End-of-Life Care Preferences in Patients with Severe and Persistent Mental Illness and Chronic Medical Conditions: A Comparative Cross-Sectional Study
Abstract
Objectives Physicians rarely engage severe and persistent mental illness (SPMI) patients in end-of-life care discussion despite an increased risk of debilitating medical illnesses and mortality. Access to quality palliative care and medical assistance in dying (MAID) has become a priority in Canada and many jurisdictions. In this study, we compared SPMI and chronic medically ill (CMI) patients' end-of-life care preferences and comfort level with end-of-life care discussion, and identified potential predictors of interest in MAID.Design Comparative cross-sectional study.Setting Hospital-based.Participants We recruited 106 SPMI and 95 CMI patients at the Jewish General Hospital, Canada. Patients aged ≥40 years, without severe cognitive impairment, able to communicate in English or French and provide written informed consent were included.Measurements Attitudes towards pain management, palliative sedation, MAID, and artificial life support were collected with the Health Care Preferences Questionnaire. Adjusted odd ratios (aOR) were calculated for each end-of-life care intervention. Comfort with discussion was rated on a Likert scale. A stepwise regression analysis was performed to identify predictors of interest in MAID.Results SPMI was not correlated to any end-of-life care intervention, except for MAID where SPMI patients were less likely to support its use (aOR: 0.48, 95% CI: 0.25-0.94, p = 0.03). Religiosity was also correlated with interest in MAID (aOR: 0.14, 95% CI: 0.06-0.31, p < 0.001). Patients in both groups were comfortable talking about end-of-life care.Conclusions SPMI patients are able to voice their end-of-life care preferences, and contrary to some fears, do not want MAID more than CMI patients.
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Empirical comparisons of patients with severe and persistent mental disorder and those with chronic physical disease show similar end-of-life values, including preferences regarding artificial life support and relief of suffering.
“Empirical comparisons of patients with severe and persistent mental disorder and those with chronic physical disease show similar end-of-life values, including preferences regarding artificial life support and relief of suffering.32”
From Medical Assistance in Dying for the Sole Underlying Condition of Mental Disorder (MAiD MD-SUMC): an analysis and qualitative evidence synthesis (2026) · cites this paper as [32]
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- Authors
- Elie, D., Marino, A., Torres-Platas, S. G., Noohi, S., Semeniuk, T., Segal, M., Looper, K. J., & Rej, S.
- Affiliations
- Jewish General Hospital (CA)
- Venue
- The American Journal of Geriatric Psychiatry
- Publisher
- Elsevier BV
- Published
- 2018-01
- Volume
- 26
- Issue
- 1
- Pages
- 89-97
- ISSN
- 1064-7481 (ISSN-L)
- OpenAlex
- W2756595785
- Semantic Scholar
- 7c9753d0e4a7d591636619728118793cffed76f5
- Cited by
- 44
- References
- 40
- Citations by year
- 2026: 6 · 2025: 3 · 2024: 5 · 2023: 3 · 2022: 8 · 2021: 5 · 2020: 6 · 2019: 6 · 2018: 1 · 2017: 1
- FWCI
- 3.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Geriatric Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- McGill Faculty of Medicine
- Canadian Institute for Health Research
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Keywords
- end-of-life preferences, severe and persistent mental illness, chronic disease, medical assistance in dying, palliative care, palliative sedation, artificial life support, pain management, end-of-life discussions, religiosity
- MeSH terms
- Aged, Mental Disorders, Canada, Chronic Disease, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Religion and Psychology, Terminal Care, Suicide, Assisted, Patient Preference
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