Cited by 2,906Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) ResearchOccupational exposure and asthma

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Development of the asthma control test

Nathan, Robert A, Sorkness, Christine A, Kosinski, Mark, Schatz, Michael, Li, James T, Marcus, Philip, Murray, John J, Pendergraft, Trudy B·2004·Journal of Allergy and Clinical Immunology

DOI 10.1016/j.jaci.2003.09.008

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Abstract

Background Asthma guidelines indicate that the goal of treatment should be optimum asthma control. In a busy clinic practice with limited time and resources, there is need for a simple method for assessing asthma control with or without lung function testing. Objectives The objective of this article was to describe the development of the Asthma Control Test (ACT), a patient-based tool for identifying patients with poorly controlled asthma. Methods A 22-item survey was administered to 471 patients with asthma in the offices of asthma specialists. The specialist's rating of asthma control after spirometry was also collected. Stepwise regression methods were used to select a subset of items that showed the greatest discriminant validity in relation to the specialist's rating of asthma control. Internal consistency reliability was computed, and discriminant validity tests were conducted for ACT scale scores. The performance of ACT was investigated by using logistic regression methods and receiver operating characteristic analyses. Results Five items were selected from regression analyses. The internal consistency reliability of the 5-item ACT scale was 0.84. ACT scale scores discriminated between groups of patients differing in the specialist's rating of asthma control (F = 34.5, P Conclusion Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma control.

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Authors: Nathan, R. A., Sorkness, C. A., Kosinski, M., Schatz, M., Li, J. T., Marcus, P., Murray, J. J., & Pendergraft, T. B.
Affiliations: University of Wisconsin–Madison (US)
Kaiser Permanente (US)
Mayo Clinic (US)
Great Falls Clinic (US)
Vanderbilt University Medical Center (US)
GlaxoSmithKline (United States) (US)
ORCID: Sorkness, Christine A
Kosinski, Mark
Schatz, Michael
Murray, John J
Venue: Journal of Allergy and Clinical Immunology
Publisher: Elsevier BV
Published: 2004-01
Volume: 113
Issue: 1
Pages: 59-65
ISSN: 0091-6749 (ISSN-L)
DOI: 10.1016/j.jaci.2003.09.008
OpenAlex: W2616424562
Cited by: 2,906
References: 13
Citations by year: 2026: 141 · 2025: 163 · 2024: 189 · 2023: 172 · 2022: 186 · 2021: 204 · 2020: 219 · 2019: 166 · 2018: 149 · 2017: 157 · 2016: 135 · 2015: 137 · 2014: 131 · 2013: 150 · 2012: 112
FWCI: 24.87
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Journal of Allergy and Clinical Immunology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
Keywords: Asthma Control Test, asthma control, patient-reported outcome measures, asthma screening, FEV1, discriminant validity, internal consistency, treatment needs assessment
MeSH terms: Adolescent, Adult, Aged, Asthma, False Positive Reactions, Health Surveys, Humans, Middle Aged, Predictive Value of Tests, Surveys and Questionnaires, Sensitivity and Specificity, Severity of Illness Index, Spirometry, Reproducibility of Results, Outcome Assessment, Health Care

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