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Hereditary and acquired angioedema: Problems and progress: Proceedings of the third C1 esterase inhibitor deficiency workshop and beyond

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Agostoni, Angelo, Aygören-Pürsün, Emel, Binkley, Karen E., Blanch, Alvaro, Bork, Konrad, Bouillet, Laurence, Bucher, Christoph, Castaldo, Anthony J, Cicardi, Marco, Davis, Alvin E, De Carolis, Caterina, Drouet, Christian, Duponchel, Christiane, Farkas, Henriette, Fáy, Kálmán, Fekete, Béla, Fischer, Bettina, Fontana, Luigi, Füst, George, Giacomelli, Roberto, Gröner, Albrecht, Erik Hack, C., Harmat, George, Jakenfelds, John, Juers, Mathias, Kalmár, Lajos, Kaposi, Pál N., Karádi, István, Kitzinger, Arianna, Kollár, Tímea, Kreuz, Wolfhart, Lakatos, Peter, Longhurst, Hilary J., Lopez-Trascasa, Margarita, Martinez-Saguer, Inmaculada, Monnier, Nicole, Nagy, István, Németh, Éva, Nielsen, Erik Waage, Nuijens, Jan H., O'Grady, Caroline, Pappalardo, Emanuela, Penna, Vincenzo, Perricone, Carlo, Perricone, Roberto, Rauch, Ursula, Roche, Olga, Rusicke, Eva, Späth, Peter J, Szendei, George, Takács, Edit, Tordai, Attila, Truedsson, Lennart, Varga, Lilian, Visy, Beáta, Williams, Kayla, Zanichelli, Andrea, Zingale, Lorenza·2004·Journal of Allergy and Clinical Immunology
DOI 10.1016/j.jaci.2004.06.047
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Abstract

Hereditary angioedema (HAE), a rare but life-threatening condition, manifests as acute attacks of facial, laryngeal, genital, or peripheral swelling or abdominal pain secondary to intra-abdominal edema. Resulting from mutations affecting C1 esterase inhibitor (C1-INH), inhibitor of the first complement system component, attacks are not histamine-mediated and do not respond to antihistamines or corticosteroids. Low awareness and resemblance to other disorders often delay diagnosis; despite availability of C1-INH replacement in some countries, no approved, safe acute attack therapy exists in the United States. The biennial C1 Esterase Inhibitor Deficiency Workshops resulted from a European initiative for better knowledge and treatment of HAE and related diseases. This supplement contains work presented at the third workshop and expanded content toward a definitive picture of angioedema in the absence of allergy. Most notably, it includes cumulative genetic investigations; multinational laboratory diagnosis recommendations; current pathogenesis hypotheses; suggested prophylaxis and acute attack treatment, including home treatment; future treatment options; and analysis of patient subpopulations, including pediatric patients and patients whose angioedema worsened during pregnancy or hormone administration. Causes and management of acquired angioedema and a new type of angioedema with normal C1-INH are also discussed. Collaborative patient and physician efforts, crucial in rare diseases, are emphasized. This supplement seeks to raise awareness and aid diagnosis of HAE, optimize treatment for all patients, and provide a platform for further research in this rare, partially understood disorder.

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  1. Dennehy, 1970, Hereditary angioneurotic edema: report of a large kindred with defect in C'1 esterase inhibitor and review of the literature, Ann Intern Med, 73, 55, 10.7326/0003-4819-73-1-55 · doi:10.7326/0003-4819-73-1-55
  2. Milton, 1876, On giant urticaria, Edinburgh Med J, 22, 513
  3. Quincke, 1882, Über akutes umschriebenes Hautödem [About an acute described skin edema], Monatshe Prakt Dermatol, 1, 129
  4. Osler, 1888, Hereditary angio-neurotic oedema, Am J Med Sci, 95, 362, 10.1097/00000441-188804000-00004 · DOI · Paper page
  5. Donaldson, 1963, A biochemical abnormality in hereditary angioneurotic edema: absence of serum inhibitor of C' 1-esterase, Am J Med, 35, 37, 10.1016/0002-9343(63)90162-1 · DOI · Paper page
  6. Agostoni, 1992, Hereditary and acquired C1-inhibitor deficiency: biological and clinical characteristics in 235 patients, Medicine (Baltimore), 71, 206, 10.1097/00005792-199207000-00003 · DOI · Paper page
  7. Binkley, 2000, Clinical, biochemical, and genetic characterization of a novel estrogen-dependent inherited form of angioedema, J Allergy Clin Immunol, 106, 546, 10.1067/mai.2000.108106 · DOI · Paper page
  8. Han, 2002, Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptor, J Clin Invest, 109, 1057, 10.1172/JCI200214211 · DOI
  9. Luong, 1997, Complement abnormalities with lower extremities discomfort in Vietnamese immigrants, Allergy Asthma Proc, 18, 239, 10.2500/108854197778594098 · doi:10.2500/108854197778594098
  10. Donaldson, 1977, Role of the second component of complement (C2) and plasmin in kinin release in hereditary angioneurotic edema (H.A.N.E.) plasma, Trans Assoc Am Physicians, 90, 174
  11. Fields, 1983, Kinin formation in hereditary angioedema plasma: evidence against kinin derivation from C2 and in support of “spontaneous” formation of bradykinin, J Allergy Clin Immunol, 72, 54, 10.1016/0091-6749(83)90052-0 · DOI · Paper page
  12. Nussberger, 2002, Bradykinin-mediated angioedema, N Engl J Med, 347, 621, 10.1056/NEJM200208223470820 · DOI · Paper page
