Epigenetic regulation: A new frontier for biomedical engineers

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Fire, A., Xu, S., Montgomery, M. K., Kostas, S. A., Driver, S. E., & Mello, C. C. (1998) · Nature · doi:10.1038/35888 · Cited by 15,429 · see citing works

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

WATSON, J. D., & CRICK, F. H. C. (1953) · Nature · doi:10.1038/171737a0 · Cited by 13,584 · see citing works

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Lee, R. C., Feinbaum, R. L., & Ambros, V. (1993) · Cell · doi:10.1016/0092-8674(93)90529-y · Cited by 12,948 · see citing works

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

Lieberman-Aiden, E., van Berkum, N. L., Williams, L., Imakaev, M., Ragoczy, T., Telling, A., Amit, I., Lajoie, B. R., Sabo, P. J., Dorschner, M. O., et al. (2009) · Science · doi:10.1126/science.1181369 · Cited by 8,898 · see citing works

Circular RNAs are a large class of animal RNAs with regulatory potency

Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature · doi:10.1038/nature11928 · Cited by 7,990 · see citing works

Natural RNA circles function as efficient microRNA sponges

Hansen, T. B., Jensen, T. I., Clausen, B. H., Bramsen, J. B., Finsen, B., Damgaard, C. K., & Kjems, J. (2013) · Nature · doi:10.1038/nature11993 · Cited by 7,985 · see citing works

High-Resolution Profiling of Histone Methylations in the Human Genome

Barski, A., Cuddapah, S., Cui, K., Roh, T.-Y., Schones, D. E., Wang, Z., Wei, G., Chepelev, I., & Zhao, K. (2007) · Cell · doi:10.1016/j.cell.2007.05.009 · Cited by 6,845 · see citing works

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

Buenrostro, J. D., Giresi, P. G., Zaba, L. C., Chang, H. Y., & Greenleaf, W. J. (2013) · Nature Methods · doi:10.1038/nmeth.2688 · Cited by 6,422 · see citing works

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Okano, M., Bell, D. W., Haber, D. A., & Li, E. (1999) · Cell · doi:10.1016/s0092-8674(00)81656-6 · Cited by 6,143 · see citing works

Regulation of chromatin by histone modifications

Bannister, A. J., & Kouzarides, T. (2011) · Cell Research · doi:10.1038/cr.2011.22 · Cited by 6,012 · see citing works

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

Herman, J. G., Graff, J. R., Myöhänen, S., Nelkin, B. D., & Baylin, S. B. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.18.9821 · Cited by 5,610 · see citing works

Landscape of transcription in human cells

Djebali, S., Davis, C. A., Merkel, A., Dobin, A., Lassmann, T., Mortazavi, A., Tanzer, A., Lagarde, J., Lin, W., Schlesinger, F., et al. (2012) · Nature · doi:10.1038/nature11233 · Cited by 5,187 · see citing works

Origins and Mechanisms of miRNAs and siRNAs

Carthew, R. W., & Sontheimer, E. J. (2009) · Cell · doi:10.1016/j.cell.2009.01.035 · Cited by 5,023 · see citing works

Molecular Mechanisms of Long Noncoding RNAs

Wang, K., & Chang, H. Y. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.08.018 · Cited by 4,390 · see citing works

Capturing Chromosome Conformation

Dekker, J., Rippe, K., Dekker, M., & Kleckner, N. (2002) · Science · doi:10.1126/science.1067799 · Cited by 3,652 · see citing works

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

Ito, S., Shen, L., Dai, Q., Wu, S. C., Collins, L. B., Swenberg, J. A., He, C., & Zhang, Y. (2011) · Science · doi:10.1126/science.1210597 · Cited by 3,451 · see citing works

Central Dogma of Molecular Biology

CRICK, F. (1970) · Nature · doi:10.1038/227561a0 · Cited by 3,444 · see citing works

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

Frommer, M., McDonald, L. E., Millar, D. S., Collis, C. M., Watt, F., Grigg, G. W., Molloy, P. L., & Paul, C. L. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.5.1827 · Cited by 3,238 · see citing works

CRISPR-Cas systems for editing, regulating and targeting genomes

Sander, J. D., & Joung, J. K. (2014) · Nature Biotechnology · doi:10.1038/nbt.2842 · Cited by 3,153 · see citing works

A Species of Small Antisense RNA in Posttranscriptional Gene Silencing in Plants

Hamilton, A. J., & Baulcombe, D. C. (1999) · Science · doi:10.1126/science.286.5441.950 · Cited by 3,048 · see citing works

Widespread transcription at neuronal activity-regulated enhancers

Kim, T.-K., Hemberg, M., Gray, J. M., Costa, A. M., Bear, D. M., Wu, J., Harmin, D. A., Laptewicz, M., Barbara-Haley, K., Kuersten, S., et al. (2010) · Nature · doi:10.1038/nature09033 · Cited by 2,450 · see citing works

The ENCODE (ENCyclopedia Of DNA Elements) Project

(2004) · Science · doi:10.1126/science.1105136 · Cited by 2,390 · see citing works

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

Chiu, J.-J., & Chien, S. (2011) · Physiological Reviews · doi:10.1152/physrev.00047.2009 · Cited by 2,280 · see citing works

ChIP–seq: advantages and challenges of a maturing technology

Park, P. J. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2641 · Cited by 2,217 · see citing works

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

Huarte, M., Guttman, M., Feldser, D., Garber, M., Koziol, M. J., Kenzelmann-Broz, D., Khalil, A. M., Zuk, O., Amit, I., Rabani, M., et al. (2010) · Cell · doi:10.1016/j.cell.2010.06.040 · Cited by 2,053 · see citing works

Mediator and cohesin connect gene expression and chromatin architecture

Kagey, M. H., Newman, J. J., Bilodeau, S., Zhan, Y., Orlando, D. A., van Berkum, N. L., Ebmeier, C. C., Goossens, J., Rahl, P. B., Levine, S. S., et al. (2010) · Nature · doi:10.1038/nature09380 · Cited by 1,939 · see citing works

Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

Weber, M., Davies, J. J., Wittig, D., Oakeley, E., Haase, M., Lam, W., & Schübeler, D. (2005) · Nature Genetics · doi:10.1038/ng1598 · Cited by 1,885 · see citing works

lincRNAs act in the circuitry controlling pluripotency and differentiation

Guttman, M., Donaghey, J., Carey, B. W., Garber, M. G., Grenier, J. K., Munson, G., Young, G., Lucas, A. B., Ach, R. A., Bruhn, L., et al. (2011) · Nature · doi:10.1038/nature10398 · Cited by 1,845 · see citing works

Nanoparticle biointerfacing by platelet membrane cloaking

Hu, C. J., Fang, R. H., Wang, K.-C., Luk, B. T., Thamphiwatana, S., Dehaini, D., Nguyen, P., Angsantikul, P., Wen, C. H., Kroll, A. V., et al. (2015) · Nature · doi:10.1038/nature15373 · Cited by 1,795 · see citing works

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

Bell, A. C., & Felsenfeld, G. (2000) · Nature · doi:10.1038/35013100 · Cited by 1,746 · see citing works

An oestrogen-receptor-α-bound human chromatin interactome

Fullwood, M. J., Liu, M. H., Pan, Y. F., Liu, J., Han, X., Mohamed, Y. B., Orlov, Y. L., Velkov, S., Ho, A., Poh, H. M., et al. (2009) · Nature · doi:10.1038/nature08497 · Cited by 1,728 · see citing works

Expanded identification and characterization of mammalian circular RNAs

Guo, J. U., Agarwal, V., Guo, H., & Bartel, D. P. (2014) · Genome biology · doi:10.1186/s13059-014-0409-z · Cited by 1,578 · see citing works

Principles and challenges of genome-wide DNA methylation analysis

Laird, P. W. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2732 · Cited by 1,574 · see citing works

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

Falkenberg, K. J., & Johnstone, R. W. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4360 · Cited by 1,564 · see citing works

5-Azacytidine and 5-aza-2′-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

Christman, J. K. (2002) · Oncogene · doi:10.1038/sj.onc.1205699 · Cited by 1,532 · see citing works

Role of Endothelial Shear Stress in the Natural History of Coronary Atherosclerosis and Vascular Remodeling

Chatzizisis, Y. S., Coskun, A. U., Jonas, M., Edelman, E. R., Feldman, C. L., & Stone, P. H. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.02.059 · Cited by 1,483 · see citing works

Nanoparticles as drug delivery systems

Wilczewska, A. Z., Niemirowicz, K., Markiewicz, K. H., & Car, H. (2012) · Pharmacological Reports · doi:10.1016/s1734-1140(12)70901-5 · Cited by 1,445 · see citing works

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

Yap, K. L., Li, S., Muñoz-Cabello, A. M., Raguz, S., Zeng, L., Mujtaba, S., Gil, J., Walsh, M. J., & Zhou, M.-M. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.03.021 · Cited by 1,391 · see citing works

X inactivation, differentiation, and DNA methylation

Riggs, A. D. (2008) · Cytogenetics and Cell Genetics · doi:10.1159/000130315 · Cited by 1,343 · see citing works

Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions

Chu, C., Qu, K., Zhong, F. L., Artandi, S. E., & Chang, H. Y. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.08.027 · Cited by 1,274 · see citing works

Epigenetic Regulation by Long Noncoding RNAs

Lee, J. T. (2012) · Science · doi:10.1126/science.1231776 · Cited by 1,258 · see citing works

How Are Alkynes Scrambled?

