Cited by 381COVID-19 and Mental HealthLong-Term Effects of COVID-19Maternal Mental Health During Pregnancy and Postpartum

The DOI matches its Crossref record; 72 of the 79 references it cites were found in a registry or an index; none of the 48 sources its claims cite is checked for support yet.

Long-term effects of COVID-19 on mental health: A systematic review

Open access

Abstract

Background Acute effects of COVID-19 can be life-threatening. Alterations in mental health during the active infection have been documented, but the long-term consequences are less clear. Method A systematic review was undertaken to investigate the effect of COVID-19 infection on long-term mental health outcomes. Three databases [PubMed, Medline (Ovid) and Cochrane library] were searched between 1st October 2019 and 29th August 2021 with additional hand searching to identify all published studies reporting symptoms of generalised anxiety, depression, post-traumatic stress disorder (PTSD), or sleep disturbance in participants at least one month after COVID-19 infection. The prevalence and mean symptom score of each were assessed. Results Eight hundred and eighty five studies were found, of which 33 were included in the review involving a total of 6743 participants. The studies’ risk of bias were typically fair quality. The median study age of participants was 57.8 years (IQR 49.3–60.7), with 63.0% male (IQR 57.0%–73.0%). Participants typically experienced no or mild symptoms of long-term anxiety (GAD-7, STAI-S, HADS) and depression (PHQ-9, BDI, PHQ-2, HADS). Prevalence varied depending on the measurement tool. Sleep disturbances (primarily insomnia) were most commonly reported as mild. PTSD prevalence was similar to anxiety and depression. Conclusion The overall effect of the pandemic has been linked with worsening psychiatric symptoms. However, the long-term effect from direct COVID-19 infection has been associated with no or mild symptoms. Studies exhibited the long-term prevalence of anxiety, depression, PTSD, and sleep disturbances to be comparable to general population levels.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.jad.2021.11.031

Cites

72 of 72 references verified0 citation errors · 0 not checkable

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Nothing to recompute.

Verification

Claims the paper makes

46 Not checked yet · 23 Own result · 14 Own interpretation · 10 Own method · 6 No basis given

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  • It may state two separate claims as one. 17
  • Probably not a substantial claim. 12
24 of 24
  • The paper relies on this without support.

    The findings from adult hospital or treatment-centre samples can be generalised to COVID-19 survivors outside those settings.

    “All studies examined an adult sample from treatment centres or hospitals.”
  • The paper relies on this without support.

    Mental health symptoms measured at follow-up are attributable to direct COVID-19 infection rather than to indirect pandemic effects.

    “However, the long-term effect from direct COVID-19 infection has been associated with no or mild symptoms.”
  • The paper relies on this without support.

    General-population mental health levels during the pandemic provide a valid benchmark for long-term mental health after COVID-19 infection.

    “Studies exhibited the long-term prevalence of anxiety, depression, PTSD, and sleep disturbances to be comparable to general population levels.”
  • The paper relies on this without support.

    The COVID-19 pandemic overall has been associated with worsening psychiatric symptoms.

    “The overall effect of the pandemic has been linked with worsening psychiatric symptoms.”
  • The paper relies on this without support.

    The PCL-5, TSQ, DTS, and IES-R instruments provide comparable measures of PTSD.

    “As for PTSD, overall PCL-5 and TSQ scores were lower compared to DTS and IES-R scores.”
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Citations

Cites

Show all 79 references

Research works printed but not linked: 3

  1. Darley, 2021, Persistent symptoms up to four months after community and hospital-managed SARS-CoV-2 infection, The Medical Journal of Australia, 10.5694/mja2.50963 · DOI
  2. Hasan, 2021, Mental Health of the COVID-19 Patients in Bangladesh. Mymensingh medical journal, MMJ, 30, 189
  3. Yu, 2020, Prevalence of sleep disturbances during COVID-19 outbreak in an urban Chinese population: a cross-sectional study, Sleep Med., 74, 18, 10.1016/j.sleep.2020.07.009 · DOI

Cited by

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Items 201–300 of 381

Metadata

Authors
Bourmistrova, N. W., Solomon, T., Braude, P., Strawbridge, R., & Carter, B.
Affiliations
  • King's College London (GB)
  • North Bristol NHS Trust (GB)
Corresponding author
Carter, Ben
Venue
Journal of Affective Disorders
Publisher
Elsevier BV
Published
2022-02
Volume
299
Pages
118-125
ISSN
0165-0327 (ISSN-L)
OpenAlex
W3213906311
Cited by
369
References
79
Citations by year
2026: 32 · 2025: 68 · 2024: 79 · 2023: 121 · 2022: 69
FWCI
8.93
Type
journal article
Language
en
Open access
Locations
  • Journal of Affective Disorders (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
  • Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Keywords
COVID-19 pandemic, long-term psychological effects, post-COVID-19 mental health, generalized anxiety disorder, depression, post-traumatic stress disorder, sleep disorders, insomnia
MeSH terms
COVID-19, SARS-CoV-2, Anxiety, Depression, Female, Humans, Male, Mental Health, Middle Aged, Pandemics

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