Assessment and management of statin-associated muscle symptoms (SAMS): A clinical perspective from the National Lipid Association
Open accessAbstract
Statin-associated muscle symptoms (SAMS) are the most common form of statin intolerance and are associated with increased risk of cardiovascular events that manifest from statin underutilization and discontinuation. The reported frequencies of SAMS are divergent in the literature. The writing group estimates the prevalence of SAMS, namely all muscle symptoms temporally related to statin use but without regard to causality, to be about 10% (range 5% to 25%), and the prevalence of pharmacological SAMS, specifically muscle symptoms resulting from pharmacological properties of the statin, to be about 1-2% (range 0.5% to 4%). In clinical practice, SAMS are likely to result from a combination of pharmacological and nonpharmacological effects, however this does not make the symptoms any less clinically relevant. Regardless of the etiology, SAMS need to be addressed in accordance with patients' preferences and experiences. This clinical perspective reviews the epidemiology and underlying pathophysiology of SAMS, and the cardiovascular consequences resulting from statin discontinuation. We present patient-centered clinical and communication strategies to mitigate SAMS and improve medication adherence and outcomes among statin users. Treatment strategies include 1) optimizing lifestyle interventions, 2) modulating risk factors that may contribute to muscle symptoms, 3) optimizing statin tolerability by dose reduction, decreased dosing frequency, or use of an alternate statin with more favorable pharmacokinetic properties, and 4) use of non-statins, emphasizing those with evidence for atherosclerotic risk reduction, either in combination with or in place of statin therapy depending on the patient's circumstances. The focus of this clinical perspective is sustainable lipoprotein goal achievement, which is important for cardiovascular risk reduction.
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Recent narrative reviews on the management of SAMS found that further research is needed to close the knowledge gap.
“Recent narrative reviews on the management of SAMS found that further research is needed to close the knowledge gap [19].”
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Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease
Sabatine, M. S., Giugliano, R. P., Keech, A. C., Honarpour, N., Wiviott, S. D., Murphy, S. A., Kuder, J. F., Wang, H., Liu, T., Wasserman, S. M., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1615664 · Cited by 6,138 · see citing works
Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
Cannon, C. P., Blazing, M. A., Giugliano, R. P., McCagg, A., White, J. A., Theroux, P., Darius, H., Lewis, B. S., Ophuis, T. O., Jukema, J. W., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1410489 · Cited by 4,487 · see citing works
Ference, B. A., Ginsberg, H. N., Graham, I., Ray, K. K., Packard, C. J., Bruckert, E., Hegele, R. A., Krauss, R. M., Raal, F. J., Schunkert, H., et al. (2017) · European Heart Journal · doi:10.1093/eurheartj/ehx144 · Cited by 3,962 · see citing works
Helsinki Heart Study: Primary-Prevention Trial with Gemfibrozil in Middle-Aged Men with Dyslipidemia
Frick, M. H., Elo, O., Haapa, K., Heinonen, O. P., Heinsalmi, P., Helo, P., Huttunen, J. K., Kaitaniemi, P., Koskinen, P., Manninen, V., et al. (1987) · New England Journal of Medicine · doi:10.1056/nejm198711123172001 · Cited by 3,881 · see citing works
Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome
Schwartz, G. G., Steg, P. G., Szarek, M., Bhatt, D. L., Bittner, V. A., Diaz, R., Edelberg, J. M., Goodman, S. G., Hanotin, C., Harrington, R. A., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1801174 · Cited by 3,634 · see citing works
Rubins, H. B., Robins, S. J., Collins, D., Fye, C. L., Anderson, J. W., Elam, M. B., Faas, F. H., Linares, E., Schaefer, E. J., Schectman, G., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908053410604 · Cited by 3,439 · see citing works
Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy
The AIM-HIGH Investigators (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1107579 · Cited by 2,911 · see citing works
Grundy, S. M., Stone, N. J., Bailey, A. L., Beam, C., Birtcher, K. K., Blumenthal, R. S., Braun, L. T., de Ferranti, S., Faiella-Tommasino, J., Forman, D. E., et al. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.11.003 · Cited by 2,691 · see citing works
<i>SLCO1B1</i> Variants and Statin-Induced Myopathy — A Genomewide Study
(2008) · New England Journal of Medicine · doi:10.1056/nejmoa0801936 · Cited by 2,043 · see citing works
Interpretation of the evidence for the efficacy and safety of statin therapy
Collins, R., Reith, C., Emberson, J., Armitage, J., Baigent, C., Blackwell, L., Blumenthal, R., Danesh, J., Smith, G. D., DeMets, D., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31357-5 · Cited by 1,857 · see citing works
Clofibrate and Niacin in Coronary Heart Disease
Stamler, J. (1975) · JAMA · doi:10.1001/jama.1975.03240160024021 · Cited by 1,750 · see citing works
Effects of extended-release niacin with laropiprant in high-risk patients
The HPS2-THRIVE Collaborative Group (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1300955 · Cited by 1,668 · cited 1× · see citing works
“82 , 83 The LDL-C-lowering efficacy is modest, but cholestyramine monotherapy is also proven to reduce the risk of cardiovascular events.”
