Evidence and potential in vivo functions for biofluid miRNAs: From expression profiling to functional testing: Potential roles of extracellular miRNAs as indicators of physiological change and as agents of intercellular information exchange

Untitled work

Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714 · see citing works

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

Bustin, S. A., Benes, V., Garson, J. A., Hellemans, J., Huggett, J., Kubista, M., Mueller, R., Nolan, T., Pfaffl, M. W., Shipley, G. L., et al. (2009) · Clinical Chemistry · doi:10.1373/clinchem.2008.112797 · Cited by 16,303 · see citing works

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J. J., & Lötvall, J. O. (2007) · Nature Cell Biology · doi:10.1038/ncb1596 · Cited by 12,834 · see citing works

The functions of animal microRNAs

Ambros, V. (2004) · Nature · doi:10.1038/nature02871 · Cited by 10,728 · see citing works

Most mammalian mRNAs are conserved targets of microRNAs

Friedman, R. C., Farh, K. K.-H., Burge, C. B., & Bartel, D. P. (2009) · Genome Research · doi:10.1101/gr.082701.108 · Cited by 8,462 · see citing works

Circulating microRNAs as stable blood-based markers for cancer detection

Mitchell, P. S., Parkin, R. K., Kroh, E. M., Fritz, B. R., Wyman, S. K., Pogosova-Agadjanyan, E. L., Peterson, A., Noteboom, J., O'Briant, K. C., Allen, A., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804549105 · Cited by 7,969 · see citing works

Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids

Théry, C., Amigorena, S., Raposo, G., & Clayton, A. (2006) · Current Protocols in Cell Biology · doi:10.1002/0471143030.cb0322s30 · Cited by 5,766 · see citing works

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Skog, J., Würdinger, T., van Rijn, S., Meijer, D. H., Gainche, L., Curry, W. T., Carter, B. S., Krichevsky, A. M., & Breakefield, X. O. (2008) · Nature Cell Biology · doi:10.1038/ncb1800 · Cited by 5,001 · see citing works

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

Chen, X., Ba, Y., Ma, L., Cai, X., Yin, Y., Wang, K., Guo, J., Zhang, Y., Chen, J., Guo, X., et al. (2008) · Cell Research · doi:10.1038/cr.2008.282 · Cited by 4,560 · see citing works

Membrane vesicles as conveyors of immune responses

Théry, C., Ostrowski, M., & Segura, É. (2009) · Nature reviews. Immunology · doi:10.1038/nri2567 · Cited by 3,869 · see citing works

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

Trajković, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B., & Simons, M. (2008) · Science · doi:10.1126/science.1153124 · Cited by 3,639 · see citing works

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

Arroyo, J. D., Chevillet, J. R., Kroh, E. M., Ruf, I. K., Pritchard, C. C., Gibson, D. F., Mitchell, P. S., Bennett, C. F., Pogosova-Agadjanyan, E. L., Stirewalt, D. L., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019055108 · Cited by 3,294 · see citing works

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

Vickers, K. C., Palmisano, B. T., Shoucri, B. M., Shamburek, R. D., & Remaley, A. T. (2011) · Nature Cell Biology · doi:10.1038/ncb2210 · Cited by 2,741 · see citing works

Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: Selective externalization of the receptor

Pan, B., & Johnstone, R. M. (1983) · Cell · doi:10.1016/0092-8674(83)90040-5 · Cited by 2,042 · see citing works

Characterization of extracellular circulating microRNA

Turchinovich, A., Weiz, L., Langheinz, A., & Burwinkel, B. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkr254 · Cited by 1,941 · see citing works

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

Kosaka, N., Iguchi, H., Yoshioka, Y., Takeshita, F., Matsuki, Y., & Ochiya, T. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.107821 · Cited by 1,934 · see citing works

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

Villarroya-Beltri, C., Gutiérrez-Vázquez, C., Sánchez-Cabo, F., Perez-Hernandez, D., Vázquez, J., Martín-Cófreces, N., Martínez-Herrera, D. J., Pascual-Montano, A., Mittelbrunn, M., & Sánchez-Madrid, F. (2013) · Nature Communications · doi:10.1038/ncomms3980 · Cited by 1,907 · see citing works

Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

Mittelbrunn, M., Gutiérrez‐Vázquez, C., Villarroya‐Beltri, C., González, S., Sánchez‐Cabo, F., González, M. A., Bernad, A., & Sánchez‐Madrid, F. (2011) · Nature Communications · doi:10.1038/ncomms1285 · Cited by 1,768 · see citing works

Detection of elevated levels of tumour‐associated microRNAs in serum of patients with diffuse large B‐cell lymphoma

Lawrie, C. H., Gal, S., Dunlop, H. M., Pushkaran, B., Liggins, A. P., Pulford, K. A. F., Banham, A. H., Pezzella, F., Boultwood, J., Wainscoat, J. S., et al. (2008) · British Journal of Haematology · doi:10.1111/j.1365-2141.2008.07077.x · Cited by 1,739 · see citing works

Functional delivery of viral miRNAs via exosomes

Pegtel, D. M., Cosmopoulos, K., Thorley‐Lawson, D. A., van Eijndhoven, M. A. J., Hopmans, E. S., Lindenberg, J. L., de Gruijl, T. D., Wurdinger, T. D., & Middeldorp, J. M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914843107 · Cited by 1,648 · see citing works

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

Fabbri, M., Paone, A., Calore, F., Galli, R., Gaudio, E., Santhanam, R., Lovat, F., Fadda, P., Mao, C., Nuovo, G. J., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209414109 · Cited by 1,558 · see citing works

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

Hunter, M. P., Ismail, N., Zhang, X., Aguda, B. D., Lee, E. J., Yu, L., Xiao, T., Schafer, J., Lee, M. T., Schmittgen, T. D., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003694 · Cited by 1,453 · see citing works

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

Kalra, H., Simpson, R. J., Ji, H., Aikawa, E., Altevogt, P., Askenase, P., Bond, V. C., Borràs, F. E., Breakefield, X., Budnik, V., et al. (2012) · PLoS Biology · doi:10.1371/journal.pbio.1001450 · Cited by 1,367 · see citing works

Small non-coding RNAs in animal development

Stefani, G., & Slack, F. J. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2347 · Cited by 1,361 · see citing works

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes.

Montecalvo, A., Larregina, A. T., Shufesky, W. J., Beer Stolz, D., Sullivan, M. L. G., Karlsson, J. M., Baty, C. J., Gibson, G. A., Erdos, G., Wang, Z., et al. (2012) · Blood · doi:10.1182/blood-2011-02-338004 · Cited by 1,262 · see citing works

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

Zhang, Y., Liu, D., Chen, X., Li, J., Li, L., Bian, Z., Sun, F., Lu, J., Yin, Y., Cai, X. F., et al. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.06.010 · Cited by 1,190 · see citing works

Circulating microRNAs, potential biomarkers for drug-induced liver injury

Wang, K., Zhang, S., Marzolf, B., Troisch, P., Brightman, A., Hu, Z., Hood, L. E., & Galas, D. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813371106 · Cited by 1,149 · see citing works

Quantitative and stoichiometric analysis of the microRNA content of exosomes

Chevillet, J. R., Kang, Q., Ruf, I. K., Briggs, H., Vojtech, L. N., Hughes, S. M., Cheng, H. H., Arroyo, J. D., Meredith, E. K., Gallichotte, E. N., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1408301111 · Cited by 1,105 · see citing works

The majority of microRNAs detectable in serum and saliva is concentrated in exosomes

Gallo, A., Tandon, M., Alevizos, I., & Illei, G. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030679 · Cited by 1,060 · see citing works

