Dysregulation of lipids in Alzheimer’s disease and their role as potential biomarkers

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

Folch, J., Lees, M., & Stanley, G. H. S. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64849-5 · Cited by 65,189

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., & Pericak-Vance, M. A. (1993) · Science · doi:10.1126/science.8346443 · Cited by 9,429

Metabolite profiles and the risk of developing diabetes

Wang, T. J., Larson, M. G., Vasan, R. S., Cheng, S., Rhee, E. P., McCabe, E., Lewis, G. D., Fox, C. S., Jacques, P. F., Fernandez, C., et al. (2011) · Nature Medicine · doi:10.1038/nm.2307 · Cited by 3,143

Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics

Matyash, V., Liebisch, G., Kurzchalia, T. V., Shevchenko, A., & Schwudke, D. (2008) · Journal of Lipid Research · doi:10.1194/jlr.d700041-jlr200 · Cited by 2,633

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

Sreekumar, A., Poisson, L., Rajendiran, T. M., Khan, A. P., Cao, Q., Yu, J., Laxman, B., Mehra, R., Lonigro, R. J., Li, Y., et al. (2009) · Nature · doi:10.1038/nature07762 · Cited by 2,269

Update of the LIPID MAPS comprehensive classification system for lipids

Fahy, E., Subramaniam, S., Murphy, R. C., Nishijima, M., Raetz, C. R. H., Shimizu, T., Spener, F., van Meer, G., Wakelam, M. J. O., & Dennis, E. A. (2009) · Journal of Lipid Research · doi:10.1194/jlr.r800095-jlr200 · Cited by 1,628

Ion Suppression in Mass Spectrometry

Annesley, T. M. (2003) · Clinical Chemistry · doi:10.1373/49.7.1041 · Cited by 1,598

Human ApoE isoforms differentially regulate brain amyloid-β peptide clearance

Castellano, J. M., Kim, J., Stewart, F. R., Jiang, H., DeMattos, R. B., Patterson, B. W., Fagan, A. M., Morris, J. C., Mawuenyega, K. G., Cruchaga, C., et al. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3002156 · Cited by 1,242

Shotgun lipidomics: Electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples

Han, X., & Gross, R. W. (2004) · Mass Spectrometry Reviews · doi:10.1002/mas.20023 · Cited by 1,126

The intestinal microbiota exerts a sex-specific influence on neuroinflammation in a Parkinson's disease mouse model

Zhou, X., Gao, Y. J., Wei, J., Luo, J., Wang, Y., Yue, M., Wang, B., Hong, D., Chen, T., & Fang, X. (2023) · Neurochemistry International · doi:10.1016/j.neuint.2023.105661 · Cited by 15

Causal effect of blood osteocalcin on the risk of Alzheimer’s disease and the mediating role of energy metabolism

Guo, X., Yang, Y., Zhou, R., Tian, G., Shan, C., Liu, J., & Li, R. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-02924-w · Cited by 15

Regional Lipid Expression Abnormalities Identified Using MALDI IMS Correspond to MRI-Defined White Matter Hyperintensities within Post-mortem Human Brain Tissues

Pinsky, W., Harris, A. J., Roseborough, A. D., Wang, W., KHAN, A. R., Jurčić, K., Yeung, K. K. ‐., Pasternak, S., & Whitehead, S. N. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.0c05017 · Cited by 14

Exploring the significance of lipids in Alzheimer's disease and the potential of extracellular vesicles

Su, H., Masters, C. L., Bush, A. I., Barnham, K. J., Reid, G. E., & Vella, L. J. (2023) · PROTEOMICS · doi:10.1002/pmic.202300063 · Cited by 13

Multimodal mass spectrometry imaging for plaque- and region-specific neurolipidomics in Alzheimer’s disease mouse models

Trinklein, T. J., Rubakhin, S. S., Okyem, S., Croslow, S. W., Asadian, M., Sabitha, K. R., Lazarov, O., Lam, F., & Sweedler, J. V. (2025) · Nature Communications · doi:10.1038/s41467-025-65956-w · Cited by 17

Analytical techniques for biomass-restricted metabolomics: An overview of the state-of-the-art