Stroes, E. S., Thompson, P. D., Corsini, A., Vladutiu, G. D., Raal, F. J., Ray, K. K., Roden, M., Stein, E., Tokgözoğlu, L., Nordestgaard, B. G., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv043 · Cited by 1,443 · see citing works
Self-citationDepression and cardiovascular disease: a clinical review
Hare, D. L., Toukhsati, S. R., Johansson, P., & Jaarsma, T. (2014) · European Heart Journal · doi:10.1093/eurheartj/eht462 · Cited by 1,362 · see citing works
Bruckert, E., Hayem, G., Dejager, S., Yau, C., & Bégaud, B. (2005) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-005-5686-z · Cited by 1,226 · see citing works
Ward, N. C., Watts, G. F., & Eckel, R. H. (2019) · Circulation Research · doi:10.1161/circresaha.118.312782 · Cited by 772 · see citing works
Newman, C. B., Preiss, D., Tobert, J. A., Jacobson, T. A., Page, R. L., II, Goldstein, L. B., Chin, C. C., Tannock, L. R., Miller, M. J., Raghuveer, G., et al. (2019) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atv.0000000000000073 · Cited by 761 · see citing works
Self-citationStatin-Associated Side Effects
Thompson, P. D., Panza, G. A., Zaleski, A. L., & Taylor, B. A. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.02.071 · Cited by 756 · see citing works
Lloyd-Jones, D. M., Morris, P. B., Ballantyne, C. M., Birtcher, K. K., Covington, A. M., DePalma, S. M., Minissian, M. B., Orringer, C. E., Smith, S. C., Waring, A. A., et al. (2022) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2022.07.006 · Cited by 569 · see citing works
Rumsfeld, J. S., Alexander, K. P., Goff, D. C., Graham, M. M., Ho, P. M., Masoudi, F. A., Moser, D. K., Roger, V. L., Slaughter, M. S., Smolderen, K. G., et al. (2013) · Circulation · doi:10.1161/cir.0b013e3182949a2e · Cited by 540 · see citing works
Nissen, S. E., Stroes, E., Dent-Acosta, R. E., Rosenson, R. S., Lehman, S. J., Sattar, N., Preiss, D., Bruckert, E., Ceška, R., Lepor, N., et al. (2016) · JAMA · doi:10.1001/jama.2016.3608 · Cited by 522 · see citing works
Effect of statins on skeletal muscle function
Parker, B. A., Capizzi, J. A., Grimaldi, A. S., Clarkson, P. M., Cole, S. M., Keadle, J., Chipkin, S., Pescatello, L. S., Simpson, K., White, C. M., et al. (2013) · Circulation · doi:10.1161/circulationaha.112.136101 · Cited by 500 · see citing works
Cohen, J. D., Brinton, E. A., Ito, M. K., & Jacobson, T. A. (2012) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2012.03.003 · Cited by 486 · see citing works
Self-citationAn assessment by the statin muscle safety task force: 2014 update
Rosenson, R. S., Baker, S. K., Jacobson, T. A., Kopecky, S. L., & Parker, B. A. (2014) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2014.03.004 · Cited by 485 · see citing works
Self-citationMoriarty, P. M., Thompson, P. D., Cannon, C. P., Guyton, J. R., Bergeron, J., Zieve, F. J., Bruckert, E., Jacobson, T. A., Kopecky, S. L., Baccara-Dinet, M. T., et al. (2015) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2015.08.006 · Cited by 470 · see citing works
Self-citationSafety and efficacy of statin therapy
Adhyaru, B. B., & Jacobson, T. A. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0098-5 · Cited by 424 · see citing works
Self-citationBanach, M., Rizzo, M., Toth, P. P., Farnier, M., Davidson, M. H., Al‐Rasadi, K., Aronow, W. S., Athyros, V. G., Djuric, D. M., Владиславович, Е. М., et al. (2015) · Archives of Medical Science · doi:10.5114/aoms.2015.49807 · Cited by 381 · see citing works
Cooper‐DeHoff, R. M., Niemi, M., Ramsey, L. B., Luzum, J. A., Tarkiainen, E. K., Straka, R. J., Gong, L., Tuteja, S., Wilke, R. A., Wadelius, M., et al. (2022) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.2557 · Cited by 366 · see citing works
Anker, S. D., Agewall, S., Borggrefe, M., Calvert, M., Jaime Caro, J., Cowie, M. R., Ford, I., Paty, J. A., Riley, J. P., Swedberg, K., et al. (2014) · European Heart Journal · doi:10.1093/eurheartj/ehu205 · Cited by 362 · see citing works
Wiggins, B. S., Saseen, J. J., Page, R. L., II, Reed, B. N., Sneed, K., Kostis, J. B., Lanfear, D. E., Virani, S. S., & Morris, P. B. (2016) · Circulation · doi:10.1161/cir.0000000000000456 · Cited by 339 · see citing works
Nielsen, S. F., & Nordestgaard, B. G. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv641 · Cited by 329 · see citing works
Kim, B., Hong, S., Lee, Y., Hong, S. J., Yun, K. H., Hong, B., Heo, J. H., Rha, S., Cho, Y., Lee, S., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(22)00916-3 · Cited by 329 · see citing works
Impact of statin adherence on cardiovascular disease and mortality outcomes: a systematic review
De Vera, M. A., Bhole, V., Burns, L. C., & Lacaille, D. (2014) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.12339 · Cited by 289 · see citing works
Reith, C. A., Baigent, C., Blackwell, L. S., Emberson, J., Spata, E., Davies, K., Halls, H. J., Holland, L., Wilson, K., Armitage, J., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(22)01545-8 · Cited by 288 · see citing works
Diagnosis and Treatment of Heterozygous Familial Hypercholesterolemia
McGowan, M. P., Dehkordi, S. H. H., Moriarty, P. M., & Duell, P. B. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.119.013225 · Cited by 273 · see citing works
Self-citationMancini, G. B. J., Baker, S. K., Bergeron, J., FITCHETT, D. H., Frohlich, J. J., Genest, J. J., Gupta, M., Hegele, R. A., Ng, D. S., Pearson, G. J., et al. (2016) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2016.01.003 · Cited by 253 · see citing works
Turner, R. M., & Pirmohamed, M. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm9010022 · Cited by 201 · see citing works
A randomized trial of Coenzyme Q10 in patients with confirmed statin myopathy
Taylor, B. A., Lorson, L., White, C. M., & Thompson, P. D. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.12.016 · Cited by 200 · see citing works
Side Effect Patterns in a Crossover Trial of Statin, Placebo, and No Treatment
Howard, J. P., Wood, F. A., Finegold, J. A., Nowbar, A. N., Thompson, D. M., Arnold, A. D., Rajkumar, C. A., Connolly, S., Cegla, J., Stride, C., et al. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.07.022 · Cited by 198 · see citing works
Cheeley, M. K., Saseen, J. J., Agarwala, A., Ravilla, S., Ciffone, N., Jacobson, T. A., Dixon, D. L., & Maki, K. C. (2022) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2022.05.068 · Cited by 197 · see citing works
Self-citationStatin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials
Herrett, E., Williamson, E., Brack, K., Beaumont, D., Perkins, A., Thayne, A., Shakur-Still, H., Roberts, I., Prowse, D., Goldacre, B., et al. (2021) · BMJ · doi:10.1136/bmj.n135 · Cited by 191 · see citing works
An updated review of pharmacokinetic drug interactions and pharmacogenetics of statins
Hirota, T., Fujita, Y., & Ieiri, I. (2020) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2020.1801634 · Cited by 190 · see citing works
Qu, H., Guo, M., Chai, H., Wang, W., Gao, Z., & Shi, D. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.118.009835 · Cited by 178 · cited 1× · see citing works
“72 , 73 One analysis failed to show an increase in statin adherence with CoQ 10 supplementation, which is perhaps a more important outcome measure than pain score improvement.”