  13. Davis, 2003, The pathogenesis of hereditary angioedema, Transfus Apheresis Sci, 29, 195, 10.1016/j.transci.2003.08.012 · DOI
  14. Cugno, 1996, Activation of factor XII and cleavage of high molecular weight kininogen during acute attacks in hereditary and acquired C1-inhibitor deficiencies, Immunopharmacology, 33, 361, 10.1016/0162-3109(96)00086-0 · DOI
  15. Bossi, 2004, Endothelial cells contribute to vascular leakage in patients with C1 inhibitor deficiency and angioedema, Mol Immunol, 41, 212
  16. Joseph, 2002, Heat shock protein 90 catalyzes activation of the prekallikrein-kininogen complex in the absence of factor XII, Proc Natl Acad Sci U S A, 99, 896, 10.1073/pnas.022626899 · DOI
  17. Joseph, 2002, Activation of the bradykinin-forming cascade on endothelial cells: a role for heat shock protein 90, Int Immunopharmacol, 2, 1851, 10.1016/S1567-5769(02)00186-8 · DOI
  18. Andre, 2003, Exogenous oestrogen as an alternative to food allergy in the aetiology of angioneurotic oedema, Toxicology, 185, 155, 10.1016/S0300-483X(02)00584-X · DOI
  19. Yip, 1992, Hormonally exacerbated hereditary angioedema, Australas J Dermatol, 33, 35, 10.1111/j.1440-0960.1992.tb00050.x · DOI
  20. Frank, 1979, Effect of sex hormones on the complement-related clinical disorder of hereditary angioedema, Arthritis Rheum, 22, 1295, 10.1002/art.1780221118 · doi:10.1002/art.1780221118
  21. Boeckers, 1987, [Contraception and pregnancy in hereditary angioedema], Dtsch Med Wochenschr, 112, 507
  22. Wautier, 1986, [Norgestrienone, a possible therapeutic agent in hereditary angioneurotic edema], Presse Med, 15, 2023
  23. Nielsen, 1996, Hereditary angio-oedema: new clinical observations and autoimmune screening, complement and kallikrein-kinin analyses, J Intern Med, 239, 119, 10.1046/j.1365-2796.1996.418764000.x · doi:10.1046/j.1365-2796.1996.418764000.x
  24. Laurent, 1987, [Hereditary angioneurotic edema: norgestrienone is not effective in every case], Presse Med, 16, 2132
  25. Barbieri, 1981, Danazol: endocrine pharmacology and therapeutic applications, Am J Obstet Gynecol, 141, 453, 10.1016/0002-9378(81)90611-6 · DOI · Paper page
  26. Hadjiyannaki, 1971, Hereditary angio-oedema: a review with particular reference to pathogenesis and treatment, Clin Allergy, 1, 221, 10.1111/j.1365-2222.1971.tb03021.x · doi:10.1111/j.1365-2222.1971.tb03021.x
  27. Nussberger, 1999, Local bradykinin generation in hereditary angioedema, J Allergy Clin Immunol, 104, 1321, 10.1016/S0091-6749(99)70030-8 · DOI
  28. Zahedi, 1997, Role of the P2 residue of complement 1 inhibitor (Ala443) in determination of target protease specificity: inhibition of complement and contact system proteases, J Immunol, 159, 983, 10.4049/jimmunol.159.2.983 · DOI
  29. Venema, 2002, Post-translational mechanisms of endothelial nitric oxide synthase regulation by bradykinin, Int Immunopharmacol, 2, 1755, 10.1016/S1567-5769(02)00185-6 · DOI
  30. Kaplan, 2002, Pathways for bradykinin formation and inflammatory disease, J Allergy Clin Immunol, 109, 195, 10.1067/mai.2002.121316 · DOI · Paper page
  31. Frank, 1976, Hereditary angioedema: the clinical syndrome and its management, Ann Intern Med, 84, 580, 10.7326/0003-4819-84-5-580 · DOI · Paper page
  32. Winnewisser, 1997, Type I hereditary angio-oedema: variability of clinical presentation and course within two large kindreds, J Intern Med, 241, 39, 10.1046/j.1365-2796.1997.76893000.x · doi:10.1046/j.1365-2796.1997.76893000.x
  33. Cicardi, 1998, Pathogenetic and clinical aspects of C1 inhibitor deficiency, Immunobiology, 199, 366, 10.1016/S0171-2985(98)80041-7 · DOI
  34. Bork, 1998, [Hypovolemic shock caused by ascites in hereditary angioedema], Med Klin (Munich), 93, 554, 10.1007/BF03042666 · doi:10.1007/bf03042666
  35. Cohen, 1993, Hereditary angioneurotic edema with severe hypovolemic shock, J Clin Gastroenterol, 16, 237, 10.1097/00004836-199304000-00016 · doi:10.1097/00004836-199304000-00016
  36. Talavera, 1995, Hereditary angioedema: an infrequent cause of abdominal pain with ascites, Am J Gastroenterol, 90, 471
  37. Dinkel, 2001, Sonographic appearances of the abdominal manifestations of hereditary angioedema, Pediatr Radiol, 31, 296, 10.1007/s002470000409 · doi:10.1007/s002470000409
  38. Campanile, 2001, Changes in splenoportal axis calibre and flow in a patient affected by hereditary angioedema, Panminerva Med, 43, 307
  39. Sofia, 1999, Sonographic findings in abdominal hereditary angioedema, J Clin Ultrasound, 27, 537, 10.1002/(SICI)1097-0096(199911/12)27:9<537::AID-JCU9>3.0.CO;2-L · doi:10.1002/(sici)1097-0096(199911/12)27:9<537::aid-jcu9>3.0.co;2-l
  40. De Backer, 2001, CT of angioedema of the small bowel, AJR Am J Roentgenol, 176, 649, 10.2214/ajr.176.3.1760649 · DOI
  41. Wong, 1999, Image of the month: hereditary angioedema (HAE), Gastroenterology, 116, 514, 10.1016/S0016-5085(99)70170-8 · doi:10.1016/s0016-5085(99)70170-8
  42. Hara, 1999, Hereditary angioedema with gastrointestinal involvement: endoscopic appearance, Endoscopy, 31, 322, 10.1055/s-1999-14 · doi:10.1055/s-1999-14
  43. Calbo, 1992, Abdominal attack of hereditary angioedema associated with marked leucocytosis: a case report, Ital J Gastroenterol, 24, 464
