The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Evaluation of a novel antigen-based rapid detection test for the diagnosis of SARS-CoV-2 in respiratory samples
Open accessAbstract
OBJECTIVES: In the context of the coronavirus disease 2019 (COVID-19) pandemic, the development and validation of rapid and easy-to-perform diagnostic methods are of high priority. This study was performed to evaluate a novel rapid antigen detection test (RDT) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in respiratory samples. METHODS: The fluorescence immunochromatographic SARS-CoV-2 antigen test (Bioeasy Biotechnology Co., Shenzhen, China) was evaluated using universal transport medium with nasopharyngeal (NP) and oropharyngeal (OP) swabs from suspected COVID-19 cases. Diagnostic accuracy was determined in comparison to SARS-CoV-2 real-time (RT)-PCR. RESULTS: A total of 127 samples were included; 82 were RT-PCR-positive. The median patient age was 38 years, 53.5% were male, and 93.7% were from the first week after symptom onset. Overall sensitivity and specificity were 93.9% (95% confidence interval 86.5-97.4%) and 100% (95% confidence interval 92.1-100%), respectively, with a diagnostic accuracy of 96.1% and Kappa coefficient of 0.9. Sensitivity was significantly higher in samples with high viral loads. CONCLUSIONS: The RDT evaluated in this study showed a high sensitivity and specificity in samples mainly obtained during the first week of symptoms and with high viral loads, despite the use of a non-validated sample material. The assay has the potential to become an important tool for early diagnosis of SARS-CoV-2, particularly in situations with limited access to molecular methods.
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Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR
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Cited by
Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection
Dinnes, J., Deeks, J. J., Adriano, A., Berhane, S., Davenport, C., Dittrich, S., Emperador, D., Takwoingi, Y., Cunningham, J., Beese, S., et al. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013705 · Cited by 1,156
Self-citationRapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection
Dinnes, J., Deeks, J. J., Berhane, S., Taylor, M., Adriano, A., Davenport, C., Dittrich, S., Emperador, D., Takwoingi, Y., Cunningham, J., et al. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013705.pub2 · Cited by 591
Self-citationDiagnostics for COVID-19: moving from pandemic response to control
Peeling, R. W., Heymann, D. L., Teo, Y.-Y., & Garcia, P. J. (2022) · The Lancet · doi:10.1016/s0140-6736(21)02346-1 · Cited by 486
Brümmer, L. E., Katzenschlager, S., Gaeddert, M., Erdmann, C., Schmitz, S., Bota, M., Grilli, M., Larmann, J., Weigand, M. A., Pollock, N. R., et al. (2021) · PLOS Medicine · doi:10.1371/journal.pmed.1003735 · Cited by 298
Metadata
- Authors
- Porte, L., Legarraga, P., Vollrath, V., Aguilera, X., Munita, J. M., Araos, R., Pizarro, G., Vial, P., Iruretagoyena, M., Dittrich, S., & Weitzel, T.
- Venue
- International Journal of Infectious Diseases
- Publisher
- Elsevier BV
- Published
- 2020-10
- Volume
- 99
- Pages
- 328-333
- ISSN
- 1201-9712 (ISSN-L)
- OpenAlex
- W3017023889
- Cited by
- 371
- References
- 39
- FWCI
- 9.99
- Type
- journal article
- Language
- en
- Open access
- gold
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- Porte, L., Legarraga, P., Vollrath, V., Aguilera, X., Munita, J. M., Araos, R., Pizarro, G., Vial, P., Iruretagoyena, M., Dittrich, S., & Weitzel, T. (2020). Evaluation of a novel antigen-based rapid detection test for the diagnosis of SARS-CoV-2 in respiratory samples. International Journal of Infectious Diseases. https://doi.org/10.1016/j.ijid.2020.05.098
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
