The mannose receptor: linking homeostasis and immunity through sugar recognition

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

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Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation

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The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

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The Dendritic Cell-Specific Adhesion Receptor DC-SIGN Internalizes Antigen for Presentation to T Cells

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The mannose receptor family

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The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments

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Diversity of receptors binding HIV on dendritic cell subsets

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Molecular characterization of the human macrophage mannose receptor: demonstration of multiple carbohydrate recognition-like domains and phagocytosis of yeasts in Cos-1 cells.

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Mannose Receptor-Mediated Regulation of Serum Glycoprotein Homeostasis

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Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor

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Mannosylated Lipoarabinomannans Inhibit IL-12 Production by Human Dendritic Cells: Evidence for a Negative Signal Delivered Through the Mannose Receptor

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The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells

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Primary structure of the mannose receptor contains multiple motifs resembling carbohydrate-recognition domains.

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Cross-Linking of the Mannose Receptor on Monocyte-Derived Dendritic Cells Activates an Anti-Inflammatory Immunosuppressive Program

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Identification of committed NK cell progenitors in adult murine bone marrow

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The Mannose Receptor Delivers Lipoglycan Antigens to Endosomes for Presentation to T Cells by CD1b Molecules

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Contribution to ligand binding by multiple carbohydrate-recognition domains in the macrophage mannose receptor.

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Mannose receptor‐mediated uptake of antigens strongly enhances HLA class II‐restricted antigen presentation by cultured dendritic cells

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Interleukin‐13 alters the activation state of murine macrophages in vitro: Comparison with interleukin‐4 and interferon‐γ

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Mannose Receptor and Its Putative Ligands in Normal Murine Lymphoid and Nonlymphoid Organs: In Situ Expression of Mannose Receptor by Selected Macrophages, Endothelial Cells, Perivascular Microglia, and Mesangial Cells, but not Dendritic Cells

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Involvement of macrophage mannose receptor in the binding and transmission of HIV by macrophages

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The Human 180-kDa Receptor for Secretory Phospholipases A2

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Recognition of Bacterial Capsular Polysaccharides and Lipopolysaccharides by the Macrophage Mannose Receptor

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Mechanisms of host defense against Candida species. I. Phagocytosis by monocytes and monocyte-derived macrophages

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Normal Host Defense during Systemic Candidiasis in Mannose Receptor-Deficient Mice

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A cysteine-rich domain of the “mannose” receptor mediates GalNAc-4-SO 4 binding

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The Chicken Yolk Sac IgY Receptor, a Functional Equivalent of the Mammalian MHC-Related Fc Receptor, Is a Phospholipase A2 Receptor Homolog

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Involvement of mannose receptor in cytokine interleukin-1beta (IL-1beta), IL-6, and granulocyte-macrophage colony-stimulating factor responses, but not in chemokine macrophage inflammatory protein 1beta (MIP-1beta), MIP-2, and KC responses, caused by attachment of Candida albicans to macrophages

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Endo180, an endocytic recycling glycoprotein related to the macrophage mannose receptor is expressed on fibroblasts, endothelial cells and macrophages and functions as a lectin receptor

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The Cysteine-Rich Domain of the Macrophage Mannose Receptor Is a Multispecific Lectin That Recognizes Chondroitin Sulfates a and B and Sulfated Oligosaccharides of Blood Group Lewisa and Lewisx Types in Addition to the Sulfated N-Glycans of Lutropin

Leteux, C., Chai, W., Loveless, R. W., Yuen, C., Uhlin‐Hansen, L., Combarnous, Y., Janković, M., Maric, S. C., Misulovin, Z., Nussenzweig, M. C., et al. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.191.7.1117 · Cited by 168 · see citing works

Mannose Receptor Is a Novel Ligand for L-Selectin and Mediates Lymphocyte Binding to Lymphatic Endothelium

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Characterization of the murine macrophage mannose receptor: demonstration that the downregulation of receptor expression mediated by interferon-gamma occurs at the level of transcription

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Fc chimeric protein containing the cysteine-rich domain of the murine mannose receptor binds to macrophages from splenic marginal zone and lymph node subcapsular sinus and to germinal centers.

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Pulmonary Surfactant Protein A Up-Regulates Activity of the Mannose Receptor, a Pattern Recognition Receptor Expressed on Human Macrophages

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A Member of the Dendritic Cell Family That Enters B Cell Follicles and Stimulates Primary Antibody Responses Identified by a Mannose Receptor Fusion Protein

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Clearance of Neutrophil-derived Myeloperoxidase by the Macrophage Mannose Receptor

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Identification and Characterization of the Endocytic Transmembrane Glycoprotein Endo180 as a Novel Collagen Receptor

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A Urokinase Receptor-associated Protein with Specific Collagen Binding Properties

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Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies

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Structure of a C-type Carbohydrate Recognition Domain from the Macrophage Mannose Receptor

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A Functional Soluble Form of the Murine Mannose Receptor Is Produced by Macrophages in Vitro and Is Present in Mouse Serum

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Pneumocystis carinii glycoprotein A binds macrophage mannose receptors

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B Cells Control the Migration of a Subset of Dendritic Cells into B Cell Follicles Via CXC Chemokine Ligand 13 in a Lymphotoxin-Dependent Fashion

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Expression of a mannose/fucose membrane lectin on human dendritic cells