  44. Wüthrich, 1999, [Hereditary or acquired angioedema caused by functional deficiency of C1 inhibitor–a still unfamiliar disease picture], Schweiz Med Wochenschr, 129, 285
  45. Bork, 2000, Asphyxiation by laryngeal edema in patients with hereditary angioedema, Mayo Clin Proc, 75, 349, 10.4065/75.4.349 · doi:10.4065/75.4.349
  46. Bork, 2001, Treatment of 193 episodes of laryngeal edema with C1 inhibitor concentrate in patients with hereditary angioedema, Arch Intern Med, 161, 714, 10.1001/archinte.161.5.714 · doi:10.1001/archinte.161.5.714
  47. Farkas, 2001, Erythema marginatum preceding an acute oedematous attack of hereditary angioneurotic oedema, Acta Derm Venereol, 81, 376, 10.1080/000155501317140188 · doi:10.1080/000155501317140188
  48. Legendre, 1985, [Respiratory manifestations in hereditary angioneurotic edema], Rev Pneumol Clin, 41, 251
  49. Van Dellen, 1980, Bladder involvement in hereditary angioedema, Mayo Clin Proc, 55, 277
  50. Sunder, 1982, Neurological manifestations of angioedema: report of two cases and review of the literature, JAMA, 247, 2005, 10.1001/jama.1982.03320390067048 · doi:10.1001/jama.1982.03320390067048
  51. Krause, 1979, [Cerebral manifestations in angioneurotic edema (author's translation)], J Neurol Sci, 42, 429, 10.1016/0022-510X(79)90175-8 · doi:10.1016/0022-510x(79)90175-8
  52. Landerman, 1962, Hereditary angioneurotic edema, I: case reports and review of the literature, J Allergy, 33, 316, 10.1016/0021-8707(62)90031-X · doi:10.1016/0021-8707(62)90031-x
  53. Bonner, 1990, Hemodynamic effects of bradykinin on systemic and pulmonary circulation in healthy and hypertensive humans, J Cardiovasc Pharmacol, 15, S46, 10.1097/00005344-199015061-00010 · DOI
  54. Lung, 1997, Analysis of an exon 1 polymorphism of the B2 bradykinin receptor gene and its transcript in normal subjects and patients with C1 inhibitor deficiency, J Allergy Clin Immunol, 99, 134
  55. Farkas, 2001, Eradication of Helicobacter pylori and improvement of hereditary angioneurotic oedema, Lancet, 358, 1695, 10.1016/S0140-6736(01)06720-4 · doi:10.1016/s0140-6736(01)06720-4
  56. Iamandescu, 1990, Contributions to the study of the favouring role of chronic urinary infections in inducing and starting drug-allergic-type reactions, Med Interne, 28, 53
  57. Watson, 2000, Acquired angioedema associated with sinusitis, J Investig Allergol Clin Immunol, 10, 129
  58. Wedi, 1999, Helicobacter pylori infection and skin diseases, J Physiol Pharmacol, 50, 753
  59. Gudat, 1989, Hereditary angioedema associated with subacute cutaneous lupus erythematosus, Dermatologica, 179, 211, 10.1159/000248363 · doi:10.1159/000248363
  60. Duncan, 1988, Rheumatoid arthritis and hereditary angioedema, J Rheumatol, 15, 700
  61. Brickman, 1986, Immunoregulatory disorders associated with hereditary angioedema, I: clinical manifestations of autoimmune disease, J Allergy Clin Immunol, 77, 749, 10.1016/0091-6749(86)90424-0 · DOI
  62. Brickman, 1986, Immunoregulatory disorders associated with hereditary angioedema, II: serologic and cellular abnormalities, J Allergy Clin Immunol, 77, 758, 10.1016/0091-6749(86)90425-2 · doi:10.1016/0091-6749(86)90425-2
  63. Koide, 2002, Lupus erythematosus associated with C1 inhibitor deficiency, J Dermatol, 29, 503, 10.1111/j.1346-8138.2002.tb00316.x · DOI
  64. Sturfelt, 1996, C1 inhibitor deficiency in a patient with rheumatoid arthritis—increased risk of adverse effects of penicillamine?, J Rheumatol, 23, 378
  65. Hory, 1989, Glomerulonephritis and hereditary angioedema: report of 2 cases, Clin Nephrol, 31, 259
  66. Ley, 1987, A family with hereditary angioedema and multiple immunologic disorders, Am J Med, 82, 1046, 10.1016/0002-9343(87)90173-2 · DOI
  67. Agnello, 1978, Association of systemic lupus erythematosus and SLE-like syndromes with hereditary and acquired complement deficiency states, Arthritis Rheum, 21, S146, 10.1002/art.1780210923 · DOI
  68. Pan, 1992, Long-term follow-up of non-systemic lupus erythematosus glomerulonephritis in patients with hereditary angioedema: report of four cases, Am J Kidney Dis, 19, 526, 10.1016/S0272-6386(12)80830-4 · doi:10.1016/s0272-6386(12)80830-4
  69. Suzuki, 1986, A case of hereditary angioneurotic edema associated with systemic lupus erythematosus, Jpn J Med, 25, 281, 10.2169/internalmedicine1962.25.281 · DOI
  70. Alper, 1987, Inherited deficiencies of complement components in man, Immunol Lett, 14, 175, 10.1016/0165-2478(87)90098-8 · doi:10.1016/0165-2478(87)90098-8
  71. Fernandez, 1978, Hereditary angioneurotic edema and Charcot-Marie-Tooth disease in the same family, Can Med Assoc J, 119, 455
  72. Christie, 1997, Association of hereditary angioedema and hereditary breast cancer, Cancer Genet Cytogenet, 95, 159, 10.1016/S0165-4608(96)00218-X · DOI
  73. Farkas, 2002, Association of celiac disease and hereditary angioneurotic edema, Am J Gastroenterol, 97, 2682, 10.1111/j.1572-0241.2002.06059.x · doi:10.1111/j.1572-0241.2002.06059.x
  74. Farkas, 1999, Coincidence of hereditary angioedema (HAE) with Crohn's disease, Immunol Invest, 28, 43, 10.3109/08820139909022722 · doi:10.3109/08820139909022722