Active Wnt proteins are secreted on exosomes

Gross, J. C., Chaudhary, V., Bartscherer, K., & Boutros, M. (2012) · Nature Cell Biology · doi:10.1038/ncb2574 · Cited by 1,025 · see citing works

Export of microRNAs and microRNA-protective protein by mammalian cells

Wang, K., Zhang, S., Weber, J., Baxter, D., & Galas, D. J. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq601 · Cited by 1,002 · see citing works

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

Gibbings, D., Ciaudo, C., Erhardt, M., & Voinnet, O. (2009) · Nature Cell Biology · doi:10.1038/ncb1929 · Cited by 990 · see citing works

A novel and universal method for microRNA RT-qPCR data normalization

Mestdagh, P., Van Vlierberghe, P., De Weer, A., Muth, D., Westermann, F., Speleman, F., & Vandesompele, J. (2009) · Genome Biology · doi:10.1186/gb-2009-10-6-r64 · Cited by 924 · see citing works

Blood Cell Origin of Circulating MicroRNAs: A Cautionary Note for Cancer Biomarker Studies

Pritchard, C. C., Kroh, E., Wood, B., Arroyo, J. D., Dougherty, K. J., Miyaji, M. M., Tait, J. F., & Tewari, M. (2012) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-11-0370 · Cited by 879 · see citing works

As we wait: coping with an imperfect nomenclature for extracellular vesicles

Gould, S. J., & Raposo, G. (2013) · Journal of Extracellular Vesicles · doi:10.3402/jev.v2i0.20389 · Cited by 864 · see citing works

Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche

Grange, C., Tapparo, M., Collino, F., Vitillo, L., Damasco, C., Deregibus, M. C., Tetta, C., Bussolati, B., & Camussi, G. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-0241 · Cited by 848 · see citing works

Salivary microRNA: Discovery, Characterization, and Clinical Utility for Oral Cancer Detection

Park, N. J., Zhou, H., Elashoff, D. A., Henson, B. S., Kastratović, D. A., Abemayor, E., & Wong, D. T. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-0736 · Cited by 845 · see citing works

Detection and Characterization of Placental MicroRNAs in Maternal Plasma

Chim, S. S. C., Shing, T. K. F., Hung, E. C. W., Leung, T.-Y., Lau, T. K., Chiu, R. W. K., & Lo, Y. M. D. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.097972 · Cited by 844 · see citing works

Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell‐free blood

Cheng, L., Sharples, R. A., Scicluna, B. J., & Hill, A. F. (2014) · Journal of Extracellular Vesicles · doi:10.3402/jev.v3.23743 · Cited by 840 · see citing works

Exosome uptake through clathrin-mediated endocytosis and macropinocytosis and mediating miR-21 delivery

Tian, T., Zhu, Y.-L., Zhou, Y.-Y., Liang, G.-F., Wang, Y.-Y., Hu, F.-H., & Xiao, Z.-D. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.588046 · Cited by 726 · see citing works

Analysis of Circulating MicroRNA: Preanalytical and Analytical Challenges

McDonald, J. S., Milosevic, D., Reddi, H. V., Grebe, S. K., & Algeciras‐Schimnich, A. (2011) · Clinical Chemistry · doi:10.1373/clinchem.2010.157198 · Cited by 684 · see citing works

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs

Chen, T. S., Lai, R. C., Lee, M. M., Choo, A. B. H., Lee, C. N., & Lim, S. K. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp857 · Cited by 660 · see citing works

Microvesicles Derived from Adult Human Bone Marrow and Tissue Specific Mesenchymal Stem Cells Shuttle Selected Pattern of miRNAs

Collino, F., Deregibus, M. C., Bruno, S., Sterpone, L., Aghemo, G., Viltono, L., Tetta, C., & Camussi, G. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011803 · Cited by 608 · see citing works

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

Okoye, I., Coomes, S. M., Pelly, V. S., Czieso, S., Papayannopoulos, V., Tolmachova, T., Seabra, M. C., & Wilson, M. S. (2014) · Immunity · doi:10.1016/j.immuni.2014.05.019 · Cited by 604 · see citing works

Nontemplated Nucleotide Additions Distinguish the Small RNA Composition in Cells from Exosomes

Koppers‐Lalic, D., Hackenberg, M., Bijnsdorp, I. V., van Eijndhoven, M. A. J., Sadek, P., Sie, D., Zini, N., Middeldorp, J. M., Ylstra, B., de Menezes, R. X., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.08.027 · Cited by 589 · see citing works

Current methods for the isolation of extracellular vesicles

Momen-Heravi, F., Balaj, L., Alian, S., Mantel, P., Halleck, A., Trachtenberg, A., Soria, C. E., Oquin, S., Bonebreak, C. M., Saraçoğlu, E., et al. (2013) · Biological chemistry · doi:10.1515/hsz-2013-0141 · Cited by 568 · see citing works

Intercellular nanovesicle-mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth

Kogure, T., Lin, W.-L., Yan, I. K., Braconi, C., & Patel, T. (2011) · Hepatology · doi:10.1002/hep.24504 · Cited by 551 · see citing works

Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of resident renal cells

Cantaluppi, V., Gatti, S., Medica, D., Figliolini, F., Bruno, S., Deregibus, M. C., Sordi, A., Biancone, L., Tetta, C., & Camussi, G. (2012) · Kidney International · doi:10.1038/ki.2012.105 · Cited by 535 · see citing works

Isolation of biologically-active exosomes from human plasma

Müller, L., Hong, C., Stolz, D. B., Watkins, S. C., & Whiteside, T. L. (2014) · Journal of Immunological Methods · doi:10.1016/j.jim.2014.06.007 · Cited by 490 · see citing works

Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway

Zhuang, G., Wu, X., Jiang, Z., Kasman, I. M., Yao, J. J., Guan, Y., Oeh, J., Modrusan, Z. D., Bais, C., Sampath, D., et al. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.183 · Cited by 472 · see citing works

Dynamic regulation of miRNA expression in ordered stages of cellular developmentPreprint

Neilson, J. R., Zheng, G. X. Y., Burge, C. B., & Sharp, P. A. (2007) · Genes & Development · doi:10.1101/gad.1522907 · Cited by 471 · see citing works

Methodological challenges in utilizing mi<scp>RNA</scp>s as circulating biomarkers

Moldovan, L., Batte, K. E., Trgovcich, J., Wisler, J., Marsh, C. B., & Piper, M. (2014) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12236 · Cited by 436 · see citing works

HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cells

Tabet, F., Vickers, K. C., Cuesta Torres, L. F., Wiese, C. B., Shoucri, B. M., Lambert, G., Catherinet, C., Prado-Lourenco, L., Levin, M. G., Thacker, S., et al. (2014) · Nature Communications · doi:10.1038/ncomms4292 · Cited by 428 · see citing works

Exosomes from Drug-Resistant Breast Cancer Cells Transmit Chemoresistance by a Horizontal Transfer of MicroRNAs

Chen, W.-X., Liu, X.-M., Lv, M., Chen, L., Zhao, J.-H., Zhong, S., Ji, M., Hu, Q., Luo, Z., Wu, J.-Z., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095240 · Cited by 413 · see citing works

High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries

Mullokandov, G., Baccarini, A., Ruzo, A., Jayaprakash, A. D., Tung, N., Israelow, B., Evans, M. J., Sachidanandam, R., & Brown, B. D. (2012) · Nature Methods · doi:10.1038/nmeth.2078 · Cited by 394 · see citing works

Neuronal Exosomal miRNA-dependent Translational Regulation of Astroglial Glutamate Transporter GLT1

