ACC/AHA/ASNC Guidelines for the Clinical Use of Cardiac Radionuclide Imaging—Executive Summary
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Caffeine is a nonselective competitive A2A receptor antagonist and its use has been contraindicated before vasodilator MPI because it attenuates coronary hyperemia caused by adenosine and dipyridamole in a dose-dependent manner.
“The use of caffeine, a nonselective competitive A 2A receptor antagonist, has been contraindicated before vasodilator MPI (3) because it attenuates the coronary hyperemia caused by the nonselective adenosine receptor agonists adenosine and dipyridamole in a dose-dependent manner (4).”
From Interaction of Caffeine With Regadenoson-Induced Hyperemic Myocardial Blood Flow as Measured by Positron Emission Tomography (2008) · cites this paper as [3]
The interaction of caffeine with adenosine-induced, dipyridamole-induced, and exercise-induced MBF changes may limit correct detection of coronary artery disease and proper management, leading to recommendation to withhold caffeine for 24 h before vasodilator stress testing.
“The interaction of caffeine with adenosine-induced, dipyridamoleinduced, and even exercise-induced MBF changes (4,6) may limit the correct detection of coronary artery disease and subsequently the proper management of the patient, leading to the general recommendation to withhold caffeine for 24 h before vasodilator stress testing (3).”
From Interaction of Caffeine With Regadenoson-Induced Hyperemic Myocardial Blood Flow as Measured by Positron Emission Tomography (2008) · cites this paper as [3]
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- Authors
- Klocke, F. J., Baird, M. G., Lorell, B. H., Bateman, T. M., Messer, J. V., Berman, D. S., O’Gara, P. T., Carabello, B. A., Russell, R. O., Cerqueira, M. D., St. John Sutton, M. G., DeMaria, A. N., Udelson, J. E., Kennedy, J. W., Verani, M. S., Williams, K. A., Antman, E. M., Smith, S. C., Alpert, J. S., Gregoratos, G., Anderson, J. L., Hiratzka, L. F., Faxon, D. P., Hunt, S. A., Fuster, V., Jacobs, A. K., Gibbons, R. J., & Russell, R. O.
- ORCID
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2003-10
- Volume
- 42
- Issue
- 7
- Pages
- 1318-1333
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2150815934
- Cited by
- 1,303
- References
- 64
- Citations by year
- 2026: 3 · 2025: 8 · 2024: 8 · 2023: 12 · 2022: 14 · 2021: 30 · 2020: 22 · 2019: 21 · 2018: 23 · 2017: 38 · 2016: 33 · 2015: 59 · 2014: 75 · 2013: 87 · 2012: 101
- FWCI
- 53.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Medical Imaging Techniques and Applications
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Keywords
- myocardial perfusion imaging, myocardial scintigraphy
- MeSH terms
- Coronary Artery Disease, Emergency Treatment, Heart Diseases, Heart Failure, Humans, Myocardial Infarction, Radionuclide Imaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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