Bunz, U. H. F. (2005) · Science · doi:10.1126/science.1111098 · Cited by 1,252 · see citing works

Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis

Meissner, A. (2005) · Nucleic Acids Research · doi:10.1093/nar/gki901 · Cited by 1,203 · see citing works

Cohesin mediates transcriptional insulation by CCCTC-binding factor

Wendt, K. S., Yoshida, K., Itoh, T., Bando, M., Koch, B., Schirghuber, E., Tsutsumi, S., Nagae, G., Ishihara, K., Mishiro, T., et al. (2008) · Nature · doi:10.1038/nature06634 · Cited by 1,193 · see citing works

Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elementsPreprint

Dostie, J., Richmond, T., Arnaout, R., Selzer, R. R., Lee, W. L., Honan, T., Rubio, E. D., Krumm, A., Lamb, J., Nusbaum, C., et al. (2006) · Genome Research · doi:10.1101/gr.5571506 · Cited by 1,182 · see citing works

ALTERATION OF NUCLEOSOME STRUCTURE AS A MECHANISM OF TRANSCRIPTIONAL REGULATION

Workman, J. L., & Kingston, R. E. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.545 · Cited by 1,129 · see citing works

CLIP Identifies Nova-Regulated RNA Networks in the Brain

Ule, J., Jensen, K. B., Ruggiu, M., Mele, A., Ule, A., & Darnell, R. B. (2003) · Science · doi:10.1126/science.1090095 · Cited by 1,120 · see citing works

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

Bell, A. C., West, A. G., & Felsenfeld, G. (1999) · Cell · doi:10.1016/s0092-8674(00)81967-4 · Cited by 1,101 · see citing works

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

Wu, H., & Zhang, Y. (2014) · Cell · doi:10.1016/j.cell.2013.12.019 · Cited by 1,065 · see citing works

Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation

Li, W., Notani, D., Ma, Q., Tanasa, B., Nunez, E., Chen, A. Y., Merkurjev, D., Zhang, J., Ohgi, K., Song, X., et al. (2013) · Nature · doi:10.1038/nature12210 · Cited by 1,049 · see citing works

Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells

Ehrlich, M., Gama-Sosa, M. A., Huang, L.-H., Midgett, R. M., Kuo, K. C., McCune, R. A., & Gehrke, C. W. (1982) · Nucleic Acids Research · doi:10.1093/nar/10.8.2709 · Cited by 1,039 · see citing works

A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements

Yang, A. S. (2004) · Nucleic Acids Research · doi:10.1093/nar/gnh032 · Cited by 1,033 · see citing works

FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatinPreprint

Giresi, P. G., Kim, J., McDaniell, R. M., Iyer, V. R., & Lieb, J. D. (2006) · Genome Research · doi:10.17615/8cez-3e87 · Cited by 949 · see citing works

A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

De Santa, F., Barozzi, I., Mietton, F., Ghisletti, S., Polletti, S., Tusi, B. K., Muller, H., Ragoussis, J., Wei, C.-L., & Natoli, G. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000384 · Cited by 934 · see citing works

Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment

Klattenhoff, C., Scheuermann, J. C., Surface, L. E., Bradley, R. K., Fields, P., Steinhauser, M. L., Ding, H., Butty, V. L., Sosa, L. T., Haas, S. F., et al. (2013) · Cell · doi:10.1016/j.cell.2013.01.003 · Cited by 910 · see citing works

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

Ehrich, M., Nelson, M. R., Stanssens, P. E., Zabeau, M., Liloglou, T., Xinarianos, G., Cantor, C. R., Field, J. K., & van den Boom, D. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507816102 · Cited by 812 · see citing works

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4

Gilchrist, M., Thorsson, V., Li, B., Rust, A., Korb, M., Kennedy, K. A., Hai, T., Bolouri, H., & Aderem, A. (2006) · Nature · doi:10.1038/nature04768 · Cited by 782 · see citing works

PIWI-Interacting RNA: Its Biogenesis and Functions

Iwasaki, Y. W., Siomi, M. C., & Siomi, H. (2015) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060614-034258 · Cited by 765 · see citing works

Comprehensive Genome-wide Protein-DNA Interactions Detected at Single-Nucleotide Resolution

Rhee, H. S., & Pugh, B. F. (2011) · Cell · doi:10.1016/j.cell.2011.11.013 · Cited by 760 · see citing works

Long Noncoding RNAs in Cardiovascular Diseases

Uchida, S., & Dimmeler, S. (2015) · Circulation Research · doi:10.1161/circresaha.116.302521 · Cited by 739 · see citing works

New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?

Luger, K., Dechassa, M. L., & Tremethick, D. J. (2012) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3382 · Cited by 738 · see citing works

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

Harris, R. A., Wang, T., Coarfa, C., Nagarajan, R. P., Hong, C., Downey, S. L., Johnson, B., Fouse, S. D., Delaney, A. D., Zhao, Y., et al. (2010) · Nature Biotechnology · doi:10.1038/nbt.1682 · Cited by 713 · see citing works

Rapid spontaneous accessibility of nucleosomal DNA

Gu, L.-Q., Levitus, M., Bustamante, C., & Widom, J. (2005) · Nature Structural &Molecular Biology · doi:10.1038/nsmb869 · Cited by 692 · see citing works

Determinants of nucleosome positioning

Struhl, K., & Segal, E. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2506 · Cited by 685 · see citing works

Circulating Long Noncoding RNA, LIPCAR, Predicts Survival in Patients With Heart Failure

Kumarswamy, R., Bauters, C., Volkmann, I. R., Maury, F., Fetisch, J., Holzmann, A., Lemesle, G., de Groote, P., Pinet, F., & Thum, T. (2014) · Circulation Research · doi:10.1161/circresaha.114.303915 · Cited by 627 · see citing works

Cryo-EM Study of the Chromatin Fiber Reveals a Double Helix Twisted by Tetranucleosomal Units

Song, F., Chen, P., Sun, D., Wang, M., Dong, L., Liang, D., Xu, R.-M., Zhu, P., & Li, G. (2014) · Science · doi:10.1126/science.1251413 · Cited by 617 · see citing works

NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis

Brown, J. D., Lin, C. Y., Duan, Q., Griffin, G., Federation, A. J., Paranal, R. M., Bair, S., Newton, G., Lichtman, A. H., Kung, A. L., et al. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.08.024 · Cited by 614 · see citing works

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

Harismendy, O., Notani, D., Song, X., Rahim, N. G., Tanasă, B., Heintzman, N. D., Ren, B., Fu, X., Topol, E. J., Rosenfeld, M. G., et al. (2011) · Nature · doi:10.1038/nature09753 · Cited by 605 · see citing works

Prenatal Tobacco Smoke Exposure Affects Global and Gene-specific DNA Methylation

Breton, C. V., Byun, H., Wenten, M., Pan, F., Yang, A. S., & Gilliland, F. D. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200901-0135oc · Cited by 591 · see citing works

Chromatin remodelling: the industrial revolution of DNA around histones

Saha, A., Wittmeyer, J., & Cairns, B. R. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1945 · Cited by 590 · see citing works

lncRNAdb: a reference database for long noncoding RNAs

Amaral, P., Clark, M. B., Gascoigne, D. K., Dinger, M. E., & Mattick, J. S. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq1138 · Cited by 584 · see citing works

