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Cited by 789

The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.

Recognizing COVID-19–related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management

Open access
Siripanthong, Bhurint, Nazarian, Saman, Muser, Daniele, Deo, Rajat, Santangeli, Pasquale, Khanji, Mohammed Y., Cooper, Leslie T., Chahal, C. Anwar A.·2020·Heart Rhythm

Abstract

Human coronavirus-associated myocarditis is known, and a number of coronavirus disease 19 (COVID-19)–related myocarditis cases have been reported. The pathophysiology of COVID-19–related myocarditis is thought to be a combination of direct viral injury and cardiac damage due to the host’s immune response. COVID-19 myocarditis diagnosis should be guided by insights from previous coronavirus and other myocarditis experience. The clinical findings include changes in electrocardiogram and cardiac biomarkers, and impaired cardiac function. When cardiac magnetic resonance imaging is not feasible, cardiac computed tomographic angiography with delayed myocardial imaging may serve to exclude significant coronary artery disease and identify myocardial inflammatory patterns. Because many COVID-19 patients have cardiovascular comorbidities, myocardial infarction should be considered. If the diagnosis remains uncertain, an endomyocardial biopsy may help identify active cardiac infection through viral genome amplification and possibly refine the treatment risks of systemic immunosuppression. Arrhythmias are not uncommon in COVID-19 patients, but the pathophysiology is still speculative. Nevertheless, clinicians should be vigilant to provide prompt monitoring and treatment. The long-term impact of COVID-19 myocarditis, including the majority of mild cases, remains unknown.

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Metadata

Authors
Siripanthong, B., Nazarian, S., Muser, D., Deo, R., Santangeli, P., Khanji, M. Y., Cooper, L. T., & Chahal, C. A. A.
Venue
Heart Rhythm
Publisher
Elsevier BV
Published
2020-09
Volume
17
Issue
9
Pages
1463-1471
ISSN
1547-5271 (ISSN-L)
OpenAlex
W3023630330
Cited by
789
References
51
FWCI
93.29
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Recognizing COVID-19–related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management. https://app.cochat.ai/papers/10.1016/j.hrthm.2020.05.001
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Siripanthong, B., Nazarian, S., Muser, D., Deo, R., Santangeli, P., Khanji, M. Y., Cooper, L. T., & Chahal, C. A. A. (2020). Recognizing COVID-19–related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management. Heart Rhythm. https://doi.org/10.1016/j.hrthm.2020.05.001

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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