  75. Cicardi, 1995, Reduction in transmission of hepatitis C after the introduction of a heat-treatment step in the production of C1-inhibitor concentrate, Transfusion, 35, 209, 10.1046/j.1537-2995.1995.35395184276.x · doi:10.1046/j.1537-2995.1995.35395184276.x
  76. Laurent, 1988, Ultrasonography in the diagnosis of hereditary angioneurotic oedema, Lancet, 1, 761, 10.1016/S0140-6736(88)91558-9 · doi:10.1016/s0140-6736(88)91558-9
  77. Burghardt, 1987, Ultrasonography for early diagnosis of hereditary angioneurotic oedema, Lancet, 2, 165, 10.1016/S0140-6736(87)92371-3 · doi:10.1016/s0140-6736(87)92371-3
  78. Farkas, 2001, Ultrasonography in the diagnosis and monitoring of ascites in acute abdominal attacks of hereditary angioneurotic oedema, Eur J Gastroenterol Hepatol, 13, 1225, 10.1097/00042737-200110000-00016 · doi:10.1097/00042737-200110000-00016
  79. Farkas, 2002, Clinical management of hereditary angio-oedema in children, Pediatr Allergy Immunol, 13, 153, 10.1034/j.1399-3038.2002.01014.x · doi:10.1034/j.1399-3038.2002.01014.x
  80. Farkas, 2002, Acute abdominal attack of hereditary angioneurotic oedema associated with ultrasound abnormalities suggestive of acute hepatitis, Acta Paediatr, 91, 971, 10.1111/j.1651-2227.2002.tb02864.x · doi:10.1111/j.1651-2227.2002.tb02864.x
  81. Greaves, 1991, Angioedema: manifestations and management, J Am Acad Dermatol, 25, 155, 10.1016/0190-9622(91)70183-3 · DOI
  82. Nzeako, 2001, Hereditary angioedema: a broad review for clinicians, Arch Intern Med, 161, 2417, 10.1001/archinte.161.20.2417 · DOI · Paper page
  83. Zuraw, 2000, Detection of C1 inhibitor mutations in patients with hereditary angioedema, J Allergy Clin Immunol, 105, 541, 10.1067/mai.2000.104780 · DOI
  84. Bowen, 2001, A review of the reported defects in the human C1 esterase inhibitor gene producing hereditary angioedema including four new mutations, Clin Immunol, 98, 157, 10.1006/clim.2000.4947 · doi:10.1006/clim.2000.4947
  85. Bork, 2000, Hereditary angioedema with normal C1-inhibitor activity in women, Lancet, 356, 213, 10.1016/S0140-6736(00)02483-1 · DOI · Paper page
  86. Martin, 2001, Hereditary angioedema type III: an additional French pedigree with autosomal dominant transmission, J Allergy Clin Immunol, 107, 747, 10.1067/mai.2001.114242 · doi:10.1067/mai.2001.114242
  87. Rosen, 1965, Hereditary angioneurotic edema: two genetic variants, Science, 148, 957, 10.1126/science.148.3672.957 · DOI · Paper page
  88. Davis, 1988, C1 inhibitor and hereditary angioneurotic edema, Annu Rev Immunol, 6, 595, 10.1146/annurev.iy.06.040188.003115 · doi:10.1146/annurev.iy.06.040188.003115 · Paper page
  89. Quastel, 1983, Behavior in vivo of normal and dysfunctional C1 inhibitor in normal subjects and patients with hereditary angioneurotic edema, J Clin Invest, 71, 1041, 10.1172/JCI110831 · DOI
  90. Verpy, 1995, Crucial residues in the carboxy-terminal end of C1 inhibitor revealed by pathogenic mutants impaired in secretion or function, J Clin Invest, 95, 350, 10.1172/JCI117663 · doi:10.1172/jci117663
  91. Binkley, 2003, Estrogen-dependent inherited angioedema, Transfus Apheresis Sci, 29, 215, 10.1016/j.transci.2003.08.002 · doi:10.1016/j.transci.2003.08.002
  92. Decarie, 1996, Serum interspecies differences in metabolic pathways of bradykinin and [des-Arg9]BK: influence of enalaprilat, Am J Physiol, 271, H1340
  93. Blais, 1999, Des-Arg9-bradykinin metabolism in patients who presented hypersensitivity reactions during hemodialysis: role of serum ACE and aminopeptidase P, Peptides, 20, 421, 10.1016/S0196-9781(99)00020-0 · DOI · Paper page
  94. Adam, 2002, Aminopeptidase P in individuals with a history of angio-oedema on ACE inhibitors, Lancet, 359, 2088, 10.1016/S0140-6736(02)08914-6 · DOI · Paper page
  95. Shepherd, 1990, Possible contraindication of angiotensin converting enzyme inhibitors in patients with hereditary angioedema, Am J Med, 88, 446, 10.1016/0002-9343(90)90514-E · DOI
  96. Binkley, 1996, Exacerbation of angioedema by an angiotensin converting enzyme inhibitor in a patient with variant form hereditary angioedema, Can J Allergy Clin Immunol, 1, 134
  97. Berkun, 2001, Hereditary angioedema first apparent in the ninth decade during treatment with ACE inhibitor, Ann Allergy Asthma Immunol, 87, 138, 10.1016/S1081-1206(10)62208-9 · DOI
  98. Binkley, 2001, Reply (Hereditary angioedema type III: an additional French pedigree with autosomal dominant transmission), J Allergy Clin Immunol, 107, 747, 10.1067/mai.2001.114243 · doi:10.1067/mai.2001.114243
  99. Kranke, 2000, Hereditary angioedema and normal C1-inhibitor activity in women, Lancet, 356, 1440, 10.1016/S0140-6736(05)74078-2 · doi:10.1016/s0140-6736(05)74078-2
  100. Spaulding, 1960, Methyltestosterone therapy for hereditary episodic edema (hereditary angioneurotic edema), Ann Intern Med, 53, 739, 10.7326/0003-4819-53-4-739 · DOI · Paper page
  101. Gelfand, 1979, Acquired C1 esterase inhibitor deficiency and angioedema: a review, Medicine (Baltimore), 58, 321, 10.1097/00005792-197907000-00004 · DOI · Paper page
  102. Sheffer, 1987, Hereditary angioedema: a decade of management with stanozolol, J Allergy Clin Immunol, 80, 855, 10.1016/S0091-6749(87)80277-4 · doi:10.1016/s0091-6749(87)80277-4