The Dnmt1 DNA-(cytosine-C5)-methyltransferase Methylates DNA Processively with High Preference for Hemimethylated Target Sites

Hermann, A., Goyal, R., & Jeltsch, A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m403427200 · Cited by 569 · see citing works

Global mapping of protein-DNA interactions in vivo by digital genomic footprinting

Hesselberth, J. R., Chen, X., Zhang, Z., Sabo, P. J., Sandstrom, R., Reynolds, A. P., Thurman, R. E., Neph, S., Kuehn, M. S., Noble, W. S., et al. (2009) · Nature Methods · doi:10.1038/nmeth.1313 · Cited by 559 · see citing works

Mapping Human Epigenomes

Rivera, C. M., & Ren, B. (2013) · Cell · doi:10.1016/j.cell.2013.09.011 · Cited by 550 · see citing works

lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs

Quek, X. C., Thomson, D. W., Mååg, J. L. V., Bartoniček, N., Signal, B., Clark, M. B., Gloss, B., & Dinger, M. E. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku988 · Cited by 529 · see citing works

Sensitive and quantitative universal Pyrosequencing™ methylation analysis of CpG sites

Colella, S., Shen, L., Baggerly, K., Issa, J. J., & Krahe, R. (2003) · BioTechniques · doi:10.2144/03351md01 · Cited by 514 · see citing works

LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis, and Atherosclerosis by Enhancing p53 Activity

Wu, G., Cai, J., Han, Y., Chen, J., Huang, Z., Chen, C., Cai, Y., Huang, H., Yang, Y., Liu, Y., et al. (2014) · Circulation · doi:10.1161/circulationaha.114.011675 · Cited by 486 · see citing works

Phase 1/2 study of the combination of 5-aza-2′-deoxycytidine with valproic acid in patients with leukemia

Garcia‐Manero, G., Kantarjian, H. M., Sánchez‐González, B., Yang, H., Rosner, G. L., Verstovšek, S., Rytting, M., Wierda, W. G., Ravandi, F., Koller, C. A., et al. (2006) · Blood · doi:10.1182/blood-2006-03-009142 · Cited by 466 · see citing works

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

Steenman, M., Rainier, S. R., Dobry, C. J., Grundy, P., Horon, I. L., & Feinberg, A. P. (1994) · Nature Genetics · doi:10.1038/ng0794-433 · Cited by 459 · see citing works

Deep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNAs in Failing Human Heart and Remodeling With Mechanical Circulatory Support

Yang, K., Yamada, K. A., Patel, A., Topkara, V. K., George, I., Cheema, F. H., Ewald, G. A., Mann, D. L., & Nerbonne, J. M. (2014) · Circulation · doi:10.1161/circulationaha.113.003863 · Cited by 453 · see citing works

ANRIL Expression Is Associated With Atherosclerosis Risk at Chromosome 9p21

Holdt, L. M., Beutner, F., Scholz, M. R., Gielen, S., Gäbel, G., Bergert, H., Schuler, G. C., Thiery, J., & Teupser, D. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.196832 · Cited by 452 · see citing works

Parental-origin-specific epigenetic modification of the mouse H19 gene

Ferguson‐Smith, A. C., Sasaki, H., Cattanach, B. M., & Surani, M. A. (1993) · Nature · doi:10.1038/362751a0 · Cited by 422 · see citing works

Functional implications of genome topology

Cavalli, G., & Misteli, T. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2474 · Cited by 415 · see citing works

Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk

Brinkman, A. B., Gu, H., Bartels, S. J. J., Zhang, Y., Matarese, F., Simmer, F., Marks, H., Bock, C., Gnirke, A., Meissner, A., et al. (2012) · Genome Research · doi:10.1101/gr.133728.111 · Cited by 413 · see citing works

Monoallelic expression of the human H19 gene

Zhang, Y., & Tycko, B. (1992) · Nature Genetics · doi:10.1038/ng0492-40 · Cited by 412 · see citing works

Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia

Trimarchi, T., Bilal, E., Ntziachristos, P., Fabbri, G., Dalla‐Favera, R., Tsirigos, A., & Aifantis, I. (2014) · Cell · doi:10.1016/j.cell.2014.05.049 · Cited by 412 · see citing works

Increased Homocysteine and S-Adenosylhomocysteine Concentrations and DNA Hypomethylation in Vascular Disease

Castro, R., Rivera, I. A., Struys, E. A., Jansen, E. E. W., Ravasco, P., Camilo, M., Blom, H. J., Jakobs, C., & de Almeida, I. T. (2003) · Clinical Chemistry · doi:10.1373/49.8.1292 · Cited by 409 · see citing works

Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes

Villeneuve, L. M., Reddy, M. A., Lanting, L. L., Wang, M., Li, M., & Natarajan, R. D. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803623105 · Cited by 408 · see citing works

Epigenetics and cardiovascular disease

Ordovás, J. M., & Smith, C. E. (2010) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2010.104 · Cited by 402 · see citing works

Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks

Holdt, L. M., Hoffmann, S., Sass, K., Langenberger, D., Scholz, M., Krohn, K., Finstermeier, K., Stahringer, A., Wilfert, W., Beutner, F., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003588 · Cited by 397 · see citing works

Localization of the X inactivation centre on the human X chromosome in Xq13

Brown, C. J., Lafrenière, R. G., Powers, V. E. C., Sebastio, G., Ballabio, A., Pettigrew, A. L., Ledbetter, D. H., Levy, E. R., Craig, I., & Willard, H. F. (1991) · Nature · doi:10.1038/349082a0 · Cited by 389 · see citing works

Robust 4C-seq data analysis to screen for regulatory DNA interactions

van de Werken, H. J. G., Landan, G., Holwerda, S. J. B., Hoichman, M., Klous, P., Chachik, R., Splinter, E., Valdes‐Quezada, C., Öz, Y., Bouwman, B. A. M., et al. (2012) · Nature Methods · doi:10.1038/nmeth.2173 · Cited by 376 · see citing works

Profiling genome-wide DNA methylation

Yong, W.-S., Hsu, F.-M., & Chen, P.-Y. (2016) · Epigenetics & Chromatin · doi:10.1186/s13072-016-0075-3 · Cited by 374 · see citing works

Inhibition of Histone Deacetylation Blocks Cardiac Hypertrophy Induced by Angiotensin II Infusion and Aortic Banding

Kee, H. J., Sohn, I. S., Nam, K. I., Park, J., Qian, Y., Yin, Z., Ahn, Y., Jeong, M., Bang, Y., Kim, N., et al. (2005) · Circulation · doi:10.1161/circulationaha.105.559724 · Cited by 368 · see citing works

An update on LNCipedia: a database for annotated human lncRNA sequences

Volders, P., Verheggen, K., Menschaert, G., Vandepoele, K., Martens, L., Vandesompele, J., & Mestdagh, P. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku1060 · Cited by 355 · see citing works

SUMO Promotes HDAC-Mediated Transcriptional Repression

Yang, S., & Sharrocks, A. D. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00060-7 · Cited by 351 · see citing works

DNA methylation of distal regulatory sites characterizes dysregulation of cancer genes

Aran, D., Sivan Sabato, A., & Hellman, A. (2013) · Genome biology · doi:10.1186/gb-2013-14-3-r21 · Cited by 335 · see citing works

Cardiac hypertrophy and histone deacetylase–dependent transcriptional repression mediated by the atypical homeodomain protein Hop

Kook, H., Lepore, J. J., Gitler, A. D., Lu, M. M., Yung, W. W.-M., Mackay, J. P., Zhou, R., Ferrari, V. A., Gruber, P. J., & Epstein, J. A. (2003) · Journal of Clinical Investigation · doi:10.1172/jci19137 · Cited by 332 · see citing works

Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B

Congrains, A., Kamide, K., Oguro, R., Yasuda, O., Miyata, K., Yamamoto, E., Kawai, T., Kusunoki, H., Yamamoto, H., Takeya, Y., et al. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.11.017 · Cited by 330 · see citing works

Identifying and mitigating bias in next-generation sequencing methods for chromatin biology

Meyer, C. A., & Liu, X. S. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3788 · Cited by 329 · see citing works

A Packing Mechanism for Nucleosome Organization Reconstituted Across a Eukaryotic Genome

Zhang, Z., Wippo, C. J., Wal, M., Ward, E., Korber, P., & Pugh, B. F. (2011) · Science · doi:10.1126/science.1200508 · Cited by 318 · see citing works

Epigenetic lesions at the H19 locus in Wilms' tumour patients

Moulton, T. A., Crenshaw, T., Hao, Y., Moosikasuwan, J., Lin, N., Dembitzer, F. R., Hensle, T., Weiss, L. M., McMorrow, L. E., Loew, T. H., et al. (1994) · Nature Genetics · doi:10.1038/ng0794-440 · Cited by 316 · see citing works

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2Preprint

Pasini, D., Hansen, K. H., Christensen, J. F., Agger, K., Cloos, P. A., & Helin, K. (2008) · Genes & Development · doi:10.1101/gad.470008 · Cited by 315 · see citing works

LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation.

