Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury
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Clec2d was enriched in both early and late pre-MGnD clusters.
“Moreover, C-Type Lectin-Receptor-2d (Clec2d), which has been shown to recognize histones released upon necrotic cell death and to mediate inflammation 36 , was enriched in both early and late pre-MGnD clusters.”
From Identification of a protective microglial state mediated by miR-155 and interferon-γ signaling in a mouse model of Alzheimer’s disease (2023) · cites this paper as [36]
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- Authors
- Lai, J.-J., Cruz, F. M., & Rock, K. L.
- Venue
- Immunity
- Publisher
- Elsevier BV
- Published
- 2020-01
- Volume
- 52
- Issue
- 1
- Pages
- 123-135.e6
- ISSN
- 1074-7613
- PMC
- PMC6962543
- Cited by
- 84
- References
- 10
- Language
- en
- Licence
- Funders
- National Institutes of Health
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