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Tauroursodeoxycholic Acid Protects Retinal and Visual Function in a Mouse Model of Type 1 Diabetes

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A comprehensive review on wedelolactone: natural sources, total synthesis, and pharmacological activities

Cai, H., Wu, Y., & Zhang, X. (2025) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(25)60821-1 · Cited by 12 · see citing works

Pharmacological Screening of Viola odorata L. for Memory-Enhancing Effect via Modulation of Oxidative Stress and Inflammatory Biomarkers

Saleem, U., Hira, S., Anwar, F., Shah, M. A., Bashir, S., Baty, R. S., Badr, R. H., Blundell, R. A., Batiha, G. E., & Ahmad, B. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.664832 · Cited by 12 · see citing works

Curcumin attenuates memory impairments and long-term potentiation deficits by damping hippocampal inflammatory cytokines in lipopolysaccharide-challenged rats

Hajipour, S., Vastegani, S. M., Sarkaki, A., Basir, Z., Navabi, S. P., Farbood, Y., & Khoshnam, S. E. (2023) · Metabolic Brain Disease · doi:10.1007/s11011-023-01169-8 · Cited by 12 · see citing works

TGR5 signalling in heart and brain injuries: focus on metabolic and ischaemic mechanisms

Xu, N., He, Y., Zhang, C., Zhang, Y., Cheng, S., Deng, L. Q., 田中, 義., Liao, B., Wei, Y., & Feng, J. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106428 · Cited by 10 · see citing works

The Biological Changes of Synaptic Plasticity in the Pathological Process of Sepsis-associated Encephalopathy

Yang, L., Li, J., Liu, F., Chai, X., Fang, Z., & Zhang, X. (2024) · Current Neuropharmacology · doi:10.2174/1570159x23666241028105746 · Cited by 10 · see citing works

Decoding TGR5: A comprehensive review of its impact on cerebral diseases

Zhang, Z., Zhang, Y., Peng, H., Yu, Q., Kang, X., Liu, Y., Zheng, Y., Cheng, F., Wang, X., & Li, F. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107671 · Cited by 10 · see citing works

The Metabolomic Mind: Microbial Metabolite Programming of Microglia

Verosky, B. G., Bailey, M. T., & Gur, T. (2025) · NeuroImmunoModulation · doi:10.1159/000545484 · Cited by 9 · see citing works

AMX0035 Mitigates Oligodendrocyte Apoptosis and Ameliorates Demyelination in MCAO Rats by Inhibiting Endoplasmic Reticulum Stress and Mitochondrial Dysfunction

Zhang, L., Bian, C., Wang, Y., Wei, L., Sun, S., & Liu, Q. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26083865 · Cited by 9 · see citing works

The microbiota-gut-brain axis in Huntington’s disease: Evidence, mechanisms and therapeutic opportunities

Gu, Y., Wang, M., & Mao, Y. (2026) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2026.101247 · Cited by 8 · see citing works

Tauroursodeoxycholic Acid Inhibits NF-κB/p300/H3K14ac to Attenuate Microglial Activation in Lipopolysaccharide-treated BV-2 Cells and Mice

Qi, D., Yi, R., Yang, J., Qiu, X., Huang, J., Liu, Z., Liu, Y., Qi, J., & Li, Y. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05619-5 · Cited by 4 · see citing works

Microbiota–gut–brain axis and bile acids–driven neuromodulation

Dong, T., Zhang, T., Wang, H., Zhang, J., Abdullah, R., Sun, B., & Peng, G. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-25-00927 · Cited by 4 · see citing works

Aqueous Extract of Lycium ruthenicum Murray Attenuates Neuroinflammation in C57BL/6J Mice Induced by High-Fat and High-Fructose Diet Through Regulating Gut Microbiota and Bile Acid Metabolism

Fan, X., Dong, W., Huang, Y., Shu, Y., Yan, Y., Mi, J., Lu, L., Zeng, X., & Cao, Y. (2024) · Foods · doi:10.3390/foods13233812 · Cited by 4 · see citing works

Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury

Hou, Y., Zhang, Y., Ma, L., Luo, D., Wang, W., Shunmei, E., Huang, C., Hou, Y., Chen, S., Zhan, J., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1554945 · Cited by 5 · see citing works

Cholinergic G protein‐coupled bile acid receptor 1 (TGR5/GPBA) in the medial septal orchestrates adult hippocampal neurogenesis and cognition in Alzheimer's disease mice

Nie, R., Zhang, Q., Tan, X., Hu, S., Zhou, X., Jiang, W., Guo, B., Cao, X., Yuan, D., Long, Y., et al. (2025) · British Journal of Pharmacology · doi:10.1111/bph.70185 · Cited by 3 · see citing works

Endothelial IRE1 signaling maintains blood–brain barrier integrity and limits neuroinflammation after traumatic brain injury

Fan, Q., Takarada‐Iemata, M., Tanaka, T., Nguyen, L. D., Okitani, N., Yang, R., Tamatani, T., Ishii, H., Hattori, T., Kidoya, H., et al. (2026) · Cell Death and Disease · doi:10.1038/s41419-026-08461-2 · Cited by 2 · see citing works