He, B., Zhang, W., Guled, F., Harms, A. C., Ramautar, R., & Hankemeier, T. (2021) · Microchemical Journal · doi:10.1016/j.microc.2021.106794 · Cited by 13

Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer’s Disease Mouse Model

Zamarbide, M., Martínez‐Pinilla, E., Gil-Bea, F. J., Yanagisawa, M., Franco, R., & Pérez‐Mediavilla, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23073533 · Cited by 13

Fundamental neurochemistry review: Old brain stories ‐ Influence of age and sex on the neurodegeneration‐associated lipid changes

Cuenca‐Bermejo, L., Prinetti, A., Kublickiene, K. R., Raparelli, V., Kautzky‐Willer, A., Norris, C. M., Pilote, L., & Herrero, M. T. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15834 · Cited by 15

First insights into region-specific lipidome alterations of prefrontal cortex and hippocampus of mice exposed chronically to microcystins

He, J., Chen, Y., Dai, S., Chen, F., Wang, Y., Shi, T., Chen, L., Liu, Y., Chen, J., & Xie, P. (2023) · Environment International · doi:10.1016/j.envint.2023.108018 · Cited by 12

The comprehensive mechanism underlying Schisandra polysaccharide in AD-like symptoms of Aβ25-35-induced rats based on hippocampal metabolomics and serum lipidomics techniques

Zhao, S., Zhang, J., Chen, Y., Cui, X., Liu, H., Yan, Y., Sun, Y., Yong-xiu, Q., & Liu, Y. (2023) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2023.115717 · Cited by 12

Dynamic functional network connectivity and its association with lipid metabolism in Alzheimer's disease

Zang, F., Liu, X., Fan, D., He, C., Zhang, Z., Xie, C., & Initiative, A. D. N. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70029 · Cited by 12

Lipids in the Treatment of Neurodegenerative Diseases

Lange, K. W. (2020) · Wiley eBooks · doi:10.1002/047167849x.bio118 · Cited by 12

Genistein ameliorates glucose-induced β-amyloid toxicity, oxidative stress, and aging in the C. elegans model of Alzheimer's disease

Wang, J., Jiang, B., Lin, X., Zhang, J., Xiong, L., Feng, Y., Cheang, W. S., & Xu, B. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.10.263 · Cited by 11

Microglial metabolic reprogramming in Alzheimer's disease: Pathways, mechanisms, and therapeutic implications

Yang, F.-G., Yang, H., Han, S.-W., Wang, J.-T., Gao, W. B., Ye, Q.-Y., Zhang, M.-M., Yu, Y., & Li, H.-L. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103050 · Cited by 11

Unraveling lipid and inflammation interplay in cancer, aging and infection for novel theranostic approaches

Conde-Torres, D., Blanco-González, A., Seco-González, A., Suárez-Lestón, F., Cabezón, A., Antelo-Riveiro, P., Piñeiro, Á., & García‐Fandiño, R. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1320779 · Cited by 13

Dissecting unique and common variance across body and brain health indicators using age prediction

Beck, D., de Lange, A. G., Gurholt, T. P., Voldsbekk, I., Maximov, I. I., Subramaniapillai, S., Schindler, L. S., Hindley, G., Leonardsen, E. H., Rahman, Z., et al. (2024) · Human Brain Mapping · doi:10.1002/hbm.26685 · Cited by 10

Nutritional Lipidomics in Alzheimer’s Disease

Kalli, Ε. G. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-32633-3_14 · Cited by 11

Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice

Puris, E., Kouřil, Š., Najdekr, L., Loppi, S. H., Korhonen, P., Kanninen, K. M., Malm, T., Koıstınaho, J., Friedecký, D., & Gynther, M. (2021) · Scientific Reports · doi:10.1038/s41598-021-92602-4 · Cited by 11

Label-free characterization of Amyloid-β-plaques and associated lipids in brain tissues using stimulated Raman scattering microscopyPreprint

Schweikhard, V., Baral, A., Krishnamachari, V. V., Hay, W. C., & Fuhrmann, M. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/789248 · Cited by 11

Heterogeneous brain abnormalities in subjective cognitive decline converge on a common network and their transcriptional signature

Lan, H., Liu, W., Zuo, C., Chen, L., Wang, S., Luo, C., Kuang, W., Kemp, G. J., Lui, S., Suo, X., et al. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70073 · Cited by 12