Karimi, M., Johansson, S., Stach, D., Corcoran, M., Grandér, D., Schalling, M., Bakalkin, G., Lyko, F., Larsson, C., & Ekström, T. (2006) · Experimental Cell Research · doi:10.1016/j.yexcr.2006.03.006 · Cited by 311 · see citing works

Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis

Dunn, J., Qiu, H., Kim, S., Jjingo, D., Hoffman, R., Kim, C. W., Jang, I.-H., Son, D. J., Kim, D., Pan, C., et al. (2014) · Journal of Clinical Investigation · doi:10.1172/jci74792 · Cited by 308 · see citing works

Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation.

Wolf, S. F., Jolly, D. J., Lunnen, K. D., Friedmann, T., & Migeon, B. R. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.9.2806 · Cited by 298 · see citing works

Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA

Fatemi, M., Hermann, A., Gowher, H., & Jeltsch, A. (2002) · European Journal of Biochemistry · doi:10.1046/j.1432-1033.2002.03198.x · Cited by 285 · see citing works

The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA

Fatemi, M., Hermann, A., Pradhan, S., & Jeltsch, A. (2001) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.4709 · Cited by 275 · see citing works

Endocardial Brg1 Represses ADAMTS1 to Maintain the Microenvironment for Myocardial Morphogenesis

Stankunas, K., Hang, C. T., Tsun, Z.-Y., Chen, H., Lee, N. V., Wu, J. I., Shang, C., Bayle, J. H., Shou, W., Iruela‐Arispe, M. L., et al. (2008) · Developmental Cell · doi:10.1016/j.devcel.2007.11.018 · Cited by 262 · see citing works

Histone Deacetylase 1 Phosphorylation Promotes Enzymatic Activity and Complex Formation

Pflum, M. K. H., Tong, J. K., Lane, W. S., & Schreiber, S. L. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105590200 · Cited by 253 · see citing works

Xist has properties of the X-chromosome inactivation centre

Herzing, L. B. K., Romer, J. T., Horn, J. M., & Ashworth, A. (1997) · Nature · doi:10.1038/386272a0 · Cited by 253 · see citing works

Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes

Miao, F., Chen, Z., GENUTH, S. M., Paterson, A. D., Zhang, L., Wu, X., Li, S. M., Cleary, P. A., Riggs, A. D., Harlan, D. M., et al. (2014) · Diabetes · doi:10.2337/db13-1251 · Cited by 251 · see citing works

The Expression of Endothelial Nitric-oxide Synthase Is Controlled by a Cell-specific Histone Code

Fish, J. E., Matouk, C. C., Rachlis, A., Lin, S., Tai, S. C., D'Abreo, C., & Marsden, P. A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502115200 · Cited by 235 · see citing works

microRNA: A Master Regulator of Cellular Processes for Bioengineering Systems

Sun, W., Li, Y.-S. J., Huang, H., Shyy, J. Y.-J., & Chien, S. (2010) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-070909-105314 · Cited by 234 · see citing works

The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice

Zhang, Q.-J., Chen, H., Wang, L., Liu, D., Hill, J. A., & Liu, Z. (2011) · Journal of Clinical Investigation · doi:10.1172/jci46277 · Cited by 227 · see citing works

Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice

Zhou, G., Hamik, A., Nayak, L. V., Tian, H., Shi, H., Lu, Y., Sharma, N., Liao, X., Hale, A. T., Boerboom, L., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci66056 · Cited by 217 · see citing works

Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci

Jäger, R., Migliorini, G., Henrion, M., Kandaswamy, R., Speedy, H. E., Heindl, A., Whiffin, N., Carnicer, M. J., Broome, L. R., Dryden, N. H., et al. (2015) · Nature Communications · doi:10.1038/ncomms7178 · Cited by 210 · see citing works

Role of Nucleosomal Occupancy in the Epigenetic Silencing of the MLH1 CpG Island

Lin, J., Jeong, S., Liang, G., Takai, D., Fatemi, M., Tsai, Y., Egger, G., Gal‐Yam, E. N., & Jones, P. A. (2007) · Cancer Cell · doi:10.1016/j.ccr.2007.10.014 · Cited by 206 · see citing works

Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNAPreprint

Statham, A. L., Robinson, M. D., Song, J. Z., Coolen, M. W., Stirzaker, C., & Clark, S. J. (2012) · Genome Research · doi:10.1101/gr.132076.111 · Cited by 201 · see citing works

Hemodynamic Disturbed Flow Induces Differential DNA Methylation of Endothelial Kruppel-Like Factor 4 Promoter In Vitro and In Vivo

Jiang, Y., Jiménez, J. M., Ou, K., McCormick, M. E., Zhang, L.-D., & Davies, P. F. (2014) · Circulation Research · doi:10.1161/circresaha.115.303883 · Cited by 196 · see citing works

Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification

Quinn, J. J., Ilik, İ., Qu, K., Georgiev, P., Chu, C., Akhtar, A., & Chang, H. Y. (2014) · Nature Biotechnology · doi:10.1038/nbt.2943 · Cited by 177 · see citing works

Evaluation of a potential epigenetic biomarker by quantitative methyl‐single nucleotide polymorphism analysis

Uhlmann, K., Brinckmann, A., Toliat, M. R., Ritter, H., & Nürnberg, P. (2002) · Electrophoresis · doi:10.1002/elps.200290023 · Cited by 171 · see citing works

Genome‐wide histone methylation profile for heart failure

Kaneda, R., Takada, S., Yamashita, Y., Choi, Y. L., Nonaka‐Sarukawa, M., Soda, M., Misawa, Y., Isomura, T., Shimada, K., & Mano, H. (2008) · Genes to Cells · doi:10.1111/j.1365-2443.2008.01252.x · Cited by 161 · see citing works

A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo

Li, K., Blum, Y., Verma, A., Liu, Z., Pramanik, K., Leigh, N. R., Chun, C. Z., Samant, G. V., Zhao, B., Garnaas, M., et al. (2009) · Blood · doi:10.1182/blood-2009-09-242180 · Cited by 152 · see citing works

Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow

Lee, D.-Y., Lee, C.-I., Lin, T., Lim, S. H., Zhou, J., Tseng, Y.-C., Chien, S., & Chiu, J. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121214109 · Cited by 150 · see citing works

ATP-dependent chromatin remodeling shapes the DNA replication landscape

Vincent, J. A., Kwong, T. J., & Tsukiyama, T. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1419 · Cited by 149 · see citing works

The SWI/SNF Complex Creates Loop Domains in DNA and Polynucleosome Arrays and Can Disrupt DNA-Histone Contacts within These Domains

Bazett‐Jones, D. P., Côté, J., Landel, C. C., Peterson, C. L., & Workman, J. L. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.2.1470 · Cited by 146 · see citing works

Exploiting the Epigenome to Control Cancer-Promoting Gene-Expression Programs

Brien, G. L., Valerio, D. G., & Armstrong, S. A. (2016) · Cancer Cell · doi:10.1016/j.ccell.2016.03.007 · Cited by 146 · see citing works

Clinical trial on 5-AZA-2′-deoxycytidine in patients with acute leukemia

Momparler, R. L., Rivard, G. E., & Gyger, M. (1985) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(85)90052-x · Cited by 143 · see citing works

Tracing dynamic changes of DNA methylation at single cell resolution

Stelzer, Y., Shivalila, C. S., Soldner, F., Markoulaki, S., & Jaenisch, R. (2015) · Cell · doi:10.1016/j.cell.2015.08.046 · Cited by 141 · see citing works

Nucleosome structural studies

Tan, S., & Davey, C. A. (2010) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2010.11.006 · Cited by 139 · see citing works

Real-time imaging of histone H4 hyperacetylation in living cells

Sasaki, K., Ito, T., Nishino, N., Khochbin, S., & Yoshida, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902150106 · Cited by 137 · see citing works

