Interleukin-33-Dependent Innate Lymphoid Cells Mediate Hepatic Fibrosis

Liver fibrosis

Bataller, R., & Brenner, D. A. (2005) · Journal of Clinical Investigation · doi:10.1172/jci24282 · Cited by 4,958

IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines

Schmitz, J., Owyang, A. M., Oldham, E. R., Song, Y., Murphy, E., McClanahan, T. K., Zurawski, G., Moshrefi, M., Qin, J., Li, X., et al. (2005) · Immunity · doi:10.1016/j.immuni.2005.09.015 · Cited by 3,773

Mechanisms of Hepatic Fibrogenesis

Friedman, S. L. (2008) · Gastroenterology · doi:10.1053/j.gastro.2008.03.003 · Cited by 2,687

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Neill, D. R., Wong, S. H., Bellosi, A., Flynn, R. J., Daly, M. G., Langford, T. K. A., Bucks, C. M., Kane, C. M., Fallon, P. G., Pannell, R., et al. (2010) · Nature · doi:10.1038/nature08900 · Cited by 2,079

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

Moro, K., Yamada, T., Tanabe, M., Takeuchi, T., Ikawa, T., Kawamoto, H., Furusawa, J.-I., Ohtani, M., Fujii, H., & Koyasu, S. (2009) · Nature · doi:10.1038/nature08636 · Cited by 1,994

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA

Liu, F., Song, Y. K., & Liu, D. (1999) · Gene Therapy · doi:10.1038/sj.gt.3300947 · Cited by 1,728

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

Monticelli, L. A., Sonnenberg, G. F., Abt, M. C., Alenghat, T., Ziegler, C. G. K., Doering, T. A., Angelosanto, J., Laidlaw, B. J., Yang, C. Y., Sathaliyawala, T., et al. (2011) · Nature Immunology · doi:10.1038/ni.2131 · Cited by 1,327

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

Monticelli (2011) · PubMed · doi:10.1031/ni.2131 · Cited by 1,286

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

Mjösberg, J. M., Trifari, S., Crellin, N. K., Peters, C. P., van Drunen, C. M., Piet, B., Fokkens, W. J., Cupedo, T., & Spits, H. (2011) · Nature Immunology · doi:10.1038/ni.2104 · Cited by 1,166

Systemically dispersed innate IL-13–expressing cells in type 2 immunity

Price, A. E., Liang, H.-E., Sullivan, B. M., Reinhardt, R. L., Eisley, C. J., Erle, D. J., & Locksley, R. M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1003988107 · Cited by 1,134

TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis

Singh, H. D., Otano, I., Rombouts, K., Singh, K. P., Peppa, D., Gill, U. S., Böttcher, K., Kennedy, P. T. F., Oben, J. A., Pinzani, M., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-05845-5 · Cited by 20

Innate lymphoid cell-derived cytokines in autoimmune diseases

Li, S., Yang, D., Peng, T., Wu, Y., Tian, Z., & Ni, B. (2017) · Journal of Autoimmunity · doi:10.1016/j.jaut.2017.05.001 · Cited by 19

Role of Innate lymphoid Cells in Obesity and Insulin Resistance

Chen, H., Sun, L., Feng, L., Yin, Y., & Zhang, W. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.855197 · Cited by 20

Regulation of Progression and Resolution of Liver Fibrosis by Immune Cells

Koda, Y., Nakamoto, N., & Kanai∥, T. (2022) · Seminars in Liver Disease · doi:10.1055/a-1957-6384 · Cited by 19

Can Nutraceuticals Support the Treatment of MASLD/MASH, and thus Affect the Process of Liver Fibrosis?