Morel, L., Regan, M., Higashimori, H., Ng, S. K., Esau, C., Vidensky, S., Rothstein, J., & Yang, Y. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.410944 · Cited by 390 · see citing works

Physical exercise induces rapid release of small extracellular vesicles into the circulation

Frühbeis, C., Helmig, S., Tug, S., Simon, P., & Krämer‐Albers, E. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.28239 · Cited by 360 · see citing works

Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells

Wei, Y., Lai, X., Yu, S., Chen, S., Ma, Y., Zhang, Y., Li, H., Zhu, X., Yao, L., & Zhang, J. (2014) · Breast Cancer Research and Treatment · doi:10.1007/s10549-014-3037-0 · Cited by 355 · see citing works

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

Landthaler, M., Gaidatzis, D., Rothballer, A., Chen, P., Soll, S. J., Dinic, L., Ojo, T., Hafner, M., Zavolan, M., & Tuschl, T. (2008) · RNA · doi:10.1261/rna.1351608 · Cited by 355 · see citing works

Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS

Momen‐Heravi, F., Bala, S., Kodys, K., & Szabó, G. (2015) · Scientific Reports · doi:10.1038/srep09991 · Cited by 348 · see citing works

Small Peptides Switch the Transcriptional Activity of Shavenbaby During Drosophila Embryogenesis

Kondo, T., Plaza, S., Zanet, J., Benrabah, E., Valenti, P., Hashimoto, Y., Kobayashi, S., Payre, F., & Kageyama, Y. (2010) · Science · doi:10.1126/science.1188158 · Cited by 348 · see citing works

Age-related changes in microRNA levels in serum

Hooten, N. N., Fitzpatrick, M., Wood, W. H., De, S., Ejiogu, N., Zhang, Y., Mattison, J. A., Becker, K. G., Zonderman, A. B., & Evans, M. K. (2013) · Aging · doi:10.18632/aging.100603 · Cited by 329 · see citing works

Comparison of serum exosome isolation methods for microRNA profiling

Rekker, K., Saare, M., Roost, A. M., Kubo, A., Zarovni, N., Chiesi, A., Salumets, A., & Peters, M. (2013) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2013.10.020 · Cited by 327 · see citing works

Characterization of Levels and Cellular Transfer of Circulating Lipoprotein-Bound MicroRNAs

Wagner, J., Riwanto, M., Besler, C., Knau, A., Fichtlscherer, S., Roexe, T., Zeiher, A. M., Landmesser, U., & Dimmeler, S. (2013) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.300741 · Cited by 323 · see citing works

Extracellular MicroRNAs Activate Nociceptor Neurons to Elicit Pain via TLR7 and TRPA1

Park, C., Xu, Z., Berta, T., Han, Q., Chen, G., Liu, X., & Ji, R. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.011 · Cited by 316 · see citing works

Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages

Momen‐Heravi, F., Bala, S., Bukong, T. N., & Szabó, G. (2014) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2014.03.014 · Cited by 306 · see citing works

Zcchc11-dependent uridylation of microRNA directs cytokine expression

Jones, M. R., Quinton, L. J., Blahna, M. T., Neilson, J. R., Fu, S., Ivanov, A. R., Wolf, D. A., & Mizgerd, J. P. (2009) · Nature Cell Biology · doi:10.1038/ncb1931 · Cited by 295 · see citing works

Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting

van Balkom, B. W. M., Eisele, A. S., Pegtel, D. M., Bervoets, S., & Verhaar, M. C. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.26760 · Cited by 294 · see citing works

Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons

Goldie, B. J., Dun, M. D., Lin, M., Smith, N. D., Verrills, N. M., Dayas, C. V., & Cairns, M. J. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku594 · Cited by 294 · see citing works

Circulating micro‐RNA expression profiles in early stage nonsmall cell lung cancer

Heegaard, N. H. H., Schetter, A. J., Welsh, J. A., Yoneda, M., Bowman, E. D., & Harris, C. C. (2011) · International Journal of Cancer · doi:10.1002/ijc.26153 · Cited by 289 · see citing works

Human Traumatic Brain Injury Alters Plasma microRNA Levels

Redell, J. B., Moore, A. N., Ward, N. H., Hergenroeder, G. W., & Dash, P. K. (2010) · Journal of Neurotrauma · doi:10.1089/neu.2010.1481 · Cited by 282 · see citing works

Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression

Gidlöf, O., van der Brug, M., Öhman, J. N., Gilje, P., Olde, B., Wahlestedt, C., & Erlinge, D. (2013) · Blood · doi:10.1182/blood-2012-10-461798 · Cited by 273 · see citing works

MicroRNAs transfer from human macrophages to hepato-carcinoma cells and inhibit proliferation

Aucher, A., Rudnicka, D., & Davis, D. M. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1301728 · Cited by 247 · see citing works

Kinetic Analysis Reveals the Fate of a MicroRNA following Target Regulation in Mammalian Cells

Baccarini, A., Chauhan, H., Gardner, T. J., Jayaprakash, A. D., Sachidanandam, R., & Brown, B. D. (2011) · Current Biology · doi:10.1016/j.cub.2011.01.067 · Cited by 235 · see citing works

Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1

Bronisz, A., Wang, Y., Nowicki, M. O., Peruzzi, P., Ansari, K. I., Ogawa, D., Balaj, L., Rienzo, G. D., Mineo, M., Nakano, I., et al. (2013) · Cancer Research · doi:10.1158/0008-5472.can-13-2650 · Cited by 234 · see citing works

Assessment of small RNA sorting into different extracellular fractions revealed by high-throughput sequencing of breast cell lines

Tosar, J. P., Gámbaro, F., Sanguinetti, J., Bonilla, B., Witwer, K. W., & Cayota, A. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv432 · Cited by 228 · see citing works

Argonaute 2 Complexes Selectively Protect the Circulating MicroRNAs in Cell-Secreted Microvesicles

Li, L., Zhu, D., Huang, L., Zhang, J., Bian, Z., Chen, X., Liu, Y., Zhang, C., & Zen, K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046957 · Cited by 216 · see citing works

Insect MicroRNAs: Biogenesis, expression profiling and biological functions

Lucas, K. J., & Raikhel, A. S. (2012) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2012.10.009 · Cited by 203 · see citing works

Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells

Ekström, K., Valadi, H., Sjöstrand, M., Malmhäll, C., Bossios, A., Eldh, M., & Lötvall, J. (2012) · Journal of Extracellular Vesicles · doi:10.3402/jev.v1i0.18389 · Cited by 201 · see citing works

Human Liver Stem Cell-Derived Microvesicles Inhibit Hepatoma Growth in SCID Mice by Delivering Antitumor MicroRNAs

Fonsato, V., Collino, F., Sanchez, M. B. H., Cavallari, C., Deregibus, M. C., Cisterna, B., Bruno, S., Romagnoli, R., Salizzoni, M., Tetta, C., et al. (2012) · Stem Cells · doi:10.1002/stem.1161 · Cited by 200 · see citing works

Modulated microRNA expression during adult lifespan in Caenorhabditis elegans

Ibáñez‐Ventoso, C., Yang, M., Guo, S., Robins, H. S., Padgett, R. W., & Driscoll, M. (2006) · Aging Cell · doi:10.1111/j.1474-9726.2006.00210.x · Cited by 193 · see citing works

Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing

Burgos, K., Javaherian, A., Bomprezzi, R., Ghaffari, L., Rhodes, S. N., Courtright-Lim, A., Tembe, W., Kim, S., Metpally, R. P. R., & Keuren‐Jensen, K. R. V. (2013) · RNA · doi:10.1261/rna.036863.112 · Cited by 191 · see citing works

Functional MicroRNA Is Transferred between Glioma Cells

Katakowski, M., Buller, B., Wang, X., Rogers, T., & Chopp, M. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-0604 · Cited by 186 · see citing works

The P4-ATPase TAT-5 Inhibits the Budding of Extracellular Vesicles in C. elegans Embryos

Wehman, A. M., Poggioli, C., Schweinsberg, P. J., Grant, B. D., & Nance, J. (2011) · Current Biology · doi:10.1016/j.cub.2011.10.040 · Cited by 185 · see citing works

Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis

Müller, G. A., Schneider, M., Biemer‐Daub, G., & Wied, S. (2011) · Cellular Signalling · doi:10.1016/j.cellsig.2011.03.013 · Cited by 176 · see citing works

Proteomic Analysis of C2C12 Myoblast and Myotube Exosome-Like Vesicles: A New Paradigm for Myoblast-Myotube Cross Talk?

