The DOI matches its Crossref record; 134 of the 134 references it cites were found in a registry or an index.
Macrophage phenotypes and functions: resolving inflammation and restoring homeostasis
Open accessAbstract
Inflammation must be tightly regulated to both defend against pathogens and restore tissue homeostasis. The resolution of inflammatory responses is a dynamic process orchestrated by cells of the immune system. Macrophages, tissue-resident innate immune cells, are key players in modulating inflammation. Here, we review recent work highlighting the importance of macrophages in tissue resolution and the return to homeostasis. We propose that enhancing macrophage pro-resolution functions represents a novel and widely applicable therapeutic strategy to dampen inflammation, promote repair, and restore tissue integrity and function.
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Cited by
Tissue macrophages: origin, heterogenity, biological functions, diseases and therapeutic targets
Guan, F., Wang, R., Yi, Z., Luo, P., Liu, W., Xie, Y., Liu, Z., Xia, Z., Zhang, H., & Cheng, Q. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02124-y · Cited by 371
Han, X., Wu, X., Liu, F., Chen, H., & Hou, H. (2024) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2024.117942 · Cited by 21
Cao, C., Liu, W., Guo, X., Weng, S., Chen, Y., Luo, Y., Wang, S., Zhu, B., Liu, Y., & Peng, D. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1460431 · Cited by 16
Metadata
- Authors
- Rodríguez-Morales, P., & Franklin, R. A.
- Venue
- Trends in Immunology
- Publisher
- Elsevier BV
- Published
- 2023-12
- Volume
- 44
- Issue
- 12
- Pages
- 986-998
- ISSN
- 1471-4906 (ISSN-L)
- OpenAlex
- W4388406732
- Cited by
- 304
- References
- 134
- FWCI
- 9.57
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