Alzheimer’s Disease: Protective Effects of Mycobacterium vaccae, a Soil-Derived Mycobacterium with Anti-Inflammatory and Anti-Tubercular Properties, on the Proteomic Profiles of Plasma and Cerebrospinal Fluid in Rats

Loupy, K. M., Lee, T., Zambrano, C. A., Elsayed, A. I., D’Angelo, H. M., Fonken, L. K., Frank, M. G., Maier, S. F., & Lowry, C. A. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200568 · Cited by 10

Brain and serum lipidomic profiles implicate Lands cycle acyl chain remodeling association with APOEε4 and mild cognitive impairment

Mares, J. A., Costa, A. P., Dartora, W. J., Wartchow, K. M., Lazarian, A., Bennett, D. A., Nuriel, T., Menon, V., & McIntire, L. B. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1419253 · Cited by 10

Developmental brain lipidomics is influenced by postnatal chlorpyrifos exposure and APOE genetic background in mice

Guardia-Escote, L., Biosca-Brull, J., Cabré, M., Blanco, J., Mladenova-Koleva, M., Basaure, P., Pérez-Fernández, C., Sánchez-Santed, F., Domingo, J. L., & Colomina, M. T. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03555-8 · Cited by 9

Brain areas lipidomics in female transgenic mouse model of Alzheimer's disease

Ferré‐González, L., Balaguer, Á., Roca, M., Ftara, A., Lloret, A., & Cháfer‐Pericás, C. (2024) · Scientific Reports · doi:10.1038/s41598-024-51463-3 · Cited by 9

Impact of APOE on cerebrovascular lipid profile in Alzheimer’s disease

Inoue, Y., Wang, H., Heckman, M. G., Ren, Y., White, L. J., Lü, W., Wang, P., Julia, T. C. W., Koga, S., Alnobani, A., et al. (2025) · Acta Neuropathologica · doi:10.1007/s00401-025-02949-5 · Cited by 9

Lipidomic Network of Mild Cognitive Impairment from the Mayo Clinic Study of Aging

Wang, X., Bui, H. H., Vemuri, P., Graff‐Radford, J., Jack, C. R., Petersen, R. C., & Mielke, M. M. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201347 · Cited by 9

Simvastatin Blocks Reinstatement of Cocaine-induced Conditioned Place Preference in Male Mice with Brain Lipidome Remodeling

Xu, W., He, Y., Zhang, J., Li, H., Wan, X., Li, M., Wang, Y., Xu, R., Zhang, H., Dai, Y., et al. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00771-z · Cited by 8

Plasma lipidomic fingerprinting enables high-accuracy biomarker discovery for Alzheimer’s disease: a targeted LC-MRM/MS approach

Gao, X., Cheng, X., Chen, P., Lin, L., Wang, X., Xu, R., Shen, H., & Yang, Q. (2025) · GeroScience · doi:10.1007/s11357-025-01777-5 · Cited by 8

Integrated Gut Microbiota, Metabolomics, and Network Pharmacology to Investigate the Anti-Alzheimer’s Mechanism of Tripterygium Glycoside

Zhang, Y., Silang, Q., Wang, T., Wang, N., Gesang, L., Tang, L., & Liu, L. (2025) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s537129 · Cited by 8

Astrocytic functions and lipid metabolism: Correlations and therapeutic targets in Alzheimer's disease and glioblastoma

Zhang, X., Gao, R., Yang, L., Zhu, Y., Zhang, T., Shen, X., Gu, W., Yang, L., & Peng, S. (2024) · Clinical and Translational Discovery · doi:10.1002/ctd2.287 · Cited by 8

Effects of Sevoflurane Anesthesia on Cerebral Lipid Metabolism in the Aged Brain of Marmosets and Mice

Mao, H., Zhu, J., Cheng, Y., Shi, L., Chen, X., Zhou, R., Xue, Z., Liu, S., Qiu, Z., & Jiang, H. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.915570 · Cited by 7

Exploration of Plasma Lipids in Mild Cognitive Impairment due to Alzheimer’s Disease

