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Cited by 258

The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

Risk and Protective Factors for Childhood Asthma: What Is the Evidence?

Open access
Castro-Rodriguez, Jose A., Forno, Erick, Rodriguez-Martinez, Carlos E., Celedón, Juan C.·2016·The Journal of Allergy and Clinical Immunology: In Practice

Abstract

In order to summarize the principal findings on risk and protective factors for childhood asthma, we retrieved systematic reviews on these topics in children (ages 1 to 18 years), up to January 2016, through MEDLINE, EMBASE, CINAHL, SCOPUS and CDSR. Two hundred twenty seven studies were searched from databases. Among those, 41 systematic reviews (SRs) were included: 9 focused on prenatal factors, 5 on perinatal factors, and 27 on postnatal factors. Of these 41 SRs, 83% had good methodological quality, as determined by the AMSTAR tool. After reviewing all evidence, parental asthma, prenatal environmental tobacco smoke and prematurity (particularly very preterm birth) are well-established risk factors for childhood asthma. Current findings do suggest mild to moderate causal effects of certain modifiable behaviors or exposures during pregnancy (maternal weight gain or obesity, maternal use of antibiotics or paracetamol, and maternal stress), the perinatal period (birth by Caesarean delivery), or postnatal life (severe RSV infection, overweight or obesity, indoor exposure to mold or fungi, and outdoor air pollution) on childhood asthma, but this suggestive evidence must be confirmed in interventional studies or (if interventions are not feasible) well-designed prospective studies.

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Metadata

Authors
Castro-Rodriguez, J. A., Forno, E., Rodriguez-Martinez, C. E., & Celedón, J. C.
Venue
The Journal of Allergy and Clinical Immunology: In Practice
Publisher
Elsevier BV
Published
2016-11
Volume
4
Issue
6
Pages
1111-1122
ISSN
2213-2198 (ISSN-L)
OpenAlex
W2409013167
Cited by
258
References
48
FWCI
12.09
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Risk and Protective Factors for Childhood Asthma: What Is the Evidence? https://app.cochat.ai/papers/10.1016/j.jaip.2016.05.003
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Castro-Rodriguez, J. A., Forno, E., Rodriguez-Martinez, C. E., & Celedón, J. C. (2016). Risk and Protective Factors for Childhood Asthma: What Is the Evidence? The Journal of Allergy and Clinical Immunology: In Practice. https://doi.org/10.1016/j.jaip.2016.05.003

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.