Michalska, M., Sahebkar, A., Mikhailidis, D. P., Rysz, J., Muntner, P., Toth, P. P., Jones, S. R., Rizzo, M., Hovingh, G. K., Farnier, M., et al. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.10.118 · Cited by 171 · see citing works
Cardio-Oncology Drug Interactions: A Scientific Statement From the American Heart Association
Beavers, C. J., Rodgers, J. E., Bagnola, A. J., Beckie, T. M., Campia, U., Palo, K. E. D., Okwuosa, T. M., Przespolewski, E. R., & Sj, D. (2022) · Circulation · doi:10.1161/cir.0000000000001056 · Cited by 168 · see citing works
Giral, P., Neumann, A., Weill, A., & Coste, J. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehz458 · Cited by 167 · see citing works
An assessment by the Statin Intolerance Panel: 2014 update
Guyton, J. R., Bays, H. E., Grundy, S. M., & Jacobson, T. A. (2014) · Journal of clinical lipidology · doi:10.1016/j.jacl.2014.03.002 · Cited by 165 · see citing works
Self-citationA clinician's guide to statin drug-drug interactions
Kellick, K. A., Bottorff, M. B., & Toth, P. P. (2014) · Journal of clinical lipidology · doi:10.1016/j.jacl.2014.02.010 · Cited by 162 · see citing works
Fibrates and statins in the treatment of hyperlipidaemia: an appraisal of their efficacy and safety
Shepherd, J. (1995) · European Heart Journal · doi:10.1093/eurheartj/16.1.5 · Cited by 158 · see citing works
Distribution of creatine kinase in the general population: Implications for statin therapy
Brewster, L. M., Mairuhu, G., Sturk, A., & van Montfrans, G. A. (2007) · American Heart Journal · doi:10.1016/j.ahj.2007.06.008 · Cited by 148 · see citing works
Rosenson, R. S., Miller, K., Bayliss, M. S., Sanchez, R. J., Baccara‐Dinet, M. T., Chibedi-De-Roche, D., Taylor, B. A., Khan, I., Manvelian, G. Z., White, M. K., et al. (2017) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-017-6723-4 · Cited by 142 · see citing works
Self-citationPenson, P. E., Mancini, G. B. J., Toth, P. P., Martin, S. S., Watts, G. F., Sahebkar, A., Mikhailidis, D. P., Banach, M., & on behalf of Lipid and Blood Pressure Meta‐Analysis Collaboration (LBPMC) Group & International Lipid Expert Panel (ILEP) (2018) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12344 · Cited by 110 · see citing works
Statin Discontinuation and Cardiovascular Events Among Older People in Denmark
Thompson, W., Morin, L., Jarbøl, D. E., Andersen, J. H., Ernst, M. T., Nielsen, J. B., Haastrup, P., Schmidt, M., & Pottegård, A. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.36802 · Cited by 101 · see citing works
Shared decision‐making for older adults with cardiovascular disease
Backman, W., Levine, S. A., WENGER, N. K., & Harold, J. G. (2019) · Clinical Cardiology · doi:10.1002/clc.23267 · Cited by 95 · see citing works
Continued Statin Prescriptions After Adverse Reactions and Patient Outcomes
Zhang, H., Plutzky, J., Shubina, M., & Turchin, A. (2017) · Annals of Internal Medicine · doi:10.7326/m16-0838 · Cited by 93 · see citing works
Statin-associated muscle symptoms—Managing the highly intolerant
Backes, J. M., Ruisinger, J. F., Gibson, C., & Moriarty, P. M. (2017) · Journal of clinical lipidology · doi:10.1016/j.jacl.2017.01.006 · Cited by 88 · see citing works
Statin-Associated Muscle Disease: Advances in Diagnosis and Management
Taylor, B. A., & Thompson, P. D. (2018) · Neurotherapeutics · doi:10.1007/s13311-018-0670-z · Cited by 85 · see citing works
Creatine kinase in the U.S. population
George, M., McGill, N., & Baker, J. F. (2016) · Medicine · doi:10.1097/md.0000000000004344 · Cited by 75 · see citing works
Brunham, L. R., Baker, S. K., Mammen, A. L., Mancini, G. B. J., & Rosenson, R. S. (2018) · Cardiovascular Research · doi:10.1093/cvr/cvy119 · Cited by 71 · see citing works
Coenzyme Q10 for Patients With Cardiovascular Disease
Raizner, A. E., & Quiñones, M. A. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.12.009 · Cited by 66 · see citing works
Jacobson, T. A., Cheeley, M. K., Jones, P. H., Forge, R. L., Maki, K. C., López, J. A. G., Xiang, P., Bushnell, D. M., Martin, M. L., & Cohen, J. D. (2019) · Journal of clinical lipidology · doi:10.1016/j.jacl.2019.04.011 · Cited by 57 · see citing works
Self-citationKennedy, C., Köller, Y., & Surkova, E. (2020) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2020.03.006 · Cited by 51 · see citing works
Yetman, H. E., Cox, N., Adler, S. R., Hall, K. T., & Stone, V. E. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.788230 · Cited by 50 · see citing works
Nocebo/drucebo effect in statin-intolerant patients: an attempt at recommendations
Penson, P. E., & Banach, M. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab358 · Cited by 47 · see citing works