Enhanced top-down characterization of histone post-translational modifications

Tian, Z., Tolić, N., Zhao, R., Moore, R. J., Hengel, S. M., Robinson, E. W., Stenoien, D. L., Wu, S., Smith, R. D., & Paša‐Tolić, L. (2012) · Genome biology · doi:10.1186/gb-2012-13-10-r86 · Cited by 127 · see citing works

Dynamics of Nucleosomes Assessed with Time-Lapse High-Speed Atomic Force Microscopy

Miyagi, A., Ando, T., & Lyubchenko, Y. L. (2011) · Biochemistry · doi:10.1021/bi200946z · Cited by 124 · see citing works

The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development

Griffin, C. T., Brennan, J. A., & Magnuson, T. (2007) · Development · doi:10.1242/dev.010090 · Cited by 121 · see citing works

Histone Acetylation Modifiers in the Pathogenesis of Alzheimer’s Disease

Lu, X., Wang, L., Yu, C., Yu, D., & Yu, G. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00226 · Cited by 116 · see citing works

Quantitative sequential chromatin immunoprecipitation, a method for analyzing co-occupancy of proteins at genomic regions in vivo

Geisberg, J. V. (2004) · Nucleic Acids Research · doi:10.1093/nar/gnh148 · Cited by 107 · see citing works

CpG methylation regulates the Igf2/H19 insulator

Holmgren, C., Kanduri, C., Dell, G. C., Ward, A., Mukhopadhya, R., Kanduri, M., Lobanenkov, V. V., & OHLSSON, R. I. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00314-1 · Cited by 92 · see citing works

Epigenetic Mechanism in Regulation of Endothelial Function by Disturbed Flow: Induction of DNA Hypermethylation by DNMT1

Zhou, J., Li, Y.-S. J., Wang, K.-C., & Chien, S. (2014) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-014-0325-z · Cited by 90 · see citing works

A High-Resolution Imaging Approach to Investigate Chromatin Architecture in Complex Tissues

Linhoff, M. W., Garg†, S. K., & Mandel, G. (2015) · Cell · doi:10.1016/j.cell.2015.09.002 · Cited by 82 · see citing works

Transcriptional Profiling Uncovers a Network of Cholesterol-Responsive Atherosclerosis Target Genes

Skogsberg, J., Lundström, J., Kovacs, A., Nilsson, R., Noori, P., Maleki, S., Köhler, M., Hamsten, A., Tegner, J. N., & Björkegren, J. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000036 · Cited by 79 · see citing works

Arterial endothelial methylome: differential DNA methylation in athero-susceptible disturbed flow regions in vivo

Jiang, Y.-Z., Manduchi, E., Stoeckert, C. J., & Davies, P. F. (2015) · BMC Genomics · doi:10.1186/s12864-015-1656-4 · Cited by 62 · see citing works

Histone deacetylases as therapeutic targets — From cancer to cardiac disease

Abend, A., & Kehat, I. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.11.003 · Cited by 58 · see citing works

Cracking the chromatin code: Precise rule of nucleosome positioning

Trifonov, E. N. (2011) · Physics of Life Reviews · doi:10.1016/j.plrev.2011.01.004 · Cited by 55 · see citing works

A preoccupied position on nucleosomes

Pugh, B. F. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb0810-923 · Cited by 45 · see citing works

ReCoGnizing methylated DNA.

Wade, P. A., & Wolffe, A. P. (2001) · Nature Structural Biology · doi:10.1038/89593 · Cited by 37 · see citing works

A Global Clustering Algorithm to Identify Long Intergenic Non-Coding RNA - with Applications in Mouse Macrophages

Garmire, L. X., Garmire, D. G., Huang, W. J. M., Yao, J., Glass, C. K., & Subramaniam, S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024051 · Cited by 27 · see citing works

Additive Effect of ANRIL and BRAP Polymorphisms on Ankle-Brachial Index in a Taiwanese Population

Tsai, P., Liao, Y., Lin, T., Hsi, E., Yang, Y., & Juo, S. H. (2011) · Circulation Journal · doi:10.1253/circj.cj-11-0925 · Cited by 27 · see citing works

Bayesian integration of genetics and epigenetics detects causal regulatory SNPs underlying expression variability

Das, A., Morley, M. P., Moravec, C. S., Tang, W. H. W., Hakonarson, H. H., Ashley, E. A., Brandimarto, J., Hu, R., Li, M., Li, H., et al. (2015) · Nature Communications · doi:10.1038/ncomms9555 · Cited by 25 · see citing works

Preparation of a Monoclonal Antibody Specific for 5-Methyl-2'-deoxycytidine and Its Application for the Detection of DNA Methylation Levels in Human Peripheral Blood Cells.

Mizugaki, M., Itoh, K., YAMAGUCHI, T., Ishiwata, S., Hishinuma, T., 野崎, 征., & Ishida, N. (1996) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.19.1537 · Cited by 15 · see citing works

Brain Lateralization: A Comparative Perspective.

Güntürkün, O., Ströckens, F., & Ocklenburg, S. (2020) · Physiological Reviews · doi:10.1152/physrev.00006.2019 · Cited by 412 · see citing works

Alveolar Epithelial Type II Cells as Drivers of Lung Fibrosis in Idiopathic Pulmonary Fibrosis

Parimon, T., Yao, C., Stripp, B. R., Noble, P. W., & Chen, P. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072269 · Cited by 386 · see citing works

Idiopathic Pulmonary Fibrosis: An Update on Pathogenesis

Mei, Q., Liu, Z., Zuo, H., Yang, Z., & Qu, J. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.797292 · Cited by 360 · see citing works

Vascular mechanotransduction

Davis, M. J., Earley, S., Li, Y.-S., & Chien, S. (2023) · Physiological Reviews · doi:10.1152/physrev.00053.2021 · Cited by 273 · see citing works

Phosphoenolpyruvate carboxykinase in cell metabolism: Roles and mechanisms beyond gluconeogenesis

Yu, S., Meng, S., Xiang, M., & Ma, H. (2021) · Molecular Metabolism · doi:10.1016/j.molmet.2021.101257 · Cited by 268 · see citing works

Molecular networks in Network Medicine: Development and applications

Silverman, E. K., Schmidt, H. H. H. W., Anastasiadou, E., Altucci, L., Angelini, M., Badimón, L., Balligand, J., Benincasa, G., Capasso, G., Conte, F., et al. (2020) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1489 · Cited by 211 · see citing works

Oxygen radical disease in the newborn, revisited: Oxidative stress and disease in the newborn period

Perez, M., Robbins, M. E., Revhaug, C., & Saugstad, O. D. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.03.035 · Cited by 198 · see citing works

Epigenetics of Alzheimer’s Disease

Perković, M. N., Paska, A. V., Konjevod, M., Kouter, K., Štrac, D. Š., Erjavec, G. N., & Pivac, N. (2021) · Biomolecules · doi:10.3390/biom11020195 · Cited by 181 · see citing works

Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function

Miao, Y., Ajami, N. E., Huang, T.-S., Lin, F., Lou, C., Wang, Y., Li, S., Kang, J., Munkacsi, H., Maurya, M. R., et al. (2018) · Nature Communications · doi:10.1038/s41467-017-02113-y · Cited by 176 · see citing works

Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis

Yang, G., Yuan, Y., Yuan, H., Wang, J., Yun, H., Geng, Y., Zhao, M., Li, L., Weng, Y., Liu, Z., et al. (2020) · EMBO Reports · doi:10.15252/embr.202050967 · Cited by 165 · see citing works

Genetic and epigenetic regulation of human aging and longevity

Morris, B. J., Willcox, B. J., & Donlon, T. A. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.08.039 · Cited by 140 · see citing works

Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity

Lauschke, V. M., Zhou, Y., & Ingelman‐Sundberg, M. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.01.002 · Cited by 134 · see citing works

CRISPR-Mediated Engineering across the Central Dogma in Plant Biology for Basic Research and Crop Improvement

Pramanik, D., Shelake, R. M., Kim, M. J., & Kim, J. (2020) · Molecular Plant · doi:10.1016/j.molp.2020.11.002 · Cited by 109 · see citing works

Direct cell reprogramming for tissue engineering and regenerative medicine

Grath, A., & Dai, G. (2019) · Journal of Biological Engineering · doi:10.1186/s13036-019-0144-9 · Cited by 109 · see citing works

