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Clinical Benefits of Remote Versus Transtelephonic Monitoring of Implanted Pacemakers
Open accessAbstract
Objectives The purpose of this study was to evaluate remote pacemaker interrogation for the earlier diagnosis of clinically actionable events compared with traditional transtelephonic monitoring and routine in-person evaluation.Background Pacemaker patient follow-up procedures have evolved from evaluating devices with little programmability and diagnostic information solely in person to transtelephonic rhythm strip recordings that allow monitoring of basic device function. More recently developed remote monitoring technology leverages expanded device capabilities, augmenting traditional transtelephonic monitoring to evaluate patients via full device interrogation.Methods The time to first diagnosis of a clinically actionable event was compared in patients who were followed by remote interrogation (Remote) and those who were followed per standard of care with office visits augmented by transtelephonic monitoring (Control). Patients were randomized 2:1. Remote arm patients transmitted pacemaker information at 3-month intervals. Control arm patients with a single-chamber pacemaker transmitted at 2-month intervals. Control arm patients with dual-chamber devices transmitted at 2-month intervals with an office visit at 6 months. All patients were seen in office at 12 months.Results The mean time to first diagnosis of clinically actionable events was earlier in the Remote arm (5.7 months) than in the Control arm (7.7 months). Three (2%) of the 190 events in the Control arm and 446 (66%) of 676 events in the Remote arm were identified remotely.Conclusions The strategic use of remote pacemaker interrogation follow-up detects actionable events that are potentially important more quickly and more frequently than transtelephonic rhythm strip recordings. The use of transtelephonic rhythm strips for pacemaker follow-up is of little value except for battery status determinations. (PREFER [Pacemaker Remote Follow-up Evaluation and Review]; NCT00294645).
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“In the Pacemaker Remote Follow-up Evaluation and Review (PREFER) trial, which randomly assigned 980 PM patients to follow-up with remote monitoring versus in-office visits plus transtelephonic monitoring, clinically actionable events such as atrial arrhythmias, increase in right ventricular pacing, lead function changes, and battery depletion, were detected earlier in the remote-monitoring arm.57”
From Managing with pacemakers and implantable cardioverter defibrillators (2013) · cites this paper as [57]
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Hosoda, J., Ishikawa, T., Matsumoto, K., Kiyokuni, M., Taguchi, Y., Narikawa, M., Hibi, K., Sugano, T., Ishigami, T., Tamura, K., et al. (2020) · International Heart Journal · doi:10.1536/ihj.20-141
Sugrue, A. M., Vaidya, V. R., Hayes, D. L., Glikson, M., Friedman, P. A., & Asirvatham, S. J. (2021) · Wiley eBooks · doi:10.1002/9781119264002.ch13
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The Dropout from Remote Monitoring in CIEDs Patients
Kida, H., Kikuchi, Y., Otani, S., Aoki, R., Tamaki, S., Okada, K., Sato, N., Uenoyama, M., Kawasaki, M., Watanabe, T., et al. (2023) · Japanese Journal of Electrocardiology · doi:10.5105/jse.43.254
A scientific document for the remote monitoring of cardiac implantable electronic devices in Greece
Dilaveris, P., Antoniou, C. K., Xydonas, S., Chrysohoou, C. A., Apostolopoulos, T., Stafylas, P. C., KOCHIADAKIS, G. E., & Gatzoulis, K. A. (2025) · Hellenic Journal of Cardiology · doi:10.1016/j.hjc.2025.02.002
植込み型デバイス委員会社会問題対策委員会 植込み型心臓不整脈デバイスの遠隔モニタリングに関する日本不整脈心電学会(JHRS)ステートメント
Watanabe, E., Nishii, N., Maeda, A., Sakai, Y., Fujiu, K., Suzuki, M., Kato, R., Abe, H., Noda, T., Tada, H., et al. (2025) · Japanese Journal of Electrocardiology · doi:10.5105/jse.45.33
Tan, E. S. J., Ying, L. J., Tiong, Y. W., & Kojodjojo, P. (2026) · Indian Pacing and Electrophysiology Journal · doi:10.1016/j.ipej.2026.06.004
Metadata
- Authors
- Crossley, G. H., Chen, J., Choucair, W., Cohen, T. J., Gohn, D. C., Johnson, W. B., Kennedy, E. E., Mongeon, L. R., Serwer, G. A., Qiao, H., & Wilkoff, B. L.
- Affiliations
- University of Tennessee at Knoxville (US)
- Washington University in St. Louis (US)
- Winthrop-University Hospital (US)
- Arkansas Heart Hospital (US)
- Medtronic (United States) (US)
- University of Michigan (US)
- Cleveland Clinic (US)
- Corresponding author
- Crossley, George H.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2009-11
- Volume
- 54
- Issue
- 22
- Pages
- 2012-2019
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W1989653793
- Cited by
- 202
- References
- 19
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 2 · 2023: 11 · 2022: 5 · 2021: 13 · 2020: 12 · 2019: 9 · 2018: 11 · 2017: 11 · 2016: 14 · 2015: 18 · 2014: 11 · 2013: 27 · 2012: 27
- FWCI
- 11.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Medtronic
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › ECG Monitoring and Analysis
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
- Keywords
- transtelephonic monitoring, implantable pacemaker, pacemaker follow-up, time to diagnosis, remote monitoring, device interrogation, battery status, single-chamber pacemaker, dual-chamber pacemaker
- MeSH terms
- Aged, Aged, 80 and over, Arrhythmias, Cardiac, Coronary Artery Disease, Diabetic Angiopathies, Female, Heart Failure, Humans, Male, Middle Aged, Monitoring, Physiologic, Office Visits, Pacemaker, Artificial, Prospective Studies, Telemetry, Telephone, Time Factors, Comorbidity
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