Scott, R. S., Lintott, C. J., & Wilson, M. J. (1991) · PubMed · Cited by 43 · see citing works
Jones, L. K., Tilberry, S., Gregor, C. M., Yaeger, L., Hu, Y., Sturm, A. C., Seaton, T., Waltz, T. J., Rahm, A. K., Goldberg, A. C., et al. (2021) · Implementation Science · doi:10.1186/s13012-021-01108-0 · Cited by 40 · see citing works
Self-citationStatin-associated muscle symptoms: position paper from the Luso-Latin American Consortium
Sposito, A. C., Faria‐Neto, J. R., de Carvalho, L. S. F., Lorenzatti, A. J., Cafferata, A., Elikir, G. D., Esteban, E., Villegas, E. C. M., Bodanese, L. C., Rodrigo Alonso, K., et al. (2016) · Current Medical Research and Opinion · doi:10.1080/03007995.2016.1252740 · Cited by 38 · see citing works
Taylor, B. A., Sanchez, R. J., Jacobson, T. A., Chibedi-De-Roche, D., Manvelian, G. Z., Baccara‐Dinet, M. T., Khan, I., & Rosenson, R. S. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.07.767 · Cited by 29 · see citing works
Self-citationRiegel, B. J., & Dickson, V. V. (2016) · Heart & Lung · doi:10.1016/j.hrtlng.2016.08.003 · Cited by 28 · see citing works
Statin Denial: An Internet-Driven Cult With Deadly Consequences
Nissen, S. E. (2018) · Annals of Internal Medicine · doi:10.7326/l17-0626 · Cited by 27 · see citing works
Taylor, B. A. (2017) · American Journal of Cardiovascular Drugs · doi:10.1007/s40256-017-0251-2 · Cited by 22 · see citing works
Duell, P. B., & Connor, W. E. (2008) · Circulation · doi:10.1161/circ.118.suppl_18.s_470 · Cited by 22 · see citing works
Self-citationOkunrintemi, V., Elizondo, J. V., Stone, N. J., Blankstein, R., Blaha, M. J., Gulati, M., Virani, S. S., Zoghbi, W. A., Michos, E. D., & Nasir, K. (2021) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2021.100281 · Cited by 19 · see citing works
Vitamin D Supplementation to Treat Statin-Associated Muscle Symptoms: A Review
Lowe, K., Kubra, K. T., He, Z. Y., & Carey, K. (2019) · The Senior Care Pharmacist · doi:10.4140/tcp.n.2019.253 · Cited by 14 · see citing works
Tudor, K., Brooks, J., Howick, J., Fox, R., & Aveyard, P. (2022) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.120.007793 · Cited by 9 · see citing works
The value of a specialist lipid clinic
Martin, S. C., & Viljoen, A. (2008) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2007.01667.x · Cited by 9 · see citing works
Influence of Baseline Psychological Health on Muscle Pain During Atorvastatin Treatment
Zaleski, A. L., Taylor, B. A., Pescatello, L. S., Dornelas, E. A., White, C. M., & Thompson, P. D. (2016) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0000000000000382 · Cited by 5 · see citing works
Management strategies in patients with statin-associated muscle symptoms: What is the best strategy?
JOY, T. R., & Brennan, E. T. (2016) · Journal of clinical lipidology · doi:10.1016/j.jacl.2016.06.008 · Cited by 4 · see citing works
Low-Density Lipoprotein (LDL) Apheresis
Duell, P. B. (2015) · Contemporary Endocrinology · doi:10.1007/978-1-60761-424-1_29 · Cited by 3 · see citing works
Self-citationThe clinical lipid specialist. Task Force on Cholesterol Issues, American Heart Association.
LaRosa, J. C. (1990) · Circulation · doi:10.1161/01.cir.82.4.1548 · Cited by 1 · see citing works
Ross, J. L. (2020) · Contemporary cardiology · doi:10.1007/978-3-030-56514-5_34 · Cited by 1 · see citing works
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Self-citationVirani, S. S., Newby, L. K., Arnold, S. V., Bittner, V., Brewer, L. C., Demeter, S. H., Dixon, D. L., Fearon, W. F., Hess, B., Johnson, H. M., et al. (2023) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.04.003 · Cited by 596 · see citing works
Self-citation2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia
Blumenthal, R. S., Morris, P. B., Gaudino, M., Johnson, H. M., Anderson, T. S., Bittner, V. A., Blankstein, R., Brewer, L. C., Cho, L., de Ferranti, S. D., et al. (2026) · JACC · doi:10.1016/j.jacc.2025.11.016 · Cited by 304 · see citing works
Writing Committee Members, Blumenthal, R. S., Morris, P. B., Gaudino, M., Johnson, H. M., Anderson, T. S., Bittner, V. A., Blankstein, R., Brewer, L. C., Cho, L., et al. (2026) · Circulation · doi:10.1161/cir.0000000000001423 · Cited by 122 · see citing works
Self-citationAdvances in statin adverse reactions and the potential mechanisms: A systematic review
Zeng, W., Deng, H., Luo, Y., Zhong, S., Huang, M., & Tomlinson, B. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.12.020 · Cited by 53 · see citing works
First clinical experiences with inclisiran in a real-world setting
Mulder, J. W. C. M., Galema-Boers, A. M. H., & Roeters van Lennep, J. E. (2023) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2023.09.005 · Cited by 49 · see citing works