  103. Gordon, 1980, Rapid fibrinolysis, augmented Hageman factor (factor XII) titers, and decreased C1 esterase inhibitor titers in women taking oral contraceptives, J Lab Clin Med, 96, 762
  104. Ogston, 1981, C1 inactivator level in pregnancy, Thromb Res, 23, 453, 10.1016/0049-3848(81)90206-1 · doi:10.1016/0049-3848(81)90206-1
  105. Halbmayer, 1991, C1-esterase inhibitor in uncomplicated pregnancy and mild and moderate preeclampsia, Thromb Haemost, 65, 134, 10.1055/s-0038-1647471 · doi:10.1055/s-0038-1647471
  106. Cohen, 1992, C1 esterase inhibitor in pregnancy, J Allergy Clin Immunol, 90, 412, 10.1016/S0091-6749(05)80025-9 · doi:10.1016/s0091-6749(05)80025-9
  107. Caldwell, 1972, Acquired C1 inhibitor deficiency in lymphosarcoma, Clin Immunol Immunopathol, 1, 39, 10.1016/0090-1229(72)90006-2 · DOI · Paper page
  108. Melamed, 1986, The metabolism of C1 inhibitor and C1q in patients with acquired C1-inhibitor deficiency, J Allergy Clin Immunol, 77, 322, 10.1016/S0091-6749(86)80111-7 · doi:10.1016/s0091-6749(86)80111-7
  109. Spath, 1989, Acquired angioedema and anti-C1-inhibitor autoantibody, Arch Intern Med, 149, 1213, 10.1001/archinte.1989.00390050159036 · DOI
  110. Cicardi, 1993, Autoimmune C1 inhibitor deficiency: report of eight patients, Am J Med, 95, 169, 10.1016/0002-9343(93)90257-P · doi:10.1016/0002-9343(93)90257-p
  111. Cicardi, 1996, Relevance of lymphoproliferative disorders and of anti-C1 inhibitor autoantibodies in acquired angio-oedema, Clin Exp Immunol, 106, 475, 10.1046/j.1365-2249.1996.d01-866.x · DOI
  112. Schreiber, 1976, Acquired angioedema with lymphoproliferative disorder: association of C1 inhibitor deficiency with cellular abnormality, Blood, 48, 567, 10.1182/blood.V48.4.567.567 · DOI
  113. Hauptmann, 1979, Acquired C1 inhibitor deficiency in a case of lymphosarcoma of the spleen: reversal of complement abnormalities after splenectomy, Clin Exp Immunol, 37, 523
  114. Cicardi, 1985, Acquired C1 inhibitor deficiency with angioedema symptoms in a patient infected with Echinococcus granulosus, Complement, 2, 133, 10.1159/000467853 · doi:10.1159/000467853
  115. Farkas, 1999, Acquired angioedema associated with chronic hepatitis C, J Allergy Clin Immunol, 103, 711, 10.1016/S0091-6749(99)70248-4 · doi:10.1016/s0091-6749(99)70248-4
  116. Farkas, 1999, Angioedema due to acquired C1-esterase inhibitor deficiency in a patient with Helicobacter pylori infection, Z Gastroenterol, 37, 513
  117. Farkas, 2001, Angiooedema due to acquired deficiency of C1-esterase inhibitor associated with leucocytoclastic vasculitis, Acta Derm Venereol, 81, 298, 10.1080/00015550152572985 · doi:10.1080/00015550152572985
  118. Sheffer, 1985, Acquired deficiency of the inhibitor of the first component of complement: report of five additional cases with commentary on the syndrome, J Allergy Clin Immunol, 75, 640, 10.1016/0091-6749(85)90087-9 · doi:10.1016/0091-6749(85)90087-9
  119. Pascual, 1987, Recurrent febrile panniculitis and hepatitis in two patients with acquired complement deficiency and paraproteinemia, Am J Med, 83, 959, 10.1016/0002-9343(87)90659-0 · doi:10.1016/0002-9343(87)90659-0
  120. Nakamura, 1991, Acquired C1 inhibitor deficiency associated with systemic lupus erythematosus affecting the central nervous system, Ann Rheum Dis, 50, 713, 10.1136/ard.50.10.713 · DOI
  121. Barilla-LaBarca, 2002, Acquired C1 esterase inhibitor deficiency in two patients presenting with a lupus-like syndrome and anticardiolipin antibodies, Arthritis Rheum, 47, 223, 10.1002/art.10342 · DOI
  122. Frigas, 1989, Angioedema with acquired deficiency of the C1 inhibitor: a constellation of syndromes, Mayo Clin Proc, 64, 1269, 10.1016/S0025-6196(12)61290-7 · doi:10.1016/s0025-6196(12)61290-7
  123. Jackson, 1986, An IgG autoantibody which inactivates C1-inhibitor, Nature, 323, 722, 10.1038/323722a0 · DOI · Paper page
  124. Jackson, 1989, Autoantibody facilitated cleavage of C1-inhibitor in autoimmune angioedema, J Clin Invest, 83, 698, 10.1172/JCI113934 · DOI
  125. Alsenz, 1989, Acquired C1 inhibitor (C1-INH) deficiency type II: replacement therapy with C1-INH and analysis of patients' C1-INH and anti-C1-INH autoantibodies, J Clin Invest, 83, 1794, 10.1172/JCI114084 · doi:10.1172/jci114084
  126. Whaley, 1996, Autoimmune C1-inhibitor deficiency, Clin Exp Immunol, 106, 423, 10.1046/j.1365-2249.1996.d01-879.x · doi:10.1046/j.1365-2249.1996.d01-879.x
  127. D'Incan, 1999, Acquired angioedema with C1 inhibitor deficiency: is the distinction between type I and type II still relevant?, Dermatology, 199, 227, 10.1159/000018252 · doi:10.1159/000018252
  128. Fremeaux-Bacchi, 2002, Prevalence of monoclonal gammopathy in patients presenting with acquired angioedema type 2, Am J Med, 113, 194, 10.1016/S0002-9343(02)01124-5 · doi:10.1016/s0002-9343(02)01124-5
  129. Bouillet-Claveyrolas, 2003, Clinical and biological distinctions between type I and type II acquired angioedema, Am J Med, 115, 420, 10.1016/S0002-9343(03)00396-6 · doi:10.1016/s0002-9343(03)00396-6
  130. Cicardi, 2003, Autoantibodies and lymphoproliferative diseases in acquired C1-inhibitor deficiencies, Medicine (Baltimore), 82, 274, 10.1097/01.md.0000085055.63483.09 · doi:10.1097/01.md.0000085055.63483.09