Corticosterone‐Induced Myocardial Dysfunctions and the Cardioprotective Role of Tauroursodeoxycholic Acid: An Experimental Study in Mice

Zhou, H., Chen, X., Tao, Y., Li, Z., Wu, H., Shi, H., Wu, X., & Huang, F. (2025) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.70027 · Cited by 2 · see citing works

Synergistic Neuroprotective Effects of Taurine and Tauroursodeoxycholic Acid on the Neurovascular Unit in Hypoxia-Reoxygenation Injury

Du, X., Li, S., Wu, G., Cai, H., Sun, C.-Y., Lin, H., Cai, Y.-F., & Wang, Q. (2026) · Rejuvenation Research · doi:10.1177/15491684251409076 · Cited by 1 · see citing works

Multi-omics analysis highlights the link of aging-related cognitive decline with systemic inflammation and alterations of tissue-maintenancePreprint

Flor, S., Dost, T., Haase, M., Simon, R., Ederer, S., Kadibalban, A. S., Taubenheim, J., Olecka, M., Walker, A., Zimmermann, J., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.13.662751 · Cited by 2 · see citing works

Tauroursodeoxycholic Acid Alleviates Secondary Injury in Spinal Cord Injury Mice Through Reducing Oxidative Stress, Apoptosis, and Inflammatory ResponsePreprint

Hou, Y., Luan, J., Deng, T., Huang, T., Li, X., Xiao, Z., Zhan, J., Luo, D., Hou, Y., Xu, L., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-361252/v1

The Combined Use of SCD Probiotics and Tauroursodeoksikolik Asit (TUDCA) is More Effective in Controlling Anxiety-Like Behavior in Aged Rats

Ceylani, T., & Teker, H. T. (2023) · Bitlis Eren Üniversitesi Fen Bilimleri Dergisi · doi:10.17798/bitlisfen.1231238

TGR5 protects against pSNL-induced mechanical allodynia by alleviating neuroinflammation in the injured nerves of male micePreprint

Shi, W.-G., Yao, Y., Liang, Y., Lei, J., Feng, S., Tian, Y., Zhang, Z.-X., Cai, J., Xing, G., & Fu, K. (2024) · Research Square · doi:10.21203/rs.3.rs-3852075/v1

Bear Bile Powder Alleviates Corticosterone-induced Depression-like Behavior in Female Mice by Protecting Hippocampal Neurons via the BDNF/TrkB/ CREB Pathway

Shen, W., Li, Z., Tao, Y., Zhou, H., Wu, H., Shi, H., Huang, F., & Wu, X. (2025) · Current Pharmaceutical Design · doi:10.2174/0113816128369486250519021344

Beyond the optic disc: Investigating gender-based differences in optic neuritis

Zeppieri, M., Nicolosi, S. G., D’Esposito, F., Musa, M., Avitabile, A., Gagliano, C., Battista, M., Barboni, P., & Capobianco, M. (2025) · World Journal of Clinical Cases · doi:10.12998/wjcc.v13.i32.111134

Additional file 1 of Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response

Hou, Y., Luan, J., Huang, T., Deng, T., Li, X., Xiao, Z., Zhan, J., Luo, D., Hou, Y., Xu, L., et al. (2021) · Figshare · doi:10.6084/m9.figshare.16650125

Combination Pharmacology for ALS: A Mechanistic Rationale

Rosenfeld, J., Salomon‐Zimri, S., & Tracik, F. M. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27167404

Tauroursodeoxycholic acid reduces glial cell activation in an animal model of acute neuroinflammation

Yanguas-Casás, N., Barreda-Manso, M. A., Nieto-Sampedro, M., & Romero-Ramírez, L. (2014) · Journal of Neuroinflammation · doi:10.1186/1742-2094-11-50 · Cited by 103 · see citing works

TGFβ Contributes to the Anti-inflammatory Effects of Tauroursodeoxycholic Acid on an Animal Model of Acute Neuroinflammation

Yanguas‐Casás, N., Barreda-Manso, M. A., Pérez-Rial, S., Nieto‐Sampedro, M., & Romero‐Ramírez, L. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0142-6 · Cited by 36 · see citing works

Tauroursodeoxycholic Acid Inhibits NF-κB/p300/H3K14ac to Attenuate Microglial Activation in Lipopolysaccharide-treated BV-2 Cells and Mice

Qi, D., Yi, R., Yang, J., Qiu, X., Huang, J., Liu, Z., Liu, Y., Qi, J., & Li, Y. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05619-5 · Cited by 4 · see citing works

Ursolic acid attenuates LPS-induced cognitive dysfunction through the modulation of oxidative stress, neuroinflammation, and hippocampal synaptic plasticity

Choi, G.-Y., Lee, S., Je, A. R., Choi, H., Moon, E., Cho, E., Kwon, S., Lee, K., & Kweon, H. (2026) · Phytomedicine · doi:10.1016/j.phymed.2026.158788

Pharmacological Activation of GPR55 Improved Cognitive Impairment Induced by Lipopolysaccharide in Mice

Wang, X., Xiang, X., Hu, J., Wu, Y., Li, Y., Jin, S., & Wu, X. G. (2022) · Journal of Molecular Neuroscience · doi:10.1007/s12031-022-02020-y · Cited by 18 · see citing works