Cicero, A. F. G., Fogacci, F., Stoian, A. P., & Toth, P. P. (2023) · Nutrients · doi:10.3390/nu15102288 · Cited by 47 · see citing works
Safety of bempedoic acid in patients at high cardiovascular risk and with statin intolerance
Bays, H. E., Bloedon, L. T., Lin, G., Powell, H. A., Louie, M. J., Nicholls, S. J., Lincoff, A. M., & Nissen, S. E. (2023) · Journal of clinical lipidology · doi:10.1016/j.jacl.2023.10.011 · Cited by 38 · see citing works
Ahmad, Z., Agarwala, A., Cuchel, M., Duell, P. B., Hegele, R. A., Hudgins, L. C., Jamison, A., Kalra, D. K., Khera, A., Knowles, J. W., et al. (2026) · Journal of clinical lipidology · doi:10.1016/j.jacl.2026.01.011 · Cited by 35 · see citing works
Self-citationStatin associated muscle symptoms: An update and review
Dicken, W., Mehta, A., Karagiannis, A. D., Jain, V., Vavuranakis, M., Sperling, L. S., & Cassimatis, D. C. (2022) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2022.11.010 · Cited by 30 · see citing works
Lipid-Lowering Nutraceuticals for an Integrative Approach to Dyslipidemia
Cheung, B., Sikand, G., Dineen, E. H., Malik, S., & El-Farra, A. B. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12103414 · Cited by 25 · see citing works
Statin associated muscle symptoms (SAMS): strategies for prevention, assessment and management
Iatan, I., Mancini, G. B. J., Yeoh, E., & Hegele, R. A. (2023) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2023.2215982 · Cited by 24 · see citing works
Shah, M., Shrestha, K., Tseng, C., Goyal, A., Liewluck, T., & Gupta, L. (2024) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.15337 · Cited by 23 · see citing works
Statins and non-alcoholic fatty liver disease: A concise review
Pereira, E. N. G. D. S., Franco, R. L. C., dos Santos, R. D. C., & Daliry, A. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117805 · Cited by 21 · see citing works
The Role of the Clinical Psychologist in the Care of Adults With Cardiovascular Disease
Smolderen, K. G. E., Gillaspy, S. R., Evers, A. W. M., Kovacs, A. H., Massa-Carroll, I., Moons, P., & Mena‐Hurtado, C. (2024) · JACC Advances · doi:10.1016/j.jacadv.2024.100910 · Cited by 23 · see citing works
Self-citationLearnings from Implementation Strategies to Improve Lipid Management
Lan, N. S. R., Chen, R. T., Dwivedi, G., Watts, G. F., Nicholls, S. J., & Nelson, A. J. (2025) · Current Cardiology Reports · doi:10.1007/s11886-024-02174-8 · Cited by 20 · see citing works
Beavers, C. J., Pau, A. K., Glidden, D. V., Hyle, E. P., Kuriakose, S., Martin, S. S., McComsey, G. A., Thompson, M., Virani, S. S., & Baker, J. V. (2025) · Annals of Internal Medicine · doi:10.7326/annals-24-03564 · Cited by 20 · see citing works
The Role of Mitochondria in Statin-Induced Myopathy
Bell, G. M., Thoma, A., Hargreaves, I. P., & Lightfoot, A. P. (2024) · Drug Safety · doi:10.1007/s40264-024-01413-9 · Cited by 21 · see citing works
Bittner, V., Linnebur, S. A., Dixon, D. L., Forman, D. E., Green, A. R., Jacobson, T. A., Orkaby, A. R., Saseen, J. J., & Virani, S. S. (2025) · Journal of clinical lipidology · doi:10.1016/j.jacl.2024.09.005 · Cited by 20 · see citing works
Self-citationPatel, S. B., Belalcazar, L. M., Afreen, S., Balderas, R., Hegele, R. A., Karpe, F., Ponte-Negretti, C. I., & Rajpal, A. (2025) · Endocrine Practice · doi:10.1016/j.eprac.2025.07.014 · Cited by 19 · see citing works
Key genes and processes affected by atorvastatin treatment in mouse diaphragm muscle
Zakyrjanova, G. F., Matigorova, V. A., Kuznetsova, E. A., Анатольевна, Д. С., Tyapkina, O. V., Tsentsevitsky, A. N., Andreyanova, S. N., Odnoshivkina, J. G., Shigapova, R. R., Mukhamedshina, Y. O., et al. (2025) · Archives of Toxicology · doi:10.1007/s00204-025-04056-6 · Cited by 15 · see citing works
Statin Intolerance: an Overview of US and International Guidance
Cheeley, M. K., Clegg, K., Lockridge, C., Schubert, T. J., & Jones, L. K. (2023) · Current Atherosclerosis Reports · doi:10.1007/s11883-023-01124-z · Cited by 15 · see citing works
Self-citationCordero, A., Olmo, R. F., Badimón, L., Santos‐Gallego, C. G., Castellano, J. M., Fácila, L., Rodríguez‐Mañero, M., Bonanad, C., Vilahur, G., Escribano, D., et al. (2023) · Journal of clinical lipidology · doi:10.1016/j.jacl.2023.08.006 · Cited by 16 · see citing works
Bittner, V., Linnebur, S. A., Dixon, D. L., Forman, D. E., Green, A. R., Jacobson, T. A., Orkaby, A. R., Saseen, J. J., & Virani, S. S. (2025) · Journal of the American Geriatrics Society · doi:10.1111/jgs.19398 · Cited by 15 · see citing works
Self-citationStatins Ticagrelor and Rhabdomyolysis: A Coincidence or a Drug Interaction?