  131. Cicardi, 1999, Idiopathic nonhistaminergic angioedema, Am J Med, 106, 650, 10.1016/S0002-9343(99)00123-0 · DOI
  132. Irons, 2003, Valsartan-induced angioedema, Ann Pharmacother, 37, 1024, 10.1345/aph.1C520 · DOI
  133. Spath, 1984, Quantification of C1-inhibitor functional activities by immunodiffusion assay in plasma of patients with hereditary angioedema—evidence of a functionally critical level of C1-inhibitor concentration, Complement, 1, 147, 10.1159/000467830 · DOI
  134. Sim, 1979, Interaction of 125I-labelled complement subcomponents C-1r and C-1s with protease inhibitors in plasma, FEBS Lett, 97, 111, 10.1016/0014-5793(79)80063-0 · doi:10.1016/0014-5793(79)80063-0
  135. de Agostini, 1984, Inactivation of factor XII active fragment in normal plasma: predominant role of C-1-inhibitor, J Clin Invest, 73, 1542, 10.1172/JCI111360 · doi:10.1172/jci111360
  136. Harpel, 1985, Distribution of plasma kallikrein between C-1 inactivator and alpha 2-macroglobulin in plasma utilizing a new assay for alpha 2-macroglobulin-kallikrein complexes, J Biol Chem, 260, 4257, 10.1016/S0021-9258(18)89258-4 · DOI
  137. Huisman, 1995, On the role of C1-inhibitor as inhibitor of tissue-type plasminogen activator in human plasma, Thromb Haemost, 73, 466, 10.1055/s-0038-1653798 · DOI
  138. Wuillemin, 1995, Inactivation of factor XIa in human plasma assessed by measuring factor XIa-protease inhibitor complexes: major role for C1-inhibitor, Blood, 85, 1517, 10.1182/blood.V85.6.1517.bloodjournal8561517 · DOI
  139. Matsushita, 2000, Proteolytic activities of two types of mannose-binding lectin-associated serine protease, J Immunol, 165, 2637, 10.4049/jimmunol.165.5.2637 · DOI · Paper page
  140. Potempa, 1994, The serpin superfamily of proteinase inhibitors: structure, function, and regulation, J Biol Chem, 269, 15957, 10.1016/S0021-9258(17)33954-6 · DOI · Paper page
  141. Theriault, 1990, Regional assignment of the human C1-inhibitor gene to 11q11-q13.1, Hum Genet, 84, 477, 10.1007/BF00195824 · doi:10.1007/bf00195824
  142. Janson, 1991, Detailed physical map of human chromosomal region 11q12-13 shows high meiotic recombination rate around the MEN1 locus, Proc Natl Acad Sci U S A, 88, 10609, 10.1073/pnas.88.23.10609 · doi:10.1073/pnas.88.23.10609
  143. Carter, 1991, Complete nucleotide sequence of the gene for human C1 inhibitor with an unusually high density of Alu elements, Eur J Biochem, 197, 301, 10.1111/j.1432-1033.1991.tb15911.x · doi:10.1111/j.1432-1033.1991.tb15911.x
  144. Ariga, 1990, Recombinations between Alu repeat sequences that result in partial deletions within the C1 inhibitor gene, Genomics, 8, 607, 10.1016/0888-7543(90)90246-Q · doi:10.1016/0888-7543(90)90246-q
  145. Stoppa-Lyonnet, 1991, Recombinational biases in the rearranged C1-inhibitor genes of hereditary angioedema patients, Am J Hum Genet, 49, 1055
  146. Bissler, 1994, Contiguous deletion and duplication mutations resulting in type 1 hereditary angioneurotic edema, Hum Genet, 93, 265, 10.1007/BF00212020 · DOI
  147. Skriver, 1989, CpG mutations in the reactive site of human C1 inhibitor, J Biol Chem, 264, 3066, 10.1016/S0021-9258(18)94031-7 · DOI
  148. Tosi, 1998, Molecular genetics of C1 inhibitor, Immunobiology, 199, 358, 10.1016/S0171-2985(98)80040-5 · DOI
  149. Pappalardo, 2000, Frequent de novo mutations and exon deletions in the C1inhibitor gene of patients with angioedema, J Allergy Clin Immunol, 106, 1147, 10.1067/mai.2000.110471 · DOI · Paper page
  150. Eldering, 1995, COOH-terminal substitutions in the serpin C1 inhibitor that cause loop overinsertion and subsequent multimerization, J Biol Chem, 270, 2579, 10.1074/jbc.270.6.2579 · doi:10.1074/jbc.270.6.2579
  151. Kramer, 1993, Transinhibition of C1 inhibitor synthesis in type I hereditary angioneurotic edema, J Clin Invest, 91, 1258, 10.1172/JCI116290 · DOI
  152. Lachmann, 1984, The catabolism of C1(-)-inhibitor and the pathogenesis of hereditary angio-edema, Acta Pathol Microbiol Immunol Scand Suppl, 284, 35
  153. Davis, 1997, C1 inhibitor. Functional analysis of naturally-occurring mutant proteins, Adv Exp Med Biol, 425, 185, 10.1007/978-1-4615-5391-5_18 · doi:10.1007/978-1-4615-5391-5_18
  154. Davis, 1992, C1 inhibitor hinge region mutations produce dysfunction by different mechanisms, Nat Genet, 1, 354, 10.1038/ng0892-354 · DOI
  155. Zahedi, 1995, Unique C1 inhibitor dysfunction in a kindred without angioedema, II: identification of an Ala443–Val substitution and functional analysis of the recombinant mutant protein, J Clin Invest, 95, 1299, 10.1172/JCI117780 · DOI
  156. Aulak, 1993, A hinge region mutation in C1-inhibitor (Ala436–Thr) results in nonsubstrate-like behavior and in polymerization of the molecule, J Biol Chem, 268, 18088, 10.1016/S0021-9258(17)46815-3 · doi:10.1016/s0021-9258(17)46815-3
  157. Bos, 2002, Structural and functional aspects of C1-inhibitor, Immunobiology, 205, 518, 10.1078/0171-2985-00151 · doi:10.1078/0171-2985-00151
  158. Bissler, 1998, C1 inhibitor gene sequence facilitates frameshift mutations, Mol Med, 4, 795, 10.1007/BF03401772 · doi:10.1007/bf03401772
