Alveolar Macrophage in the Driver's Seat
Open accessAbstract
Although alveolar macrophages are normally quiescent to prevent damaging the alveoli, in this issue of Immunity, Takabayshi et al. (2006) demonstrate that alveolar macrophages can self-regulate their function on demand to mount an appropriate immune response.
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Phagocytized objects are enclosed in a phagolysosome and degraded via oxidative and/or enzymatic processes, or if non-degradable transported from the lung parenchyma via the mucociliary escalator to the larynx.
“Phagocytized objects are enclosed in a phagolysosome and degraded via oxidative and/or enzymatic processes, or, if non-degradable, transported from the lung parenchyma via the mucociliary escalator to the larynx for removal from the body [9, 10].”
From Macrophages bend long fibres with flexural rigidity lower than 3 mN·nm2 to avoid frustrated phagocytosis (2026) · cites this paper as [9]
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RetractedRETRACTED: Induction of a Homeostatic Circuit in Lung Tissue by Microbial Compounds
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- Authors
- Lambrecht, B. N.
- Affiliations
- Erasmus MC (NL)
- Corresponding author
- Lambrecht, Bart N.
- ORCID
- Lambrecht, Bart N.
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2006-04
- Volume
- 24
- Issue
- 4
- Pages
- 366-368
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W2006616223
- Cited by
- 242
- References
- 12
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 7 · 2023: 12 · 2022: 9 · 2021: 6 · 2020: 13 · 2019: 16 · 2018: 15 · 2017: 16 · 2016: 14 · 2015: 11 · 2014: 19 · 2013: 13 · 2012: 22
- FWCI
- 4.25
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Immunity (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Phagocytosis and Immune Regulation
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Keywords
- alveolar macrophages, lung immunity, macrophage activation
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