Patel, R., Sharma, J. B., & Rajput, S. (2024) · Journal of Lipid and Atherosclerosis · doi:10.12997/jla.2024.13.1.61 · Cited by 12 · see citing works
Jiang, Y., Wang, Y., Ma, S., Qian, L., Jing, Y., Chen, X., & Yang, J. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1415668 · Cited by 16 · see citing works
Fogacci, F., Giovannini, M., Tocci, G., Imbalzano, E., Borghi, C., & Cicero, A. F. G. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13133741 · Cited by 10 · see citing works
Statin-Associated Muscle Symptoms: Identification and Recommendations for Management
Maki, K. C., Kirkpatrick, C. F., Cheeley, M. K., & Jacobson, T. A. (2024) · Current Atherosclerosis Reports · doi:10.1007/s11883-024-01246-y · Cited by 11 · see citing works
Self-citationReasons for non-acceptance of statin therapy by patients at high cardiovascular risk
Xie, M., Martin, S. S., & Turchin, A. (2025) · Scientific Reports · doi:10.1038/s41598-025-01930-2 · Cited by 10 · see citing works
A Critical Appraisal of Lipid Management in the Post-Statin Era
Spitz, J. A., Patel, J., Agarwala, A., Sharma, G. V., Mehta, A., Natarajan, P., Nasir, K., Morris, P. B., Blumenthal, R. S., & Shapiro, M. D. (2025) · JACC Advances · doi:10.1016/j.jacadv.2025.101823 · Cited by 12 · see citing works
Karalis, D. G. (2023) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000896 · Cited by 9 · see citing works
Gougeon, A., Aribi, I., Guernouche, S., Lega, J., Wright, J. M., Verstuyft, C., Lajoinie, A., Gueyffier, F., & Grenet, G. (2024) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2024.118624 · Cited by 9 · see citing works
Stürzebecher, P. E., Katzmann, J. L., Gouni-Berthold, I., Mateev, C., Frenzel, O., Schatz, U., Baessler, A., Köenig, W., Schirmer, S. H., Müller-Kozarez, I., et al. (2025) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2025.100953 · Cited by 7 · see citing works
Safety and Efficacy of Achieving Very Low LDL Cholesterol Concentrations with PCSK9 Inhibitors
Balakrishna, A. M., Kaushik, S., Tandalam, S., Monther, N., Ponamgi, S., Alla, V. M., & Patil, S. M. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14134562 · Cited by 7 · see citing works
Mehta, A., Dixon, D. L., Saeed, A., Kelly, M. S., Gulati, M., Shapiro, M. D., Sperling, L. S., & Virani, S. S. (2023) · Current Cardiology Reports · doi:10.1007/s11886-023-01861-2 · Cited by 7 · see citing works
Self-citationGavilán‐Carrera, B., Soriano‐Maldonado, A., Mediavilla-García, J. D., Lavie, C. J., & Vargas‐Hitos, J. A. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106962 · Cited by 7 · see citing works
Breaking down statin myopathy: understanding the self-limited and autoimmune subtypes
Wright, J., & Christopher‐Stine, L. (2024) · Rheumatology · doi:10.1093/rheumatology/keae284 · Cited by 7 · see citing works
Sun, B., Yew, P. Y., Chi, C., Song, M., Loth, M., Zhang, R., & Straka, R. J. (2023) · JAMIA Open · doi:10.1093/jamiaopen/ooad087 · Cited by 7 · see citing works
Liu, H.-H., Li, S., & Li, J. (2025) · Drugs · doi:10.1007/s40265-025-02167-z · Cited by 7 · see citing works
Alqasrawi, M. N., Al-Mahayri, Z. N., Khasawneh, L. Q., Albawa’neh, A. S., Dabaghie, L., Altoum, S. M., Hamza, D., Aburuz, S., Misra, V., Jamil, G., et al. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1656520 · Cited by 6 · see citing works
Muscle-Related Adverse Events Associated With PCSK9 Inhibitors in a Veteran Population
Cencetti, J. (2023) · Federal Practitioner · doi:10.12788/fp.0357 · Cited by 5 · see citing works
Modern algorithms for statin therapy
Susekov, A. V. (2023) · Russian Journal of Cardiology · doi:10.15829/1560-4071-2023-5594 · Cited by 6 · see citing works
Lipid-lowering approaches to manage statin-intolerant patients
Ruscica, M., Bertoletti, A., Gobbi, C., Sirtori, C. R., Carugo, S., & Corsini, A. (2024) · European Heart Journal Supplements · doi:10.1093/eurheartjsupp/suae007 · Cited by 6 · see citing works
Statin-Intolerant Patients Exhibit Diminished Muscle Strength Regardless of Lipid-Lowering Therapy
Vinci, P., Girolamo, F. G. D., Pellicori, F., Panizon, E., Pirulli, A., Tosoni, L. M., Altamura, N., Rizzo, S., Perin, A., Fiotti, N., et al. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14041221 · Cited by 5 · see citing works
Diagnosis and Management of Statin-Associated Muscle Symptoms
Cha, J., & Hong, S. J. (2025) · Korean Circulation Journal · doi:10.4070/kcj.2025.0285 · Cited by 5 · see citing works
Therapeutic Applications of Natural Products in Biomedicine and Pharmacotherapy
Sah, A. K., Patel, S., Kumar, D. R. P., Mishra, P. S., Mishra, R., Умарович, А. И., Elshaikh, R. H., Agarwal, S., Bhardwaj, A., Choudhary, R. K., et al. (2026) · Life · doi:10.3390/life16060873 · Cited by 4 · see citing works
Clinical Considerations for Healthcare Provider-Administered Lipid-Lowering Medications
Bertolet, B. D., Cabral, K. P., Sullenberger, L. E., McAlister, J., Sandroni, T., & Patel, D. S. (2024) · American Journal of Cardiovascular Drugs · doi:10.1007/s40256-024-00665-1 · Cited by 4 · see citing works
Statin‑associated myasthenia gravis: a real-world retrospective and pharmacovigilance study
Lu, Y., Huang, D., Shen, J., Yang, M., & Wang, S. (2025) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2025.2467183 · Cited by 4 · see citing works
Talasaz, A. H., Cuomo, M., & Maurer, M. S. (2025) · Journal of clinical lipidology · doi:10.1016/j.jacl.2025.08.015 · Cited by 3 · see citing works
