The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Insect MicroRNAs: Biogenesis, expression profiling and biological functions
Open accessAbstract
MicroRNAs (miRNA) are a class of endogenous regulatory RNA molecules 21-24 nucleotides in length that modulate gene expression at the post-transcriptional level via base pairing to target sites within messenger RNAs (mRNA). Typically, the miRNA “seed sequence” (nucleotides 2-8 at the 5′ end) binds complementary seed match sites within the 3′ untranslated region of mRNAs, resulting in either translational inhibition or mRNA degradation. MicroRNAs were first discovered in Caenorhabditis elegans and were shown to be involved in the timed regulation of developmental events. Since their discovery in the 1990s, thousands of potential miRNAs have since been identified in various organisms through small RNA cloning methods and/or computational prediction, and have been shown to play functionally important roles of gene regulation in invertebrates, vertebrates, plants, fungi and viruses. Numerous functions of miRNAs identified in Drosophila melanogaster have demonstrated a great significance of these regulatory molecules. However, elucidation of miRNA roles in non-drosophilid insects presents a challenging and important task.
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Cites
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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
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Combinatorial microRNA target predictions
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“…isotope labeling with amino acids in cell culture or SILAC is a highthroughput method for quantitative proteomics, and can be used to assess the effect of a miRNA on the proteome by overexpressing or knocking down a miRNA of interest (Baek et al., 2008; Selbach et al., 2008; Yang et al., 2010).”
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Cited by
Regulatory Pathways Controlling Female Insect Reproduction
Roy, S., Saha, T. T., Zou, Z., & Raikhel, A. S. (2018) · Annual Review of Entomology · doi:10.1146/annurev-ento-020117-043258 · Cited by 567
Self-citationIftikhar, H., & Carney, G. E. (2016) · BioEssays · doi:10.1002/bies.201500130 · Cited by 87
Expression profile of microRNAs in porcine alveolar macrophages after Toxoplasma gondii infection
Li, S., Yang, J., Wang, L., Du, F., Zhao, J., & Fang, R. (2019) · Parasites & Vectors · doi:10.1186/s13071-019-3297-y · Cited by 29
Metadata
- Authors
- Lucas, K., & Raikhel, A. S.
- Venue
- Insect Biochemistry and Molecular Biology
- Publisher
- Elsevier BV
- Published
- 2013-01
- Volume
- 43
- Issue
- 1
- Pages
- 24-38
- ISSN
- 0965-1748 (ISSN-L)
- OpenAlex
- W1999309921
- Cited by
- 207
- References
- 19
- FWCI
- 2.64
- Type
- journal article
- Language
- en
- Open access
- green
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