Sokal-Dembowska, A., Jarmakiewicz-Czaja, S., Ferenc, K., & Filip, R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105238 · Cited by 19

From pathogenesis to therapy – Perspective on treatment strategies in fibrotic diseases

Ramming, A., Dees, C., & Distler, J. H. W. (2015) · Pharmacological Research · doi:10.1016/j.phrs.2015.06.012 · Cited by 19

Innate lymphoid cells involve in tumorigenesis

Tian, Z., van Velkinburgh, J. C., Wu, Y., & Ni, B. (2015) · International Journal of Cancer · doi:10.1002/ijc.29443 · Cited by 19

The Effect of Antifibrotic Drug Halofugine on Th17 Cells in Concanavalin A‐Induced Liver Fibrosis

Liang, J., Zhang, B., Shen, R., Liu, J., Gao, M., Geng, X.-C., Li, Y., Li, Y., & Zhang, W. (2014) · Scandinavian Journal of Immunology · doi:10.1111/sji.12144 · Cited by 19

Senescence and cell death in chronic liver injury: roles and mechanisms underlying hepatocarcinogenesis

Xiao, M., Chen, W., Wang, C., Wu, Y., Zhu, S., Zeng, C., Cai, Y., Liu, C., & He, Z. (2017) · Oncotarget · doi:10.18632/oncotarget.23622 · Cited by 21

Group 2 Innate Lymphoid Cells Participate in Renal Fibrosis in Diabetic Kidney Disease Partly via TGF-β1 Signal Pathway

Liu, C., Qin, L., Ding, J., Zhou, L., Gao, C., Zhang, T., Guo, M., Huang, W. G., Jiang, Z., Long, Y., et al. (2019) · Journal of Diabetes Research · doi:10.1155/2019/8512028 · Cited by 19

Clinical Value of Serum Interleukin‐33 Biomarker in Infants With Neonatal Cholestasis

Behairy, O. G. A., Elsadek, A. E., Behiry, E. G., Elhenawy, I. A., Shalan, N. H., & Sayied, K. R. (2019) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000002565 · Cited by 19

Identification and characterization of a hepatic IL-13–producing ILC3-like population potentially involved in liver fibrosis

Raabe, J., Kaiser, K. M., ToVinh, M., Finnemann, C., Lutz, P. L., Hoffmeister, C., Bischoff, J., Goeser, F., Kaczmarek, D. J., Glowka, T. R., et al. (2023) · Hepatology · doi:10.1097/hep.0000000000000350 · Cited by 18

Neutrophil extracellular traps (NETs) and fibrotic diseases

Wu, X., & Yang, Y. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112085 · Cited by 19

Type 2 Innate Lymphoid Cells in Liver and Gut: From Current Knowledge to Future Perspectives

Ochel, A., Tiegs, G., & Neumann, K. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20081896 · Cited by 18

Innate Lymphoid Cells: A Promising New Regulator in Fibrotic Diseases

Zhang, Y., Tang, J., Tian, Z., van Velkinburgh, J. C., Song, J. J., Wu, Y., & Ni, B. (2015) · International Reviews of Immunology · doi:10.3109/08830185.2015.1068304 · Cited by 18

Roles of innate lymphoid cells in metabolic and alcohol-associated liver diseases

Bourinet, M., Anty, R., Gual, P., & Luci, C. (2023) · JHEP Reports · doi:10.1016/j.jhepr.2023.100962 · Cited by 20

Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease

Wegrzyniak, O., Rosestedt, M., & Eriksson, O. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147348 · Cited by 17

Human Ascariasis Increases the Allergic Response and Allergic Symptoms

Caraballo, L. R., Acevedo, N., & Buendía, E. (2015) · Current Tropical Medicine Reports · doi:10.1007/s40475-015-0058-7 · Cited by 17

Innate lymphoid cells and fibrotic regulation

Horsburgh, S., Todryk, S. M., Ramming, A., Distler, J. H. W., & O’Reilly, S. (2017) · Immunology Letters · doi:10.1016/j.imlet.2017.08.022 · Cited by 18

Plasticity of Innate Lymphoid Cells in Cancer

Heinrich, B., & Korangy, F. (2022) · Frontiers in Immunology · doi:10.3389/fimmu-13-886520 · Cited by 16

Plasticity between type 2 innate lymphoid cell subsets and amphiregulin expression regulates epithelial repair in biliary atresia

Russi, A. E., Shivakumar, P., Luo, Z., & Bezerra, J. A. (2023) · Hepatology · doi:10.1097/hep.0000000000000418 · Cited by 18

Innate immune cells link dietary cues to normal and abnormal metabolic regulation

Zhang, P., Watari, K., & Karin, M. (2025) · Nature Immunology · doi:10.1038/s41590-024-02037-y · Cited by 16