Targeting epigenetic regulatory machinery to overcome cancer therapy resistance

Guo, L., Lee, Y., Zhou, Y., & Huang, Y. (2021) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2020.12.022 · Cited by 96 · see citing works

The Physics of Cellular Decision Making During Epithelial–Mesenchymal Transition

Tripathi, S., Levine, H., & Jolly, M. K. (2020) · Annual Review of Biophysics · doi:10.1146/annurev-biophys-121219-081557 · Cited by 88 · see citing works

Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury

Lai, J.-J., Cruz, F. M., & Rock, K. L. (2020) · Immunity · doi:10.1016/j.immuni.2019.11.013 · Cited by 84 · see citing works

KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1

Liu, L., Cui, J., Zhao, Y., Liu, X., Chen, L., Xia, Y., Wang, Y., Chen, S., Sun, S., Shi, B., et al. (2021) · Molecular Cancer · doi:10.1186/s12943-021-01369-9 · Cited by 87 · see citing works

Use of an Exposome Approach to Understand the Effects of Exposures From the Natural, Built, and Social Environments on Cardio-Vascular Disease Onset, Progression, and Outcomes

Juárez, P. D., Hood, D. B., Song, M., & Ramesh, A. (2020) · Frontiers in Public Health · doi:10.3389/fpubh.2020.00379 · Cited by 86 · see citing works

The Promises and Challenges of Toxico-Epigenomics: Environmental Chemicals and Their Impacts on the Epigenome

Chung, F. F., & Herceg, Z. (2020) · Environmental Health Perspectives · doi:10.1289/ehp6104 · Cited by 86 · see citing works

Recoding the Cancer Epigenome by Intervening in Metabolism and Iron Homeostasis with Mitochondria‐Targeted Rhenium(I) Complexes

Pan, Z., Tan, C., Rao, L., Zhang, H., Zheng, Y., Liang, H., Ji, L., & Mao, Z. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202008624 · Cited by 83 · see citing works

Pathological Role of HDAC8: Cancer and Beyond

Kim, J. Y., Cho, H., Yoo, J. H., Kim, G. W., Jeon, Y. H., Lee, S. W., & Kwon, S. H. (2022) · Cells · doi:10.3390/cells11193161 · Cited by 79 · see citing works

Epigenetic mechanisms of drug resistance in fungi

Chang, Z., Yadav, V., Lee, S. C., & Heitman, J. (2019) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2019.103253 · Cited by 81 · see citing works

Nanomedicine and epigenome. Possible health risks

Smolková, B., Dušinská, M., & Gábelová, A. (2017) · Food and Chemical Toxicology · doi:10.1016/j.fct.2017.07.020 · Cited by 70 · see citing works

Diabetic nephropathy: The regulatory interplay between epigenetics and microRNAs

Sankrityayan, H., Kulkarni, Y. A., & Gaikwad, A. B. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.01.043 · Cited by 62 · see citing works

Histone deacetylases and their inhibitors in inflammatory diseases

Zhang, S.-Y., Zhang, L., Wen, R., Yang, N., & Zhang, T. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117295 · Cited by 62 · see citing works

LncRNA regulation: New frontiers in epigenetic solutions to drug chemoresistance

Zhou, Y., Sun, W. C., Qin, Z., Guo, S., Kang, Y., Zeng, S., & Yu, L. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114228 · Cited by 58 · see citing works

Epigenetic regulation of gene expression in response to environmental exposures: From bench to model

Li, D., Yang, Y. X., Li, Y., Zhu, X., & Li, Z. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.145998 · Cited by 56 · see citing works

Differential chromatin accessibility landscape reveals structural and functional features of the allopolyploid wheat chromosomes

Jordan, K. W., He, F., Soto, M. F. D., Akhunova, A. R., & Akhunov, E. (2020) · Genome biology · doi:10.1186/s13059-020-02093-1 · Cited by 55 · see citing works

Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model

Zeng, H., Li, T., He, X., Cai, S., Luo, H., Chen, P., & Chen, Y. (2020) · Respiratory Research · doi:10.1186/s12931-020-01495-w · Cited by 54 · see citing works

Atheroprone flow enhances the endothelial-to-mesenchymal transition

Lai, B., Li, Z., He, M., Wang, Y., Chen, L., Zhang, J., Yang, Y., & Shyy, J. Y.-J. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00213.2018 · Cited by 53 · see citing works

Epigenetic perpetuation of the impact of early life stress on behavior

Janusek, L. W., Tell, D., & Mathews, H. L. (2019) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2019.01.004 · Cited by 53 · see citing works

Non-genomic transmission of longevity between generations: potential mechanisms and evidence across species

Vaiserman, A. M., Koliada, A. K., & Jirtle, R. L. (2017) · Epigenetics & Chromatin · doi:10.1186/s13072-017-0145-1 · Cited by 53 · see citing works

Unknown to Known: Advancing Knowledge of Coral Gene Function

Cleves, P. A., Shumaker, A., Lee, J., Putnam, H. M., & Bhattacharya, D. (2019) · Trends in Genetics · doi:10.1016/j.tig.2019.11.001 · Cited by 53 · see citing works

Single-molecule optical genome mapping in nanochannels: multidisciplinarity at the nanoscale

Jeffet, J., Margalit, S., Michaeli, Y., & Ebenstein, Y. (2021) · Essays in Biochemistry · doi:10.1042/ebc20200021 · Cited by 52 · see citing works

Synthetic Genomics: From DNA Synthesis to Genome Design

Wang, L., Jiang, S., Chen, C., He, W., Wu, X., Wang, F., Tong, T., Zou, X., Li, Z., Luo, J., et al. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201708741 · Cited by 51 · see citing works

The Role of Hydrogen Sulfide (H2S) in Epigenetic Regulation of Neurodegenerative Diseases: A Systematic Review

Dogaru, B. G., & Munteanu, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241612555 · Cited by 51 · see citing works

YTHDF2 mediates LPS-induced osteoclastogenesis and inflammatory response via the NF-κB and MAPK signaling pathways

Fang, C., He, M., Li, D., & Xu, Q. (2021) · Cellular Signalling · doi:10.1016/j.cellsig.2021.110060 · Cited by 50 · see citing works

The Rich World of p53 DNA Binding Targets: The Role of DNA Structure

Brázda, V., & Fojta, M. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225605 · Cited by 48 · see citing works

Inhibitory activities of grape bioactive compounds against enzymes linked with human diseases

Dwibedi, V., Jain, S., Singhal, D., Mittal, A., Rath, S. K., & Saxena, S. (2022) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-022-11801-9 · Cited by 48 · see citing works

Clinical translation of nanomedicine with integrated digital medicine and machine learning interventions

Ahmad, F., & Muhmood, T. (2024) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2024.114041 · Cited by 46 · see citing works

A status-quo review on CRISPR-Cas9 gene editing applications in tomato

Chandrasekaran, M., Boopathi, T., & Manivannan, P. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.08.169 · Cited by 43 · see citing works

Hyperglycemia affects global 5-methylcytosine and 5-hydroxymethylcytosine in blood genomic DNA through upregulation of SIRT6 and TETs

Yuan, E., Yang, Y., Cheng, L. Z., Deng, X., Chen, S., Zhou, X. H., & Liu, S. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0660-y · Cited by 41 · see citing works

CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence

Crochemore, C., Molina, C. F., Montagne, B., Salles, A., & Ricchetti, M. (2019) · Nature Communications · doi:10.1038/s41467-019-13314-y · Cited by 40 · see citing works

Incretin drugs effect on epigenetic machinery: New potential therapeutic implications in preventing vascular diabetic complications

Scisciola, L., Rizzo, M. R., Cataldo, V., Fontanella, R. A., Balestrieri, M. L., D’Onofrio, N., Marfella, R., Paolisso, G., & Barbieri, M. (2020) · The FASEB Journal · doi:10.1096/fj.202000860rr · Cited by 41 · see citing works

A review of disrupted biological response associated with volatile organic compound exposure: Insight into identification of biomarkers

Shen, Q., Liu, Y., Li, G., & An, T. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.174924 · Cited by 40 · see citing works

The role of cullin4B in human cancers

Li, Y., & Wang, X. (2017) · Experimental Hematology and Oncology · doi:10.1186/s40164-017-0077-2 · Cited by 40 · see citing works

A novel bivalent chromatin associates with rapid induction of camalexin biosynthesis genes in response to a pathogen signal in Arabidopsis