Bergland, A. K., Proitsi, P., Kirsebom, B., Soennesyn, H., Hye, A., Larsen, A. I., Xu, J., Legido‐Quigley, C., Rajendran, L., Fladby, T., et al. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200441 · Cited by 6

Altered Expression Profile of Phosphatidylinositols in Erythrocytes of Alzheimer’s Disease and Amnestic Mild Cognitive Impairment Patients

Chen, Y., Lin, C., Guo, Z., Zhao, S., Zhu, Y., Huang, F., Shui, G., Lam, S. M., Pu, J., Yan, Y., et al. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190926 · Cited by 8

Interfacial Electromigration for Analysis of Biofluid Lipids in Small Volumes

Edwards, M. E., Freitas, D. P., Hirtzel, E. A., White, N., Wang, H., Davidson, L. A., Chapkin, R. S., Sun, Y., & Yan, X. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.3c04309 · Cited by 6

Advantages of using biologically generated 13 C-labelled multiple internal standards for stable isotope-assisted LC-MS-based lipidomics

Jaber, M. A., de Falco, B., Abdelrazig, S., Ortori, C. A., Barrett, D. A., & Kim, D. (2023) · Analytical Methods · doi:10.1039/d3ay00460k · Cited by 6

Chemical Derivatization-Aided High Resolution Mass Spectrometry for Shotgun Lipidome Analysis

Hofferek, V., Su, H., & Reid, G. E. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1410-5_5 · Cited by 6

Aβ1-42 peptide toxicity on neuronal cells: A lipidomic study

Davani, L., Fu, X., Simone, A. D., Li, P., Montanari, S., Lämmerhofer, M., & Andrisano, V. (2022) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2022.114876 · Cited by 5

Gemfibrozil-Induced Intracellular Triglyceride Increase in SH-SY5Y, HEK and Calu-3 Cells

Bachmann, C. M., Janitschke, D., Lauer, A. A., Erhardt, T., Hartmann, T., Grimm, M. O. W., & Grimm, H. S. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032972 · Cited by 5

An insight into structure-activity relationship of naturally derived biological macromolecules for the treatment of Alzheimer’s disease: a review

Halder, D., Das, S., & Joseph, A. (2023) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2023.2230279 · Cited by 6

Clinical advances in analytical profiling of signature lipids: implications for severe non-communicable and neurodegenerative diseases

Sarkar, S., Roy, D., Chatterjee, B., & Ghosh, R. (2024) · Metabolomics · doi:10.1007/s11306-024-02100-7 · Cited by 6

Association of lipid levels with motor and cognitive function and decline in Parkinson's disease

Gu, L., Shu, H., Wang, Y., Li, H., & Wang, P. (2024) · Psychogeriatrics · doi:10.1111/psyg.13122 · Cited by 5

N -Glycan profile of the cell membrane as a probe for lipopolysaccharide-induced microglial neuroinflammation uncovers the effects of common fatty acid supplementation

Grijaldo-Alvarez, S. J. B., Alvarez, M. R., Schindler, R. L., Oloumi, A., Hernandez, N., Seales, T., Angeles, J. G. C., Nacario, R. C., Completo, G. C. J., Zivkovic, A. M., et al. (2024) · Food & Function · doi:10.1039/d4fo01598c · Cited by 5

Integrated untargeted and targeted metabolomics to reveal the mechanisms of herbal medicine HLXLD on Alzheimer's disease

Zhou, W., Tian, L., Wang, X., Hou, G., Yu, J., Chen, M., Xu, C., Xue, L., Tan, X., & Dai, R. (2025) · Journal of Chromatography B · doi:10.1016/j.jchromb.2025.124746 · Cited by 5

Plasma lipid dysregulation reflecting cerebrospinal fluid profile predicts Alzheimer’s disease progression

Novau-Ferré, N., Panisello, L., García‐González, P., Mateu-Fabregat, J., Cantero, J. L., Atienza, M., Boada, M., Ruiz, A., & Bulló, M. (2025) · Age and Ageing · doi:10.1093/ageing/afaf363 · Cited by 4

Investigation of the structural changes in the hippocampus and prefrontal cortex using FTIR spectroscopy in sleep deprived mice

Sarıbal, D., Çalis, H., Ceylan, Z., Depciuch, J., Cebulski, J., & Güleken, Z. (2024) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2024.124702 · Cited by 5

Plasma lipidomics in early APP/PS1 female mouse model and its relationship with brain: Is it affected by the estrous cycle?