Innate Lymphoid Cells in Renal Inflammation

Becker, M., Gnirck, A.-C., & Turner, J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00072 · Cited by 16

The Interleukin-33–Group 2 Innate Lymphoid Cell Axis Represents a Potential Adjuvant Target To Increase the Cross-Protective Efficacy of Influenza Vaccine

Williams, C. M., Roy, S. B., Califano, D., McKenzie, A. N. J., Metzger, D. W., & Furuya, Y. (2021) · Journal of Virology · doi:10.1128/jvi.00598-21 · Cited by 16

Molecular signature and functional analysis of uterine ILCs in mouse pregnancy

Li, M., Gao, Y., Liang, Y., Huang, D., Shen, J., Liu, M., Ren, C., & Hou, X. (2017) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2017.09.003 · Cited by 16

Vitamin A deficiency execrates Lewis lung carcinoma via induction of type 2 innate lymphoid cells and alternatively activates macrophages

Cui, W., Zhang, W., Yuan, X., Liu, S., Li, M., Niu, J., Zhang, P., & Li, D. (2019) · Food Science & Nutrition · doi:10.1002/fsn3.961 · Cited by 16

Crosstalk in extrahepatic and hepatic system in NAFLD / NASH

Duan, Y., Yang, Y. Z., Zhao, S., Bai, Y., Yao, W., Gao, X., & Yin, J. (2024) · Liver International · doi:10.1111/liv.15967 · Cited by 16

Cell Therapy in Chronic Liver Disease

Alhomrani, M., Lim, R., & Sievert, W. (2016) · Stem cells in clinical applications · doi:10.1007/978-3-319-46693-4_2 · Cited by 15

Wnt2b attenuates HSCs activation and liver fibrosis through negative regulating TLR4 signaling

Yuan, Y., Han, Q., Li, S., Tian, Z., & Zhang, J. (2017) · Scientific Reports · doi:10.1038/s41598-017-04374-5 · Cited by 15

The blockade of interleukin‐33 released by hepatectomy would be a promising treatment option for cholangiocarcinoma

Nagaoka, S., Yamada, D., Eguchi, H., Yokota, Y., Iwagami, Y., Asaoka, T., Noda, T., Kawamoto, K., Gotoh, K., Kobayashi, S., et al. (2020) · Cancer Science · doi:10.1111/cas.14709 · Cited by 13

In drug-induced, immune-mediated hepatitis, interleukin-33 reduces hepatitis and improves survival independently and as a consequence of FoxP3+ T-cell activity

Cottagiri, M., Nyandjo, M., Stephens, M., Mantilla, J. J., Saito, H., Mackay, I. R., Rose, N. R., & Njoku, D. B. (2018) · Cellular and Molecular Immunology · doi:10.1038/s41423-018-0087-y · Cited by 15

Alcohol-mediated susceptibility to lung fibrosis is associated with group 2 innate lymphoid cells in mice

Chen, L., Sun, R., Lei, C., Xu, Z., Song, Y., & Deng, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1178498 · Cited by 14

Retinoic acid drives intestine-specific adaptation of effector ILC2s originating from distant sites

Shaikh, N., Waterhölter, A., Gnirck, A.-C., Becker, M., Adamiak, V., Henneken, L., Wunderlich, M., Hartmann, W., Linnemann, L. C., Huber, T. B., et al. (2023) · The Journal of Experimental Medicine · doi:10.1084/jem.20221015 · Cited by 14

Lung type 3 innate lymphoid cells respond early following Mycobacterium tuberculosis infection

Das, S., Chauhan, K. S., Ahmed, M., Akter, S., Lu, L., Colonna, M., & Khader, S. A. (2024) · mBio · doi:10.1128/mbio.03299-23 · Cited by 14

Early Persistent Blood Eosinophilia in Necrotizing Enterocolitis Is a Predictor of Late Complications

Nolan, L. S., Sherman, J., Miller, M. M., Zaghouani, H., & Sherman, M. P. (2015) · Neonatology · doi:10.1159/000431305 · Cited by 14

ILC2 Activation by Protozoan Commensal Microbes

Burrows, K., Ngai, L., Wong, F., Won, D., & Mortha, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20194865 · Cited by 14