Pavanello, C., Cincotto, G., Mombelli, G. G., Castiglione, S., Santolamazza, C., Calabresi, L., Sirtori, C. R., & Albertí, A. (2025) · Journal of clinical lipidology · doi:10.1016/j.jacl.2025.09.033 · Cited by 3 · see citing works
Gergely, T. G., Brenner, G. B., Nagy, R. N., Sayour, N. V., Makkos, A., Kovácsházi, C., Tian, H., Schulz, R., Giricz, Z., Görbe, A., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021585 · Cited by 3 · see citing works
Peyrel, P., Mauriège, P., Frenette, J., Laflamme, N., Greffard, K., Dufresne, S. S., Huth, C., Bergeron, J., & Joanisse, D. R. (2023) · Journal of clinical lipidology · doi:10.1016/j.jacl.2023.12.002 · Cited by 3 · see citing works
Zhao, A., Guo, D., Zhu, M., Gao, A., Li, P., & Fu, A. (2024) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-024-03662-0 · Cited by 3 · see citing works
Familial hypercholesterolaemia and emerging therapeutics
Farias, F. I., Kim, S. M., & Shapiro, M. D. (2023) · Heart · doi:10.1136/heartjnl-2022-321917 · Cited by 3 · see citing works
Grant, J. K., & Orringer, C. E. (2024) · Journal of clinical lipidology · doi:10.1016/j.jacl.2024.07.007 · Cited by 3 · see citing works
Sun, B., Yew, P. Y., Chi, C., Song, M., Loth, M., Liang, Y., Zhang, R., & Straka, R. J. (2024) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.3208 · Cited by 2 · see citing works
The effects of statins on mitochondria – the current state of knowledge
Belczyk, M., Knapik-Czajka, M. E., Gawędzka, A., & Drąg, J. (2025) · Farmacja Polska · doi:10.32383/farmpol/197743 · Cited by 2 · see citing works
Bempedoic Acid: A Review in Cardiovascular Risk Reduction in Statin-Intolerant Patients
McGuigan, A., & Blair, H. A. (2025) · American Journal of Cardiovascular Drugs · doi:10.1007/s40256-024-00714-9 · Cited by 4 · see citing works
Update on statin-associated myopathy symptoms in the view of new clinical management strategies
Musumeci, O., & Drago, S. F. A. (2025) · Current Opinion in Neurology · doi:10.1097/wco.0000000000001405 · Cited by 2 · see citing works
Effects of nonsense genetic variants on OATP1B1 expression and transport activity in vitro
Kiander, W., Rashidpour, H., Gynther, M., Vellonen, K., Neuvonen, M., Vesalainen, L., Huttunen, K. M., Niemi, M., & Kidron, H. (2025) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2025.107322 · Cited by 2 · see citing works
Lee, K., Kang, M., Lee, E. J., Oh, J., Han, N., Lee, J.-Y., Lee, J.-Y., Lee, S. J., Debette, S., Paré, G., et al. (2026) · Journal of Stroke · doi:10.5853/jos.2025.04595 · Cited by 2 · see citing works
Corsetti, G., & Pasini, E. (2026) · Nutrients · doi:10.3390/nu18050722 · Cited by 2 · see citing works
Louro, R., Melo, R. G. E., Ruivo, J., Almeida, A. G., Pinto, F. J., & Caldeira, D. (2023) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2023.2274502 · Cited by 3 · see citing works
Brobst, M., Chapet, N., Benchalkha, D., Bourgeois, E., Herman, F., Molinari, N., Leclercq, F., Pasquié, J., Breuker, C., Sultan, A., et al. (2024) · Archives of cardiovascular diseases · doi:10.1016/j.acvd.2024.10.332 · Cited by 2 · see citing works
The Role of Statins in Managing Chronic Kidney Disease: A Comprehensive Review
Toshniwal, S. S., Parepalli, A., Loya, A., Toshniwal, T., Kumar, S., & Acharya, S. (2025) · International journal of Nutrition Pharmacology Neurological Diseases · doi:10.4103/ijnpnd.ijnpnd_146_24 · Cited by 2 · see citing works
Beyond the Generalized Weakness: A Rare Case of Statin-Induced Immune-Mediated Necrotizing Myopathy
Sakai, L., Kazbour, H., & Huang, J. G. (2025) · Journal of Investigative Medicine High Impact Case Reports · doi:10.1177/23247096251344727 · Cited by 2 · see citing works
The Use of Pharmacogenomics in Cardiovascular Care
Spahn, C., Walker, T. K., Byurat, S., & Palaniappan, L. P. (2025) · Nursing Clinics of North America · doi:10.1016/j.cnur.2024.12.007 · Cited by 1 · see citing works
Qi, G., Rao, A. M., Tariq, S., & Ledesma, L. D. (2025) · Cureus · doi:10.7759/cureus.86246 · Cited by 1 · see citing works
Zeeshan, M., Raza, A., Waseem, A., Sadia, S., Mushtaq, M. R., Siddiqui, S., Shabbir, H., & Sarker, P. (2025) · Cureus · doi:10.7759/cureus.92705 · Cited by 1 · see citing works
Myerson, M. L., Warden, B. A., Saseen, J. J., & Paparodis, R. D. (2025) · Journal of the American Heart Association · doi:10.1161/jaha.125.044134 · Cited by 1 · see citing works
Self-citationWarden, B. A., & Duell, P. B. (2025) · Journal of clinical lipidology · doi:10.1016/j.jacl.2025.10.065 · Cited by 1 · see citing works
Self-citationZuin, M., & Bilato, C. (2025) · Internal and Emergency Medicine · doi:10.1007/s11739-025-04234-5 · Cited by 1 · see citing works
Guo, P., Yu, X., Wei, X., Xiong, X., & Jiang, J. (2025) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001785 · Cited by 1 · see citing works
Silverman-Lloyd, L. G., Sathiyakumar, V., Huynh, P. P., Chang, B., Pletcher, M. J., Halpern, J., Ivey, S. L., & Martin, S. S. (2026) · Journal of clinical lipidology · doi:10.1016/j.jacl.2025.12.026 · Cited by 1 · see citing works
Zárate-Correa, L. C., García-Peña, Á. A., Kaiser, S. E., Aguilar-Salinas, C. A., Méndez-Castillo, M., Mehta, R., Valério, C. M., Moreira, R. O., Mancillas‐Adame, L. G., Canto, J. A. C., et al. (2026) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2026.120783 · Cited by 1 · see citing works
Regarding: Myasthenia gravis following the initiation of statin therapy
Zeng, S., & Shi, Z. (2026) · Journal of Internal Medicine · doi:10.1111/joim.70122 · Cited by 1 · see citing works