Ferré‐González, L., Balaguer, Á., Roca, M., Ftara, A., Lloret, A., & Cháfer‐Pericás, C. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01549-x · Cited by 4

Mass Spectrometry Applied to Human Cerebrospinal Fluid Lipidome

Millán, L., Fernández‐Irigoyen, J., Santamaría, E., & Mayo, R. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9706-0_23 · Cited by 4

Mapping the causal chain from genetic risk variants to lipid dysmetabolism in Parkinson’s disease

De-Paula, R. B., Kim, J., Rhinn, H., Saade, H., Chavez, F., Segura, T., Lozano, M. V., Etoundi, M., Silos, K., Kass, N. R., et al. (2026) · Brain · doi:10.1093/brain/awag039 · Cited by 4

Rapid Characterization of Phospholipids from Biological Matrix Enabled by Indium Tin Oxide (ITO) Coated Slide Assisted Enrichment MALDI Mass Spectrometry

Huang, P., Zhang, H., Liu, Y., & Li, L. (2024) · Analysis & Sensing · doi:10.1002/anse.202300097 · Cited by 3

Mitochondrial related Mendelian randomization identifies causal associations between metabolic disorders and childhood neurodevelopmental disorders

Hu, C., Li, J., Heng, P., & Luo, J. (2024) · Medicine · doi:10.1097/md.0000000000040481 · Cited by 4

Factorial-Design-Based Optimization of a Commercial MALDI-2 timsTOF Mass Spectrometer for Lipid Analysis

Croslow, S. W., Sirois, C. H., & Sweedler, J. V. (2025) · Journal of the American Society for Mass Spectrometry · doi:10.1021/jasms.4c00424 · Cited by 3

Lipids, brain ageing, dementia, and lipidomics

Poljak, A., Braidy, N., Wong, M. W. K., Liu, Y., Housseini, M., & Sachdev, P. S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815854-8.00012-4 · Cited by 3

Integrated approach on UPLC-QTOF/MS based active plasma component and metabolomics analysis of Gan Mai Da Zao decoction on the treatment of Alzheimer's disease in rats plasma and urine

Cui, M., Wang, J., Zhang, Y., Chen, J., Mou, T., Zhang, C., Gu, S., Zhao, T., Sun, Y., Hao, W., et al. (2022) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2022.103879 · Cited by 3

Investigating a Novel Neurodegenerative Disease Toxic Mechanism Involving Lipid Binding Specificity of Amyloid Oligomers

Hirschbeck, S. S., Lindberg, E. T., Jang, J. H., Jacob, M. R., Cantrell, K. L., & Do, T. D. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00830 · Cited by 3

Quantitative Assays of Plasma Apolipoproteins

Poljak, A., Duncan, M. W., Jayasena, T., & Sachdev, P. S. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0471-7_3 · Cited by 3

Understanding the pathophysiology of alzheimer's disease

Alharbi, S. S., Alharbi, S. S., Alanazi, A. F., & Alomran, R. W. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns10.15185 · Cited by 2

Unexpected links between metabolic syndrome, cognitive deficit, astrocyte dysfunction and brain glymphatic activity: general patterns and relationships

Shirolapov, I. V., Zakharov, A. V., Pavlova, O. N., Borisova, O. V., Bulgakova, S. V., & Kurmaev, D. P. (2025) · Экспериментальная и клиническая гастроэнтерология · doi:10.31146/1682-8658-ecg-235-3-44-54 · Cited by 2

Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study

Napolitano, E., Marino, C., Grimaldi, M., Buonocore, M., Santoro, A., & D’Ursi, A. M. (2026) · NMR in Biomedicine · doi:10.1002/nbm.70255 · Cited by 2

Lipids and carotenoids may influence the neuropathology of Alzheimer's disease: A meta-analysis

Tiwari, A., Gautam, A. S., Panda, E. S., & Singh, R. K. (2024) · Archives of Gerontology and Geriatrics Plus · doi:10.1016/j.aggp.2024.100072 · Cited by 2

