McKenzie, Andrew N.J.

Innate lymphoid cells: A new paradigm in immunology

Eberl, G., Colonna, M., Di Santo, J. P., & McKenzie, A. N. J. (2015) · Science

IL-33, ST2, and ILC PathwaysT-cell and B-cell Immunology

Cited by 878

IL-33–Responsive Lineage−CD25+CD44hi Lymphoid Cells Mediate Innate Type 2 Immunity and Allergic Inflammation in the Lungs

Bartemes, K. R., Iijima, K., Kobayashi, T., Kephart, G. M., McKenzie, A. N., & Kita, H. (2012) · The Journal of Immunology

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 549

Interleukin-33-Dependent Innate Lymphoid Cells Mediate Hepatic Fibrosis

Mchedlidze, T., Waldner, M., Zopf, S., Walker, J., Rankin, A. L., Schuchmann, M., Voehringer, D., McKenzie, A. N. J., Neurath, M. F., Pflanz, S., et al. (2013) · Immunity

IL-33, ST2, and ILC PathwaysLiver physiology and pathology

Cited by 502

TH9 cells that express the transcription factor PU.1 drive T cell–mediated colitis via IL-9 receptor signaling in intestinal epithelial cells

Gerlach, K., Hwang, Y., Nikolaev, A., Atreya, R., Dornhoff, H., Steiner, S., Lehr, H.-A., Wirtz, S., Vieth, M., Waisman, A., et al. (2014) · Nature Immunology

Inflammatory Bowel DiseaseT-cell and B-cell Immunology

Cited by 407

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis

Hams, E., Armstrong, M. E., Barlow, J. L., Saunders, S. P., Schwartz, C., Cooke, G., Fahy, R. J., Crotty, T. B., Hirani, N., Flynn, R. J., et al. (2014) · Proceedings of the National Academy of Sciences

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisIL-33, ST2, and ILC Pathways

Cited by 376

The deubiquitinase OTULIN is an essential negative regulator of inflammation and autoimmunity

Damgaard, R. B., Walker, J. A., Marco-Casanova, P., Morgan, N. V., Titheradge, H. L., Elliott, P. R., McHale, D., Maher, E. R., McKenzie, A. N. J., & Komander, D. (2016) · Cell

NF-κB Signaling PathwaysUbiquitin and proteasome pathways

Cited by 348

Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation

Beale, J., Jayaraman, A., Jackson, D. J., Macintyre, J. D. R., Edwards, M. R., Walton, R. P., Zhu, J., Ching, Y. M., Shamji, B., Edwards, M., et al. (2014) · Science Translational Medicine

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 332

IL-9-Deficient Mice Establish Fundamental Roles for IL-9 in Pulmonary Mastocytosis and Goblet Cell Hyperplasia but Not T Cell Development

Townsend, M. J., Fallon, P. G., Matthews, D. J., Smith, P., Jolin, H. E., & McKenzie, A. N. J. (2000) · Immunity

Asthma and respiratory diseasesMast cells and histamine

Cited by 328

Single-cell RNA-seq identifies a PD-1hi ILC progenitor and defines its development pathway

Yu, Y., Tsang, J. C. H., Wang, C., Clare, S., Wang, J., Chen, X., Brandt, C., Kane, L., Campos, L. S., Lu, L., et al. (2016) · Nature

IL-33, ST2, and ILC PathwaysT-cell and B-cell Immunology

Cited by 306

IL-9– and mast cell–mediated intestinal permeability predisposes to oral antigen hypersensitivity

Forbes, E. E., Groschwitz, K., Abonia, J. P., Brandt, E. B., Cohen, E., Blanchard, C., Ahrens, R., Seidu, L., McKenzie, A., Strait, R., et al. (2008) · The Journal of Experimental Medicine

Food Allergy and Anaphylaxis ResearchMast cells and histamine

Cited by 295

An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers

Morita, H., Arae, K., Unno, H., Miyauchi, K., Toyama, S., Nambu, A., Oboki, K., Ohno, T., Motomura, K., Matsuda, A., et al. (2015) · Immunity

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 274

Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and γδ T cells

Van Dyken, S. J., Mohapatra, A., Nussbaum, J. C., Molofsky, A. B., Thornton, E. E., Ziegler, S. F., McKenzie, A. N. J., Krummel, M. F., Liang, H.-E., & Locksley, R. M. (2014) · Immunity

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 251

Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy

McSorley, H. J., Blair, N. F., Smith, K. A., McKenzie, A. N. J., & Maizels, R. M. (2014) · Mucosal Immunology

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 163

Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity

Saunders, S. P., Moran, T., Floudas, A., Wurlod, F., Kaszlikowska, A., Salimi, M., Quinn, E. M., Oliphant, C. J., Núñez, G., McManus, R., et al. (2016) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 160

Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity

Smith, P., Fallon, R. E., Mangan, N. E., Walsh, C. M., Saraiva, M., Sayers, J. R., McKenzie, A. N. J., Alcami, A., & Fallon, P. G. (2005) · The Journal of Experimental Medicine

Parasites and Host InteractionsParasitic Diseases Research and Treatment

Cited by 160

The Absence of Interleukin 9 Does Not Affect the Development of Allergen-induced Pulmonary Inflammation nor Airway Hyperreactivity

McMillan, S. J., Bishop, B., Townsend, M. J., McKenzie, A. N., & Lloyd, C. M. (2002) · The Journal of Experimental Medicine

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 142

IL-9 Promotes IL-13-Dependent Paneth Cell Hyperplasia and Up-Regulation of Innate Immunity Mediators in Intestinal Mucosa

Steenwinckel, V., Louahed, J., Lemaire, M. M., Sommereyns, C., Warnier, G., McKenzie, A., Brombacher, F., Van Snick, J., & Renauld, J.-C. (2009) · The Journal of Immunology

IL-33, ST2, and ILC PathwaysInflammatory Bowel Disease

Cited by 109

IL-13 Mediates In Vivo IL-9 Activities on Lung Epithelial Cells but Not on Hematopoietic Cells

Steenwinckel, V., Louahed, J., Orabona, C., Huaux, F., Warnier, G., McKenzie, A., Lison, D., Levitt, R., & Renauld, J.-C. (2007) · The Journal of Immunology

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 108

IL-9 regulates intestinal barrier function in experimental T cell-mediated colitis

Gerlach, K., McKenzie, A. N., Neurath, M. F., & Weigmann, B. (2015) · Tissue Barriers

Inflammatory Bowel DiseaseBarrier Structure and Function Studies

Cited by 83

PU.1-driven Th9 Cells Promote Colorectal Cancer in Experimental Colitis Models Through Il-6 Effects in Intestinal Epithelial Cells

Gerlach, K., Popp, V., Wirtz, S., Al-Saifi, R., Gonzalez Acera, M., Atreya, R., Dregelies, T., Vieth, M., Fichtner-Feigl, S., McKenzie, A. N. J., et al. (2022) · Journal of Crohn's and Colitis

T-cell and B-cell ImmunologyIL-33, ST2, and ILC Pathways

Cited by 25

Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation

Ferreira, A. C. F., Szeto, A. C. H., Clark, P. A., Crisp, A., Kozik, P., Jolin, H. E., & McKenzie, A. N. J. (2023) · Immunity

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 23