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Prevalence of dyslipidemia and achievement of low-density lipoprotein cholesterol targets in Chinese adults: A nationally representative survey of 163,641 adults

Zhang, Mei, Deng, Qian, Wang, Linhong, Huang, Zhengjing, Zhou, Maigeng, Li, Yichong, Zhao, Zhenping, Zhang, Yawei, Wang, Limin·2018·International Journal of Cardiology

Abstract

BACKGROUND Elevated serum total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels are established risk factors for cardiovascular diseases, a leading cause of death in China. We sought to assess the latest levels of serum lipids, prevalence of dyslipidemia and achievement of LDL-C lowering targets among Chinese adults. METHODS Data was obtained from a national representative survey recruited 163,641 adults aged >18years in mainland China between 2013 and 2014. Fasting serum total cholesterol (TC), LDL-C, high-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) were measured by standard methods. Multiple logistic regression was preformed to estimate potential risk factors for dyslipidemias. Proportion of residents not achieve the therapeutic goals for LDL-C by atherosclerotic cardiovascular diseases (ASCVD) risk stratification were evaluated. RESULTS Nationally, the population-weighted means of TC, HDL-C, and LDL-C, and median of TG were 4.70, 1.35, 2.88, and 1.49mmol/L, respectively. The prevalence of high TC, high LDL-C, low HDL-C and high TG was 6.9%, 8.1%, 20.4% and 13.8%. Among individuals with high ASCVD risk, 74.5% had uncontrolled LDL-C levels (<2.6mmol/L) and 5.5% of them were treated. For very-high-risk individuals, 93.2% didn't achieve their LDL-lowering goals (<1.8mmol/L) and 14.5% of them were treated. CONCLUSIONS Chinese adults currently experienced a high prevalence of abnormal serum lipid levels, more common in urban adults or those with obesity or central obesity. A significant proportion of people with high or very high ASCVD risk didn't meet LDL-C targets. Improvements in achievement of lipid-level targets and of LDL-lowering therapy rates based on ASCVD risk stratification were necessary.

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Metadata

Authors
Zhang, M., Deng, Q., Wang, L., Huang, Z., Zhou, M., Li, Y., Zhao, Z., Zhang, Y., & Wang, L.
Venue
International Journal of Cardiology
Publisher
Elsevier BV
Published
2018-06
Volume
260
Pages
196-203
ISSN
0167-5273 (ISSN-L)
OpenAlex
W2796185602
Cited by
253
References
6
FWCI
20.50
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Prevalence of dyslipidemia and achievement of low-density lipoprotein cholesterol targets in Chinese adults: A nationally representative survey of 163,641 adults. https://app.cochat.ai/papers/10.1016/j.ijcard.2017.12.069
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Zhang, M., Deng, Q., Wang, L., Huang, Z., Zhou, M., Li, Y., Zhao, Z., Zhang, Y., & Wang, L. (2018). Prevalence of dyslipidemia and achievement of low-density lipoprotein cholesterol targets in Chinese adults: A nationally representative survey of 163,641 adults. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2017.12.069

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