CE(20:4) and CE(22:5) cholesteryl ester levels are elevated in the plasma of Alzheimer’s disease patients with ε3/ε4 genotype

Stefanini, E., Serrano‐Marín, J., Iglesias, A., Fernández, M. G., Sánchez-Navés, J., Alkozi, H. A., Bernal‐Casas, D., & Franco, R. (2025) · Exploration of Neuroprotective Therapy · doi:10.37349/ent.2025.100497 · Cited by 3

Proteomic and metabolomic biomarkers of Alzheimer's disease: Opportunities to advance precision medicine and clinical trials

Petersen, M. E., Gross, T. J., O’Bryant, S. E., & Mapstone, M. E. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-818845-3.00018-9 · Cited by 2

Dietary Neurolipidomics in Alzheimer's Disease

Kalli, Ε. G., & Vlamos, P. (2022) · Journal of Nutritional Medicine and Diet Care · doi:10.23937/2572-3278/1510058 · Cited by 2

Pipeline of Mass-spectrometry Data Processing for Diagnostic Molecular Marker Panel Obtaining Using the Example of Search Markers of Breast Cancer Metastasis

Tokareva, A., Chagovets, V. V., Kononikhin, A. S., Starodubtseva, N. L., Евгеньевич, Ф. В., & Николаев, Е. Н. (2021) · Biomedical Chemistry Research and Methods · doi:10.18097/bmcrm00156 · Cited by 2

Astrocyte, Lipid Metabolism in Alzheimer’s Disease and Glioblastoma

(2022) · doi:10.31038/jcrm.2022555 · Cited by 1

Differential gene expression of blood-based ABCA9, CNOT8, SESN1, UCP3, MAP2K1 and DDIT4 in Alzheimer’s disease

Samsudin, A. Z., Ramasamy, K., Lim, S. M., Chin, A., Tan, M. P., Kamaruzzaman, S. B., Ibrahim, B., & Majeed, A. B. A. (2023) · Neuroscience Research Notes · doi:10.31117/neuroscirn.v6i4.262 · Cited by 1

The role of lipid species in Alzheimer’s disease onset: A comprehensive Mendelian randomization analysis

Wang, W., & Xia, H. (2024) · Brain Research · doi:10.1016/j.brainres.2024.149238 · Cited by 1

Integrative analysis of cerebrospinal fluid biomarkers, metabolomics, and polygenic risk reveals novel metabolite associations with Alzheimer's disease

Francia, M., Ramesh, N., Boltz, T. A., Bot, M. H. M., van der Flier, W. M., Visser, P. J., van der Lee, S. J., Teunissen, C. E., Pijnenburg, Y. A. L., den Braber, A., et al. (2025) · Journal of Alzheimer s Disease · doi:10.1177/13872877251389924 · Cited by 2

Blood–Brain Barrier Permeability in Cases of Post-operative Delirium Is Associated with Central Nervous System Phosphatidylcholine Imbalances

Jung, M., Pan, X., Sweeney, A., Passmore, A. P., McGuinness, B., McAuley, D. F., Beverland, D., Heslegrave, A., Schott, J. M., Zetterberg, H., et al. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-05847-3 · Cited by 1

Lipid Dynamics in the Amyloid Cascade Hypothesis: Evaluating the Biological Relevance of In Vitro Models

Serravalle, S., Lolicato, F., Tempra, C., Pannuzzo, M., Sciacca, M. F. M., Milardi, D., & Rosa, C. L. (2026) · ChemBioChem · doi:10.1002/cbic.70398 · Cited by 1

Hyperlipid‐Related Alzheimer's Disease: Potential Role of CircUCK2 / miR ‐24‐3p/p38 Axis in Neuronal Damage

Yin, W., Peng, L., Jing-hong, Z., Huang, X., & Yin, W. (2026) · Comprehensive physiology · doi:10.1002/cph4.70146 · Cited by 1

Blood Biomarkers of Cognitive Health and Neurodegenerative Disease

Mapstone, M. E., Gross, T. J., Subramaniam, S., Fiandaca, M. S., & Federoff, H. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108552684.035 · Cited by 1

Maternal fish-oil supplementation reduces presenilin 1 level and the amyloid-beta burden in adult 5xFAD offspring without major changes in brain fatty acids