IL-33/Regulatory T-Cell Axis Suppresses Skin Fibrosis

Cheon, S. S. Y., Park, J. H., Ameri, A. H., Lee, R. T., Nazarian, R. M., & Demehri, S. (2022) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2022.03.009 · Cited by 13

Full Length Interleukin 33 Aggravates Radiation-Induced Skin Reaction

Kurow, O., Frey, B., Schuster, L., Schmitt, V., Adam, S., Hahn, M., Gilchrist, D. S., McInnes, I. B., Wirtz, S. J., Gaipl, U. S., et al. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00722 · Cited by 16

ST2 blockade mitigates peritoneal fibrosis induced by TGF‐β and high glucose

Kim, Y. C., Kim, K. H., Lee, S., Jo, J., Park, J. Y., Park, M., Tsogbadrakh, B., Lee, J. P., Lee, J. W., Kim, D. K., et al. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14571 · Cited by 14

Ambiguous roles and potential therapeutic strategies of innate lymphoid cells in different types of tumor (Review)

Wang, S., Wu, P., Chen, Y., & Chai, Y. (2020) · Oncology Letters · doi:10.3892/ol.2020.11736 · Cited by 14

Systemic administration of IL‐33 induces a population of circulating KLRG1 hi type 2 innate lymphoid cells and inhibits type 1 innate immunity against multiple myeloma

Guillerey, C., Stannard, K. A., Chen, J., Krumeich, S., Miles, K. M., Nakamura, K., Smith, J. L., Yu, Y., Ng, S. S., Harjunpää, H., et al. (2020) · Immunology and Cell Biology · doi:10.1111/imcb.12390 · Cited by 14

The IL-33/ST2 pathway is not essential to Th2 stimulation but is key for modulation and survival during chronic infection with Schistosoma mansoni in mice

Maggi, L., Rocha, I. C., Camelo, G. M. A., Fernandes, V. R., & Negrão‐Corrêa, D. A. (2020) · Cytokine · doi:10.1016/j.cyto.2020.155390 · Cited by 14

Innate lymphoid cells in the spotlight: from biomarkers to blueprint for innovative immunotherapy

Kuo, I.-C., Brassard, J., Zandstra, P. W., & McNagny, K. M. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1655730 · Cited by 13

Mast Cell and Innate Immune Cell Communication in Cholestatic Liver Disease

Bernard, J. K., Marakovits, C. N., Smith, L., & Francis, H. (2023) · Seminars in Liver Disease · doi:10.1055/a-2104-9034 · Cited by 13

Exploring the Impact of Different Inflammatory Cytokines on Hepatitis C Virus Infection

Din, N. G. B. E., & Farouk, S. (2024) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2024.0003 · Cited by 13

Inflammatory and Non-Inflammatory Mechanisms Controlling Cirrhosis Development

Sánchez, P. S., Rigual, M. D. M., & Djouder, N. (2021) · Cancers · doi:10.3390/cancers13205045 · Cited by 13

Expression and potential roles of IL-33/ST2 in the immune regulation during Clonorchis sinensis infection

Yu, Q., Li, X., Cheng, X.-D., Shen, L., Fan, F., Zhang, B., Hua, H. M., Yan, C., Tang, R., & Zheng, K. (2016) · Parasitology Research · doi:10.1007/s00436-016-4974-9 · Cited by 13

Number and function of circulatory helper innate lymphoid cells are unaffected by immunosuppressive drugs used in solid organ recipients – a single centre cohort study

Gómez‐Massa, E., Talayero, P., Utrero‐Rico, A., Laguna‐Goya, R., Andrés, A., Mancebo, E., Leivas, A., Fernandez, N. I. P., Justo, I., Romero, C. J., et al. (2020) · Transplant International · doi:10.1111/tri.13567 · Cited by 13

Type 2 innate lymphoid cells are protective against hepatic ischaemia/reperfusion injury

Cao, Q., Wang, R., Niu, Z., Chen, T., Azmi, F., Read, S. A., Chen, J., Lee, V. W., Zhou, C., Julovi, S. M., et al. (2023) · JHEP Reports · doi:10.1016/j.jhepr.2023.100837 · Cited by 12

