (2022) · cites this paper as [62]
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“Byatt et al. reported that despite the high prevalence of depression (26.9%) and anxiety symptoms (12.6%), high-risk inpatient pregnant women rarely receive psychological screening and/ or treatment (5%) (62).”
From Acceptance, experiences, and needs of hospitalized pregnant women toward an electronic mindfulness-based intervention: A pilot mixed-methods study (2022) · cites this paper as [62]
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Metadata
- Authors
- Byatt, N., Hicks-Courant, K., Davidson, A., Levesque, R., Mick, E., Allison, J., & Moore Simas, T. A.
- Affiliations
- University of Massachusetts Chan Medical School (US)
- University of Chicago Medical Center (US)
- Corresponding author
- Byatt, Nancy
- Venue
- General Hospital Psychiatry
- Publisher
- Elsevier BV
- Published
- 2014-11
- Volume
- 36
- Issue
- 6
- Pages
- 644-649
- ISSN
- 0163-8343 (ISSN-L)
- PMC
- PMC4399814
- OpenAlex
- W2089442606
- Cited by
- 104
- References
- 43
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 5 · 2023: 10 · 2022: 16 · 2021: 11 · 2020: 10 · 2019: 12 · 2018: 11 · 2017: 4 · 2016: 7 · 2015: 6
- FWCI
- 5.61
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- General Hospital Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Center for Research Resources
- National Center for Advancing Translational Sciences, National Institutes of Health (NIH) (KL2TR000160)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and Neonatal Healthcare
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Keywords
- antenatal depression, prenatal anxiety, high-risk pregnancy, postpartum mental health, Edinburgh Postnatal Depression Scale, GAD-7, psychotherapy, pregnancy complications
- MeSH terms
- Adult, Anxiety, Depression, Female, Hospitalization, Humans, Inpatients, Length of Stay, Pregnancy, Pregnancy Complications, Prospective Studies, Surveys and Questionnaires, Cohort Studies, Pregnancy, High-Risk, Postpartum Period, Young Adult, Peripartum Period
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