Milanović, D., Perović, M., Petrović, S., Todorović, S., Prvulović, M., Vukojevic, A., & Mladenović, A. (2024) · Archives of Biological Sciences · doi:10.2298/abs240105001m · Cited by 1

Relationships Between Treatment and Clinical Evaluations

Pardi, P. C., & dos Santos, G. A. A. (2022) · Springer eBooks · doi:10.1007/978-3-030-94383-7_9 · Cited by 1

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De-Paula, R. B., Kim, J., Rhinn, H., Saade, H., Chavez, F. I., Segura, T., Lozano, M. V., Etoundi, M., Silos, K., Korchina, V., et al. (2025) · medRxiv · doi:10.1101/2025.07.14.25331535 · Cited by 1

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Costa, A. C. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.5.2017.tde-11092017-115142

Potential Biomarkers for Alzheimer’s Disease Screened in a Small Brazilian Population

Bonini, J. S., Fermino, B. L., Wouk, J., Fabbri, R., da Silva, W. C. F. N., Vellosa, J. C. R., Patrzyk, L. H., Fiebrantz, A. K. B., & Ivanski, F. (2017) · Hospice and Palliative Medicine International Journal · doi:10.15406/hpmij.2017.01.00022

The relation between human biomarkers and oxidative stress in Alzheimer’s disease, novel in vivo experimental modelling possibilities

Galik-Olah, Z. (2018) · SZTE Repository of Dissertations (University of Szeged) · doi:10.14232/phd.9739

Epigenetic Regulation of Lipid Metabolism in Neural Stem Cell Fate Decision

Syal, C. (2019) · uO Research (University of Ottawa) · doi:10.20381/ruor-22958

Fatty Acyl-Specific Macrolipidomics and Microlipidomics for Nutritional Research

Henao, A., & José, J. (2019) · UWSpace (University of Waterloo)

Neuroinflammation characterizes the earliest changes in Alzheimer’s disease pathology and associated subjective cognitive impairment in adult hydrocephalus biopsiesPreprint

Huang, W., Bartosch, A. M. W., Xiao, H., Flowers, X. E., Leskinen, S., Tomljanovic, Z., Iodice, G. M., Boyett, D. M., Spinazzi, E. F., Menon, V., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.01.322511

Identification of Abnormal Lipid Profiles Promote Cognitive Decline in Alzheimer's Disease Spectrum via Large-Scale Brain ConnectivityPreprint

Wang, Q., Zang, F., He, C., Zhang, Z., & Xie, C. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3904355

Dementia

Bienko, N., Burhanullah, M. H., & Munro, C. A. (2021) · Springer eBooks · doi:10.1007/978-3-030-22009-9_961 · Cited by 1

Dementia

Bienko, N., Burhanullah, M. H., & Munro, C. A. (2019) · Springer eBooks · doi:10.1007/978-3-319-69892-2_961-1 · Cited by 1

Letter

Khachaturian, A. S. (2017) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1016/j.dadm.2017.11.004

The profiling and imaging of sterol molecules in the human brain

Griffiths, L. (2023) · Cronfa (Swansea University) · doi:10.23889/suthesis.62587

Lipidomics in Multi‐Omics Studies

Titz, B., Lavrynenko, O., & Ivanov, N. V. (2023) · doi:10.1002/9783527836512.ch23

The potential of extracellular vesicle lipid profiling in Alzheimer's disease.Preprint

Su, H., Masters, C. L., Bush, A. I., Barnham, K. J., Reid, G. E., & Vella, L. J. (2023) · doi:10.22541/au.168388562.25020996/v1

Investigation of Early Complex Formation of Huntingtin Protein With and Without Lipids

Stonebraker, A. R. (2023) · The Research Repository @ WVU (West Virginia University) · doi:10.33915/etd.11962

APLICAÇÃO DA LIPIDÔMICA NA DOENÇA DE ALZHEIMER

Silva, E. V. D., Galvão, T. F., Cruz, M. D., & de Oliveira, J. S. (2023) · Revista Foco · doi:10.54751/revistafoco.v16n9-197

Marcadores periféricos de metabolismo de membrana: caracterização de indivíduos com alto risco para psicose