Forterre, A. V., Jalabert, A., Berger, E., Baudet, M., Chikh, K., Errazuriz-Cerda, E., Larichaudy, J. D., Chanon, S., Weiss‐Gayet, M., Hesse, A.-M., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0084153 · Cited by 176 · see citing works

Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation

Ogawa, R., Tanaka, C., Sato, M., Nagasaki, H., Sugimura, K., Okumura, K., Nakagawa, Y., & Aoki, N. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.07.008 · Cited by 175 · see citing works

miRNA cargo within exosome‐like vesicle transfer influences metastatic bone colonization

Valencia, K., Luis-Ravelo, D., Bovy, N., Antón, I., Martínez-Canarias, S., Zandueta, C., Ormazabal, C., Struman, I., Tabruyn, S. P., Rebmann, V., et al. (2014) · Molecular Oncology · doi:10.1016/j.molonc.2014.01.012 · Cited by 166 · see citing works

Impact of serum storage conditions on microRNA stability

Grasedieck, S., Schöler, N., Bommer, M., Niess, J. H., Tumani, H., ROUHI, A. M., Bloehdorn, J., Liebisch, P., Mertens, D., Döhner, H., et al. (2012) · Leukemia · doi:10.1038/leu.2012.106 · Cited by 165 · see citing works

Developmental Endothelial Locus-1 (Del-1) Mediates Clearance of Platelet Microparticles by the Endothelium

Dasgupta, S. K., Le, A., Chavakis, T., Rumbaut, R. E., & Thiagarajan, P. (2012) · Circulation · doi:10.1161/circulationaha.111.068833 · Cited by 158 · see citing works

BMP-regulated exosomes from <i>Drosophila</i> male reproductive glands reprogram female behavior

Corrigan, L., Redhai, S., Leiblich, A., Fan, S.-J., Perera, S. M. W., Patel, R., Gandy, C., Wainwright, S. M., Morris, J. F., Hamdy, F., et al. (2014) · Journal of Cell Biology · doi:10.1083/jcb.201401072 · Cited by 155 · see citing works

Exosomal shuttling of miR-126 in endothelial cells modulates adhesive and migratory abilities of chronic myelogenous leukemia cells

Taverna, S., Amodeo, V., Saieva, L., Russo, A. D., Giallombardo, M., Leo, G. D., & Alessandro, R. (2014) · Molecular Cancer · doi:10.1186/1476-4598-13-169 · Cited by 150 · see citing works

Comparison of Methods for miRNA Extraction from Plasma and Quantitative Recovery of RNA from Cerebrospinal Fluid

McAlexander, M. A., Phillips, M. J., & Witwer, K. W. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00083 · Cited by 148 · see citing works

Biodistribution and function of extracellular miRNA-155 in mice

Bala, S., Csák, T., Momen‐Heravi, F., Lippai, D., Kodys, K., Catalano, D., Satishchandran, A., Ambros, V., & Szabó, G. (2015) · Scientific Reports · doi:10.1038/srep10721 · Cited by 141 · see citing works

MicroRNAs—novel regulators of systemic lupus erythematosus pathogenesis

Shen, N., Liang, D., Tang, Y., de Vries, N., & Tak, P. P. (2012) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2012.142 · Cited by 137 · see citing works

Endothelial Microparticle Uptake in Target Cells Is Annexin I/Phosphatidylserine Receptor Dependent and Prevents Apoptosis

Jansen, F., Yang, X., Hoyer, F. F., Paul, K., Heiermann, N., Becher, M. U., Hussein, N. S. A., Kebschull, M., Bedorf, J., Franklin, B. S., et al. (2012) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.112.253229 · Cited by 134 · see citing works

A Critical Evaluation of microRNA Biomarkers in Non-Neoplastic Disease

Haider, B. A., Baras, A. S., McCall, M. N., Hertel, J. A., Cornish, T. C., & Halushka, M. K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089565 · Cited by 133 · see citing works

Cell contact-dependent acquisition of cellular and viral nonautonomously encoded small RNAs.Preprint

Rechavi, O., Erlich, Y., Amram, H., Flomenblit, L., Karginov, F. V., Goldstein, I., Hannon, G., & Kloog, Y. (2009) · Genes & Development · doi:10.1101/gad.1789609 · Cited by 132 · see citing works

Dampening Enthusiasm for Circulating MicroRNA in Breast Cancer

Leidner, R. S., Li, L., & Thompson, C. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057841 · Cited by 113 · see citing works

Amedeo Avogadro's cry: What is 1 µg of exosomes?

Sverdlov, E. D. (2012) · BioEssays · doi:10.1002/bies.201200045 · Cited by 110 · see citing works

Circulating MicroRNAs as Biomarkers for Inflammatory Diseases

Mi, S., Zhang, J., Zhang, W., & Huang, R. S. (2013) · MicroRNA · doi:10.2174/2211536611302010007 · Cited by 106 · see citing works

Identification of tubular injury microRNA biomarkers in urine: comparison of next-generation sequencing and qPCR-based profiling platforms

Nassirpour, R., Mathur, S., Gosink, M. M., Li, Y., Shoieb, A. M., Wood, J., O’Neil, S. P., Homer, B. L., & Whiteley, L. O. (2014) · BMC Genomics · doi:10.1186/1471-2164-15-485 · Cited by 83 · see citing works

MicroRNAs in Sjögren's syndrome as a prototypic autoimmune disease

Alevizos, I., & Illei, G. G. (2010) · Autoimmunity Reviews · doi:10.1016/j.autrev.2010.05.009 · Cited by 80 · see citing works

Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium

Laurent, L. C., Abdel‐Mageed, A. B., Adelson, P. D., Arango, J. I., Balaj, L., Breakefield, X. O., Carlson, E. W. J., Carter, B. S., Majem, B., Chen, C. C., et al. (2015) · Journal of Extracellular Vesicles · doi:10.3402/jev.v4.26533 · Cited by 69 · see citing works

Cell-free microRNAs: potential biomarkers in need of standardized reporting

Kirschner, M. B., van Zandwijk, N., & Reid, G. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00056 · Cited by 69 · see citing works

miR-21–Containing Microvesicles from Injured Tubular Epithelial Cells Promote Tubular Phenotype Transition by Targeting PTEN Protein

Zhou, Y., Xiong, M., Fang, L., Jiang, L., Wen, P., Dai, C., Zhang, C., & Yang, J. (2013) · American Journal Of Pathology · doi:10.1016/j.ajpath.2013.06.032 · Cited by 68 · see citing works

In Vivo Imaging of Functional Targeting of miR-221 in Papillary Thyroid Carcinoma