Zhao, K., Kong, D., Jin, B., Smolke, C. D., & Rhee, S. Y. (2021) · eLife · doi:10.7554/elife.69508 · Cited by 39 · see citing works

Epigenetic basis of Alzheimer disease

Tecalco-Cruz, Á. C., Ramírez‐Jarquín, J. O., Álvarez-Sánchez, M. E., & Zepeda–Cervantes, J. (2020) · World Journal of Biological Chemistry · doi:10.4331/wjbc.v11.i2.62 · Cited by 37 · see citing works

Population Epigenomics: Advancing Understanding of Phenotypic Plasticity, Acclimation, Adaptation and Diseases

Moler, E. R. V., Abakir, A., Eleftheriou, M., Johnson, J. S., Krutovsky, K. V., Lewis, L. C., Ruzov, A. S., Whipple, A. V., & Rajora, O. P. (2018) · Population genomics · doi:10.1007/13836_2018_59 · Cited by 35 · see citing works

A four-methylated mRNA signature-based risk score system predicts survival in patients with hepatocellular carcinoma

Wang, Y., Ruan, Z., Yu, S., Tian, T., Liang, X., Li, J., Li, W., Wang, X., Xiang, L., Claret, F. X., et al. (2019) · Aging · doi:10.18632/aging.101738 · Cited by 35 · see citing works

AKT1/FOXP3 axis-mediated expression of CerS6 promotes p53 mutant pancreatic tumorigenesis

Qi, D., Song, X., Xue, C., Yao, W., Shen, P., Yu, H. T., & Zhang, Z. (2021) · Cancer Letters · doi:10.1016/j.canlet.2021.06.024 · Cited by 35 · see citing works

Formation of furan in baby food products: Identification and technical challenges

Javed, F., Shahbaz, H. M., Nawaz, A., Olaimat, A. N., Stratakos, A. C., Wahyono, A., Munir, S., Mueen‐ud‐Din, G., Ali, Z., & Park, J. (2021) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12732 · Cited by 34 · see citing works

Suspended in time: Molecular responses to hibernation also promote longevity

Al-attar, R., & Storey, K. B. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2020.110889 · Cited by 33 · see citing works

Prenatal Malnutrition-Induced Epigenetic Dysregulation as a Risk Factor for Type 2 Diabetes

Vaiserman, A. M., & Lushchak, O. V. (2019) · International Journal of Genomics · doi:10.1155/2019/3821409 · Cited by 34 · see citing works

Antifibrotic effects of sodium-glucose cotransporter-2 inhibitors: A comprehensive review

Shakour, N., Karami, S., Iranshahi, M., Butler, A. E., & Sahebkar, A. (2023) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2023.102934 · Cited by 31 · see citing works

Genomic patterns of transcription–replication interactions in mouse primary B cells

Germain, C. S., Zhao, H., Sinha, V., Sanz, L. A., Chedin, F. L., & Barlow, J. H. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac035 · Cited by 29 · see citing works

Selective Targeting of Epigenetic Readers and Histone Deacetylases in Autoimmune and Inflammatory Diseases: Recent Advances and Future Perspectives

Ghiboub, M., Elfiky, A. M. I., de Winther, M. P. J., Harker, N. R., Tough, D. F., & de Jonge, W. J. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11050336 · Cited by 28 · see citing works

Metabolic memory and diabetic nephropathy: Beneficial effects of natural epigenetic modifiers

Kushwaha, K., Sharma, S., & Gupta, J. (2020) · Biochimie · doi:10.1016/j.biochi.2020.01.007 · Cited by 28 · see citing works

Roles of LncRNAs in Regulating Mitochondrial Dysfunction in Septic Cardiomyopathy

Liu, S., & Chong, W. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.802085 · Cited by 28 · see citing works

The active role of spermatozoa in transgenerational inheritance

Sciamanna, I., Serafino, A., Shapiro, J. A., & Spadafora, C. (2019) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2019.1263 · Cited by 27 · see citing works

The role of epigenomic alterations in furan-induced hepatobiliary pathologies

de Conti, A., Beland, F. A., & Pogribny, I. P. (2017) · Food and Chemical Toxicology · doi:10.1016/j.fct.2017.07.049 · Cited by 26 · see citing works

Methylation of Estrogen Receptor 1 Gene in the Paraspinal Muscles of Girls with Idiopathic Scoliosis and Its Association with Disease Severity

Janusz, P., Chmielewska, M., Andrusiewicz, M., Kotwicka, M., & Kotwicki, T. (2021) · Genes · doi:10.3390/genes12060790 · Cited by 25 · see citing works

Regulatory loop between lncRNA FAS-AS1 and DNMT3b controls FAS expression in hydroquinone-treated TK6 cells and benzene-exposed workers

Yuan, Q., Zhang, H., Pan, Z., Ling, X., Wu, M., Gui, Z., Chen, J., Peng, J., Liu, Z., Tan, Q., et al. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.114147 · Cited by 24 · see citing works

Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease

Ortega, M. A., León-Oliva, D. D., Montero, C. G., Fraile‐Μartinez, O., Boaru, D. L., Toledo-Lobo, M. V., García‐Tuñón, I., Royuela, M., García‐Honduvilla, N., Buján, J., et al. (2023) · Genes · doi:10.3390/genes14040915 · Cited by 24 · see citing works

Trimethylacetic Anhydride–Based Derivatization Facilitates Quantification of Histone Marks at the MS1 Level

Kuchaříková, H., Dobrovolná, P., Lochmanová, G., & Zdráhal, Z. (2021) · Molecular & Cellular Proteomics · doi:10.1016/j.mcpro.2021.100114 · Cited by 21 · see citing works

Pt(IV)-Deferasirox Prodrug Combats DNA Damage Repair by Regulating RNA N 6 -Methyladenosine Methylation

Pan, Z., Ling, Y., Zhang, H., Liang, H., Tan, C., & Mao, Z. (2022) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.2c01224 · Cited by 21 · see citing works

Distinct Expression Pattern of Epigenetic Machinery Genes in Blood Leucocytes and Brain Cortex of Depressive Patients

Rey, R., Chauvet‐Gélinier, J., Suaud‐Chagny, M., Ragot, S., Bonin, B., d’Amato, T., & Teyssier, J. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1406-0 · Cited by 20 · see citing works

The Impact of Parasites on Host Insect Epigenetics

Vilcinskas, A. (2017) · Advances in insect physiology · doi:10.1016/bs.aiip.2017.05.001 · Cited by 20 · see citing works

Methylation of estrogen receptor 2 (ESR2) in deep paravertebral muscles and its association with idiopathic scoliosis

Chmielewska, M., Janusz, P., Andrusiewicz, M., Kotwicki, T., & Kotwicka, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-78454-4 · Cited by 20 · see citing works

Fatty acid-binding protein 5 limits ILC2-mediated allergic lung inflammation in a murine asthma model

Kobayashi, S., Tayama, S., Phung, H. T., Kagawa, Y., Miyazaki, H., Takahashi, Y., Maruyama, T., Ishii, N., & Owada, Y. (2020) · Scientific Reports · doi:10.1038/s41598-020-73935-y · Cited by 18 · see citing works

Environmental Exposures and Epigenetic Perturbations

Pogribny, I. P. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65062-6 · Cited by 17 · see citing works

Somatic Lineage ReprogrammingPreprint

Shelby, H., Shelby, T., & Wernig, M. (2021) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a040808 · Cited by 15 · see citing works

Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines

Köse-Vogel, N., Stengel, S., Gardey, E., Kirchberger-Tolstik, T., Reuken, P. A., Stallmach, A., & Bruns, T. (2019) · Cells · doi:10.3390/cells9010079 · Cited by 16 · see citing works

New insight in molecular mechanisms regulating SIRT6 expression in diabetes: Hyperglycaemia effects on SIRT6 DNA methylation

Scisciola, L., Rizzo, M. R., Marfella, R., Cataldo, V., Fontanella, R. A., Boccalone, E., Paolisso, G., & Barbieri, M. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.30185 · Cited by 16 · see citing works

Revisiting Epigenetics Fundamentals and Its Biomedical Implications

Meza-Menchaca, T., Albores-Medina, A., Heredia-Mendez, A. J., Ruíz-May, E., Ricaño-Rodríguez, J., Gallegos-García, V., Esquivel, A., Vettoretti-Maldonado, G., & Campos-Parra, A. D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147927 · Cited by 15 · see citing works