Mitochondrial GRIM19 Loss Induces Liver Fibrosis through NLRP3/IL33 Activation via Reactive Oxygen Species/NF-кB Signaling

Xu, X., Feng, J., Wang, X., Zeng, X., Luo, Y., He, X., Yang, M., Lv, T., Feng, Z., Bao, L., et al. (2024) · Journal of Clinical and Translational Hepatology · doi:10.14218/jcth.2023.00562 · Cited by 12

There’s no place like home: How local tissue microenvironments shape the function of innate lymphoid cells

Roberts, L. B., Kelly, A. M., & Hepworth, M. R. (2025) · Mucosal Immunology · doi:10.1016/j.mucimm.2025.01.012 · Cited by 12

Role of type 2 innate lymphoid cell and its related cytokines in tumor immunity

Wan, J., Cai, W., Wang, H., Cheng, J., Su, Z., Wang, S., & Xu, H. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.29287 · Cited by 11

Inflammatory Arthritis and Bone Metabolism Regulated by Type 2 Innate and Adaptive Immunity

Omata, Y., Frech, M., Saito, T., Schett, G. A., Zaiss, M. M., & Tanaka, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031104 · Cited by 12

Protective and pathogenic functions of innate lymphoid cells in transplantation

Mak, M. L., Reid, K. T., & Crome, S. Q. (2023) · Clinical & Experimental Immunology · doi:10.1093/cei/uxad050 · Cited by 12

Serum soluble ST2 is a promising prognostic biomarker in HBV-related acute-on-chronic liver failure

Jiang, S., Wang, P., Xiang, X., Mo, R., Lin, L., Bao, S., Lu, J. L., & Xie, Q. (2017) · Hepatobiliary & pancreatic diseases international · doi:10.1016/s1499-3872(16)60185-6 · Cited by 12

Enhanced activation of human NK cells by drug-exposed hepatocytes

Fasbender, F., Obholzer, M., Metzler, S., Stöber, R. M., Hengstler, J. G., & Watzl, C. (2020) · Archives of Toxicology · doi:10.1007/s00204-020-02668-8 · Cited by 12

Full-length IL-33 augments pulmonary fibrosis in an ST2- and Th2-independent, non-transcriptomic fashion

Luzina, I. G., Lockatell, V., Courneya, J.-P., Mei, Z., Fishelevich, R., Kopach, P., Pickering, E. M., Kang, P. H., Krupnick, A. S., Todd, N. W., et al. (2022) · Cellular Immunology · doi:10.1016/j.cellimm.2022.104657 · Cited by 11

A role for curcumin in preventing liver fibrosis in animals: a systematic review and meta-analysis

Huang, B.-H., Guo, Z., Lv, B., Zhao, X., Li, Y., & Lv, W. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1396834 · Cited by 14

Innate lymphoid cells, immune functional dynamics, epithelial parallels, and therapeutic frontiers in infections

Nouari, W., & Aribi, M. (2025) · International Reviews of Immunology · doi:10.1080/08830185.2025.2490233 · Cited by 11

Nucleotide-binding oligomerization domain 1 and gastrointestinal disorders

Watanabe, T., Asano, N., Kudo, M., & Strober, W. (2017) · Proceedings of the Japan Academy Series B · doi:10.2183/pjab.93.037 · Cited by 14

Hepatitis B virus X protein (HBx) promotes ST2 expression by GATA2 in liver cells

Chen, S., Wu, L., Peng, L., Wang, X., & Tang, N. (2020) · Molecular Immunology · doi:10.1016/j.molimm.2020.04.024 · Cited by 11

Signaling Pathways Tuning Innate Lymphoid Cell Response to Hepatocellular Carcinoma

Bourayou, E., & Golub, R. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.846923 · Cited by 11

Single cell RNA sequencing reveals regional heterogeneity of hepatobiliary innate lymphoid cells in a tissue-enriched fashion

Peters, A. L., Luo, Z., Li, J., Mourya, R., Wang, Y., Dexheimer, P. J., Shivakumar, P., Aronow, B. J., & Bezerra, J. A. (2019) · PLoS ONE · doi:10.1371/journal.pone.0215481 · Cited by 11

Collagen and Eosinophils in Jenny's Endometrium: Do They Differ With Endometrial Classification?

