Neurocognitive Correlates of Resilience in Late-Life Depression
Open accessAbstract
Objective Increasing understanding of the neurocognitive correlates of resilience in late-life depression (LLD) could inform interventions to promote more sustained remission. We investigated cross-sectional relations between baseline resilience and domains of neurocognitive functioning in depressed older adults enrolled in one of four trials.Methods Participants (N = 288) completed neurocognitive tests of memory, language performance, and executive functioning as well as measures of subjective memory performance and components of resilience (grit, active coping self-efficacy, accommodative coping self-efficacy, and spirituality).Results Medium-sized associations were observed between greater resilience (overall resilience, accommodative coping) and lower frequency of self-reported forgetting. Small positive associations were observed between language performance and total resilience, active coping self-efficacy, and accommodative coping self-efficacy. Small negative associations were observed between spirituality and each objective measure of cognitive performance.Conclusion Future longitudinal studies will help elucidate the complex relation between resilience and cognitive functioning in LLD. In addition, randomized controlled trials targeting coping self-efficacy may inform the development of more effective and personalized interventions.
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Self-reported resilience is significantly associated with language performance among adults with LLD.
“A recent study found significant associations between self-reported resilience and language performance among 288 adults with LLD123.”
From Psychobiological factors of resilience and depression in late life (2019) · cites this paper as [123]
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Influential
- Authors
- Laird, K. T., Lavretsky, H., Wu, P., Krause, B., & Siddarth, P.
- Affiliations
- University of California, Los Angeles (US)
- Corresponding author
- Lavretsky, Helen
- Venue
- The American Journal of Geriatric Psychiatry
- Publisher
- Elsevier BV
- Published
- 2019-01
- Volume
- 27
- Issue
- 1
- Pages
- 12-17
- ISSN
- 1064-7481 (ISSN-L)
- PMC
- PMC6298796
- OpenAlex
- W2888472981
- Cited by
- 14
- References
- 29
- Citations by year
- 2025: 1 · 2023: 5 · 2022: 4 · 2021: 2 · 2019: 1 · 2018: 1
- FWCI
- 1.18
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Geriatric Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH (AT008383, AT009198, MH077650, MH097892)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Resilience and Mental Health
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Keywords
- resilience, geriatric depression, neurocognitive function, older adults, coping self-efficacy, active coping, spirituality, memory, language performance, executive function, subjective memory complaints, depression remission
- MeSH terms
- Adaptation, Psychological, Aged, Aged, 80 and over, Aging, Cross-Sectional Studies, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Self Efficacy, Spirituality, Resilience, Psychological, Cognitive Dysfunction
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