Kim, H. J., Kim, Y., Lee, D. S., Chung, J., & Kim, S. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.108.052894 · Cited by 66 · see citing works

Synaptosomes secrete and uptake functionally active micro<scp>RNA</scp>s via exocytosis and endocytosis pathways

Xu, J., Chen, Q., Zen, K., Zhang, C., & Zhang, Q. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12057 · Cited by 61 · see citing works

Plasma MicroRNAs as Novel Biomarkers for Patients with Intraductal Papillary Mucinous Neoplasms of the Pancreas

Permuth‐Wey, J., Chen, D., Fulp, W. J., Yoder, S., Zhang, Y., Georgeades, C., Husain, K. M., Centeno, B. A., Magliocco, A. M., Coppola, D., et al. (2015) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-15-0094 · Cited by 53 · see citing works

miR-19, miR-345, miR-519c-5p Serum Levels Predict Adverse Pathology in Prostate Cancer Patients Eligible for Active Surveillance

Wang, S., Shiboski, S. C., Belair, C. D., Cooperberg, M. R., Simko, J. P., Stöppler, H., Cowan, J. E., Carroll, P. R., & Blelloch, R. H. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098597 · Cited by 50 · see citing works

Argonaute 2 in Cell-Secreted Microvesicles Guides the Function of Secreted miRNAs in Recipient Cells

Lv, Z., Yao, W., Wang, D., Zhang, C., Zen, K., & Li, L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103599 · Cited by 44 · see citing works

Retro-Orbital Blood Acquisition Facilitates Circulating microRNA Measurement in Zebrafish with Paracetamol Hepatotoxicity

Vliegenthart, A. D. B., Lewis, P. J. S., Tucker, C. S., del Pozo, J., Rider, S., Antoine, D. J., Dubost, V., Westphal, M., Moulin, P., Bailey, M. A., et al. (2014) · Zebrafish · doi:10.1089/zeb.2013.0912 · Cited by 39 · see citing works

Coronary heart disease alters intercellular communication by modifying microparticle‐mediated microRNA transport

Finn, N. A., Eapen, D. J., Manocha, P., Kassem, H. A., Lassegue, B. P., Ghasemzadeh, N., Quyyumi, A. A., & Searles, C. D. (2013) · FEBS Letters · doi:10.1016/j.febslet.2013.08.034 · Cited by 39 · see citing works

Molecular Imaging Strategies for In Vivo Tracking of MicroRNAs: A Comprehensive Review

Hernandez, R., Orbay, H., & Cai, W. (2013) · Current Medicinal Chemistry · doi:10.2174/0929867311320290005 · Cited by 38 · see citing works

Argonaute‐2 Promotes miR‐18a Entry in Human Brain Endothelial Cells

Ferreira, R., Santos, T., Amar, A. P., Gong, A., Chen, T. C., Tahara, S. M., Giannotta, S. L., & Hofman, F. M. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.000968 · Cited by 35 · see citing works

MicroRNA network changes in the brain stem underlie the development of hypertension

DeCicco, D., Zhu, H., Brureau, A., Schwaber, J. S., & Vadigepalli, R. (2015) · Physiological Genomics · doi:10.1152/physiolgenomics.00047.2015 · Cited by 27 · see citing works

Identification and characterization of novel serum microRNA candidates from deep sequencing in cervical cancer patients

Li, J., Tong, H., Zhang, P., Guo, G., Wang, Z., Wen, X., Dong, Z., & Tian, Y. (2014) · Scientific Reports · doi:10.1038/srep06277 · Cited by 26 · see citing works

Circulating microRNAs in Neurodegenerative Diseases

Grasso, M., Piscopo, P., Crestini, A., Confaloni, A., & Denti, M. A. (2015) · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions · doi:10.1007/978-3-0348-0955-9_7 · Cited by 26 · see citing works

Discerning Different In vivo Roles of MicroRNAs by Experimental Approaches in Zebrafish

Pase, L. B., & Lieschke, G. J. (2011) · Methods in cell biology · doi:10.1016/b978-0-12-374814-0.00020-3 · Cited by 5 · see citing works

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

O'Brien, J., Hayder, H., Zayed, Y., & Peng, C. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00402 · Cited by 5,287 · see citing works

RNA in extracellular vesicles

Kim, K. M., Abdelmohsen, K., Mustapić, M., Kapogiannis, D., & Gorospe, M. (2017) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1413 · Cited by 456 · see citing works

Molecular mechanisms of Dicer: endonuclease and enzymatic activity

Song, M.-S., & Rossi, J. J. (2017) · Biochemical Journal · doi:10.1042/bcj20160759 · Cited by 281 · see citing works

Noncoding RNAs in Extracellular Fluids as Cancer Biomarkers: The New Frontier of Liquid Biopsies

Pardini, B., Sabo, A. A., Birolo, G., & Calin, G. A. (2019) · Cancers · doi:10.3390/cancers11081170 · Cited by 198 · see citing works

Human Circulating miRNAs Real-time qRT-PCR-based Analysis: An Overview of Endogenous Reference Genes Used for Data Normalization

Donati, S., Ciuffi, S., & Brandi, M. L. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20184353 · Cited by 139 · see citing works

The translational potential of microRNAs as biofluid markers of urological tumours

Fendler, A., Stephan, C., Yousef, G. M., Kristiansen, G., & Jung, K. (2016) · Nature Reviews Urology · doi:10.1038/nrurol.2016.193 · Cited by 133 · see citing works

Extracellular Vesicle MicroRNA Transfer in Lung Diseases

Chen, J., Hu, C., & Pan, P. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.01028 · Cited by 119 · see citing works

miRNAs as Influencers of Cell–Cell Communication in Tumor Microenvironment

Conti, I., Varano, G., Simioni, C., Laface, I., Milani, D., Rimondi, E., & Neri, L. M. (2020) · Cells · doi:10.3390/cells9010220 · Cited by 91 · see citing works

Circulating Liquid Biopsy Biomarkers in Glioblastoma: Advances and Challenges

Seyhan, A. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147974 · Cited by 85 · see citing works

Understanding the Role of Non-Coding RNAs in Bladder Cancer: From Dark Matter to Valuable Therapeutic Targets

Bica, C., Gulei, D., Cojocneanu, R., Braicu, C., Petruţ, B., & Berindan‐Neagoe, I. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18071514 · Cited by 70 · see citing works

Non-Coding RNAs in Preeclampsia—Molecular Mechanisms and Diagnostic Potential

Munjas, J., Sopić, M., Stefanović, A., Košir, R., Ninić, A., Joksić, I., Antonić, T., Spasojević‐Kalimanovska, V., & Zmrzljak, U. P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910652 · Cited by 63 · see citing works

Circulating miRNAs in bone health and disease

Grillari, J., Mäkitie, R. E., Kocijan, R., Haschka, J., Vázquez, D. C., Semmelrock, E., & Hackl, M. (2020) · Bone · doi:10.1016/j.bone.2020.115787 · Cited by 61 · see citing works

Circulating microRNAs as Potential Biomarkers in Pancreatic Cancer—Advances and Challenges

Seyhan, A. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713340 · Cited by 60 · see citing works

Non-Coding microRNAs as Novel Potential Tumor Markers in Testicular Cancer

Regouc, M., Belge, G., Lorch, A., Dieckmann, K., & Pichler, M. (2020) · Cancers · doi:10.3390/cancers12030749 · Cited by 58 · see citing works

Dysregulated CD4+ T Cells and microRNAs in Myocarditis

Wang, J., & Han, B. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00539 · Cited by 53 · see citing works