Miró, J., Gutiérrez-Reinoso, M. A., Aguiar‐Silva, J., Fernandes, C., Rebordão, M. R., Alexandre‐Pires, G., Catalán, J., & Ferreira-Dias, G. M. (2020) · Frontiers in Veterinary Science · doi:10.3389/fvets.2020.00631 · Cited by 11

Heme-Oxygenase-1 Attenuates Oxidative Functions of Antigen Presenting Cells and Promotes Regulatory T Cell Differentiation during Fasciola hepatica Infection

Costa, M., da Costa, V., Frigerio, S., Festari, M. F., Landeira, M., Rodríguez-Zraquia, S. A., Lores, P., Carasi, P., & Freire, T. (2021) · Antioxidants · doi:10.3390/antiox10121938 · Cited by 11

Interleukin-1 family cytokines in liver cell death: a new therapeutic target for liver diseases

Udomsinprasert, W. (2023) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2023.2285763 · Cited by 10

Impact of TRP Channels on Extracellular Matrix Remodeling: Focus on TRPV4 and Collagen

Wang, Q., Ji, C., Smith, P. C., & McCulloch, C. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25073566 · Cited by 11

Interleukin-33 promotes intrauterine adhesion formation in mice through the mitogen-activated protein kinase signaling pathway

Liu, D., Yuan, L., Xu, F., Ma, Y., Zhang, H., Jin, Y., Chen, M., Zhang, Z., & Luo, S. (2024) · Communications Biology · doi:10.1038/s42003-024-06709-1 · Cited by 11

Critical and diverse role of alarmin cytokines in parasitic infections

Xing, Z., Liu, S., & He, X. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1418500 · Cited by 10

Ambiguous roles of innate lymphoid cells in chronic development of liver diseases

Shen, Y. L., Li, J., Wang, S., & Jiang, W. (2018) · World Journal of Gastroenterology · doi:10.3748/wjg.v24.i18.1962 · Cited by 10

IL-33 in Tumor Immunity: Nothing to Sneeze At

Dominguez, D., Zhang, Y., & Zhang, B. (2018) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.2018026335 · Cited by 10

The transcription factor RelB restrains group 2 innate lymphoid cells and type 2 immune pathology in vivo

Zhang, L., Ying, Y., Chen, S., Arnold, P. R., Tian, F., Minze, L. J., Xiao, X., & Li, X. C. (2020) · Cellular and Molecular Immunology · doi:10.1038/s41423-020-0404-0 · Cited by 10

Innate lymphoid cells and infectious diseases

Yuan, T., Zhou, Q., Tian, Y., Ou, Y., Long, Y., & Tan, Y. (2024) · Innate Immunity · doi:10.1177/17534259241287311 · Cited by 9

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cells

Ning, M., Lu, D., Liang, D., & Ren, P. (2025) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2025.1513993 · Cited by 10

Proteomic-genomic adjustments and their confluence for elucidation of pathways and networks during liver fibrosis

Husain, H., Ahmad, R., Khan, A., Inamuddin, I., & Asiri, A. M. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.12.168 · Cited by 10

Schistosoma japonicum soluble egg antigen inhibits TNF-α-induced IL-34 expression in hepatic stellate cells

Chen, L., Yu, Y., Liu, E., Duan, L., Zhu, D., Chen, J., Dai, J. M., & Duan, Y. (2018) · Parasitology Research · doi:10.1007/s00436-018-6165-3 · Cited by 9

Innate lymphoid cells in antitumor immunity

Salomé, B., & Jandus, C. (2017) · Journal of Leukocyte Biology · doi:10.1189/jlb.5mr0617-266r · Cited by 9

Unveiling IL-33/ST2 Pathway Unbalance in Cardiac Remodeling Due to Obesity in Zucker Fatty Rats

Sitzia, C., Vianello, E., Dozio, E., Kalousová, M., Zima, T., Brizzola, S., Roccabianca, P., Tedeschi, G., Lamont, J. V., Tacchini, L., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24031991 · Cited by 8

Hepatocyte GPCR signaling regulates IRF3 to control hepatic stellate cell transdifferentiation

