The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Bacteriophage endolysins: A novel anti-infective to control Gram-positive pathogens
Open accessAbstract
Endolysins (or lysins) are highly evolved enzymes produced by bacteriophage (phage for short) to digest the bacterial cell wall for phage progeny release. In Gram-positive bacteria, small quantities of purified recombinant lysin added externally results in immediate lysis causing log-fold death of the target bacterium. Lysins have been used successfully in a variety of animal models to control pathogenic antibiotic-resistant bacteria found on mucosal surfaces and infected tissues. Their specificity for the pathogen without disturbing the normal flora, the low chance of bacterial resistance, and their ability to kill colonizing pathogens on mucosal surfaces, a capacity previously unavailable, make them ideal anti-infectives in an age of mounting resistance. Here we review the current literature showing the effectiveness of these enzymes in controlling a variety of infections.
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Cites
Nasal Carriage as a Source of Staphylococcus aureus Bacteremia
von Eiff, C., Becker, K., Machka, K., Stammer, H., & Peters, G. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440102 · Cited by 1,984
Insights into the Interaction between Influenza Virus and Pneumococcus
McCullers, J. A. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.00058-05 · Cited by 846
Holins: The Protein Clocks of Bacteriophage Infections
Wang, I.-N., Smith, D. L., & Young, R. (2000) · Annual Review of Microbiology · doi:10.1146/annurev.micro.54.1.799 · Cited by 806
Bacteriophage lysis: mechanism and regulation
Young, R. (1992) · Microbiological Reviews · doi:10.1128/mmbr.56.3.430-481.1992 · Cited by 773
A bacteriolytic agent that detects and kills Bacillus anthracis
Schuch, R., Nelson, D., & Fischetti, V. A. (2002) · Nature · doi:10.1038/nature01026 · Cited by 656
Self-citationNelson, D., Loomis, L., & Fischetti, V. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061038398 · Cited by 578
Self-citationBacteriophage endolysins — current state of research and applications
Loessner, M. J. (2005) · Current Opinion in Microbiology · doi:10.1016/j.mib.2005.06.002 · Cited by 537
Rapid Killing of Streptococcus pneumoniae with a Bacteriophage Cell Wall Hydrolase
Loeffler, J. M., Nelson, D., & Fischetti, V. A. (2001) · Science · doi:10.1126/science.1066869 · Cited by 517
Self-citationPhages will out: strategies of host cell lysis
Young, R., Wang, I.-N., & Roof, W. D. (2000) · Trends in Microbiology · doi:10.1016/s0966-842x(00)01705-4 · Cited by 433
Bacteriophage therapy: a revitalized therapy against bacterial infectious diseases
Matsuzaki, S., Rashel, M., Uchiyama, J., Sakurai, S., Ujihara, T., Kuroda, M., Imai, S., Ikeuchi, M., Tani, T., Fujieda, M., et al. (2005) · Journal of Infection and Chemotherapy · doi:10.1007/s10156-005-0408-9 · Cited by 409
Cited by
Phage Lysis: Multiple Genes for Multiple Barriers
Cahill, J., & Young, R. (2019) · Advances in Virus Research · doi:10.1016/bs.aivir.2018.09.003 · Cited by 319
Maciejewska, B., Olszak, T., & Drulis-Kawa, Z. (2018) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-8811-1 · Cited by 222
Bacteriophage virion-associated peptidoglycan hydrolases: potential new enzybiotics
Rodríguez-Rubio, L., Martínez, B., Donovan, D. M., Rodríguez, A., & García, P. (2013) · Critical Reviews in Microbiology · doi:10.3109/1040841x.2012.723675 · Cited by 173
Rello, J., van Engelen, T. S. R., Alp, E., Calandra, T., Cattoir, V., Kern, W. V., Netea, M. G., Nseir, S., Opal, S. M., van de Veerdonk, F. L., et al. (2018) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2018.03.011 · Cited by 143
Metadata
- Authors
- Fischetti, V. A.
- Venue
- International Journal of Medical Microbiology
- Publisher
- Elsevier BV
- Published
- 2010-08
- Volume
- 300
- Issue
- 6
- Pages
- 357-362
- ISSN
- 1438-4221 (ISSN-L)
- OpenAlex
- W2100402024
- Cited by
- 438
- References
- 54
- FWCI
- 25.19
- Type
- journal article
- Language
- en
- Open access
- green
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- Fischetti, V. A. (2010). Bacteriophage endolysins: A novel anti-infective to control Gram-positive pathogens. International Journal of Medical Microbiology. https://doi.org/10.1016/j.ijmm.2010.04.002
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