Somers, T., Allard, N. A. E., Siddiqi, S., Janssen, M. C. M., Hopman, M. T. E., Morshuis, W. J., Rüssel, F. G. M., Timmers, S., & Schirris, T. J. J. (2023) · Scientific Reports · doi:10.1038/s41598-023-36741-w · Cited by 1 · see citing works
Гиполипидемическая терапия в особых ситуациях
Арутюнов, Г. П., Владиславович, Е. М., Alieva, A. S., Иосифович, Ш. И., Orlova, Y. A., Koziolova, N. A., Тарловская, Е. И., Григорьева, Н. Ю., & Chesnikova, A. I. (2024) · Атеросклероз и дислипидемии · doi:10.34687/2219-8202.jad.2024.03.0008 · Cited by 1 · see citing works
Tajudin, N. H. M., Fahrni, M. L., Ghani, R. A., Awang, M. H., Chopra, H., & Alkhoshaiban, A. S. (2024) · Journal of Pharmacology and Pharmacotherapeutics · doi:10.1177/0976500x241268964 · Cited by 1 · see citing works
Rationale for Increasing Doses of Statins in Everyday Clinical Practice
Susekov, A. V. (2024) · Kardiologiia · doi:10.18087/cardio.2024.8.n2709 · Cited by 1 · see citing works
Lipidology: The time is now for specialty recognition
Willard, K.-E., Wilson, D. P., Jackson, E. J., Kirkpatrick, C. F., Cheeley, M. K., & Kalra, D. K. (2024) · Journal of clinical lipidology · doi:10.1016/j.jacl.2024.11.002 · Cited by 1 · see citing works
Kulasingam, A., Laustsen, S., Busk, M., Sand, N. P. R., Winther, S., Kragholm, K. H., Hammid, O., Pedersen, K. B., Vedsted, P., Kanstrup, H., et al. (2025) · American Heart Journal · doi:10.1016/j.ahj.2025.04.002 · Cited by 1 · see citing works
Landmesser, U., Laufs, U., Schatz, U., Winzer, E. B., Nowak, B., Kassner, U., Gouni‐Berthold, I., Esteban, A., Lubyayi, L., Krueger, A., et al. (2025) · American Heart Journal · doi:10.1016/j.ahj.2025.05.014 · Cited by 1 · see citing works
When PCSK9 Inhibitors Don’t Save the Day
Soffer, D. E. (2025) · JACC Case Reports · doi:10.1016/j.jaccas.2025.103759 · Cited by 1 · see citing works
Maki, K. C., & Duell, P. B. (2026) · Journal of clinical lipidology · doi:10.1016/j.jacl.2026.02.022 · Cited by 1 · see citing works
Self-citationAebi, P. S., Villoz, F., Bührer, J., Lyko, C., Abolhassani, N., Del Giovane, C., Gencer, B., Rodondi, N., & Blum, M. R. (2025) · PLOS One · doi:10.1371/journal.pone.0338575
“Recent narrative reviews on the management of SAMS found that further research is needed to close the knowledge gap [19].”
Sun, B., Yew, P. Y., Chi, C., Song, M., Loth, M., Liang, Y., Zhang, R., & Straka, R. J. (2023) · medRxiv · doi:10.1101/2023.08.10.23293939
Statine: Nebenwirkungen – alternative Therapieoptionen
Makhmudova, U., & Weingärtner, O. (2024) · Die Kardiologie · doi:10.1007/s12181-024-00669-w
Putri, W. C. C., Sari, M., Wahyuni, F. A., & Suryani, N. (2024) · Acta Holistica Pharmaciana. · doi:10.62857/ahp.v6i1.164
Lee, M., & Safri, A. (2024) · ADCES in Practice · doi:10.1177/2633559x241280315
Statins in the practice of an internal medicine specialist: A review
Susekov, A. V. (2024) · Consilium Medicum · doi:10.26442/20751753.2024.10.202995
Demystifying the nuances of the lipid patient: a guide for primary care providers
Myerson, M. L., Gillett, K., O’Hara, J., Potter, R., & SKOLNIK, N. (2025) · American Journal of Preventive Cardiology · doi:10.1016/j.ajpc.2025.101070
Dietary and nutrient influences on statin-associated muscle symptoms: mechanisms and insights
Ahmadi, A. R., Baghdadi, G., Aziznezhad, H., & Rahimlou, M. (2025) · Academia Nutrition and Dietetics · doi:10.20935/acadnutr7875
Dziewierz, A., Bobrowska, B., Streb, W., Pelliccia, F., Bartuś, S., & Rajtar-Salwa, R. (2025) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2025.2570839
Hofmann, M., Berger, T., & Weiss, P. (2022) · Specialty journal of Pharmacognosy Phytochemistry and Biotechnology · doi:10.51847/wyrmvx9kyk
Pharmacogenomics and Cardiovascular Care for Older Adults
Rowe, C., Delgado, E., Lee, Y. M., Bright, D. R., & Roman, Y. M. (2025) · Springer eBooks · doi:10.1007/978-3-032-10653-7_5
Grant, J. K., Selvam, P. V., Koester, M., Leucker, T. M., & Barth, A. S. (2026) · Journal of clinical lipidology · doi:10.1016/j.jacl.2025.10.002
Chalès, G., Robin, F., & Guggenbuhl, P. (2026) · EMC - Appareil locomoteur · doi:10.1016/s0246-0521(25)47869-3
- Authors
- Warden, B. A., Guyton, J. R., Kovacs, A. C., Durham, J. A., Jones, L. K., Dixon, D. L., Jacobson, T. A., & Duell, P. B.
- Affiliations
- Oregon Health & Science University (US)
- Duke Medical Center (US)
- Virginia Commonwealth University (US)
- Emory University (US)
- Corresponding author
- Warden, Bruce A.
- Guyton, John R.
- Kovacs, Adrienne C.
- Durham, Jessica A.
- Jones, Laney K.
- Dixon, Dave L.
- Jacobson, Terry A.
- Duell, P. Barton
- Venue
- Journal of Clinical Lipidology
- Publisher
- Elsevier BV
- Published
- 2023-01
- Volume
- 17
- Issue
- 1
- Pages
- 19-39
- ISSN
- 1876-4789 (ISSN-L)
- 1933-2874
- OpenAlex
- W4295221059
- Cited by
- 111
- References
- 82
- Citations by year
- 2026: 24 · 2025: 40 · 2024: 24 · 2023: 21 · 2022: 2
- FWCI
- 20.88
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of clinical lipidology (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Cancer, Lipids, and Metabolism
- Keywords
- statin-associated muscle symptoms, statin intolerance, statin discontinuation, cardiovascular risk, medication adherence, lifestyle intervention, statin dose reduction, non-statin therapy, cardiovascular risk reduction
- MeSH terms
- Humans, Lipids, Muscles, Muscular Diseases, Risk Factors, Hydroxymethylglutaryl-CoA Reductase Inhibitors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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