Yu, J.-H., Choi, M. G., Lee, N. Y., Kwon, A., Lee, E., & Koo, J. H. (2024) · Cell Communication and Signaling · doi:10.1186/s12964-023-01416-6 · Cited by 8

Fibrogenesis in chronic murine colitis is independent of innate lymphoid cells

Creyns, B., Cremer, J., Hertogh, G. D., Boon, L., Ferrante, M., Vermeire, S., Assche, G. V., Ceuppens, J. L., & Breynaert, C. M. (2020) · Immunity Inflammation and Disease · doi:10.1002/iid3.321 · Cited by 8

INTERLEUKIN 33 AND FIBROSIS: PATHOGENESIS UPDATED

Учасова, Е. Г., Gruzdeva, O. V., Dileva, Y. A., & Каретникова, В. Н. (2018) · Medical Immunology (Russia) · doi:10.15789/1563-0625-2018-4-477-484 · Cited by 8

From Autonomy to Integration, From Integration to Dynamically Balanced Integrated Co-existence: Non-aging as the Third Stage of Development

Salnikov, L., & Baramiya, M. G. (2021) · Frontiers in Aging · doi:10.3389/fragi.2021.655315 · Cited by 9

The Reaction of Innate Lymphoid Cells in the Mouse Female Genital Tract to Chlamydial Infection

Barth, S., Kirschnek, S., Ortmann, N., Tanriver, Y., & Häcker, G. A. (2021) · Infection and Immunity · doi:10.1128/iai.00800-20 · Cited by 8

Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition

Koyama, Y., Wang, P., Brenner, D. A., & Kisseleva, T. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800134-9.00006-3 · Cited by 9

Multifunctional roles of inflammation and its causative factors in primary liver cancer: A literature review

Chen, H., Huang, T.-X., Jiang, Y., Chen, X., & Wang, A.-F. (2023) · World Journal of Hepatology · doi:10.4254/wjh.v15.i12.1258 · Cited by 8

The Roles of T Cells in the Development of Metabolic Dysfunction‐Associated Steatohepatitis

Ge, Z., Wu, Q., Lv, C., & He, Q. (2025) · Immunology · doi:10.1111/imm.13943 · Cited by 7

The impact of T cells on immune-related liver diseases: an overview

Koda, Y., Kasuga, R., Taniki, N., Kanai∥, T., & Nakamoto, N. (2025) · Inflammation and Regeneration · doi:10.1186/s41232-025-00387-0 · Cited by 9

Fibroblasts as Immunological Sentinels in Cutaneous Inflammation: A Review

Quan, T. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15020556 · Cited by 7

Role of the IL-33/ST2 Activation Pathway in the Development of the Hepatic Fibrosis Induced by Schistosoma mansoni Granulomas in Mice

Maggi, L., Camelo, G. M. A., Rocha, I. C., Alves, W. P., Moreira, J. M. P., Pereira, T. A., Tafuri, W. L., Rabelo, É. M. L., Corrêa, A., Ecco, R., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241210237 · Cited by 7

High Expression of Interleukin-33/ST2 Predicts the Progression and Poor Prognosis in Chronic Hepatitis B Patients with Hepatic Flare

Yuan, W., Mei, X., Zhang, Y.-Y., Zhang, Z.-G., Zou, Y., Zhu, H., Liu, Y., Wang, J.-F., Qian, Z., & Lu, H. (2020) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2020.06.023 · Cited by 8

An in vivo gene delivery approach for the isolation of reasonable numbers of type 2 innate lymphoid cells

Frech, M., Knipfer, L., Wirtz, S. J., & Zaiss, M. M. (2020) · MethodsX · doi:10.1016/j.mex.2020.101054 · Cited by 7

Association between Melatonin Value and Interleukins1B, -18, and -33 Levels in Patients with Different Stages of Non-Alcoholic Fatty Liver Disease

Sohrabi, M., Ajdarkosh, H., Gholami, A., Amirkalali, B., Mansorian, M. R., Aten, S., Sohrabi, M., Nasiri‐Toosi, M., Zamani, F., & Keyvani, H. (2022) · Middle East Journal of Digestive Diseases · doi:10.34172/mejdd.2022.263 · Cited by 7