  159. Grompe, 1993, The rapid detection of unknown mutations in nucleic acids, Nat Genet, 5, 111, 10.1038/ng1093-111 · DOI · Paper page
  160. Taylor, 1999, Enzymatic methods for mutation scanning, Genet Anal, 14, 181, 10.1016/S1050-3862(98)00029-1 · DOI
  161. Cotton, 1988, Reactivity of cytosine and thymine in single-base-pair mismatches with hydroxylamine and osmium tetroxide and its application to the study of mutations, Proc Natl Acad Sci U S A, 85, 4397, 10.1073/pnas.85.12.4397 · DOI · Paper page
  162. Ellis, 1998, Chemical cleavage of mismatch: a new look at an established method, Hum Mutat, 11, 345, 10.1002/(SICI)1098-1004(1998)11:5<345::AID-HUMU1>3.0.CO;2-0 · doi:10.1002/(sici)1098-1004(1998)11:5<345::aid-humu1>3.0.co;2-0
  163. Verpy, 1993, C1 inhibitor mutations which affect intracellular transport and secretion in type I hereditary angioedema, Behring Inst Mitt, 120
  164. Cotton, 1993, Current methods of mutation detection, Mutat Res, 285, 125, 10.1016/0027-5107(93)90060-S · doi:10.1016/0027-5107(93)90060-s
  165. Verpy, 1994, Efficient detection of point mutations on color-coded strands of target DNA, Proc Natl Acad Sci U S A, 91, 1873, 10.1073/pnas.91.5.1873 · doi:10.1073/pnas.91.5.1873
  166. Verpy, 1996, Exhaustive mutation scanning by fluorescence-assisted mismatch analysis discloses new genotype-phenotype correlations in angiodema, Am J Hum Genet, 59, 308
  167. Xiao, 2001, Denaturing high-performance liquid chromatography: a review, Hum Mutat, 17, 439, 10.1002/humu.1130 · DOI · Paper page
  168. Fodde, 1994, Mutation detection by denaturing gradient gel electrophoresis (DGGE), Hum Mutat, 3, 83, 10.1002/humu.1380030202 · DOI
  169. Freiberger, 2002, Five novel mutations in the C1 inhibitor gene (C1NH) leading to a premature stop codon in patients with type I hereditary angioedema, Hum Mutat, 19, 461, 10.1002/humu.9029 · doi:10.1002/humu.9029
  170. Nataraj, 1999, Single-strand conformation polymorphism and heteroduplex analysis for gel-based mutation detection, Electrophoresis, 20, 1177, 10.1002/(SICI)1522-2683(19990101)20:6<1177::AID-ELPS1177>3.0.CO;2-2 · DOI · Paper page
  171. Bissler, 1997, Molecular defects in hereditary angioneurotic edema, Proc Assoc Am Physicians, 109, 164
  172. Blanch, 2002, Detection of C1 inhibitor (SERPING1/C1NH) mutations in exon 8 in patients with hereditary angioedema: evidence for 10 novel mutations, Hum Mutat, 20, 405, 10.1002/humu.9073 · DOI
  173. Cicardi, 1987, Molecular basis for the deficiency of complement 1 inhibitor in type I hereditary angioneurotic edema, J Clin Invest, 79, 698, 10.1172/JCI112873 · DOI
  174. Stoppa-Lyonnet, 1987, Altered C1 inhibitor genes in type I hereditary angioedema, N Engl J Med, 317, 1, 10.1056/NEJM198707023170101 · DOI
  175. McPhaden, 1991, Restriction fragment length polymorphism analysis of the C1-inhibitor gene in hereditary C1-inhibitor deficiency, Clin Genet, 39, 161, 10.1111/j.1399-0004.1991.tb03006.x · doi:10.1111/j.1399-0004.1991.tb03006.x
  176. Duponchel, 2001, Rapid detection by fluorescent multiplex PCR of exon deletions and duplications in the C1 inhibitor gene of hereditary angioedema patients, Hum Mutat, 17, 61, 10.1002/1098-1004(2001)17:1<61::AID-HUMU7>3.0.CO;2-9 · doi:10.1002/1098-1004(2001)17:1<61::aid-humu7>3.0.co;2-9
  177. Cumming, 2003, The effect of sequence variations within the coding region of the C1 inhibitor gene on disease expression and protein function in families with hereditary angio-oedema, J Med Genet, 40, e114, 10.1136/jmg.40.10.e114 · doi:10.1136/jmg.40.10.e114
  178. Zahedi, 1999, The promoter of the C1 inhibitor gene contains a polypurine-polypyrimidine segment that enhances transcriptional activity, J Immunol, 162, 7249, 10.4049/jimmunol.162.12.7249 · doi:10.4049/jimmunol.162.12.7249
  179. Kalmar, 2003, Mutation screening of the C1 inhibitor gene among Hungarian patients with hereditary angioedema, Hum Mutat, 22, 498, 10.1002/humu.9202 · DOI
  180. Sugiyama, 2001, Hereditary angioedema with a de novo mutation of exon 8 in the C1 inhibitor gene showing recurrent edema of the hands around the peripheral joints: importance for the differential diagnosis of joint swelling, Arthritis Rheum, 44, 974, 10.1002/1529-0131(200104)44:4<974::AID-ANR155>3.0.CO;2-1 · doi:10.1002/1529-0131(200104)44:4<974::aid-anr155>3.0.co;2-1
  181. Ariga, 1989, Type I C1 inhibitor deficiency with a small messenger RNA resulting from deletion of one exon, J Clin Invest, 83, 1888, 10.1172/JCI114095 · DOI
  182. Kramer, 1991, Synthesis of C1 inhibitor in fibroblasts from patients with type I and type II hereditary angioneurotic edema, J Clin Invest, 87, 1614, 10.1172/JCI115175 · DOI
  183. Ernst, 1996, Impaired production of both normal and mutant C1 inhibitor proteins in type I hereditary angioedema with a duplication in exon 8, J Immunol, 157, 405, 10.4049/jimmunol.157.1.405 · DOI
  184. Eldering, 1988, Expression of functional human C1 inhibitor in COS cells, J Biol Chem, 263, 11776, 10.1016/S0021-9258(18)37851-7 · doi:10.1016/s0021-9258(18)37851-7
  185. Eldering, 1992, Characterization of recombinant C1 inhibitor P1 variants, J Biol Chem, 267, 7013, 10.1016/S0021-9258(19)50529-4 · doi:10.1016/s0021-9258(19)50529-4