4-Nonylphenol-Enhanced EZH2 and RNF2 Expression, H3K27me3 and H2AK119ub1 Marks Resulting in Silencing of p21 CDKN1A in Vitro

Ghosh, K. K., Chatterjee, B., Maheswari, U., Athifa, M., & Kanade, S. R. (2019) · Epigenomics · doi:10.2217/epi-2018-0175 · Cited by 15 · see citing works

Molecular mechanisms of T helper 17 cell differentiation: Emerging roles for transcription cofactors

Jiang, Y., Wang, X., & Dong, C. (2019) · Advances in immunology · doi:10.1016/bs.ai.2019.09.003 · Cited by 15 · see citing works

The KDM6A-SPARCL1 axis blocks metastasis and regulates the tumour microenvironment of gastrointestinal stromal tumours by inhibiting the nuclear translocation of p65

Shen, C., Han, L., Liu, B., Zhang, G., Cai, Z., Yin, X., Yin, Y., Chen, Z., & Zhang, B. (2022) · British Journal of Cancer · doi:10.1038/s41416-022-01728-3 · Cited by 15 · see citing works

Current Evidence on the Role of Epigenetic Mechanisms in Migraine: The Way Forward to Precision Medicine

Gazerani, P. (2018) · OBM Genetics · doi:10.21926/obm.genet.1804040 · Cited by 15 · see citing works

Psychogenetic, genetic and epigenetic mechanisms in Candida auris: Role in drug resistance

Rabaan, A. A., Eljaaly, K., Alfouzan, W. A., Mutair, A. A., Alhumaid, S., Alfaraj, A. H., Aldawood, Y., Alsaleh, A. A., Albayat, H., Azmi, R. A., et al. (2023) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2022.12.012 · Cited by 14 · see citing works

IL-27 induces autophagy through regulation of the DNMT1/lncRNA MEG3/ERK/p38 axis to reduce pulmonary fibrosis

Ting, L., Feng, Y., Zhou, Y., Tong, Z., & Dong, Z. (2023) · Respiratory Research · doi:10.1186/s12931-023-02373-x · Cited by 14 · see citing works

Epigenetic modulation of fungal pathogens: a focus on Magnaporthe oryzae

Aslam, H. M. U., Chikh-Ali, M., Zhou, X., Zhang, S., Harris, S., Chanda, A. K., Riaz, H., Hameed, A., Aslam, S., & Killiny, N. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1463987 · Cited by 14 · see citing works

Molecular Mechanism of Mesenchyme Homeobox 1 in Transforming Growth Factor β1–Induced P311 Gene Transcription in Fibrosis

Wei, Z., Han, C., Li, H., He, W., Zhou, J., Dong, H. F., Wu, Y., Tian, Y., & Luo, G. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.00059 · Cited by 14 · see citing works

A Conformational Switch in the Zinc Finger Protein Kaiso Mediates Differential Readout of Specific and Methylated DNA Sequences

Nikolova, E. N., Stanfield, R. L., Dyson, H. J., & Wright, P. E. (2020) · Biochemistry · doi:10.1021/acs.biochem.0c00253 · Cited by 14 · see citing works

Lupus nephritis: The regulatory interplay between epigenetic and MicroRNAs

Xu, N., Liu, J., & Li, X. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.925416 · Cited by 13 · see citing works

Fatty acid‐binding protein 3 regulates differentiation of IgM‐producing plasma cells

Kobayashi, S., Phung, H. T., Tayama, S., Kagawa, Y., Miyazaki, H., Yamamoto, Y., Maruyama, T., Ishii, N., & Owada, Y. (2020) · FEBS Journal · doi:10.1111/febs.15460 · Cited by 13 · see citing works

Changes in DNA methylation and histone modification gene expression in response to daily food times in zebra finches: epigenetic implications

Mishra, I., Sharma, A., Prabhat, A., Batra, T., Malik, I., & Kumar, V. (2020) · Journal of Experimental Biology · doi:10.1242/jeb.217422 · Cited by 12 · see citing works

Loci specific epigenetic drug sensitivity

Zhang, T., Pilko, A., & Wollman, R. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa210 · Cited by 12 · see citing works

Euchromatin histone methyltransferase II (EHMT2) regulates the expression of ras-related GTP binding C (RRAGC) protein

Hwang, S., Kim, S.-Y., Kim, K., Yeom, J., Park, S., & Kim, I. (2020) · BMB Reports · doi:10.5483/bmbrep.2020.53.11.055 · Cited by 12 · see citing works

Circular RNAs and their roles in idiopathic pulmonary fibrosis

Surendran, A. M., Huang, C., & Liu, L. (2024) · Respiratory Research · doi:10.1186/s12931-024-02716-2 · Cited by 12 · see citing works

Small molecule epigenetic modulators for enhancing recombinant antibody production in CHO cell cultures

Kim, D., Yoon, C., & Lee, G. M. (2021) · Biotechnology and Bioengineering · doi:10.1002/bit.28013 · Cited by 11 · see citing works

MicroRNA and Nonsense Transcripts as Putative Viral Evasion Mechanisms

Bakre, A. A., Maleki, A., & Tripp, R. A. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00152 · Cited by 11 · see citing works

A Novel Application of Mixed Effects Models for Reconciling Base-Pair Resolution 5-Methylcytosine and 5-Hydroxymethylcytosine Data in Neuroepigenetics

Kochmanski, J. J., Savonen, C., & Bernstein, A. I. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00801 · Cited by 11 · see citing works

The emerging role of SARS-CoV-2 nonstructural protein 1 (nsp1) in epigenetic regulation of host gene expression

Ivanov, K. I., Yang, H., Sun, R., Li, C., & Guo, D. (2024) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuae023 · Cited by 10 · see citing works

Ecology of timekeeping: feeding times effect clock-controlled behavior, metabolism and reproduction in diurnal vertebrates

Tripathi, V., Bhardwaj, S. K., & Kumar, V. (2025) · npj Biological Timing and Sleep · doi:10.1038/s44323-025-00022-8 · Cited by 10 · see citing works

Experimental and Computational Approaches to Direct Cell Reprogramming: Recent Advancement and Future Challenges

Gam, R., Sung, M. K., & Pandurangan, A. P. (2019) · Cells · doi:10.3390/cells8101189 · Cited by 10 · see citing works

A novel dual-epigenetic inhibitor enhances recombinant monoclonal antibody expression in CHO cells

Han, M., Wang, H.-T., Zhang, H., Lu, J., Guo, J., Qiu, L.-L., Zhang, X., Wang, X., Wang, T., & Jia, Y. (2024) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-024-13302-3 · Cited by 9 · see citing works

Renal function in very old critically ill patients

Perschinka, F., Boyer, N., Forni, L. G., & Joannidis, M. (2023) · Current Opinion in Critical Care · doi:10.1097/mcc.0000000000001088 · Cited by 8 · see citing works

Epigenetic Regulation of Angiogenesis in Peripheral Artery Disease

Malhi, N. K., Southerland, K. W., Lai, L., & Chen, Z. (2023) · Methodist DeBakey Cardiovascular Journal · doi:10.14797/mdcvj.1294 · Cited by 8 · see citing works

Epitranscriptional Regulation: From the Perspectives of Cardiovascular Bioengineering

Chen, Z., He, M., Li, J. Y.-S., Shyy, J. Y.-J., & Chien, S. (2023) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-081922-021233 · Cited by 3 · see citing works

Epigenomic Reprogramming in Cardiovascular Disease

Zhou, Y., Liu, J., & Li, Q. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814513-5.00010-6 · Cited by 5 · see citing works

Epigenomes in Cardiovascular Disease

Rosa‐Garrido, M., Chapski, D. J., & Vondriska, T. M. (2018) · Circulation Research · doi:10.1161/circresaha.118.311597 · Cited by 71 · see citing works

Role of epigenetics in cardiovascular diseases: An out and out check

Wasim, R., Mahmood, T., Siddiqui, M. H., Singh, A. N., Ahmad, A., & Ahsan, F. (2023) · Intelligent Pharmacy · doi:10.1016/j.ipha.2023.09.001 · Cited by 2 · see citing works

Epigenetic Regulations in Mammalian Cells: Roles and Profiling Techniques

Kim, U., & Lee, D.-S. (2023) · Molecules and Cells · doi:10.14348/molcells.2023.0013 · Cited by 26 · see citing works