The incidence of cholelithiasis after sleeve gastrectomy and its association with weight loss: a two-centre retrospective cohort study
Open accessAbstract
INTRODUCTION: Gallstones commonly develop after Roux-en-Y gastric bypass and other bariatric surgery; however, incidence of gallstone development after SG has not been adequately studied. METHODS: We conducted a retrospective cohort study of patients who underwent SG at two institutions from January 1, 2011 to December 31, 2012. Patients with previous cholecystectomy, preexisting gallstones, gallbladder polyps, or the absence of preoperative abdominal imaging were excluded. Follow-up abdominal ultrasonography was performed once the patients achieved 80-lb weight loss, became symptomatic, or reached one-year post-surgery. The incidence of gallstones and symptomatic gallstones and/or bile sludge was calculated. Different parameters of early and late postoperative weight loss were compared between the patients who developed gallstones and those who did not. RESULTS: During the study period, 253 underwent laparoscopic sleeve gastrectomy. Ultimately, 96 patients met inclusion criteria and were evaluated. The incidence of gallstone formation was 47.9% (46/96), and the incidence of symptomatic gallstones was 22.9% (22/96). None of the weight loss parameters during the early and late postoperative period were significantly different between the patients who developed gallstones and those who did not. CONCLUSION: Gallstones are a common complication after rapid weight loss from SG. Our data suggest that gallstone formation during the weight loss period is not associated with amount or rate of weight loss both during the early or late postoperative period.
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Gallstones and gallbladder removal are common in people who lose weight rapidly through very-low-calorie diets or bariatric surgery.
“Cholelithiasis and cholecystectomy are common in patients who achieve rapid weight loss with very-low-calorie diets(54) or bariatric surgery.(55)”
From Semaglutide for the treatment of obesity (2023) · cites this paper as [55]
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- Authors
- Manatsathit, W., Leelasinjaroen, P., Al-Hamid, H., Szpunar, S., & Hawasli, A.
- Affiliations
- St. John Hospital & Medical Center (US)
- Botsford Hospital (US)
- Corresponding author
- Hawasli, Abdelkader
- Venue
- International Journal of Surgery
- Published
- 2016-06
- Volume
- 30
- Pages
- 13-18
- ISSN
- 1743-9159 (ISSN-L)
- 1743-9191
- OpenAlex
- W2340147359
- Cited by
- 78
- References
- 25
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 4 · 2023: 20 · 2022: 6 · 2021: 5 · 2020: 14 · 2019: 8 · 2018: 6 · 2017: 1 · 2016: 2
- FWCI
- 6.27
- Type
- journal article
- Language
- en
- Update notices
- erratum (2016-11-01)
- Open access
- bronze
- doi.org
- Licence
- Locations
- International Journal of Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Gallbladder and Bile Duct Disorders
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Biliary and Gastrointestinal Fistulas
- Keywords
- gallstones, sleeve gastrectomy, bariatric surgery, weight loss, postoperative complications, symptomatic gallstones, bile sludge, gallstone incidence
- MeSH terms
- Adult, Bile, Female, Gastrectomy, Humans, Male, Middle Aged, Obesity, Morbid, Postoperative Period, Retrospective Studies, Gastric Bypass, Weight Loss, Incidence, Gallstones, Bariatric Surgery
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