A new approach for COVID-19 treatment by micro-RNA

El‐Nabi, S. H., Elhiti, M., & El-Sheekh, M. M. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.110203 · Cited by 55 · see citing works

MicroRNAs in biofluids are novel tools for bladder cancer screening

Liu, X., Liu, X., Wu, Y., Wu, Q., Wang, Q., Yang, Z., & Li, L. (2017) · Oncotarget · doi:10.18632/oncotarget.16026 · Cited by 47 · see citing works

The power of microRNAs as diagnostic and prognostic biomarkers in liquid biopsies

Quirico, L., & Orso, F. (2020) · Cancer Drug Resistance · doi:10.20517/cdr.2019.103 · Cited by 46 · see citing works

Advances in Liquid Biopsy Technology and Implications for Pancreatic Cancer

Raufi, A. G., May, M. S., Hadfield, M. J., Seyhan, A. A., & El‐Deiry, W. S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24044238 · Cited by 45 · see citing works

miRNA interplay: Mechanisms and therapeutic interventions in cancer

Wang, Z., Wang, H., Zhou, S., Mao, J., Zhan, Z., & Duan, S. (2024) · MedComm – Oncology · doi:10.1002/mog2.93 · Cited by 45 · see citing works

Potential of activated microglia as a source of dysregulated extracellular microRNAs contributing to neurodegeneration in amyotrophic lateral sclerosis

Christoforidou, E., Joilin, G., & Hafezparast, M. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01822-4 · Cited by 41 · see citing works

Extracellular Vesicles and MicroRNA: Putative Role in Diagnosis and Treatment of Diabetic Retinopathy

Martins, B. D., Amorim, M., Reis, F., Ambrósio, A. F., & Fernandes, R. (2020) · Antioxidants · doi:10.3390/antiox9080705 · Cited by 42 · see citing works

MicroRNAs from saliva of anopheline mosquitoes mimic human endogenous miRNAs and may contribute to vector-host-pathogen interactions

Arcà, B., Colantoni, A., Fiorillo, C., Severini, F., Beneš, V., Luca, M. D., Calogero, R., & Lombardo, F. (2019) · Scientific Reports · doi:10.1038/s41598-019-39880-1 · Cited by 40 · see citing works

The Prospect and Challenges to the Flow of Liquid Biopsy in Africa

Temilola, D. O., Wium, M., Coulidiati, T. H., Adeola, H. A., Carbone, G. M., Catapano, C. V., & Zerbini, L. F. (2019) · Cells · doi:10.3390/cells8080862 · Cited by 39 · see citing works

Therapeutically Significant MicroRNAs in Primary and Metastatic Brain Malignancies

Balachandran, A. A., Larcher, L. M., Chen, S., & Veedu, R. N. (2020) · Cancers · doi:10.3390/cancers12092534 · Cited by 41 · see citing works

The effects of chronic cadmium exposure on Bufo gargarizans larvae: Histopathological impairment, gene expression alteration and fatty acid metabolism disorder in the liver

Ju, Z., Ya, J., Li, X., Wang, H., & Zhao, H. (2020) · Aquatic Toxicology · doi:10.1016/j.aquatox.2020.105470 · Cited by 32 · see citing works

The role of microRNAs in ovarian function and the transition toward novel therapeutic strategies in fertility preservation: from bench to future clinical application

Alexandri, C., Daniel, A., Bruylants, G., & Demeestere, I. (2019) · Human Reproduction Update · doi:10.1093/humupd/dmz039 · Cited by 30 · see citing works

Clinical Significance of microRNAs in Hematologic Malignancies and Hematopoietic Stem Cell Transplantation

Ševčíková, A., Fridrichová, I., Nikolaieva, N., Kalinkova, L., Omelka, R., Martiniaková, M., & Čierniková, S. (2023) · Cancers · doi:10.3390/cancers15092658 · Cited by 29 · see citing works

Circulating MiR-1290 as a potential diagnostic and disease monitoring biomarker of human gastrointestinal tumors

Xu, L., Cai, Y., Chen, X., Zhu, Y., & Cai, J. (2021) · BMC Cancer · doi:10.1186/s12885-021-08729-0 · Cited by 27 · see citing works

Epigenetic Biomarkers of Renal Cell Carcinoma for Liquid Biopsy Tests

Kubiliūtė, R., & Jarmalaitė, S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168846 · Cited by 26 · see citing works

miRNAs in the Regulation of Cancer Immune Response: Effect of miRNAs on Cancer Immunotherapy

Pottoo, F. H., Iqubal, A., Iqubal, M. K., Salahuddin, M., Rahman, J. U., Alhajri, N., & Shehadeh, M. (2021) · Cancers · doi:10.3390/cancers13236145 · Cited by 22 · see citing works

Personalized Management of Myocarditis and Inflammatory Cardiomyopathy in Clinical Practice

Tymińska, A., Ozierański, K., Skwarek, A., Kapłon‐Cieślicka, A., Baritussio, A., Grabowski, M., Marcolongo, R., & Caforio, A. L. P. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12020183 · Cited by 25 · see citing works

Could MicroRNAs Be Useful Tools to Improve the Diagnosis and Treatment of Rare Gynecological Cancers? A Brief Overview

Fiore, R. D., Suleiman, S., Pentimalli, F., O’Toole, S. A., O’Leary, J. J., Ward, M. P., Conlon, N. T., Sabol, M., Ozretić, P., Erson-Bensan, A. E., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22083822 · Cited by 22 · see citing works

Uptake and impact of natural diet-derived small RNA in invertebrates: Implications for ecology and agriculture

Chan, S. Y., & Snow, J. W. (2016) · RNA Biology · doi:10.1080/15476286.2016.1248329 · Cited by 21 · see citing works

Dysregulated MicroRNA Expression Profiles and Potential Cellular, Circulating and Polymorphic Biomarkers in Non-Hodgkin Lymphoma

Bradshaw, G., Sutherland, H. G. E., Haupt, L. M., & Griffiths, L. R. (2016) · Genes · doi:10.3390/genes7120130 · Cited by 21 · see citing works

Circulating miRNAs: A New Opportunity in Bone Fragility

Donati, S., Ciuffi, S., Palmini, G., & Brandi, M. L. (2020) · Biomolecules · doi:10.3390/biom10060927 · Cited by 21 · see citing works

MicroRNA exocytosis by large dense-core vesicle fusion

Gümürdü, A., Yildiz, R., Eren, E., Karakülah, G., Ünver, T., Genç, Ş., & Park, Y. (2017) · Scientific Reports · doi:10.1038/srep45661 · Cited by 21 · see citing works

MicroRNAs and other small RNAs in Aedes aegypti saliva and salivary glands following chikungunya virus infection

Fiorillo, C., Yen, P., Colantoni, A., Mariconti, M., de Azevedo, N. T. D., Lombardo, F., Failloux, A., & Arcà, B. (2022) · Scientific Reports · doi:10.1038/s41598-022-13780-3 · Cited by 20 · see citing works

Extracellular RNA: Emerging roles in cancer cell communication and biomarkers

Kim, S., Jeon, O. H., & Jeon, Y.-J. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.09.002 · Cited by 20 · see citing works

Autoimmune Atrophic Gastritis: The Role of miRNA in Relation to Helicobacter Pylori Infection

Zingone, F., Pilotto, V., Cardin, R., Maddalo, G., Orlando, C., Fassan, M., Marsilio, I., Collesei, E., Pelizzaro, F., & Farinati, F. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.930989 · Cited by 17 · see citing works

Multiple Endocrine Neoplasia Type 1: The Potential Role of microRNAs in the Management of the Syndrome

