Malabsorption of L-T4 due to drip coffee: a case report using predictors of causation
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Many cases of drug or food interference can be concealed by an increased daily dose of LT4.
“In addition, many cases of drug or food interference can be concealed by an increased daily dose of LT4 (96).”
From Levothyroxine: conventional and novel drug delivery formulations. (2023) · cites this paper as [96]
Cites
A method for estimating the probability of adverse drug reactions
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Proposal for a New Tool to Evaluate Drug Interaction Cases
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Altered intestinal absorption of L-thyroxine caused by coffee
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Levothyroxine interactions with food and dietary supplements – a systematic review
Wiesner, A., Gajewska, D., & Paśko, P. (2021) · Pharmaceuticals · doi:10.3390/ph14030206 · Cited by 85 · see citing works
“2 per kg Tablets espresso and barley coffee failure to normalize TSH levels Węgrzyn [63] 1, hypothyroid 175 Tablets drip coffee clinical signs of hypothyroidism (TSH level—8.”
BackgroundLevothyroxine: conventional and novel drug delivery formulations.
Liu, H., Li, W., Zhang, W., Sun, S., & Chen, C. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnac030 · Cited by 63 · see citing works
New Formulations of Levothyroxine in the Treatment of Hypothyroidism: Trick or Treat?
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Medications and Food Interfering with the Bioavailability of Levothyroxine: A Systematic Review
Liu, H., Lu, M., Hu, J., Fu, G., Feng, Q., Sun, S., & Chen, C. (2023) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s414460 · Cited by 29 · see citing works
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Food-Drug Interactions: Navigating the Complex Relationship
Ewis, D. K., & El-Sayed, O. S. (2025) · Nutritional neurosciences · doi:10.1007/978-981-95-1983-5_14
Pharmacological Interactions of Levothyroxine in Multiple-Treated Patients
Marco, F. D., & Cusini, C. (2025) · Springer eBooks · doi:10.1007/978-3-032-01700-0_14
- Authors
- Wegrzyn, N. M.
- Corresponding author
- Wegrzyn, Nicole M.
- ORCID
- Wegrzyn, Nicole M.
- Venue
- Journal of the Academy of Nutrition and Dietetics
- Publisher
- Elsevier BV
- Published
- 2016-07
- Volume
- 116
- Issue
- 7
- Pages
- 1073-1076
- ISSN
- 2212-2672 (ISSN-L)
- OpenAlex
- W2312547194
- Cited by
- 9
- References
- 11
- Citations by year
- 2025: 3 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 2
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the Academy of Nutrition and Dietetics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
- Keywords
- levothyroxine, drug malabsorption, coffee consumption, hypothyroidism, overt hypothyroidism, thyroid hormone replacement, drug interactions
- MeSH terms
- Caffeine, Coffee, Diabetes Mellitus, Type 2, Drug Interactions, Fasting, Female, Humans, Hypothyroidism, Malabsorption Syndromes, Middle Aged, Obesity, Morbid, Thyroxine, Hashimoto Disease
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