The DOI matches its Crossref record; 182 of the 182 references it cites were found in a registry or an index.
Plasmacytoid Dendritic Cells: Development, Regulation, and Function
Open accessAbstract
Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-derived nucleic acids and respond with rapid and massive production of type I interferon. This review summarizes our current understanding of pDC biology, including transcriptional regulation, heterogeneity, role in antiviral immune responses, and involvement in immune pathology, particularly in autoimmune diseases, immunodeficiency and cancer. We also highlight the remaining gaps in our knowledge and important questions for the field, such as the molecular basis of unique interferon-producing capacity of pDCs. A better understanding of cell type-specific positive and negative control of pDC function should pave the way for translational applications focused on this immune cell type.
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Decoding Toll-like receptors: Recent insights and perspectives in innate immunity
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Metadata
- Authors
- Reizis, B.
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2019-01
- Volume
- 50
- Issue
- 1
- Pages
- 37-50
- ISSN
- 1074-7613 (ISSN-L)
- OpenAlex
- W2908943028
- Cited by
- 673
- References
- 182
- FWCI
- 21.79
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
