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Advances in drug delivery systems, challenges and future directions
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“DDS have been specifically established to tackle these issues, as it utilizes these issues as means of targeting tumor sites, which provides efficiency, safety, and site-specific drug delivery [28]. It brings about high local drug concentrations, extended drug retention on tumors, and minimal off-target side effects.”
From Advances in green-synthesized magnetic nanoparticles for targeted cancer therapy: mechanisms, applications, and future perspectives (2026) · cites this paper as [26]
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The evolution of commercial drug delivery technologies
Vargason, A. M., Anselmo, A. C., & Mitragotri, S. (2021) · Nature Biomedical Engineering · doi:10.1038/s41551-021-00698-w · Cited by 1,361 · cited 2×
“Furthermore, it improves drug solubility, target site accumulation, efficacy, pharmacological activity, pharmacokinetic properties, patient acceptance, and compliance, and reduces drug toxicity [2].”
BackgroundCombination therapy based on nano codelivery for overcoming cancer drug resistance
Wang, H., & Huang, Y. (2020) · Medicine in Drug Discovery · doi:10.1016/j.medidd.2020.100024 · Cited by 115
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El-khawaga, A. M., Youssef, O. I., El-dydamoni, O. A., Ragab, W. M., & Mohammed, R. A. E. (2026) · European Journal of Medical Research · doi:10.1186/s40001-025-03804-9 · Cited by 14
Noureen, S., Noreen, S., Batool, F., Ghumman, S. A., Hasan, S., Aslam, S., & Ahmed, N. (2026) · RSC Pharmaceutics · doi:10.1039/d5pm00263j
Metadata
- Authors
- Ezike, T. C., Okpala, U. S., Onoja, U. L., Nwike, C. P., Ezeako, E. C., Okpara, O. J., Okoroafor, C. C., Eze, S. C., Kalu, O. L., Odoh, E. C., Nwadike, U. G., Ogbodo, J. O., Umeh, B. U., Ossai, E. C., & Nwanguma, B. C.
- Venue
- Heliyon
- Publisher
- Elsevier BV
- Published
- 2023-06
- Volume
- 9
- Issue
- 6
- Pages
- e17488
- ISSN
- 2405-8440
- PMC
- PMC10320272
- Cited by
- 1,040
- References
- 2
- Language
- en
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