  186. Zahedi, 1996, Characterization of C1 inhibitor-Ta: a dysfunctional C1INH with deletion of lysine 251, J Biol Chem, 271, 24307, 10.1074/jbc.271.39.24307 · DOI
  187. Zahedi, 2001, C1 inhibitor: analysis of the role of amino acid residues within the reactive center loop in target protease recognition, J Immunol, 167, 1500, 10.4049/jimmunol.167.3.1500 · DOI
  188. Hunt, 1980, A surprising new protein superfamily containing ovalbumin, antithrombin-III, and alpha 1-proteinase inhibitor, Biochem Biophys Res Commun, 95, 864, 10.1016/0006-291X(80)90867-0 · DOI · Paper page
  189. Salvesen, 1985, Primary structure of the reactive site of human C1-inhibitor, J Biol Chem, 260, 2432, 10.1016/S0021-9258(18)89572-2 · doi:10.1016/s0021-9258(18)89572-2
  190. Tosi, 1986, Molecular cloning of human C1 inhibitor: sequence homologies with alpha 1-antitrypsin and other members of the serpins superfamily, Gene, 42, 265, 10.1016/0378-1119(86)90230-1 · doi:10.1016/0378-1119(86)90230-1
  191. Silverman, 2001, The serpins are an expanding superfamily of structurally similar but functionally diverse proteins: evolution, mechanism of inhibition, novel functions, and a revised nomenclature, J Biol Chem, 276, 33293, 10.1074/jbc.R100016200 · DOI · Paper page
  192. Caliezi, 2000, C1-Esterase inhibitor: an anti-inflammatory agent and its potential use in the treatment of diseases other than hereditary angioedema, Pharmacol Rev, 52, 91, 10.1016/S0031-6997(24)01437-6 · DOI · Paper page
  193. Cugno, 2001, In vitro interaction of C1-inhibitor with thrombin, Blood Coagul Fibrinolysis, 12, 253, 10.1097/00001721-200106000-00005 · doi:10.1097/00001721-200106000-00005
  194. Harpel, 1970, C1 inactivator inhibition by plasmin, J Clin Invest, 49, 568, 10.1172/JCI106267 · doi:10.1172/jci106267
  195. Booth, 1987, Plasminogen activator in normal subjects after exercise and venous occlusion: t-PA circulates as complexes with C1-inhibitor and PAI-1, Blood, 69, 1600, 10.1182/blood.V69.6.1600.1600 · DOI
  196. Wuillemin, 1997, Potentiation of C1 inhibitor by glycosaminoglycans: dextran sulfate species are effective inhibitors of in vitro complement activation in plasma, J Immunol, 159, 1953, 10.4049/jimmunol.159.4.1953 · doi:10.4049/jimmunol.159.4.1953
  197. Wuillemin, 1996, Modulation of contact system proteases by glycosaminoglycans: selective enhancement of the inhibition of factor XIa, J Biol Chem, 271, 12913, 10.1074/jbc.271.22.12913 · doi:10.1074/jbc.271.22.12913
  198. Bos, 2001, The potentiation of human C1-inhibitor by dextran sulphate is transient in vivo: studies in a rat model, Int Immunopharmacol, 1, 1583, 10.1016/S1567-5769(01)00073-X · doi:10.1016/s1567-5769(01)00073-x
  199. Bock, 1986, Human C1 inhibitor: primary structure, cDNA cloning, and chromosomal localization, Biochemistry, 25, 4292, 10.1021/bi00363a018 · DOI · Paper page
  200. Bos, 2003, The functional integrity of the serpin domain of C1-inhibitor depends on the unique N-terminal domain, as revealed by a pathological mutant, J Biol Chem, 278, 29463, 10.1074/jbc.M302977200 · doi:10.1074/jbc.m302977200

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Metadata

Authors
Agostoni, A., Aygören-Pürsün, E., Binkley, K. E., Blanch, A., Bork, K., Bouillet, L., Bucher, C., Castaldo, A. J., Cicardi, M., Davis, A. E., De Carolis, C., Drouet, C., Duponchel, C., Farkas, H., Fáy, K., Fekete, B., Fischer, B., Fontana, L., Füst, G., Giacomelli, R., Gröner, A., Erik Hack, C., Harmat, G., Jakenfelds, J., Juers, M., Kalmár, L., Kaposi, P. N., Karádi, I., Kitzinger, A., Kollár, T., Kreuz, W., Lakatos, P., Longhurst, H. J., Lopez-Trascasa, M., Martinez-Saguer, I., Monnier, N., Nagy, I., Németh, É., Nielsen, E. W., Nuijens, J. H., O'Grady, C., Pappalardo, E., Penna, V., Perricone, C., Perricone, R., Rauch, U., Roche, O., Rusicke, E., Späth, P. J., Szendei, G., Takács, E., Tordai, A., Truedsson, L., Varga, L., Visy, B., Williams, K., Zanichelli, A., & Zingale, L.
Venue
Journal of Allergy and Clinical Immunology
Publisher
Elsevier BV
Published
2004-09
Volume
114
Issue
3
Pages
S51-S131
ISSN
0091-6749 (ISSN-L)
DOI
10.1016/j.jaci.2004.06.047
OpenAlex
W2081368903
Cited by
646
References
10
FWCI
11.36
Type
journal article
Language
en
Open access
bronze
Licence
  • www.elsevier.com/tdm/userlicense/1.0/ (tdm)
  • www.elsevier.com/legal/tdmrep-license (tdm)

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CoChat. (2026). Citation check: Hereditary and acquired angioedema: Problems and progress: Proceedings of the third C1 esterase inhibitor deficiency workshop and beyond. https://app.cochat.ai/papers/10.1016/j.jaci.2004.06.047
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Agostoni, A., Aygören-Pürsün, E., Binkley, K. E., Blanch, A., Bork, K., Bouillet, L., Bucher, C., Castaldo, A. J., Cicardi, M., Davis, A. E., De Carolis, C., Drouet, C., Duponchel, C., Farkas, H., Fáy, K., Fekete, B., Fischer, B., Fontana, L., Füst, G., . . . Zingale, L. (2004). Hereditary and acquired angioedema: Problems and progress: Proceedings of the third C1 esterase inhibitor deficiency workshop and beyond. Journal of Allergy and Clinical Immunology. https://doi.org/10.1016/j.jaci.2004.06.047

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