Preferential Reduction of Circulating Innate Lymphoid Cells Type 2 in Patients with Common Variable Immunodeficiency with Secondary Complications Is Part of a Broader Immune Dysregulation

Friedmann, D., Keller, B., Harder, I., Schupp, J. C., Tanriver, Y., Unger, S., & Warnatz, K. (2017) · Journal of Clinical Immunology · doi:10.1007/s10875-017-0444-0 · Cited by 7

Increased Serum Levels of soluble ST2 as a Predictor of Disease Progression in Systemic Sclerosis

Günther, F., Straub, R. H., HARTUNG, W. M., Luchner, A., Fleck, M., & Ehrenstein, B. P. (2021) · Scandinavian Journal of Rheumatology · doi:10.1080/03009742.2021.1929457 · Cited by 7

Editorial: Macrophages Role in Integrating Tissue Signals and Biological Processes in Chronic Inflammation and Fibrosis

Braga, T. T., Moura, I. C., Lepique, A. P., & Câmara, N. O. S. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00845 · Cited by 6

Research progress on pathogenesis of skin pigmentation in chronic liver disease

Liu, T., Xi, T., Dong, X., & Xu, D. (2024) · Biomolecules and Biomedicine · doi:10.17305/bb.2024.11085 · Cited by 6

IL-1b-Bearing NETs: Bridging Inflammation to Early Cirrhosis in Hepatitis B

Ntinopoulou, M., Konstantinidis, T. G., Chalkidou, A., Papagianni, E., Skeva, A., Panopoulou, M. I., & Chrysanthopoulou, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26125733 · Cited by 8

Dietary glycemic and energy load differentially modulates Schistosoma mansoni-induced granulomatous inflammation and response to antiparasitic chemotherapy

dos Reis, L. F. C., Cerdeira, C. D., Silva, L. C. C., Ramos, A. B. D. S. B., Silva, J. E. C., Castro, A. P., Ventura, R. R., Souza, R. L. M., Marques, M. J., & Novaes, R. D. (2024) · Acta Tropica · doi:10.1016/j.actatropica.2024.107141 · Cited by 6

CD44, IL-33, and ST2 Gene Polymorphisms on Hepatocellular Carcinoma Susceptibility in the Chinese Population

Pan, X., Li, M., Huang, L., Mo, D., Liang, Y., Huang, Z., Zhu, B., & Fang, M. (2020) · BioMed Research International · doi:10.1155/2020/2918517 · Cited by 6

A single-cell view of biliary atresia

Russi, A. E., & Bezerra, J. A. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-021-00417-5 · Cited by 6

ILCs in liver pathology

Visan, I. (2013) · Nature Immunology · doi:10.1038/ni.2717

Interleukin-33 in the pathogenesis of liver fibrosis: alarming ILC2 and hepatic stellate cells

Weiskirchen, R., & Tacke, F. (2016) · Cellular and Molecular Immunology · doi:10.1038/cmi.2016.62 · Cited by 46

Interleukin-33 overexpression is associated with liver fibrosis in mice and humans

Marvie, P., Lisbonne, M., L’Helgoualc’h, A., Rauch, M., Turlin, B., Preisser, L., Bourd‐Boittin, K., Théret, N., Gascan, H., Piquet‐Pellorce, C., et al. (2010) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00801.x · Cited by 251

Group 2 innate lymphoid cells exhibit progressively higher levels of activation during worsening of liver fibrosis

Gonzalez-Polo, V., Molineris, M. P., Cervera, V., Gambaro, S. E., Yantorno, S. E., Descalzi, V., Tiribelli, C., Gondolesi, G. E., & Meier, D. (2019) · Annals of Hepatology · doi:10.1016/j.aohep.2018.12.001 · Cited by 39

Interleukin-33 drives hepatic fibrosis through activation of hepatic stellate cells

Tan, Z., Liu, Q., Jiang, R., Lv, L., Shoto, S. S., Maillet, I., Quesniaux, V. F. J., Tang, J., Zhang, W., Sun, B., et al. (2017) · Cellular and Molecular Immunology · doi:10.1038/cmi.2016.63 · Cited by 122