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Crystal Structure of the Cysteine-Rich Domain of Mannose Receptor Complexed with a Sulfated Carbohydrate Ligand

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Mannose Receptor Targeting of Tumor Antigen pmel17 to Human Dendritic Cells Directs Anti-Melanoma T Cell Responses via Multiple HLA Molecules

Ramakrishna, V., Treml, J., Vitale, L. A., Connolly, J. E., O’Neill, T. J., Smith, P. A., Jones, C. L., He, L.-Z., Goldstein, J., Wallace, P. K., et al. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.5.2845 · Cited by 114 · see citing works

Pulmonary Collectins Enhance Phagocytosis of Mycobacterium avium through Increased Activity of Mannose Receptor

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Absence of the Macrophage Mannose Receptor in Mice Does Not Increase Susceptibility toPneumocystis cariniiInfection In Vivo

Swain, S. D., Lee, S. J., Nussenzweig, M. C., & Harmsen, A. G. (2003) · Infection and Immunity · doi:10.1128/iai.71.11.6213-6221.2003 · Cited by 110 · see citing works

Binding and Uptake of Agalactosyl IgG by Mannose Receptor on Macrophages and Dendritic Cells

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Cell-specific Glycoforms of Sialoadhesin and CD45 Are Counter-receptors for the Cysteine-rich Domain of the Mannose Receptor

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Toll receptor families: structure and function

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A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake

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Mechanism of Ca2- and Monosaccharide Binding to a C-type Carbohydrate-recognition Domain of the Macrophage Mannose Receptor

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Pneumocystis Activates Human Alveolar Macrophage NF-κB Signaling through Mannose Receptors

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The role of macrophage receptors in adhesion and uptake of Leishmania mexicana amastigotes

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Characterization of a Novel Member of the Macrophage Mannose Receptor Type C Lectin Family

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Characterization of Sugar Binding by the Mannose Receptor Family Member, Endo180

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The macrophage/endothelial cell mannose receptor cDNA encodes a protein that binds oligosaccharides terminating with SO 4 -4-GalNAcβ1,4GlcNAcβ or Man at independent sites

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Binding Properties of the Mannose Receptor

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Molecular basis of lutropin recognition by the mannose/GalNAc-4-SO ₄ receptor

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Isolation and characterization of a mannose receptor from human pigment epithelium.

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A mannose receptor mediates mannosyl-rich glycoprotein-induced mitogenesis in bovine airway smooth muscle cells.

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A Di-aromatic Motif in the Cytosolic Tail of the Mannose Receptor Mediates Endosomal Sorting

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Regulation of lutropin circulatory half-life by the mannose/N-acetylgalactosamine-4-SO4 receptor is critical for implantation in vivo

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An Extended Conformation of the Macrophage Mannose Receptor

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Human dendritic cells shed a functional, soluble form of the mannose receptor

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Isolation of the SO4-4-GalNAcβ1,4GlcNAcβ1,2Manα-specific Receptor from Rat Liver

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Pneumocystis carinii enhancessoluble mannose receptor production by macrophages

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IL-4 Receptor Signaling Is Required for Mannose Receptor Expression by Macrophages Recruited to Granulomata but not Resident Cells in Mice Infected with Schistosoma mansoni

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MODULATION OF MACROPHAGE MANNOSE RECEPTOR AFFECTS THE UPTAKE OF VIRULENT AND AVIRULENTLEISHMANIA DONOVANIPROMASTIGOTES

Chakraborty, P., Ghosh, D., & Basu, M. K. (2001) · Journal of Parasitology · doi:10.1645/0022-3395(2001)087[1023:mommra]2.0.co;2 · Cited by 50 · see citing works

How is the phagocyte lectin keyboard played? Master class lesson by Mycobacterium tuberculosis

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Development of a specific system for targeting protein to metallophilic macrophages

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Multiple interactions between pituitary hormones and the mannose receptor

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Potential role of the mannose receptor in antigen transport

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Mannose Receptor Ligand-Positive Cells Express the Metalloprotease Decysin in the B Cell Follicle

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Letters to the Glyco-Forum

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Macrophage Mannosyl Fucosyl Receptor: Its Role in Invasion of Virulent and Avirulent L. Donovani Promastigotes

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Three‐dimensional interplay among the ligand‐binding domains of the urokinase‐plasminogen‐activator‐receptor‐associated protein, Endo180

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Monoclonal Antibodies against the Human Mannose Receptor that Inhibit the Binding of Tissue-type Plasminogen Activator

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The mannose receptor fails to enhance processing and presentation of a glycoprotein antigen in transfected fibroblasts

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Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

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The Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue Homeostasis

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Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

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The role of the cell wall in fungal pathogenesis

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Antitumor activity of liposomal ErbB2/HER2 epitope peptide-based vaccine constructs incorporating TLR agonists and mannose receptor targeting

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Use of lectin-functionalized particles for oral immunotherapy

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<i>Candida</i>Immunity

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A Synthetic MUC1 Anticancer Vaccine Containing Mannose Ligands for Targeting Macrophages and Dendritic Cells

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Involvement of mannose receptor in the preventive effects of mannose in lipopolysaccharide-induced acute lung injury

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Generation of Macrophage Variants With 5-Azacytidine: Selection for Mannose Receptor Expression

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Detection of Fungi by Mannose-based Recognition Receptors

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