Donati, S., Ciuffi, S., Marini, F., Palmini, G., Miglietta, F., Aurilia, C., & Brandi, M. L. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207592 · Cited by 17 · see citing works

Interplay between host non-coding RNAs and influenza viruses

Bamunuarachchi, G., Pushparaj, S., & Liu, L. (2021) · RNA Biology · doi:10.1080/15476286.2021.1872170 · Cited by 17 · see citing works

Liquid Biopsy for Cancer Cachexia: Focus on Muscle-Derived microRNAs

Belli, R., Ferraro, E., Molfino, A., Carletti, R., Tambaro, F., Costelli, P., & Muscaritoli, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22169007 · Cited by 20 · see citing works

Circulatory microRNAs in helminthiases: Potent as diagnostics biomarker, its potential role and limitations

Ullah, H., Tian, Y., Arbab, S., Li, K., Khan, M. I. U., Rahman, S. U., Qadeer, A., Muhammad, N., Suleman, S., & Hassan, I. U. (2022) · Frontiers in Veterinary Science · doi:10.3389/fvets.2022.1018872 · Cited by 15 · see citing works

Exploring the Role of microRNAs as Blood Biomarkers in Alzheimer’s Disease and Frontotemporal Dementia

Petracci, I., Bellini, S., Goljanek‐Whysall, K., Quinlan, L. R., Fiszer, A., Cakmak, A., Njume, C. M., Borroni, B., & Ghidoni, R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26073399 · Cited by 14 · see citing works

The Role of miRNAs in Drosophila melanogaster Male Courtship Behavior

Iftikhar, H., Johnson, N. L., Marlatt, M. L., & Carney, G. E. (2019) · Genetics · doi:10.1534/genetics.118.301901 · Cited by 14 · see citing works

The Role of MicroRNAs in Uterine Leiomyosarcoma Diagnosis and Treatment

Psilopatis, I., Vrettou, K., Kokkali, S., & Theocharis, S. E. (2023) · Cancers · doi:10.3390/cancers15092420 · Cited by 13 · see citing works

MicroRNA Exocytosis by Vesicle Fusion in Neuroendocrine Cells

Park, Y. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00355 · Cited by 259 · see citing works

Epigenetics of spondyloarthritis

Cherqaoui, B., Crémazy, F. G. E., Hue, C., Garchon, H., Bréban, M., & Costantino, F. (2020) · Joint Bone Spine · doi:10.1016/j.jbspin.2020.06.003 · Cited by 12 · see citing works

miRNA in head and neck squamous cell carcinomas: promising but still distant future of personalized oncology

Kozłowska-Masłoń, J., Guglas, K., Kolenda, T., Lamperska, K. M., & Makałowska, I. (2023) · Reports of Practical Oncology & Radiotherapy · doi:10.5603/rpor.96666 · Cited by 11 · see citing works

From Natriuretic Peptides to microRNAs: Multi-Analyte Liquid Biopsy Horizons in Heart Failure

Charidemou, E., Felekkis, K. N., & Papaneophytou, C. P. (2025) · Biomolecules · doi:10.3390/biom15081189 · Cited by 14 · see citing works

MicroRNAs as Potential Biomarkers in Pituitary Adenomas

Donati, S., Aurilia, C., Palmini, G., Miglietta, F., Falsetti, I., Iantomasi, T., & Brandi, M. L. (2021) · Non-Coding RNA · doi:10.3390/ncrna7030055 · Cited by 11 · see citing works

Potential Anti-Metastatic Role of the Novel miR-CT3 in Tumor Angiogenesis and Osteosarcoma Invasion

Raimondi, L., Gallo, A., Cuscino, N., Luca, A. D., Costa, V., Carina, V., Bellavia, D., Bulati, M., Alessandro, R., Fini, M., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23020705 · Cited by 11 · see citing works

miRNAs: Perspective towards the use for body fluid identification

Praihirunkit, P. (2020) · Siriraj Medical Journal/San Sirirat · doi:10.33192/smj.2020.70 · Cited by 10 · see citing works

MicroRNA: A Potential Diagnosis for Male Infertility

Forouhari, S., Mahmoudi, E., Safdarian, E., Beygi, Z., & Hayat, S. M. G. (2020) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557520999201209213319 · Cited by 10 · see citing works

The Role of MicroRNA in the Myocarditis: a Small Actor for a Great Role

Chimenti, C., Magnocavallo, M., Vetta, G., Alfarano, M., Manguso, G., Ajmone, F., Ballatore, F., Costantino, J., Ciaramella, P., Severino, P., et al. (2023) · Current Cardiology Reports · doi:10.1007/s11886-023-01888-5 · Cited by 10 · see citing works

MicroRNAs as Potential Graft Rejection or Tolerance Biomarkers and Their Dilemma in Clinical Routines Behaving like Devilish, Angelic, or Frightening Elements

Legáz, I., Jiménez-Coll, V., González-López, R., Fernández-González, M., Alegría-Marcos, M. J., Galián, J. A., Botella, C., Moya‐Quiles, M. R., Muro-Pérez, M., Minguela, A., et al. (2024) · Biomedicines · doi:10.3390/biomedicines12010116 · Cited by 9 · see citing works

MicroRNAs as monitoring markers for right-sided heart failure and congestive hepatopathy

Ionescu, R. F., & Creţoiu, S. M. (2021) · Journal of Medicine and Life · doi:10.25122/jml-2021-0071 · Cited by 9 · see citing works

3D genome-selected microRNAs to improve Alzheimer's disease prediction

Li, K., Chi, R., Liu, L., Feng, M., Su, K., Li, X., He, G., & Shi, Y. Y. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1059492 · Cited by 7 · see citing works

Deciphering the roles of cellular and extracellular non-coding RNAs in chemotherapy-induced cardiotoxicity

Feng, P., Yang, F., Zang, D., Bai, D., Xu, L., Fu, Y., You, R., Liu, T., & Yang, X. (2024) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-024-05143-5 · Cited by 5 · see citing works

First trimester circulating miR-208b-3p and miR-26a-1-3p are relevant to the prediction of gestational hypertension

Clément, A., Légaré, C., Desgagné, V., Thibeault, K., White, F., Scott, M. S., Jacques, P., Fraser, W. D., Perron, P., Guérin, R., et al. (2025) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-025-07349-x · Cited by 5 · see citing works

Noncoding RNAs in fish physiology and development: miRNAs as a cornerstone in gene networks

Solís, F. J. T., Fernandes, J. M. O., Sarropoulou, E., & Monzón, I. F. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822273-7.00012-4 · Cited by 4 · see citing works

INVESTIGATION OF MIR-155 LEVEL IN THE BLOOD OF PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA AND PH-NEGATIVE MYELOPROLIFERATIVE NEOPLASMS

Stolyar, M. A., Горбенко, А. С., Ивановна, Б. В., Martynova, E. V., Москов, В. И., Mikhalev, M. A., Ольховик, Т. И., Hazieva, A. S., & Olkhovskiy, I. A. (2020) · Russian Clinical Laboratory Diagnostics · doi:10.18821/0869-2084-2020-65-4-258-264 · Cited by 5 · see citing works

Analysis of nocturnal, hypoxia-induced miRNAs in sleep apnea patients

Goody, P. R., Nachtsheim, L., Hosen, M. R., von Krosigk, M., Christmann, D., Klußmann, J. P., Zietzer, A., Breitrück, N., Jansen, F., & Jansen, S. (2022) · PLoS ONE · doi:10.1371/journal.pone.0263747 · Cited by 4 · see citing works

Evaluation of Small Extracellular Vesicles Isolation Methods from Human Serum for Downstream miRNA Profiling

