Neurath, Markus F.

Cytokines in inflammatory bowel disease

Neurath, M. F. (2014) · Nature Reviews Immunology

Inflammatory Bowel DiseaseOcular Diseases and Behçet’s Syndrome

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Chemically induced mouse models of acute and chronic intestinal inflammation

Wirtz, S., Popp, V., Kindermann, M., Gerlach, K., Weigmann, B., Fichtner-Feigl, S., & Neurath, M. F. (2017) · Nature Protocols

Inflammatory Bowel DiseaseOcular Diseases and Behçet’s Syndrome

Cited by 1,575

Chemically induced mouse models of intestinal inflammation

Wirtz, S., Neufert, C., Weigmann, B., & Neurath, M. F. (2007) · Nature Protocols

Inflammatory Bowel DiseaseOcular Diseases and Behçet’s Syndrome

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Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn disease and experimental colitis in vivo

Atreya, R., Mudter, J., Finotto, S., Müllberg, J., Jostock, T., Wirtz, S., Schütz, M., Bartsch, B., Holtmann, M., Becker, C., et al. (2000) · Nature Medicine

Inflammatory Bowel DiseaseCytokine Signaling Pathways and Interactions

Cited by 1,293

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

Shen, P., Roch, T., Lampropoulou, V., O’Connor, R. A., Stervbo, U., Hilgenberg, E., Ries, S., Dang, V. D., Jaimes, Y., Daridon, C., et al. (2014) · Nature

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 1,048

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

Pickert, G., Neufert, C., Leppkes, M., Zheng, Y., Wittkopf, N., Warntjen, M., Lehr, H.-A., Hirth, S., Weigmann, B., Wirtz, S., et al. (2009) · Journal of Experimental Medicine

Cytokine Signaling Pathways and InteractionsInflammatory Bowel Disease

Cited by 1,043

Environmental triggers in IBD: a review of progress and evidence

Ananthakrishnan, A. N., Bernstein, C. N., Iliopoulos, D., Macpherson, A., Neurath, M. F., Ali, R. A. R., Vavricka, S. R., & Fiocchi, C. (2018) · Nature Reviews Gastroenterology & Hepatology

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 948

CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes

Tiede, I., Fritz, G., Strand, S., Poppe, D., Dvorsky, R., Strand, D., Lehr, H. A., Wirtz, S., Becker, C., Atreya, R., et al. (2003) · Journal of Clinical Investigation

Protein Kinase Regulation and GTPase SignalingCell death mechanisms and regulation

Cited by 828

TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling

Becker, C., Fantini, M. C., Schramm, C., Lehr, H. A., Wirtz, S., Nikolaev, A., Burg, J., Strand, S., Kiesslich, R., Huber, S., et al. (2004) · Immunity

TGF-β signaling in diseasesCytokine Signaling Pathways and Interactions

Cited by 726

Mend Your Fences

Martini, E., Krug, S. M., Siegmund, B., Neurath, M. F., & Becker, C. (2017) · Cellular and Molecular Gastroenterology and Hepatology

Inflammatory Bowel DiseaseGut microbiota and health

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Interleukin-33-Dependent Innate Lymphoid Cells Mediate Hepatic Fibrosis

Mchedlidze, T., Waldner, M., Zopf, S., Walker, J., Rankin, A. L., Schuchmann, M., Voehringer, D., McKenzie, A. N. J., Neurath, M. F., Pflanz, S., et al. (2013) · Immunity

IL-33, ST2, and ILC PathwaysLiver physiology and pathology

Cited by 502

Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium

Günther, C., Neumann, H., Neurath, M. F., & Becker, C. (2013) · Gut

Cell death mechanisms and regulationInflammatory Bowel Disease

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Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study

Feagan, B. G., Sandborn, W. J., D'Haens, G., Panés, J., Kaser, A., Ferrante, M., Louis, E., Franchimont, D., Dewit, O., Seidler, U., et al. (2017) · The Lancet

Inflammatory Bowel DiseasePsoriasis: Treatment and Pathogenesis

Cited by 451

TH9 cells that express the transcription factor PU.1 drive T cell–mediated colitis via IL-9 receptor signaling in intestinal epithelial cells

Gerlach, K., Hwang, Y., Nikolaev, A., Atreya, R., Dornhoff, H., Steiner, S., Lehr, H.-A., Wirtz, S., Vieth, M., Waisman, A., et al. (2014) · Nature Immunology

Inflammatory Bowel DiseaseT-cell and B-cell Immunology

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How Cytokine Networks Fuel Inflammation: Toward a cytokine-based disease taxonomy

Schett, G., Elewaut, D., McInnes, I. B., Dayer, J.-M., & Neurath, M. F. (2013) · Nature Medicine

Cytokine Signaling Pathways and InteractionsPsoriasis: Treatment and Pathogenesis

Cited by 406

In vivo imaging using fluorescent antibodies to tumor necrosis factor predicts therapeutic response in Crohn's disease

Atreya, R., Neumann, H., Neufert, C., Waldner, M. J., Billmeier, U., Zopf, Y., Willma, M., App, C., Münster, T., Kessler, H., et al. (2014) · Nature Medicine

Inflammatory Bowel DiseaseRheumatoid Arthritis Research and Therapies

Cited by 392

High resolution colonoscopy in live mice

Becker, C., Fantini, M. C., & Neurath, M. F. (2006) · Nature Protocols

Inflammatory Bowel DiseaseColorectal Cancer Screening and Detection

Cited by 369

Involvement of IL–6 in the pathogenesis of inflammatory bowel disease and colon cancer

Atreya, R., & Neurath, M. F. (2005) · Clinical Reviews in Allergy & Immunology

Inflammatory Bowel DiseaseCytokine Signaling Pathways and Interactions

Cited by 324

Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors

Schwitalla, S., Ziegler, P. K., Horst, D., Becker, V., Kerle, I., Begus-Nahrmann, Y., Lechel, A., Rudolph, K. L., Langer, R., Slotta-Huspenina, J., et al. (2013) · Cancer Cell

Cancer-related Molecular PathwaysGenetic factors in colorectal cancer

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Neutrophil Extracellular Traps Initiate Gallstone Formation

Muñoz, L. E., Boeltz, S., Bilyy, R., Schauer, C., Mahajan, A., Widulin, N., Grüneboom, A., Herrmann, I., Boada, E., Rauh, M., et al. (2019) · Immunity

Neutrophil, Myeloperoxidase and Oxidative MechanismsGallbladder and Bile Duct Disorders

Cited by 192

The intestinal microbiota in inflammatory bowel disease

Becker, C., Neurath, M. F., & Wirtz, S. (2015) · ILAR Journal

Gut microbiota and healthInflammatory Bowel Disease

Cited by 185

Gut–Liver Axis: How Do Gut Bacteria Influence the Liver?

Konturek, P. C., Harsch, I. A., Konturek, K., Schink, M., Konturek, T., Neurath, M. F., & Zopf, Y. (2018) · Medical Sciences

Gut microbiota and healthLiver Disease and Transplantation

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The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis

Günther, C., He, G.-W., Kremer, A. E., Murphy, J. M., Petrie, E. J., Amann, K., Vandenabeele, P., Linkermann, A., Poremba, C., Schleicher, U., et al. (2016) · Journal of Clinical Investigation

Cell death mechanisms and regulationLiver Diseases and Immunity

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Organoids in gastrointestinal diseases: From experimental models to clinical translation

Günther, C., Winner, B., Neurath, M. F., & Stappenbeck, T. S. (2022) · Gut

3D Printing in Biomedical ResearchCancer Cells and Metastasis

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