The DOI matches its Crossref record; 261 of the 261 references it cites were found in a registry or an index.
Smoking and increased Alzheimer's disease risk: A review of potential mechanisms
Open accessAbstract
Background: Cigarette smoking has been linked with both increased and decreased risk for Alzheimer's disease (AD). This is relevant for the US military because the prevalence of smoking in the military is approximately 11% higher than in civilians. Methods: A systematic review of published studies on the association between smoking and increased risk for AD and preclinical and human literature on the relationships between smoking, nicotine exposure, and AD‐related neuropathology was conducted. Original data from comparisons of smoking and never‐smoking cognitively normal elders on in vivo amyloid imaging are also presented. Results: Overall, literature indicates that former/active smoking is related to a significantly increased risk for AD. Cigarette smoke/smoking is associated with AD neuropathology in preclinical models and humans. Smoking‐related cerebral oxidative stress is a potential mechanism promoting AD pathology and increased risk for AD. Conclusions: A reduction in the incidence of smoking will likely reduce the future prevalence of AD.
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Alzheimer’s disease: risk factors and potentially protective measures
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The Epidemiology of Alzheimer's Disease Modifiable Risk Factors and Prevention
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Alzheimer’s disease prevention: from risk factors to early intervention
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Metadata
- Authors
- Durazzo, T. C., Mattsson, N., Weiner, M. W., & Initiative, A. D. N.
- Venue
- Alzheimer's & Dementia
- Publisher
- Wiley
- Published
- 2014-06
- Volume
- 10
- Issue
- 3S
- Pages
- S122-45
- ISSN
- 1552-5260 (ISSN-L)
- 1552-5279
- OpenAlex
- W2142529576
- Cited by
- 451
- References
- 261
- FWCI
- 14.60
- Type
- journal article
- Language
- en
- Open access
- hybrid
- Funders
- National Institutes of Health (DA24136)
- National Institute on Aging (U01 AG024904)
- National Institute of Biomedical Imaging and Bioengineering
- Abbott Laboratories
- AstraZeneca
- Bristol-Myers Squibb Foundation
- Elan
- Genentech
- GE Healthcare
- GlaxoSmithKline
- Innogenetics
- Johnson and Johnson
- Eli Lilly and Company
- Medpace
- Merck Company Foundation
- Novartis
- Pfizer
- Roche
- Schering-Plough
- Synarc
- Wyeth
- Alzheimer's Association
- U.S. Food and Drug Administration
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- Durazzo, T. C., Mattsson, N., Weiner, M. W., & Initiative, A. D. N. (2014). Smoking and increased Alzheimer's disease risk: A review of potential mechanisms. Alzheimer's & Dementia. https://doi.org/10.1016/j.jalz.2014.04.009
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