Costa, A. C. (2023) · doi:10.11606/t.5.2023.tde-14092023-143128

Sterol Biomarker Discovery In Neurodegenerative Diseases

Pacciarini, M. (2023) · Cronfa (Swansea University) · doi:10.23889/suthesis.65375

Additional file 1 of Lipidomics profiling reveals distinct patterns of plasma sphingolipid alterations in Alzheimer’s disease and vascular dementia

Chua, X. Y., Torta, F. T., Chong, J. R., Venketasubramanian, N., Hilal, S., Wenk, M. R., Chen, C., Arumugam, T. V., Herr, D. R., & Lai, M. K. P. (2023) · Figshare · doi:10.6084/m9.figshare.24797795

Application of Deep Learning for the Detection of Genetic Variations: Its Implementation in Classifying Alzheimer's Disease

Ugwuanyi, I., Oladoyin, I. A., Anazor, C. V., Dike, I. D., Ezulu, P. C., & Nwagbata, A. (2024) · African Journal of Mathematics and Statistics Studies · doi:10.52589/ajmss-4wnit6f9

Güncel Biyokimya Çalışmaları VII

Atıcı, Y., Ökten, Z., Kasebi, S., Arıkan, B. S., Erdem, M., Kıran, T. R., Yağız, A. K., Aktolun, B., Demirağcı, Y. G., Kara, H., et al. (2024) · Akademisyen Kitabevi eBooks · doi:10.37609/akya.3109

Advancing age, nutraceuticals, and neuroprotection

Woźniak, L. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95735-9.00001-2

Investigating the mechanism of Qifu Yin in ameliorating memory disorders through pseudo-targeted lipidomics

Zhao, F., Wang, J., Wu, M., Fan, J., Liu, S., Deng, F., Wang, S., Cheng, Y., & Wang, Y. (2024) · Molecular Omics · doi:10.1039/d4mo00141a

Mass Spectrometry Applied to Human Cerebrospinal Fluid Lipidome (II)

Millán, L., Fernández‐Irigoyen, J., Santamaría, E., & Mayo, R. (2025) · Methods in molecular biology · doi:10.1007/978-1-0716-4462-1_15

Lipid droplet dysmetabolism affects cell homeostasis in an in vitro model of Alzheimer’s diseasePreprint

Fernandes, T., Caldeira, M. V., Melo, T., Neves, B. B., Carvalho, C., Resende, R., Filadi, R., Pizzo, P., Domingues, M. R., Pereira, C., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.09.658644

Selenium intervention in Alzheimer's disease mice and its possible involvement of the gut-brain axis

Ma, G., Huang, Y., Zeng, K., Yan, X., Ran, X., Liang, Z., Hu, T., Li, J., Wang, M., Sun, Y., et al. (2026) · Journal of Functional Foods · doi:10.1016/j.jff.2026.107301

In vivo inhibition of stearoyl-CoA desaturase modulates the hippocampal fatty acid profile and restores density of dendritic spines in the aggressive 5xFAD model of Alzheimer’s diseasePreprint

Turri, M., Aubin, M., Aumont, A., Vachon, A., Lopez, J. A., Mayhue, M., Plourde, M., & Fernandes, K. J. L. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.27.672447

Lipidomics of Alzheimer’s Disease

Touboul, D., & Gaudin, M. (2014) · Bioanalysis · doi:10.4155/bio.13.346 · Cited by 52

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Kao, Y.-C., Ho, P.-C., Tu, Y.-K., Jou, I.-M., & Tsai, K.-J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21041505 · Cited by 485

Cerebrospinal fluid lipidomics for biomarkers of Alzheimer's disease

Byeon, S. K., Madugundu, A. K., Jain, A., Bhat, F. A., Jung, J. H., Renuse, S., Darrow, J. A., Bakker, A., Albert, M., Moghekar, A., et al. (2021) · Molecular Omics · doi:10.1039/d0mo00186d · Cited by 50

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He, S., Xu, Z., & Han, X. (2025) · Molecular Neurodegeneration · doi:10.1186/s13024-025-00803-6 · Cited by 62

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Wong, M. W. K., Braidy, N., Poljak, A., & Sachdev, P. S. (2016) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000303 · Cited by 50