Sou, Y. L., Tan, P. P. S., Hendri, N. A. M., Ratnam, W., Karupaiah, T., Chilian, W. M., Zain, S. M., Kadir, S. Z. S. A., Pan, Y., & Pung, Y. F. (2025) · Malaysian Applied Biology · doi:10.55230/mabjournal.v54i1.3357 · Cited by 3 · see citing works

Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis

Ashique, S., Pal, R., Islam, A., Sharma, H., Mandal, S., Kumar, S., Singh, M., Selim, S., Jaouni, S. K. A., Raikar, A. S., et al. (2025) · Current Protein and Peptide Science · doi:10.2174/0113892037362309250319035758 · Cited by 3 · see citing works

Insights into the World of MicroRNAs

Greco, M., CHIEFARI, E. D., Mirabelli, M., Salatino, A., Pullano, S. A., Aversa, A., FOTI, D. P., & Brunetti, A. (2022) · Biomarkers in disease · doi:10.1007/978-3-031-08014-2_34 · Cited by 2 · see citing works

Small Noncoding RNA Expression in Cancer

Guisier, F., Barros‐Filho, M. C., Rock, L. D., Constantino, F. B., Minatel, B. C., Sage, A. P., Marshall, E. A., Martínez, V. D., & Lam, W. L. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.84270 · Cited by 2 · see citing works

Insights into the World of MicroRNAs

Greco, M., CHIEFARI, E. D., Mirabelli, M., Salatino, A., Pullano, S. A., Aversa, A., FOTI, D. P., & Brunetti, A. (2022) · Biomarkers in disease · doi:10.1007/978-3-030-81303-1_34-1 · Cited by 1 · see citing works

Ageing at Molecular Level: Role of MicroRNAs

Yadav, S., Sarkar, S., Pandey, A. K., & Singh, T. (2023) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-21410-3_9 · Cited by 1 · see citing works

MicroRNAs and synaptic dysfunction in Parkinson’s disease

Ogwo, M. N., Sharma, B., Goyal, G., Lakshmanaswamy, R., & Kumar, S. (2025) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2025.102673 · Cited by 1 · see citing works

Exosomal Non-coding RNAs

Prakash, R., Pande, K., & Kannan, A. (2021) · Handbook of Oxidative Stress in Cancer: Therapeutic Aspects · doi:10.1007/978-981-16-1247-3_74-1 · Cited by 1 · see citing works

Exosomal Non-coding RNAs

Prakash, R., Pande, K., & Kannan, A. (2022) · Handbook of Oxidative Stress in Cancer: Therapeutic Aspects · doi:10.1007/978-981-16-5422-0_74 · Cited by 1 · see citing works

Introduction to Online Nucleic Acid Databases for EV Research

Hu, J., & Huang, S. (2024) · Springer eBooks · doi:10.1007/978-981-99-8365-0_31 · Cited by 1 · see citing works

Integration Analysis of miRNA Circulating Expression Following Cerebellar Transcranial Direct Current Stimulation in Patients with Ischemic Stroke

Pang, X., Xiao, F., Zheng, T., Zhao, L., Ge, X., Xie, S., Zhang, Z., Xu, N., Wei, Z., & Xiao, Z. (2024) · Biochemical Genetics · doi:10.1007/s10528-024-10912-4 · Cited by 1 · see citing works

The Effect of Mixing Seminal Fluid and Vaginal Secretion on the Expression of miRNA Markers in a Simulated Forensic Scientific Detection

Al-Mawlah, Y. H., Jebor, M. A., & Abdulla, A. A. (2021) · Annals of the Romanian Society for Cell Biology · Cited by 1 · see citing works

Épigénétique de la spondyloarthrite

Cherqaoui, B., Crémazy, F. G. E., Hue, C., Garchon, H., Bréban, M., & Costantino, F. (2020) · Revue du Rhumatisme · doi:10.1016/j.rhum.2020.11.004

MicroRNAs and Vascular Activity

Gao, Y. (2022) · Springer eBooks · doi:10.1007/978-981-19-7122-8_15

Methods for assessing the effect of microRNA on stemness genes

Pershina, A. G., Nevskaya, K. V., Morozov, K. R., & Литвяков, Н. В. (2023) · Bulletin of Siberian Medicine · doi:10.20538/1682-0363-2022-4-170-182

Adapting Genome-wide microRNA Discovery and Target Prediction to Specific Species

Ajila, V. (2023) · doi:10.22215/etd/2023-15614

Expressão de microRNA no plasma e suas relações com biomarcadores cardiometabólicos e dieta em idosos participantes de estudo de base populacional (ISA Capital)

de Carvalho, G. B. (2024) · doi:10.11606/t.6.2024.tde-28032024-091843

Additional file 1 of Circulating MiR-1290 as a potential diagnostic and disease monitoring biomarker of human gastrointestinal tumors

Xu, L., Cai, Y., Chen, X., Zhu, Y., & Cai, J. (2021) · Figshare · doi:10.6084/m9.figshare.16570109

Associação entre microRNA circulantes, biomarcadores cardiometabólicos e dieta em indivíduos adultos participantes de um estudo de base populacional - ISA-Capital

Brandão‐Lima, P. N. (2024) · doi:10.11606/t.6.2024.tde-02082024-151203

An Integrative Framework Identifies Cooperative Targeting of Host Pathways by Tick Salivary miRNAs

Medina, J. M., Barturen, G., Kotsyfakis, M., & Hackenberg, M. (2026) · Computational and Structural Biotechnology Journal · doi:10.34133/csbj.0106

Impending Role of Exosomal miRNA as Substantial Players in Early Cancer Diagnostics

Prakash, R., Natesh, A., Kubendiran, K., Palakshappa, S. S., & Kannan, A. (2026) · Advances in biochemistry in health and disease · doi:10.1007/978-3-032-08824-6_6

MicroRNAs in osteoporosis: current evidence and clinical perspectives

Świecka, M., & Chmielewski, M. S. (2026) · Reumatologia/Rheumatology · doi:10.5114/reum/220000

Small RNAs, big impact: microRNAs in malaria pathogenesis, therapeutic opportunities, and challenges

Metwally, N. G., Tauler, M. D. P. M., Torabi, H., & Bruchhaus, I. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2026.1883875

MicroRNAs in veterinary viral diseases: A comprehensive review from molecular mechanisms to clinical translation

Choobineh, M. R., Choobineh, D., & Hajieghrari, B. (2026) · Virus Research · doi:10.1016/j.virusres.2026.199800

Extracellular miRNAs: the mystery of their origin and function

Turchinovich, A. A., Weiz, L., & Burwinkel, B. (2012) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2012.08.003 · Cited by 520 · see citing works

The origin, function, and diagnostic potential of extracellular microRNAs in human body fluids

Liang, H., Gong, F., Zhang, S., Zhang, C., Zen, K., & Chen, X. (2013) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1208 · Cited by 82 · see citing works

doi: 10.3389/fgene.2013.00119 Circulating miRNAs: cell–cell communication function?

Turchinovich, A., Samatov, T. R., Tonevitsky, A. G., Burwinkel, B., Cho, W., Elizabeth, Q., Molecular, A. T., & German, E. C. (2013)

The origin, function and diagnostic potential of extracellular microRNA in human body fluids

(2014) · Frontiers research topics · doi:10.3389/978-2-88919-242-7 · Cited by 3 · see citing works

Circulating miRNAs: cell–cell communication function?

Turchinovich, A. A., Samatov, T. R., Tonevitsky, A., & Burwinkel, B. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00119 · Cited by 370 · see citing works